
Poster: Litter size in Norwegian White Sheep
... In 2011 we realized that a mutation in the GDF9 gene (c.1111G>A or V371M) is associated with an increase in litter size. The mutation increases the litter size by approximately 0.3 lambs per copy of the allele. The variance in litter size increases with the mean. 850 ewes from flocks with both a hig ...
... In 2011 we realized that a mutation in the GDF9 gene (c.1111G>A or V371M) is associated with an increase in litter size. The mutation increases the litter size by approximately 0.3 lambs per copy of the allele. The variance in litter size increases with the mean. 850 ewes from flocks with both a hig ...
The UCSC Known Genes
... In Addition, direct links between RefSeq genes and Swiss-Prot proteins were not available. Hence we decided to develop an automated process to construct the UCSC Known Genes dataset based on the latest protein data from Swiss-Prot/TrEMBL (Bairoch et al., 2005), now also known as UniProt, and the ass ...
... In Addition, direct links between RefSeq genes and Swiss-Prot proteins were not available. Hence we decided to develop an automated process to construct the UCSC Known Genes dataset based on the latest protein data from Swiss-Prot/TrEMBL (Bairoch et al., 2005), now also known as UniProt, and the ass ...
Slide 1
... • Genes can be mapped by linkage studies with polymorphic markers • which are nucleotide sequences identifiable at specific sites along the genome • Numerous markers have been identified throughout the genome using restriction endonucleases • and so it is possible to construct maps of disease genes ...
... • Genes can be mapped by linkage studies with polymorphic markers • which are nucleotide sequences identifiable at specific sites along the genome • Numerous markers have been identified throughout the genome using restriction endonucleases • and so it is possible to construct maps of disease genes ...
Conformational Preferences of Amino Acids in Globular Proteins?
... (sets I and III) are more similar to each another than they are to P, values derived without weights (set II). The effect of using the most reliable secondary structure assignment is smaller (compare Pij values in sets I and II); 75 of the 1790 a-helical residues and 402 of the 1957 P-sheet residues ...
... (sets I and III) are more similar to each another than they are to P, values derived without weights (set II). The effect of using the most reliable secondary structure assignment is smaller (compare Pij values in sets I and II); 75 of the 1790 a-helical residues and 402 of the 1957 P-sheet residues ...
Deletion of the gene encoding the reductase component of 3
... resulting in the formation of 4-cholesten-3-one. However, recent studies on some Mycobacterium strains suggested that 3-hydroxysteroid dehydrogenase, rather than cholesterol oxidase, is responsible for the first step oxidation [5,6]. The degradation continues with side chain cleavage, taking place v ...
... resulting in the formation of 4-cholesten-3-one. However, recent studies on some Mycobacterium strains suggested that 3-hydroxysteroid dehydrogenase, rather than cholesterol oxidase, is responsible for the first step oxidation [5,6]. The degradation continues with side chain cleavage, taking place v ...
Classification for a Phenotype
... phenotypic diagnosis. More than 60 disease genes have been identified to date [9]; genes such as MYBPC3 may be associated with different phenotypes (HCM, RCM, DCM), and genes such as DYS may cause a unique phenotype (DCM only). The penetrance of the genetic mutation is variable, and phenotypic manife ...
... phenotypic diagnosis. More than 60 disease genes have been identified to date [9]; genes such as MYBPC3 may be associated with different phenotypes (HCM, RCM, DCM), and genes such as DYS may cause a unique phenotype (DCM only). The penetrance of the genetic mutation is variable, and phenotypic manife ...
Neuropharmacological effects of triterpenoids
... Plants biosynthesize diverse group of triterpenoids. As described in Figure 2, the terpenes biosynthesis can be divided into four distinct stages. Initial or the first stage involves the formation of isopentenyl diphosphate that is basic building block for isoprenoids (Gershenzon and Kreis, 1999). S ...
... Plants biosynthesize diverse group of triterpenoids. As described in Figure 2, the terpenes biosynthesis can be divided into four distinct stages. Initial or the first stage involves the formation of isopentenyl diphosphate that is basic building block for isoprenoids (Gershenzon and Kreis, 1999). S ...
use of genomic tools to discover the cause of
... SLC36A1 encodes a eukaryote specific proton dependent small amino acid transporter also known as LYAAT-1 in rats. This change in base 188 of the cDNA from a C to a G (Genbank REFSEQ: Non-champagne EU432176 and Champagne EU432177), is predicted to cause an amino acid change from threonine to arginine ...
