amino acids and proteins
... • It is the pH at which there is no net charge on the amino acid. It is denoted pI. • Each amino acid has a specific pI and this has been the basis for precipitation of amino acids. • At certain pH values, the amino acid may move either to the anode or cathode in an electric field depending in the c ...
... • It is the pH at which there is no net charge on the amino acid. It is denoted pI. • Each amino acid has a specific pI and this has been the basis for precipitation of amino acids. • At certain pH values, the amino acid may move either to the anode or cathode in an electric field depending in the c ...
One of the crucial proteins to influence type 2 diabetes
... et al., 2011). INSR protein expression and insulin-binding capacity are also restored in lymphoblasts obtained from diabetic IVS5-13insC carriers through HMGA1 DNA transfection. On the other hand, IVS5-13insC does not affect HMGA1 or INSR expression in adipose tissues of normoglycemic patients(Marqu ...
... et al., 2011). INSR protein expression and insulin-binding capacity are also restored in lymphoblasts obtained from diabetic IVS5-13insC carriers through HMGA1 DNA transfection. On the other hand, IVS5-13insC does not affect HMGA1 or INSR expression in adipose tissues of normoglycemic patients(Marqu ...
Biogenesis and significance of lipofuscin in the equine thyroid gland
... histochemistry. They increase in number with age in post-mitotic cells, and are regarded as markers of the aging process. Lipofuscin is widely assumed to consist of products of peroxidised fatty acids cross-linked with amino groups of proteins, nucleic acids, and phospholipids, but this theory has n ...
... histochemistry. They increase in number with age in post-mitotic cells, and are regarded as markers of the aging process. Lipofuscin is widely assumed to consist of products of peroxidised fatty acids cross-linked with amino groups of proteins, nucleic acids, and phospholipids, but this theory has n ...
2.2.56. amino acid analysis
... amino acid analysis of these molecules. The glassware used for hydrolysis must be very clean to avoid erroneous results. Glove powders and fingerprints on hydrolysis tubes may cause contamination. To clean glass hydrolysis tubes, boil tubes for 1 h in 1 M hydrochloric acid or soak tubes in concentra ...
... amino acid analysis of these molecules. The glassware used for hydrolysis must be very clean to avoid erroneous results. Glove powders and fingerprints on hydrolysis tubes may cause contamination. To clean glass hydrolysis tubes, boil tubes for 1 h in 1 M hydrochloric acid or soak tubes in concentra ...
Amino acid alterations essential for increasing the catalytic activity of
... acid alterations that affect the catalytic activity, we constructed further hybrid plasmids from pHK7 (to identify the alterations in the residues 162 - 257 region) and from pHK8d 11 (to identify the alterations in the residues 258 -380 region), then the alterations thus identified were introduced i ...
... acid alterations that affect the catalytic activity, we constructed further hybrid plasmids from pHK7 (to identify the alterations in the residues 162 - 257 region) and from pHK8d 11 (to identify the alterations in the residues 258 -380 region), then the alterations thus identified were introduced i ...
Integrated Microbial Genomes
... structural and functional details on each COG and literature references, improvements of the COGNITOR program that is used to fit new proteins into the COGs, and classification of genomes and COGs constructed by ...
... structural and functional details on each COG and literature references, improvements of the COGNITOR program that is used to fit new proteins into the COGs, and classification of genomes and COGs constructed by ...
Gekko 4_1 July 29
... between the tyrosinase positive albinism in leopard geckos, for example, and several human and murine forms of oculocutaneous albinism, an assortment of disorders that result in reduced or no melanin production. Oculocutaneous albinism 1 (OCA1) is caused by mutations of the tyrosinase gene. One vari ...
... between the tyrosinase positive albinism in leopard geckos, for example, and several human and murine forms of oculocutaneous albinism, an assortment of disorders that result in reduced or no melanin production. Oculocutaneous albinism 1 (OCA1) is caused by mutations of the tyrosinase gene. One vari ...
Overview of testing for Lynch syndrome/HNPCC
... it was not performed because these types of mutations are common in the LS gene. • If there is a known LS gene mutation in the family, the result is considered a “true negative,” and the individual can follow guidelines for cancer screening in the general population as long as he or she does not ha ...
... it was not performed because these types of mutations are common in the LS gene. • If there is a known LS gene mutation in the family, the result is considered a “true negative,” and the individual can follow guidelines for cancer screening in the general population as long as he or she does not ha ...
R4, a non-LTR retrotransposon specific to the
... the H.contortus 26S gene sequence was found to have a base substitution at the first position downstream of the insertion site. Thus the insertions in H.contortus are at the identical position as the insertions in A.lumbricoides and P.equorum. Other variations detected within the 26S genes were sing ...
