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Brain-Derived Neurotrophic Factor mRNA Expression in the Brain of the Teleost
Brain-Derived Neurotrophic Factor mRNA Expression in the Brain of the Teleost

... ing development in regulating neuronal survival, promoting axonal pathfinding and elongation towards targets, and in supporting synaptic plasticity [McAllister et al., 1999; Huang and Reichardt, 2001; Gillespie, 2003; Cohen-Cory and Lom, 2004] and is involved in neuronal © Free Author Copy – for per ...
Single nucleotide polymorphism in the neuroplastin locus
Single nucleotide polymorphism in the neuroplastin locus

... Twin studies have demonstrated that brain structure is under significant genetic influence,7 with cortical thickness showing high heritability in children1,8 and adults.9,10 Differences in heritability are nonetheless notable. First, comparison of estimates of genetic effects in the left and right hem ...
Fractalkine is a “find-me” signal released by neurons
Fractalkine is a “find-me” signal released by neurons

... debris in fractalkine-knockout (KO) and CX3CR1-KO mice following ethanol treatment revealed increased apoptotic bodies compared to wild type mice. Ethanol-induced injury led to release of soluble, extracellular fractalkine. The extracellular media harvested from apoptotic brains induces microglial m ...
Optogenetic Brain Interfaces
Optogenetic Brain Interfaces

... Optogenetics applies light-sensitive proteins which have been isolated from various microorganisms and plants, to manipulate excitable cells in heterologous systems. Initial work in the field used naturally occurring photosensitive proteins such as channelrhodopsin (ChR) [6] and halorhodopsin (HR) [ ...
PDF hosted at the Radboud Repository of the Radboud University Nijmegen
PDF hosted at the Radboud Repository of the Radboud University Nijmegen

... the morphological, physiological and biochemical features of neurons, and enormous efforts are being devoted to tracing their functional properties down to the level of individual molecules. However, despite the victorious career of this analytic approach we are still lacking an appropriate under­ s ...
Brain, Mood and Cognition in Hypothyroidism
Brain, Mood and Cognition in Hypothyroidism

... subclinically reduced mood in long-term adequately treated patients, but the mood alterations were not associated with alterations in depression-related brain networks. We identified thyroid autoimmunity and treatment duration as factors of neural alterations in long-term treated hypothyroidism. In ...
Neural Correlates of Learning in the Prefrontal Cortex of the Monkey
Neural Correlates of Learning in the Prefrontal Cortex of the Monkey

... In agreement with experimental data, two main types of activity contribute to the adaptive properties of the network. The first is transient activity time-locked to events of the task and its profile remains constant during successive training stages. The second is sustained activity that undergoes ...
Neurons in the corpus callosum of the cat during postnatal
Neurons in the corpus callosum of the cat during postnatal

... boundaries of the CC, and in the adult to the rostrum of the CC close to the septum pellucidum or to the indusium griseum. Although origin and function of transient CC neurons in development and in adulthood remain unknown, they are likely to be interstitial neurons. Some of them have well-developed ...
child development - Goodheart
child development - Goodheart

... Basic Wiring • Neurons are brain cells that direct various tasks of the brain • Wiring is a network of fibers that carry signals between neurons • Axons are cables that transmit signals from a neuron to other neurons ...
Association of type I neurons positive for NADPH
Association of type I neurons positive for NADPH

... Positive neurons were densely filled, in Golgi-like detail, and therefore unambiguously classified as type 1 (Yan et al., 1996; Estrada and DeFelipe, 1998). No examples of type 2 neurons, defined as small, lightly stained neurons, were evident. Within the broad category of type 1, however, further subp ...
Developing an Effective Parenting Style
Developing an Effective Parenting Style

... Basic Wiring • Neurons are brain cells that direct various tasks of the brain • Wiring is a network of fibers that carry signals between neurons • Axons are cables that transmit signals from a neuron to other neurons ...
Fat Embolism - IMA Pathankot
Fat Embolism - IMA Pathankot

... with Agglutination. ...
American Journal of Public Health Research
American Journal of Public Health Research

... gland and initiates a heavily regulated stress response pathway (O Connor et al., 2000). Amygdala which is situated bilaterally deep within the medial temporal lobes of the brain play vital roles in the processing of emotions by modulating stress response mechanisms particularly when feelings of anx ...
Methamphetamine Users in Sustained Abstinence
Methamphetamine Users in Sustained Abstinence