... SLC36A1 encodes a eukaryote specific proton dependent small amino acid transporter also known as LYAAT-1 in rats. This change in base 188 of the cDNA from a C to a G (Genbank REFSEQ: Non-champagne EU432176 and Champagne EU432177), is predicted to cause an amino acid change from threonine to arginine ...
Low-temperature anaerobic digestion is associated with differential
... McKeown et al. 2009). Although important insights have been gathered (e.g. Methanocorpusculum prevalence during AD operation at 15◦ C; McKeown et al. 2009), minimal information relating methanogenic presence to functional significance (metabolic pathways employed, physiological responses etc.) has b ...
... McKeown et al. 2009). Although important insights have been gathered (e.g. Methanocorpusculum prevalence during AD operation at 15◦ C; McKeown et al. 2009), minimal information relating methanogenic presence to functional significance (metabolic pathways employed, physiological responses etc.) has b ...
VECTOR SYSTEMS XXVII.indd
... Product Description Our Bacillus megaterium kit is a new easy-to-handle system for stable protein expression with high yield. It is not only suited for industrial large scale protein production, but offers also an interesting alternative to the standard host E. coli. The kit comes with the E. coli/B ...
... Product Description Our Bacillus megaterium kit is a new easy-to-handle system for stable protein expression with high yield. It is not only suited for industrial large scale protein production, but offers also an interesting alternative to the standard host E. coli. The kit comes with the E. coli/B ...
Acetobactev diazotrophicus sp. nov., a Nitrogen
... gamma subclass of the Proteobacteria (13). This means that they are not related to the genus Frateuria, which is located on the Xanthomonas rRNA branch ( 5 , 14). With 23s [I4C]rRNA from Gluconobacter oxydans NCIB 9013T we found mean Tmt,, values of 76.1 and 77.0”C for strains PPe 4 and PA1 5T, resp ...
... gamma subclass of the Proteobacteria (13). This means that they are not related to the genus Frateuria, which is located on the Xanthomonas rRNA branch ( 5 , 14). With 23s [I4C]rRNA from Gluconobacter oxydans NCIB 9013T we found mean Tmt,, values of 76.1 and 77.0”C for strains PPe 4 and PA1 5T, resp ...
Prof. Kamakaka`s Lecture 16 Notes
... for the regulation of this operon. Input from other environmental factors, such as the presence of glucose, could not be accounted for. Eventually it was realized that some catalytic breakdown product of glucose prevented the activation of the lac operon even in the presence of lactose. This effect ...
... for the regulation of this operon. Input from other environmental factors, such as the presence of glucose, could not be accounted for. Eventually it was realized that some catalytic breakdown product of glucose prevented the activation of the lac operon even in the presence of lactose. This effect ...
Enzymes
... An important function of enzymes is in the digestive systems of animals. Enzymes such as amylases and proteases break down large molecules (starch or proteins, respectively) into smaller ones, so they can be absorbed by the intestines. Starch molecules, for example, are too large to be absorbed from ...
... An important function of enzymes is in the digestive systems of animals. Enzymes such as amylases and proteases break down large molecules (starch or proteins, respectively) into smaller ones, so they can be absorbed by the intestines. Starch molecules, for example, are too large to be absorbed from ...
07-050sr (Microsoft Word
... "(c) it is conducted in accordance with applicable technical and procedural guidelines, as in force from time to time under section 27(d) of the Act, relating to— (i) containment of the GMO; and (ii) if the dealing involves transporting the GMO, transport; and (d) it does not involve an intentional ...
... "(c) it is conducted in accordance with applicable technical and procedural guidelines, as in force from time to time under section 27(d) of the Act, relating to— (i) containment of the GMO; and (ii) if the dealing involves transporting the GMO, transport; and (d) it does not involve an intentional ...
A pesticide that was rarely used in 1932 was used with increasing
... To test this hypothesis, scientists conducted an experiment to determine the effect of the waterborne chemicals produced by Asian shore crabs on southern and northern blue mussels. Southern and northern blue mussels were exposed to the unique waterborne chemicals produced by green crabs and Asian sh ...
... To test this hypothesis, scientists conducted an experiment to determine the effect of the waterborne chemicals produced by Asian shore crabs on southern and northern blue mussels. Southern and northern blue mussels were exposed to the unique waterborne chemicals produced by green crabs and Asian sh ...
Solid Tumour Section Esophagus: Barrett's esophagus, dysplasia and adenocarcinoma
... CGH analysis of a case of Barrett's esophageal adenocarcinoma. Tumor DNA was labeled with FITC (Green) and reference DNA was labeled with TRITC (red). The hybridizations were analyzed using an Olympus fluorescence microscope and the ISIS digital image analysis system (Metasystems GmbH, Altlussheim, ...