... the H.contortus 26S gene sequence was found to have a base substitution at the first position downstream of the insertion site. Thus the insertions in H.contortus are at the identical position as the insertions in A.lumbricoides and P.equorum. Other variations detected within the 26S genes were sing ...
Improving Virus C type 4 Interferon using Bioinformatics Techniques
... the protein that is being synthesized as an elongating chain of amino acid residues, using the information on the mRNA to "know" which amino acid should be put on next. For each kind of amino acid, there is a specific tRNA that will recognize the amino acid and transport it to the protein that is be ...
... the protein that is being synthesized as an elongating chain of amino acid residues, using the information on the mRNA to "know" which amino acid should be put on next. For each kind of amino acid, there is a specific tRNA that will recognize the amino acid and transport it to the protein that is be ...
A Classification of Microarray Gene Expression Data Using
... expression levels of huge number of different genes simultaneously [9]. It is possible for the biologists to concurrently evaluate the expressions of thousands of genes in a single experiment by the aid of microarray technologies [5] [15] [19]. This technology provides a unique tool, which has been ...
... expression levels of huge number of different genes simultaneously [9]. It is possible for the biologists to concurrently evaluate the expressions of thousands of genes in a single experiment by the aid of microarray technologies [5] [15] [19]. This technology provides a unique tool, which has been ...
Highly precise and developmentally programmed genome
... extensive genome rearrangements take place in the new MAC during this process. In Paramecium tetraurelia, MAC development involves DNA amplification (from 2n to 800–1000n) and elimination of two types of germline sequences. Regions extending up to several kb, often including repeated DNA, are elimin ...
... extensive genome rearrangements take place in the new MAC during this process. In Paramecium tetraurelia, MAC development involves DNA amplification (from 2n to 800–1000n) and elimination of two types of germline sequences. Regions extending up to several kb, often including repeated DNA, are elimin ...
(EC 2.2.1.1) active in the Calvin cycle of spinach chloroplasts
... Comparatively little is known about the plant transketolase enzyme. Some previous studies indicated that higher plants in general might possess chloroplast and cytosolic TKL isoenzymes [21, 29], whereas others reported that most, if not all, TKL activity is localized to the chloroplast, at least in ...
... Comparatively little is known about the plant transketolase enzyme. Some previous studies indicated that higher plants in general might possess chloroplast and cytosolic TKL isoenzymes [21, 29], whereas others reported that most, if not all, TKL activity is localized to the chloroplast, at least in ...
Direct interaction between the Rice yellow mottle virus (RYMV) VPg
... 2000, Schaad et al., 2000, Wittmann et al., 1997). The resistant phenotypes result from disruptions of the interactions between eIF4Es and VPgs (Charron et al., 2008, Kang et al., 2005a, Yeam et al., 2007). However, recessive resistance can sometimes be overcome by the emergence of virulent variants ...
... 2000, Schaad et al., 2000, Wittmann et al., 1997). The resistant phenotypes result from disruptions of the interactions between eIF4Es and VPgs (Charron et al., 2008, Kang et al., 2005a, Yeam et al., 2007). However, recessive resistance can sometimes be overcome by the emergence of virulent variants ...
13) PHENOTYPE: the set of observable characteristics of an
... 11a) DOMINANT ALLELE: its trait will “win” when at least one of the paired alleles is dominant. 11b) RECESSIVE ALLELE: its trait will “win” only when both paired alleles are recessive ...
... 11a) DOMINANT ALLELE: its trait will “win” when at least one of the paired alleles is dominant. 11b) RECESSIVE ALLELE: its trait will “win” only when both paired alleles are recessive ...
Introduction
... • try to find some function which often works • do not stick to real physics Will my drug dissolve in water or oil (lipid) ? (important) • sounds like chemistry • usually approached by machine learning • number of atoms, types of atoms, … http://www.cgl.ucsf.edu/chimera/ImageGallery/, bluetongue vir ...
... • try to find some function which often works • do not stick to real physics Will my drug dissolve in water or oil (lipid) ? (important) • sounds like chemistry • usually approached by machine learning • number of atoms, types of atoms, … http://www.cgl.ucsf.edu/chimera/ImageGallery/, bluetongue vir ...
Gene conversion rapidly generates major histocompatibility complex
... Following a population bottleneck, novel genetic diversity may be introduced by migration or mutation. In isolated populations where migration rates are low, ...
