
β-Scruin, a homologue of the actin crosslinking protein scruin, is
... shows that the repeats at corresponding positions in both proteins have the greatest degree of similarity, i.e. repeat one in α-scruin is most similar to repeat one in β-scruin (Fig. 4A). Secondly, as expected from homology between the N- and Cterminal sequences in both molecules, the next level of ...
... shows that the repeats at corresponding positions in both proteins have the greatest degree of similarity, i.e. repeat one in α-scruin is most similar to repeat one in β-scruin (Fig. 4A). Secondly, as expected from homology between the N- and Cterminal sequences in both molecules, the next level of ...
Membrane Protein Expression in Cell
... Membrane protein synthesis by cell-free expression does not appear to be restricted by origin, size or topology of the target, and its global application is therefore a highly valuable characteristic. The technology is relatively fast to establish in standard biochemical labs, and it does not requir ...
... Membrane protein synthesis by cell-free expression does not appear to be restricted by origin, size or topology of the target, and its global application is therefore a highly valuable characteristic. The technology is relatively fast to establish in standard biochemical labs, and it does not requir ...
Functional expression of lepidopteran
... A toxin gene encoding ButaIT behind a secretory signal sequence from the neuropeptide bombyxin [11,31] was synthesized from synthetic oligonucleotides using baculovirus preference codons for the toxin's amino acid sequence (Fig. 1). The toxin gene was PCR amplified using pfu DNA polymerase and the b ...
... A toxin gene encoding ButaIT behind a secretory signal sequence from the neuropeptide bombyxin [11,31] was synthesized from synthetic oligonucleotides using baculovirus preference codons for the toxin's amino acid sequence (Fig. 1). The toxin gene was PCR amplified using pfu DNA polymerase and the b ...
The genetic basis of inherited anomalies of the teeth: Part 1: Clinical
... Clinical Genetics Unit, Department of Medical Genetics, and INSERM U676, AP-HP, Hôpital Robert Debré, Paris, France ...
... Clinical Genetics Unit, Department of Medical Genetics, and INSERM U676, AP-HP, Hôpital Robert Debré, Paris, France ...
Application of rpoB sequence similarity analysis, REP‐PCR and
... the later gene. Although bootstrap values were lower for the rpoB tree, both phylogenetic analyses shared satisfactory bootstrap support. In terms of the 16S rRNA gene sequences of Geobacillus and Bacillus type strains and isolates, similarity values among 90% and 100% were retrieved, in agreement w ...
... the later gene. Although bootstrap values were lower for the rpoB tree, both phylogenetic analyses shared satisfactory bootstrap support. In terms of the 16S rRNA gene sequences of Geobacillus and Bacillus type strains and isolates, similarity values among 90% and 100% were retrieved, in agreement w ...
DNA barcoding parasite organisms found in terrestrial
... new areas with their level of overall diversity across a region (Martiny et. al. 2006). As this broad and lofty goal, to discover and map worldwide biodiversity, has been identified by the scientific community, several studies have made efforts to map terrestrial and aquatic biodiversity (e.g. Colwe ...
... new areas with their level of overall diversity across a region (Martiny et. al. 2006). As this broad and lofty goal, to discover and map worldwide biodiversity, has been identified by the scientific community, several studies have made efforts to map terrestrial and aquatic biodiversity (e.g. Colwe ...
myostatin
... • Discovered in 1997 by Geneticists Se-Jin Lee and McPherron when they created “Mighty Mice” ...
... • Discovered in 1997 by Geneticists Se-Jin Lee and McPherron when they created “Mighty Mice” ...
Vibrio diabolicus sp. nov., a New Polysaccharide
... polychaete annelid Alvinella pompejana (6), which was collected from a dense population of annelids near the active hydrothermal vent ELSA. While we were searching for marine EPS-secreting bacteria, isolate HE800T was selected because of its ability to exhibit the most interesting swarming mucoid ph ...
... polychaete annelid Alvinella pompejana (6), which was collected from a dense population of annelids near the active hydrothermal vent ELSA. While we were searching for marine EPS-secreting bacteria, isolate HE800T was selected because of its ability to exhibit the most interesting swarming mucoid ph ...
Deciphering the molecular phylogenetics of the Asian honey bee
... sequence data for different Apis species. The tree separates the genomes into 3 main clades. All A. mellifera species were included in one clade, A. cerana species in other clade and A. koschevnikovi and A. florea in another clade. The estimated transition/transversion bias (R) is 0.46. The average ...
