Kinetic analysis of retroviral proteases by HELGA EIZERT
... transcriptase to copy virion genomic RNA into proviral DNA, which is integrated into the infected host cell genome. Thus, there is a reverse flow of information from RNA to DNA during the virus life cycle (hence “retro” for backwards). Retroviral virions measure approximately 80-100 nm in diameter. ...
... transcriptase to copy virion genomic RNA into proviral DNA, which is integrated into the infected host cell genome. Thus, there is a reverse flow of information from RNA to DNA during the virus life cycle (hence “retro” for backwards). Retroviral virions measure approximately 80-100 nm in diameter. ...
AP Biology Fall Final Review
... Use the information given here to answer the following questions. Feather color in budgies is determined by two different genes that affect the pigmentation of the outer feather and its core. Y_B_ is green; yyB_ is blue; Y_bb is yellow; and yybb is white. 49. Two blue budgies were crossed. Over the ...
... Use the information given here to answer the following questions. Feather color in budgies is determined by two different genes that affect the pigmentation of the outer feather and its core. Y_B_ is green; yyB_ is blue; Y_bb is yellow; and yybb is white. 49. Two blue budgies were crossed. Over the ...
Alfred G. Gilman - Nobel Lecture
... toxin to ADP-ribosylate Gs was lost. This could be restored by addition of a protein factor {33} that was eventually purified, named ADP-ribosylation factor or ARF, and found to be a low-molecular-weight GTP binding protein (34, 35). ARF is, of course, now leading a happy existence as an important r ...
... toxin to ADP-ribosylate Gs was lost. This could be restored by addition of a protein factor {33} that was eventually purified, named ADP-ribosylation factor or ARF, and found to be a low-molecular-weight GTP binding protein (34, 35). ARF is, of course, now leading a happy existence as an important r ...
Johansson L, Gafvelin G, Arnér ES. Selenocysteine in proteins
... DTT can play this role. However, it is possible that the thioredoxin system involving the selenoprotein thioredoxin reductase could act as a cofactor, at least for D1 [17]. With different reaction mechanisms, the Sec residue has clearly different roles in the reactions catalyzed by D1 as compared to ...
... DTT can play this role. However, it is possible that the thioredoxin system involving the selenoprotein thioredoxin reductase could act as a cofactor, at least for D1 [17]. With different reaction mechanisms, the Sec residue has clearly different roles in the reactions catalyzed by D1 as compared to ...
Non-homologous Recombination of Deoxyribonucleoside Kinases
... in the homology model appears to disrupt α4 and β3. The third crossover introduces a point mutation (S170A, DmdNK numbering) and extends the Lid by insertion of 2 aa between α7 and α8. In HDHD12 there is no insertion or deletion at the second crossover. The third crossover occurs after the Lid regio ...
... in the homology model appears to disrupt α4 and β3. The third crossover introduces a point mutation (S170A, DmdNK numbering) and extends the Lid by insertion of 2 aa between α7 and α8. In HDHD12 there is no insertion or deletion at the second crossover. The third crossover occurs after the Lid regio ...
Modulation of the Antigenic Peptide Transporter TAP by
... peptide derived of TAP1 or TAP2 is recognized. The same results were obtained in mapping experiments on peptide arrays with one amino acid off-set (data not shown). To determine the precise epitope and critical residues for epitope recognition, systematically permutated variants and arrays of N and ...
... peptide derived of TAP1 or TAP2 is recognized. The same results were obtained in mapping experiments on peptide arrays with one amino acid off-set (data not shown). To determine the precise epitope and critical residues for epitope recognition, systematically permutated variants and arrays of N and ...
The Computational Complexity of Protein
... Proteins play key roles in many cellular functions. Fibrous proteins are found in hair, skin, bone, and blood. Membrane proteins are found in cells’ membranes, where they mediate the exchange of molecules and information across cellular boundaries. Water-soluble globular proteins serve as enzymes th ...
... Proteins play key roles in many cellular functions. Fibrous proteins are found in hair, skin, bone, and blood. Membrane proteins are found in cells’ membranes, where they mediate the exchange of molecules and information across cellular boundaries. Water-soluble globular proteins serve as enzymes th ...
Carbon isotope analysis of bulk keratin and single amino acids from
... your body is formed originates in the diet.1–4 During life almost all human and animal body tissues are in a state of breakdown and re-synthesis, incorporating molecules from the diet on a continual basis.5 Stable isotopic measurements of body tissues such as bone collagen, which often survives inta ...
... your body is formed originates in the diet.1–4 During life almost all human and animal body tissues are in a state of breakdown and re-synthesis, incorporating molecules from the diet on a continual basis.5 Stable isotopic measurements of body tissues such as bone collagen, which often survives inta ...
LatFit - Manual - Bioinformatics Group Freiburg
... is performed. A direction vector is given by d~ = k · (pdbAtom − Cα ), whereby k is a calculated scaling factor to set the length of d~ to dirVecLength. -dirVecLength The length of the direction vector to fit, if -fitDirVec is specified. ...