... Following a population bottleneck, novel genetic diversity may be introduced by migration or mutation. In isolated populations where migration rates are low, ...
nature of polyethyleneimine-glucose oxidase interactions
... Based on the best docked energies: -5.8 and -4.5 kcal/mol, two sites were differentiated on the protein body, which show the best affinity to PEI (Table 1). In the first case, the ligand is bound to amino acids inside of the protein area (LIG1, Figure 5), while in the second case the binding takes p ...
... Based on the best docked energies: -5.8 and -4.5 kcal/mol, two sites were differentiated on the protein body, which show the best affinity to PEI (Table 1). In the first case, the ligand is bound to amino acids inside of the protein area (LIG1, Figure 5), while in the second case the binding takes p ...
here - Genetics
... o r more base-pair positions, and since any of four different base-pairs may occupy any one position, the number of possible mutant alleles is very large. It is important that each mutant allele of a particular locus be given a unique designation; e.g., by the use of serial numbers as suffixes. Use ...
... o r more base-pair positions, and since any of four different base-pairs may occupy any one position, the number of possible mutant alleles is very large. It is important that each mutant allele of a particular locus be given a unique designation; e.g., by the use of serial numbers as suffixes. Use ...
here - FasterDB
... Figure 12. Comparison of PTB Binding Sites between Human exon 13 and its orthologous exon in the mouse genome (exon 15) among the WNK gene (A). CLIP-seq data for PTB at the exon level (B). Exon Arrays visualization when PTB is depleted in the Human (C) and Mouse (D). A. For each exon and 200 nucleot ...
... Figure 12. Comparison of PTB Binding Sites between Human exon 13 and its orthologous exon in the mouse genome (exon 15) among the WNK gene (A). CLIP-seq data for PTB at the exon level (B). Exon Arrays visualization when PTB is depleted in the Human (C) and Mouse (D). A. For each exon and 200 nucleot ...
Mapping of the Recessive White Locus and
... all-white plumage, whereas the wild type (C+) has strong pigmentation. A previous study using 2-dimensional gel electrophoresis suggested that the C locus is the structural locus for tyrosinase in the fowl (Oetting et al., 1985). The tyrosinase gene in chickens has been cloned by Mochii et al. (1992 ...
... all-white plumage, whereas the wild type (C+) has strong pigmentation. A previous study using 2-dimensional gel electrophoresis suggested that the C locus is the structural locus for tyrosinase in the fowl (Oetting et al., 1985). The tyrosinase gene in chickens has been cloned by Mochii et al. (1992 ...
Structure of the Coat Protein-binding Domain of
... Electrostatic interactions are somewhat nonspeci®c, especially when they do not involve a single pair of oppositely charged residues. However, this type of interaction, active over long distances, would serve well for the initial recognition and binding events. In order to lock the scaffolding and c ...
... Electrostatic interactions are somewhat nonspeci®c, especially when they do not involve a single pair of oppositely charged residues. However, this type of interaction, active over long distances, would serve well for the initial recognition and binding events. In order to lock the scaffolding and c ...
Generation and analysis of mutated clonal scFv Jiya George
... Figure 20: A: Agarose gel electrophoresis (1%) of pAK400 phage DNA B: Agarose gel electrophoresis (1%) of SfiI restriction enzyme digested pAK400 phage DNA ..................... 62 Figure 21: A: Agarose gel electrophoresis (1%) of pAKR7V400 phage DNA B: Agarose gel electrophoresis (1%) confirming th ...
... Figure 20: A: Agarose gel electrophoresis (1%) of pAK400 phage DNA B: Agarose gel electrophoresis (1%) of SfiI restriction enzyme digested pAK400 phage DNA ..................... 62 Figure 21: A: Agarose gel electrophoresis (1%) of pAKR7V400 phage DNA B: Agarose gel electrophoresis (1%) confirming th ...
Insertional inactivation studies of the csmA and csmC genes of the
... Arrows indicate the direction of transcription. Abbreviations for restriction enzymes : A, AvaI ; N, NcoI; Sa, SalI; Sp, SphI. B and C: Southern blot hybridization analyses. Total genomic DNA in lanes 1^3 was digested with NcoI and SalI, and the DNA in lanes 4 and 5 was digested with HindIII. Lane 1 ...
... Arrows indicate the direction of transcription. Abbreviations for restriction enzymes : A, AvaI ; N, NcoI; Sa, SalI; Sp, SphI. B and C: Southern blot hybridization analyses. Total genomic DNA in lanes 1^3 was digested with NcoI and SalI, and the DNA in lanes 4 and 5 was digested with HindIII. Lane 1 ...
Point mutation
A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.