Bio2 Gene prediction DNA structure Codons and ORFs Predicting
... of this approach: • HMMs can be visualised as finite state machines with a begin and an end state. • FSMs move through a series of state emitting some kind of output report either at the end or during a transition from one state to another. ...
... of this approach: • HMMs can be visualised as finite state machines with a begin and an end state. • FSMs move through a series of state emitting some kind of output report either at the end or during a transition from one state to another. ...
pO 2
... Allosteric interaction - the binding of one ligand at one site in a protein that affects the binding of other ligands at other sites in the protein. This can be affect on binding can be cooperative (pos or neg). Allosterism is typically seen when sigmoidal binding / activity curves. ...
... Allosteric interaction - the binding of one ligand at one site in a protein that affects the binding of other ligands at other sites in the protein. This can be affect on binding can be cooperative (pos or neg). Allosterism is typically seen when sigmoidal binding / activity curves. ...
protease (NS34A) and an RNA polymerase
... modified such that it could not act directly as a substrate in ubiquitination. This implies that phospho-ubiquitin binds to and activates parkin separately from its role as a substrate. Clues as to how this could be achieved might be gleaned from recent crystallographic analyses of parkin11,12. A ph ...
... modified such that it could not act directly as a substrate in ubiquitination. This implies that phospho-ubiquitin binds to and activates parkin separately from its role as a substrate. Clues as to how this could be achieved might be gleaned from recent crystallographic analyses of parkin11,12. A ph ...
Molecular Microbiology
... key amino acid residues (histidine, glutamic acid and cysteine), that is identical to that of the C55 family of cysteine proteases (Barrett and Rawlings, 2001). However, YopJ has been shown to possess an acetyltransferase activity and suppress host immune response in animals by blocking the activati ...
... key amino acid residues (histidine, glutamic acid and cysteine), that is identical to that of the C55 family of cysteine proteases (Barrett and Rawlings, 2001). However, YopJ has been shown to possess an acetyltransferase activity and suppress host immune response in animals by blocking the activati ...
Alternative routes of acetyl-CoA synthesis identified
... sequences of the oleaginous microbes were distributed over several processes of the cells. Based on the 41 sequences categorized by metabolism, putative routes potentially involved in the generation of precursors for fatty acid and lipid synthesis, particularly acetyl-CoA, were then identified that ...
... sequences of the oleaginous microbes were distributed over several processes of the cells. Based on the 41 sequences categorized by metabolism, putative routes potentially involved in the generation of precursors for fatty acid and lipid synthesis, particularly acetyl-CoA, were then identified that ...
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI
... (ii) Increasing tyrosyl –tRNA synthetase activity by protein engineering (28) Discuss the following: (i) Enzyme replacement therapy for cancer (ii) Enzymes used in the alcohol and starch industry (29) Explain the following: (i) Glucose-6-phosphate dehydrogenase deficiency (ii) Enzymes in the diagnos ...
... (ii) Increasing tyrosyl –tRNA synthetase activity by protein engineering (28) Discuss the following: (i) Enzyme replacement therapy for cancer (ii) Enzymes used in the alcohol and starch industry (29) Explain the following: (i) Glucose-6-phosphate dehydrogenase deficiency (ii) Enzymes in the diagnos ...
lncRNA in
... • Three methods for finding protein coding evidence – Protein sequence similarity – Coding Potential Calculator (CPC) – Coding-Potential Assessment Tool (CPAT) ...
... • Three methods for finding protein coding evidence – Protein sequence similarity – Coding Potential Calculator (CPC) – Coding-Potential Assessment Tool (CPAT) ...
Active site mapping, biochemical properties and
... with a 1–5% mortality. The sole new drug is eflornithine (DL-a-difluoromethylornithine, DFMO), a selective inhibitor of ornithine decarboxylase. First used in 1990, eflornithine is effective against T. b. gambiense but ineffective against T. b. rhodesiense [5]. Clearly, new strategies to treat sleep ...
... with a 1–5% mortality. The sole new drug is eflornithine (DL-a-difluoromethylornithine, DFMO), a selective inhibitor of ornithine decarboxylase. First used in 1990, eflornithine is effective against T. b. gambiense but ineffective against T. b. rhodesiense [5]. Clearly, new strategies to treat sleep ...
GLYCOLIPID ANCHORING OF CELL SURFACE PROTEINS Mark C
... experiments, or on the sensitivity of the protein to enzyme cleavage. The methods used will depend on factors such as abundance, availability of a rigorous purification protocol, and of monospecific antibodies. Composition analysis for ethanolamine can be performed using an amino acid analyser, and ...
... experiments, or on the sensitivity of the protein to enzyme cleavage. The methods used will depend on factors such as abundance, availability of a rigorous purification protocol, and of monospecific antibodies. Composition analysis for ethanolamine can be performed using an amino acid analyser, and ...
Lec5 Lipoproteins
... • There are five major classes ( from A-E) of apoproteins – divided by structure & function – Each class has subclasses e.g. Apo A1, Apo CII – Functions of apoproteins • Some are required as structural proteins e.g.B48, B100 • Some are activators, e.g. Apo CII • Some are recognition sites (recognize ...
... • There are five major classes ( from A-E) of apoproteins – divided by structure & function – Each class has subclasses e.g. Apo A1, Apo CII – Functions of apoproteins • Some are required as structural proteins e.g.B48, B100 • Some are activators, e.g. Apo CII • Some are recognition sites (recognize ...
Lesson 8. Enzymes
... protein, except for a class of RNA modifying catalysts known as ribozymes. Ribozymes are molecules of ribonucleic acid that catalyze reactions on the phosphodiester bond of other RNAs. Enzymes are found in all tissues and fluids of the body. Intracellular enzymes catalyze the reactions of metabolic ...
