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History of Genetics
History of Genetics

... • 1972: Stanley Cohen and Herbert Boyer combine DNA from two different species in vitro, then transform it into bacterial cells: first DNA cloning. • 2001: Sequence of the entire human genome is announced. ...
From Mendel to Human Genome
From Mendel to Human Genome

... In the early __________, proceeded to study __________. The ratio of G:C was __________ and the ratio of T:A was __________, with evidence that the long molecule might be wound up in a _______________. Discovered crystallography structured data for DNA. ...
Cytosine – ______ Sugar
Cytosine – ______ Sugar

... 2. Draw a guanine nucleotide based on Figure 12-5. Label each part of the nucleotide. ...
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

... 21. (a) Explain the molecular mechanisms involved in the repair of oxidative DNA damage. OR b) Discuss the role of telomerase in aging. 22. (a) What are the clinical features of human mitochondrial DNA mutations in adults? OR (b) Explain genome imprinting and Angelman syndrome. 23. (a) Enumerate the ...
History of Genetics
History of Genetics

... GENE -part of a DNA molecule • ________ that determines the inherited trait. • Chromosome ____________ - condensed DNA, acts as a storage unit. ...
Greatest Discoveries with Bill Nye: Genetics
Greatest Discoveries with Bill Nye: Genetics

... 12. What did Morgan and his students show that is important to modern genetics? Genes control Biochemical Events 13. What organism did Beadle and Tatum use for their experiments? 14. What did Beadle and Tatum do to this organisms to produce genetic changes? 15. What changes did this process cause to ...
19 extranuclear inheritance
19 extranuclear inheritance

... 2. The Mitochondrial Eve Hypothesis proposes that all human mitochondrial genomes evolved from a “single” original genome approximately 200,000 years ago. The human mitochondrial genome is maternally inherited. Therefore, the original genome must have been present in the first Homo sapiens female—he ...
History of Genetics
History of Genetics

... • 1972: Stanley Cohen and Herbert Boyer combine DNA from two different species in vitro, then transform it into bacterial cells: first DNA cloning. • 2001: Sequence of the entire human genome is announced. ...
History of Genetics - NIU Department of Biological Sciences
History of Genetics - NIU Department of Biological Sciences

... • 1972: Stanley Cohen and Herbert Boyer combine DNA from two different species in vitro, then transform it into bacterial cells: first DNA cloning. • 2001: Sequence of the entire human genome is announced. ...
Study Guide for LS
Study Guide for LS

...  Insertion is when an extra base is added into the sequence.  Deletion is when a base is deleted from the sequence.  Substitution is when one base is substituted for another. A mutation in DNA could result in no change, death or a genetic disorder. A mutagen is something that causes mutations. (E ...
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Test review Warm-up

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Mutations Can Change the Meaning of Genes
Mutations Can Change the Meaning of Genes

... How Mutations Affect Genes Mutation: any change in the nucleotide sequence of DNA  Types of Mutations:  Base substitutions: replacement of one nucleotide w/ another. May or may not affect protein  Base deletions & Base insertions:  May be more harmful b/c all subsequent codons will be altered ...
Isogamous, hermaphroditic inheritance of mitochondrion
Isogamous, hermaphroditic inheritance of mitochondrion

... (Pm2), Armada (Pm4b), and Holger (Pm6). Ó 2002 Elsevier Science (USA). All rights reserved. ...
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DATA QUALITY SHEET 1 kb DNA Ladder no stain

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REPLICATION, TRANSCRIPTION, TRANSLATION TAKS
REPLICATION, TRANSCRIPTION, TRANSLATION TAKS

... 14 Part of a DNA strand is represented in the diagram above. In order for DNA to replicate, the strand must separate at which of the following locations? F Between every phosphate-sugar pair G Between the eight sugar-base pairs H* Between the four nitrogenous base pairs J Between any two chemical bo ...
Bononformatics
Bononformatics

... The difficult part was in figuring out which parts of the DNA strand were genes that had a specified outcome in the final human created by the genetic program. Much of the DNA strand is made up of junk material that serves no actual purpose, which makes figuring it out all the more difficult. Comput ...
Genetics and Health
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Chapter 16: The Molecular Basis of Inheritance
Chapter 16: The Molecular Basis of Inheritance

... 12. What are the functions of primase? DNA polymerase? Ligase? 13. What is the difference between the 5’ and 3’ ends of the DNA molecule? Where are the 5’ and 3’ ends on opposite strands of the double helix? 14. What is the difference between the leading and lagging strand during replication? Why ar ...
AZBio Ch 13
AZBio Ch 13

... During transformation, a cell takes in DNA from outside the cell, and becomes part of the cell’s DNA. The foreign DNA is first joined to a small, circular DNA known as a plasmid. Plasmids are found naturally in some bacteria and have been very useful for DNA transfer. Why? The plasmid has a genetic ...
Introduction to Agriculture, Food, and Natural Resources
Introduction to Agriculture, Food, and Natural Resources

... follows: • Cytosine (C) combines with Guanine (G) • Adenine (A) combines with Thymine (T) ...
 
 

... A key event in eukaryotic evolution, the symbiotic introduction of mitochondria (mt), occurred a billion or more  years ago. This symbiosis contributed roughly 1/10th the genetic material to extant eukaryotes, which apparently  all have or once had a mitochondrion. Most genes of mt origin are no lon ...
The modern synthesis
The modern synthesis

... One of the key assumptions of the theory of natural selection. How does that work? Genes! ...
Cytoplasmic inheritance
Cytoplasmic inheritance

... 5. ORFs (open reading frames) sequences capable of encoding proteins but no product has been identified ...
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Mitochondrial DNA



Mitochondrial DNA (mtDNA or mDNA) is the DNA located in mitochondria, cellular organelles within eukaryotic cells that convert chemical energy from food into a form that cells can use, adenosine triphosphate (ATP). Mitochondrial DNA is only a small portion of the DNA in a eukaryotic cell; most of the DNA can be found in the cell nucleus and, in plants, in the chloroplast.In humans, mitochondrial DNA can be assessed as the smallest chromosome coding for 37 genes and containing approximately 16,600 base pairs. Human mitochondrial DNA was the first significant part of the human genome to be sequenced. In most species, including humans, mtDNA is inherited solely from the mother.The DNA sequence of mtDNA has been determined from a large number of organisms and individuals (including some organisms that are extinct), and the comparison of those DNA sequences represents a mainstay of phylogenetics, in that it allows biologists to elucidate the evolutionary relationships among species. It also permits an examination of the relatedness of populations, and so has become important in anthropology and field biology.
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