... CGH analysis of a case of Barrett's esophageal adenocarcinoma. Tumor DNA was labeled with FITC (Green) and reference DNA was labeled with TRITC (red). The hybridizations were analyzed using an Olympus fluorescence microscope and the ISIS digital image analysis system (Metasystems GmbH, Altlussheim, ...
View
... induce the stalling and collapse of replication forks, which in turn leads to DSB formation (10,11). Increased formation of DSBs brings about a high demand for DNA damage response. Activated DNA repair response, as represented by H2AX phosphorylation, was observed in both precancerous and cancer cel ...
... induce the stalling and collapse of replication forks, which in turn leads to DSB formation (10,11). Increased formation of DSBs brings about a high demand for DNA damage response. Activated DNA repair response, as represented by H2AX phosphorylation, was observed in both precancerous and cancer cel ...
Testis-specific TAF homologs collaborate to control a
... Flies null mutant for can are viable and female fertile but male sterile. The requirement for can function is gene selective: only a specific set of genes normally expressed in wild-type primary spermatocytes are affected, while a number of other genes are transcribed normally in spermatocytes from ...
... Flies null mutant for can are viable and female fertile but male sterile. The requirement for can function is gene selective: only a specific set of genes normally expressed in wild-type primary spermatocytes are affected, while a number of other genes are transcribed normally in spermatocytes from ...
Alzheimer`s Disease Genetics Fact Sheet
... person inherits the mutated gene that causes one of these disorders, he or she will usually get the disease. AD, on the other hand, is not caused by a single gene. More than one gene mutation can cause AD, and genes on multiple chromosomes are involved. ...
... person inherits the mutated gene that causes one of these disorders, he or she will usually get the disease. AD, on the other hand, is not caused by a single gene. More than one gene mutation can cause AD, and genes on multiple chromosomes are involved. ...
Cat Health Network Feline SNP Chip Studies Lay Language
... health. The tailless mutation of the Manx cat breed affects spine and tail development, the breed being purposely selected to have no tail. If the tail is too short, vertebrae of the lower back are missing, leading to poor development of nerves, thus cats can be lame and not be able to control their ...
... health. The tailless mutation of the Manx cat breed affects spine and tail development, the breed being purposely selected to have no tail. If the tail is too short, vertebrae of the lower back are missing, leading to poor development of nerves, thus cats can be lame and not be able to control their ...
The tightly regulated promoter of the xanA gene of
... have shown that this enzyme is responsible for the utilization of xanthine as nitrogen source in Schizosaccharomyces pombe, which lacks xanthine dehydrogenase, and homologues are present in a number of fungi, including many yeasts able to utilize oxidized purines as sole nitrogen sources. Many fungi ...
... have shown that this enzyme is responsible for the utilization of xanthine as nitrogen source in Schizosaccharomyces pombe, which lacks xanthine dehydrogenase, and homologues are present in a number of fungi, including many yeasts able to utilize oxidized purines as sole nitrogen sources. Many fungi ...
Heinrichs, V., and Baker, B. S.
... The identification of the functional domains in SR proteins necessary for the regulation of alternative splicing can help to understand which molecular interactions are required in splicing regulation. Both binding of SR proteins to their target pre-mRNAs and protein–protein interactions of SR prote ...
... The identification of the functional domains in SR proteins necessary for the regulation of alternative splicing can help to understand which molecular interactions are required in splicing regulation. Both binding of SR proteins to their target pre-mRNAs and protein–protein interactions of SR prote ...
A set reduction and pattern matching problem motivated by Allele
... region by a DNA polymerase which extends the primer sequence and creates two copies of the flanked region. This process is repeated many times causing exponential amplification of the sequence and ensuring it is present in detectable levels (Fig. 1). Allelic variants—different sets of alleles in an ...
... region by a DNA polymerase which extends the primer sequence and creates two copies of the flanked region. This process is repeated many times causing exponential amplification of the sequence and ensuring it is present in detectable levels (Fig. 1). Allelic variants—different sets of alleles in an ...
Chapter 17 Lecture PowerPoint - McGraw Hill Higher Education
... • Translation is the process by which ribosomes read the genetic message in mRNA and produce a protein product according to the message • Ribosomes are protein factories • Transfer RNAs (tRNAs) play an important role as adaptors that can bind and amino acid at one end and interact with the mRNA at t ...
... • Translation is the process by which ribosomes read the genetic message in mRNA and produce a protein product according to the message • Ribosomes are protein factories • Transfer RNAs (tRNAs) play an important role as adaptors that can bind and amino acid at one end and interact with the mRNA at t ...
Point mutation

A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.