... protein, except for a class of RNA modifying catalysts known as ribozymes. Ribozymes are molecules of ribonucleic acid that catalyze reactions on the phosphodiester bond of other RNAs. Enzymes are found in all tissues and fluids of the body. Intracellular enzymes catalyze the reactions of metabolic ...
Sugar Signaling and Proteolysis in Higher Plants
... and A3), but did not activate the expression of sugar up-regulated genes (Ho et al. 2001). Sugarstarved sycamore cells incubated in the presence of Glyc or pyruvate stopped growing but were able to survive for weeks in the absence of any gluconeogenesis and did not display autophagy symptoms (Aubert ...
... and A3), but did not activate the expression of sugar up-regulated genes (Ho et al. 2001). Sugarstarved sycamore cells incubated in the presence of Glyc or pyruvate stopped growing but were able to survive for weeks in the absence of any gluconeogenesis and did not display autophagy symptoms (Aubert ...
The main theoretical questions
... Topic 3.9. Steroid hormones of sex glands. Endocrine control of metabolism in the well-fed state. Regulation of metabolism in starvation. Topic 3.10. Interrelation and regulation of all metabolism pathways. Content module 8 “Biochemistry and pathobiochemistry of the Blood” Topic 3.11. Investigation ...
... Topic 3.9. Steroid hormones of sex glands. Endocrine control of metabolism in the well-fed state. Regulation of metabolism in starvation. Topic 3.10. Interrelation and regulation of all metabolism pathways. Content module 8 “Biochemistry and pathobiochemistry of the Blood” Topic 3.11. Investigation ...
soy protein concentrate - US Soybean Export Council
... selected and cleaned as the first step in soy product processing. The clean soybeans are dehulled, then the oil is extracted for cooking, biodiesel and other uses. The residue, consisting of defatted white flakes, can then be ground to make soy flour, toasted and ground to make soybean meal, or subj ...
... selected and cleaned as the first step in soy product processing. The clean soybeans are dehulled, then the oil is extracted for cooking, biodiesel and other uses. The residue, consisting of defatted white flakes, can then be ground to make soy flour, toasted and ground to make soybean meal, or subj ...
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... decades, such as physical, chemical, sftain, molecular biology, and immunological characteristics. Some investigators revealed the topologicalforms ofprionprotein in the endoplasmic reticulum membrane and theirrole inthe pathophysiologicalprocess of the disease. But still prion diseases continue 1o ...
... decades, such as physical, chemical, sftain, molecular biology, and immunological characteristics. Some investigators revealed the topologicalforms ofprionprotein in the endoplasmic reticulum membrane and theirrole inthe pathophysiologicalprocess of the disease. But still prion diseases continue 1o ...
Sequences beyond the Cleavage Site Influence Signal Peptide
... with the signal could be studied by using precise mutagenesis of both signal and passenger coding regions. recognition particle and with anothercomponentof Recent work using similarly constructed fusion proteins the translocation system, signal peptidase, were observed. Our results suggest that subt ...
... with the signal could be studied by using precise mutagenesis of both signal and passenger coding regions. recognition particle and with anothercomponentof Recent work using similarly constructed fusion proteins the translocation system, signal peptidase, were observed. Our results suggest that subt ...
Impact of Ischemia on Cellular Metabolism
... ergy for many metabolic and biochemical reactions involved in development, adaptation and cell survival. ATP production in an aerobic cell is particularly effective when the degra‐ dation of key nutrients such as glucose and fatty acids is coupled to a supramolecular com‐ plex located in the inner m ...
... ergy for many metabolic and biochemical reactions involved in development, adaptation and cell survival. ATP production in an aerobic cell is particularly effective when the degra‐ dation of key nutrients such as glucose and fatty acids is coupled to a supramolecular com‐ plex located in the inner m ...
B vitamins
... Strauss, M. B. (1938, March 26). THE THERAPEUTIC USE OF VITAMIN B, IN POLYNEURITIS AND CARDIOVASCULAR CONDITIONS. The Journal of American Medical Association, 110(13), 953-956. doi:10.1001/jama.1938.62790130003006 Vitamin B9 (Folic acid). (n.d.). Retrieved September 26, 2016, from http://umm.edu/hea ...
... Strauss, M. B. (1938, March 26). THE THERAPEUTIC USE OF VITAMIN B, IN POLYNEURITIS AND CARDIOVASCULAR CONDITIONS. The Journal of American Medical Association, 110(13), 953-956. doi:10.1001/jama.1938.62790130003006 Vitamin B9 (Folic acid). (n.d.). Retrieved September 26, 2016, from http://umm.edu/hea ...
A prophage-encoded actin-like protein required for efficient viral
... virion assembly and lysis of the host cell (3,4). Recent reports revealed that viral replication in prokaryotes appears to be organized at specific intracellular locations and this process relies on the action of cytoskeletal proteins (5). Cytoskeletal elements in eu- and prokaryotes are involved in ...
... virion assembly and lysis of the host cell (3,4). Recent reports revealed that viral replication in prokaryotes appears to be organized at specific intracellular locations and this process relies on the action of cytoskeletal proteins (5). Cytoskeletal elements in eu- and prokaryotes are involved in ...
The Complement of Protein Phosphatase
... evolutionary ancestry. These clusters, particularly for the largely unexplored PP2C set, will be a rich source of material for plant biologists, allowing the systematic sampling of protein function by genetic and biochemical means. ...
... evolutionary ancestry. These clusters, particularly for the largely unexplored PP2C set, will be a rich source of material for plant biologists, allowing the systematic sampling of protein function by genetic and biochemical means. ...
Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.