... is performed. A direction vector is given by d~ = k · (pdbAtom − Cα ), whereby k is a calculated scaling factor to set the length of d~ to dirVecLength. -dirVecLength The length of the direction vector to fit, if -fitDirVec is specified. ...
PPT
... Secondary Structure Prediction Servers Prediction Evaluation? • Q3 score - % of residues correctly predicted (3-state) in cross-validation experiments ...
... Secondary Structure Prediction Servers Prediction Evaluation? • Q3 score - % of residues correctly predicted (3-state) in cross-validation experiments ...
B7 Enzymes
... structures where all the charged (hydrophilic and hydrophobic) amino acids residues are paired. Many enzymes are absolutely specific for a particular substrate (not even an enantiomer), where others will react with a whole class of molecules but at widely different rates. ...
... structures where all the charged (hydrophilic and hydrophobic) amino acids residues are paired. Many enzymes are absolutely specific for a particular substrate (not even an enantiomer), where others will react with a whole class of molecules but at widely different rates. ...
406 PRELIMINARY NOTES Formation of lysophosphatidyl
... of both I- and a-acyl lyso-PE, basically in agreement with the findings of VAN DEN BOSCH”. The nuclear fraction also catalyzed the hydrolysis of both fatty acids from the PE as shown by the accumuIation of both lysoisomers. This fraction also contained an active lysophospholipase activity as indicat ...
... of both I- and a-acyl lyso-PE, basically in agreement with the findings of VAN DEN BOSCH”. The nuclear fraction also catalyzed the hydrolysis of both fatty acids from the PE as shown by the accumuIation of both lysoisomers. This fraction also contained an active lysophospholipase activity as indicat ...
BIOCHEMISTRY
... Hydrocarbons $30 What is the removing of water to join monomers called? What is the addition of water to split polymers called? Dehydration synthesis Hydrolysis Cinda Sheldon ...
... Hydrocarbons $30 What is the removing of water to join monomers called? What is the addition of water to split polymers called? Dehydration synthesis Hydrolysis Cinda Sheldon ...
An LL-Diaminopimelate Aminotransferase
... LL-DAP-AT activity. None of the other genes produced such an activity. At4g33680 was annotated as a 461-amino acid, class I/II family aminotransferase. The first 36 amino acids were predicted by TargetP to be a transit peptide for localization of the protein to plastids. The closest paralog to At4g3 ...
... LL-DAP-AT activity. None of the other genes produced such an activity. At4g33680 was annotated as a 461-amino acid, class I/II family aminotransferase. The first 36 amino acids were predicted by TargetP to be a transit peptide for localization of the protein to plastids. The closest paralog to At4g3 ...
Specific amino acids in the BAR domain allow homodimerization
... allowed the mutant SNX9 to heterodimerize with SNX33. Taken together, the present study identifies critical amino acids within the BAR domains of SNX9 and SNX33 as determinants for the specificity of BAR domain-mediated interactions and suggests that SNX9 and SNX33 have distinct molecular functions. ...
... allowed the mutant SNX9 to heterodimerize with SNX33. Taken together, the present study identifies critical amino acids within the BAR domains of SNX9 and SNX33 as determinants for the specificity of BAR domain-mediated interactions and suggests that SNX9 and SNX33 have distinct molecular functions. ...
Introduction to Protein Structure
... • Active conformation of protein is the native state • unfolded, denatured state – high temperature – high pressure – high concentrations urea (8 M) • Equilibrium between two forms ...
... • Active conformation of protein is the native state • unfolded, denatured state – high temperature – high pressure – high concentrations urea (8 M) • Equilibrium between two forms ...
scf and cullin/ring h2-based
... Identification of the SCFCdc4 ubiquitin ligase complex stemmed from a genetic analysis of the G1/S transition by Schwob et al (1994). These authors demonstrated that budding yeast cdc4ts, cdc34ts, and cdc53ts mutants fail to enter S phase because they are unable to eliminate the S phase cyclin/cycli ...
... Identification of the SCFCdc4 ubiquitin ligase complex stemmed from a genetic analysis of the G1/S transition by Schwob et al (1994). These authors demonstrated that budding yeast cdc4ts, cdc34ts, and cdc53ts mutants fail to enter S phase because they are unable to eliminate the S phase cyclin/cycli ...
Symbolic Systems Biology
... About Pathway Logic Pathway Logic (PL) is an approach to modeling biological processes as executable formal specifications (in Maude) The resulting models can be queried using formal methods tools: given an initial state execute --- find some pathway search --- find all reachable states satisfying ...
... About Pathway Logic Pathway Logic (PL) is an approach to modeling biological processes as executable formal specifications (in Maude) The resulting models can be queried using formal methods tools: given an initial state execute --- find some pathway search --- find all reachable states satisfying ...
Powerpoint slides
... a common ancestor (i.e. they are homologous). • … or, perhaps two proteins may be similar because they perform similar functions and are thereby constrained, even though they arose independently (functional convergence hypothesis, they are then called analogous). ...
... a common ancestor (i.e. they are homologous). • … or, perhaps two proteins may be similar because they perform similar functions and are thereby constrained, even though they arose independently (functional convergence hypothesis, they are then called analogous). ...
Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.