... cover with prolonged abstinence.16,20-25 A series of positron emission tomography studies have tracked neuronal changes as a function of methamphetamine abstinence in human methamphetamine users. In 1 of the first positron emission tomography studies, McCann et al21 reported striatal dopamine trans ...
MRM spectrscopy
MRM spectrscopy

... ents act to alter the magnetic field along the direction they are applied. A gradient along the z axis causes the field to vary along that axis. Application of a narrow radio frequency pulse at 64 MHz in the presence of this strong gradient excites only those protons in a very narrow slice, which sa ...
Neuronal networks for induced `40 Hz` rhythms
Neuronal networks for induced `40 Hz` rhythms

... of the brain have the intrinsic capacity to oscillate at about 40 Hz. Space does not permit an exhaustive reviewof intrinsic oscillators;here we outline one or two relevant cases. For example, severaltypes of neurones in the thaiamocortical system such as the reticular34 and intralaminar35neurones d ...
Distribution and characterisation of Glucagon-like peptide
Distribution and characterisation of Glucagon-like peptide

... Figure 1: GLP-1 receptor expressing cells in the CNS. A, B. Demonstrates the reporter expression in the dorsal vagal complex of the eYFP and tdRFP mice. Expression was equivalent in the area postrema (AP), nucleus tractus solitarius (NTS) and dorsal motor nucleus of the vagus (DMV). High levels of r ...
Role of Nitric Oxide on Dopamine Release and Morphine
Role of Nitric Oxide on Dopamine Release and Morphine

... but increases sensitivity of DA release, and increased DA release at high frequencies can be due to nAChR desensitization (Zhang & Sulzer, 2004). The second mechanism of NO appears to be directly related to DA axons, and also increases evoked DA regardless of the stimulus frequency. Mechanistically, ...
Confirmation, Falsification, and Fallibility
Confirmation, Falsification, and Fallibility

... needed to make the prediction are true AND if the experimental setup is adequate, then the prediction will be true The prediction is not true ∴The hypothesis is false, OR an auxiliary hypothesis is false, OR the experimental setup is not adequate. Challenge: When to reject one of the auxiliary hypot ...
Neurogenesis from Neural Stem Cells, Ependymal Cells and
Neurogenesis from Neural Stem Cells, Ependymal Cells and

... Stroke is a major cause of death and disability around the world. Stroke leads to loss of neurons and also other cells in the brain due to lack of blood supply. Currently no therapies are available to treat stroke-related disability. It has been shown that stroke leads to increased neurogenesis, bir ...
Full Text
Full Text

... with spheroids HDLS are two adult onset leukodystrophies with neuroaxonal spheroids presenting with prominent neurobehavioral, cognitive, and motor symptoms. These are familial or sporadic disorders characterized by cerebral white matter degeneration including myelin and axonal loss, gliosis, macrop ...
- The Wonderful Hormone - INSULIN - UCO
- The Wonderful Hormone - INSULIN - UCO

... genetically altered bacteria was approved for use with insulin dependent patient – This form of insulin is an exact match to that which is made in the body ...
RAAS Basic physiology and Pathophysiolgy
RAAS Basic physiology and Pathophysiolgy

... glands), remaining 10% is found in soluble form in the interstium of vessel wall.  Where they have not only endocrine but also paracrine and autocrine effects. ...
the spinal cord and the influence of its damage on
the spinal cord and the influence of its damage on

... In the healthy spinal cord, many axons secrete minute amounts of the neurotransmitter glutamate at their synapses. When this chemical binds to its receptors on target neurons, it stimulates those cells to fire impulses. But when spinal neurons, axons, or astrocytes are injured, they release a flood ...
Midbrain fMRI: Applications, Limitations and Challenges
Midbrain fMRI: Applications, Limitations and Challenges

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Haemodynamic response



In haemodynamics, the body must respond to physical activities, external temperature, and other factors by homeostatically adjusting its blood flow to deliver nutrients such as oxygen and glucose to stressed tissues and allow them to function. Haemodynamic response (HR) allows the rapid delivery of blood to active neuronal tissues. Since higher processes in the brain occur almost constantly, cerebral blood flow is essential for the maintenance of neurons, astrocytes, and other cells of the brain.
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