... sequence data for different Apis species. The tree separates the genomes into 3 main clades. All A. mellifera species were included in one clade, A. cerana species in other clade and A. koschevnikovi and A. florea in another clade. The estimated transition/transversion bias (R) is 0.46. The average ...
BioACTS Quarter THREE
... scientists to learn from each other? Explain using examples from the discovery of DNA’s structure. ...
... scientists to learn from each other? Explain using examples from the discovery of DNA’s structure. ...
The Arabidopsis RAD51 paralogs RAD51B, RAD51D and XRCC2
... Our results provide strong evidence that Arabidopsis XRCC2, RAD51B and RAD51D have complex functions in somatic DNA repair and gene regulation, arguing for further studies of these ancient genes that have been maintained in both plants and animals during their long evolutionary history. ...
... Our results provide strong evidence that Arabidopsis XRCC2, RAD51B and RAD51D have complex functions in somatic DNA repair and gene regulation, arguing for further studies of these ancient genes that have been maintained in both plants and animals during their long evolutionary history. ...
Brooker Chapter 7 - Volunteer State Community College
... tumor and many cases of colon cancer have both copies of the IGF2 gene expressed (where only one, the father's, should be). Reduced methylation — and hence increased expression — of proto-oncogenes can lead to cancer, while increased methylation — and hence decreased expression — of tumor suppressor ...
... tumor and many cases of colon cancer have both copies of the IGF2 gene expressed (where only one, the father's, should be). Reduced methylation — and hence increased expression — of proto-oncogenes can lead to cancer, while increased methylation — and hence decreased expression — of tumor suppressor ...
PopGen 8: Transient verses equilibrium polymorphism Mutation
... and selection pressure sufficiently large; i.e., Nes >> 1, otherwise beneficial alleles will lost occasionally due to change alone. This means that in real populations, that have finite population sizes, maladaptive alleles can be fixed. The upper limit of the fitness consequences of such alleles wi ...
... and selection pressure sufficiently large; i.e., Nes >> 1, otherwise beneficial alleles will lost occasionally due to change alone. This means that in real populations, that have finite population sizes, maladaptive alleles can be fixed. The upper limit of the fitness consequences of such alleles wi ...
Stochastic Gene Expression:
... We are concerned with two patterns of stochastic gene expression. The first one is in the stochastic initiation of gene expression in a field where gene expression will eventually become homogeneous in all cells. The second is stochastic gene activation that leads to a salt-and-pepper pattern of two ...
... We are concerned with two patterns of stochastic gene expression. The first one is in the stochastic initiation of gene expression in a field where gene expression will eventually become homogeneous in all cells. The second is stochastic gene activation that leads to a salt-and-pepper pattern of two ...
Guidelines for Human Gene Nomenclature (1997)
... of July, 1997. How to distinguish each, in human terms, is no trivial task because many of these genes share structural elements or functional attributes with each other. Added to this problem is the historical pattern of embedding in the names of the genes something about their function, relationsh ...
... of July, 1997. How to distinguish each, in human terms, is no trivial task because many of these genes share structural elements or functional attributes with each other. Added to this problem is the historical pattern of embedding in the names of the genes something about their function, relationsh ...
Structural Domains and Matrix Attachment Regions
... a molecular basis for renewing our pursuit of a possible relationship between gene structure and function. Although some limitations of our analysis and screening approach, at that time, have been acknowledged and discussed (Avramova et al., 1995), most of them have now been overcome, as described b ...
... a molecular basis for renewing our pursuit of a possible relationship between gene structure and function. Although some limitations of our analysis and screening approach, at that time, have been acknowledged and discussed (Avramova et al., 1995), most of them have now been overcome, as described b ...
Axial homeosis and appendicular skeleton defects in mice with a
... a Bluescript-based plasmid. KT3NP4, a 3.1 kb neomycin (neo) resistance cassette driven by the RNA polymerase II promoter, was inserted into a Bst1107I site in the hoxd-11 homeobox (Fig. 1A). This site corresponds to amino acid 23 of the homeodomain so that the insertion disrupts the coding sequence ...
... a Bluescript-based plasmid. KT3NP4, a 3.1 kb neomycin (neo) resistance cassette driven by the RNA polymerase II promoter, was inserted into a Bst1107I site in the hoxd-11 homeobox (Fig. 1A). This site corresponds to amino acid 23 of the homeodomain so that the insertion disrupts the coding sequence ...
08.seg_dup_els - NYU Computer Science
... full generality. For instance, the rates of gene duplication and deletion in different genomes had been quantified and found to be at a similar scale to the substitution rate [Lynch & Conery (2000)]. For instance, these studies had resulted in some understanding of the fate of the duplicated genes: ...
... full generality. For instance, the rates of gene duplication and deletion in different genomes had been quantified and found to be at a similar scale to the substitution rate [Lynch & Conery (2000)]. For instance, these studies had resulted in some understanding of the fate of the duplicated genes: ...
histidine and cysteine can enhance the metabolic reaction rates in
... one order of magnitude than that of histidine, which showed a specific relationship between an amino acid and an anticodon, namely the stereochemical theory of the genetic code. I have also shown in a separate letter [3] that not only histidine but other single amino acids such as cysteine, glutamic ...
... one order of magnitude than that of histidine, which showed a specific relationship between an amino acid and an anticodon, namely the stereochemical theory of the genetic code. I have also shown in a separate letter [3] that not only histidine but other single amino acids such as cysteine, glutamic ...
(HPV) L1 gene DNA possibly bound to particulate aluminum
... into the antigen-presenting cells or macrophages after injection. Their physical condition in the vaccine may determine the fate of these foreign DNA fragments in a vaccinated person and their variable physiopathological effects on the host. Different inorganic aluminum compounds with their specific ...
... into the antigen-presenting cells or macrophages after injection. Their physical condition in the vaccine may determine the fate of these foreign DNA fragments in a vaccinated person and their variable physiopathological effects on the host. Different inorganic aluminum compounds with their specific ...
Construction of a pBAD24 Vector Containing σ32 : Restoration of
... shock proteins (HSPs). HSPs exhibit sophisticated mechanisms to protect and maintain normal cellular functions, which include preventing non-specific protein aggregation as well as repairing misfolded proteins (1). In E. coli, the heat shock genes are functionally divided into two regulons, one of w ...
... shock proteins (HSPs). HSPs exhibit sophisticated mechanisms to protect and maintain normal cellular functions, which include preventing non-specific protein aggregation as well as repairing misfolded proteins (1). In E. coli, the heat shock genes are functionally divided into two regulons, one of w ...
Siberian Sunshine - AFeF Associazioni Feline Federate
... Starting, mainly from “Onix Gloria” lines, you can find the golden tabby ones, but it is immediately evident that “golden” cats are born out two parents which are “not golden”. The golden colour is a colour which, traditionally, has been selected mainly in Persian cats and it's given by the gene W ...
... Starting, mainly from “Onix Gloria” lines, you can find the golden tabby ones, but it is immediately evident that “golden” cats are born out two parents which are “not golden”. The golden colour is a colour which, traditionally, has been selected mainly in Persian cats and it's given by the gene W ...
Insilico Studies on Taste Receptor Gene (Tas2r38) and Tas2r38
... Taste Receptor 2 member 38 is a protein that in humans are encoded by the TAS2R38 gene [2],[3]. Three common Single Nucleotide Polymorphisms (SNPs) were identified in this gene, which is at base pairs 145 (C-G), 785 (C-T) and 886 (G-A), resulting in 3 amino acid substitutions at codons P49A, A262V, ...
... Taste Receptor 2 member 38 is a protein that in humans are encoded by the TAS2R38 gene [2],[3]. Three common Single Nucleotide Polymorphisms (SNPs) were identified in this gene, which is at base pairs 145 (C-G), 785 (C-T) and 886 (G-A), resulting in 3 amino acid substitutions at codons P49A, A262V, ...
Multilevel functional and structural defects induced by two
... with a wide range of pathologies. During the last two decades, an increasing number of single nucleotide substitutions within the hmtRNA genes have been linked to a variety of diseases showing pleiotropic effects. More than 220 mutations have been associated with diseases in the 22 genes of hmtRNAs ...
... with a wide range of pathologies. During the last two decades, an increasing number of single nucleotide substitutions within the hmtRNA genes have been linked to a variety of diseases showing pleiotropic effects. More than 220 mutations have been associated with diseases in the 22 genes of hmtRNAs ...
Point mutation

A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.