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Eradicating infectious disease using weakly transmissible vaccines
Eradicating infectious disease using weakly transmissible vaccines

... deployed in wild animal populations [6]. For instance, recombinant transmissible vaccines have been developed to protect wild rabbit populations against myxomatosis [9] and to interrupt the transmission of Sin Nombre hantavirus in reservoir populations of deer mice [10,11]. In addition, a transmissi ...
Novel antibody binding determinants on the capsid surface of
Novel antibody binding determinants on the capsid surface of

... Five neutralizing antigenic sites have been described for serotype O foot-and-mouth disease viruses (FMDV) based on monoclonal antibody (mAb) escape mutant studies. However, a mutant virus selected to escape neutralization of mAb binding at all five sites was previously shown to confer complete cros ...
Sequence-Based Identification of Microbial Pathogens
Sequence-Based Identification of Microbial Pathogens

... The limitations of Koch’s postulates, evident in the 1800s, are even more pronounced today. Organisms such as Plasmodium falciparum and herpes simplex virus or other viruses cannot be grown alone, i.e., in cell-free culture, and hence cannot fulfill Koch’s postulates, yet they are unequivocally path ...
Exotic disease focus: Chronic wasting disease
Exotic disease focus: Chronic wasting disease

... Transmission is known to occur naturally within species, from elk to mule deer and white-tailed deer, from mule deer to elk, and from mule deer to white-tailed deer. It is also known that transmission of CWD can occur between farmed and feral populations, most ...
Here
Here

... model for the job is a trade-off between simplicity, accuracy and generality. An inaccurate model is no good to anyone, we need a model that approximates what’s going on in the real world. A complex model might be more accurate (in general), but it may be too complex to understand or parameterise. F ...
pntd-10-8-Phu Huong Lan
pntd-10-8-Phu Huong Lan

... for every patient. Clinical data recorded on admission included sex, HIV status (HIV diagnosed according to the World Health Organization (WHO) guidelines [21]), axillary temperature, presence of co-infection and hospital outcome. Outcome was classified based on clinician notes as follows: (1) recov ...
Cost of Measles Containment in an Ambulatory
Cost of Measles Containment in an Ambulatory

... the US is imperative to prevent outbreaks. Economic analyses of measles exposures have included containment costs incurred by hospitals caring for patients with measles8 and costs incurred by public health departments9,10 in investigating cases and controlling further spread. Other studies have focu ...
Sore Throats - Central Park ENT
Sore Throats - Central Park ENT

... develop his immunities (antibodies). Healthy tonsils do not remain infected. Frequent sore throats from tonsillitis suggest the infection is not fully eliminated between episodes. A medical study has shown that children who suffer from frequent episodes of tonsillitis (such as three-to four- times ...
Human Parvovirus B19
Human Parvovirus B19

... animal parvoviruses in gel diffusion – all neg. Finally we tested the sera of all the lab staff -40% positive so B19 was a common human infection. Then we published – but B19 was still an “orphan” with no known disease association – and nothing we did enabled us to culture it. So in 1977 all our sam ...
HIV/AIDS DOES IT MATTER TO A UTAH PEDIATRICIAN ?
HIV/AIDS DOES IT MATTER TO A UTAH PEDIATRICIAN ?

... aging HIV epidemic • The emphasis will be on the epidemic in the First World – Overview of history of the epidemic as it ages – Review the aging epidemiology – Review how age affects the disease process ...
Case Study Number Two • SW is a 72 year old female who presents
Case Study Number Two • SW is a 72 year old female who presents

... Case Study Number Two ...
Effects of Infectious Bursal Disease Vaccination Strains on the
Effects of Infectious Bursal Disease Vaccination Strains on the

... antibodies tests was considered sufficient in view of their parents’ negative IBDV antibodies titres. The remaining 40 chickens were equally divided into a test group and a control group, i.e. each group consisted of 20 chickens. Vaccines were administered in drinking water according to manufacturer ...
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PDF

... paradoxical response often subsides spontaneously while the patient is kept on antituberculosis treatment and this might explain the reversible nature of high-grade AV block in this patient. However, the hypothesis can only be approved if serial endomyocardial biopsy was done, which has been decline ...
B Notifications - Curry International Tuberculosis Center
B Notifications - Curry International Tuberculosis Center

... B notifications are sent by the Centers for Disease Control and Prevention (CDC) to the <> Tuberculosis (TB) Program as follow-up to the screening mandated by United States immigration law. The purpose of mandated screening is to deny entry to persons who have either communicable disease ...
natural and experimental west nile virus infection in five
natural and experimental west nile virus infection in five

... mortality in people, horses, and hundreds of bird species (Komar, 2003). Avian disease due to WNV infections is a novel phenomenon; before 1998 natural occurrence had only been reported in two instances, each affecting a single bird (Work et al., 1953; Burt et al., 2002). The extent of morbidity and ...
Get cached
Get cached

... ration, feeding more of it will do no good. Money can be saved, for example, by feeding the first mixture mentioned above, which is less expensive than the second, i£ only calcium is needed. For further in­ formation see R ef erenc es 1 and 13, pages 46 and 47. ...
CCG mission, aim and values Presentation to staff Monday 10
CCG mission, aim and values Presentation to staff Monday 10

Differential diagnosis of Vertigo and Meneier`s Disease
Differential diagnosis of Vertigo and Meneier`s Disease

... Three eye movements assessed as part of the ENG are saccades, smooth pursuit, and optokinetic nystagmus. ...
Slide 1
Slide 1

... • Most countries will be able to perform some basic influenza identification tests on a clinical specimen, but more specific testing may need to be done at a higher level national or regional laboratory. • When you report on the progress of an outbreak investigation, share investigation results with ...
Policy 1.2 Diagnosis of tuberculosis– Clinical (PDF 401KB)
Policy 1.2 Diagnosis of tuberculosis– Clinical (PDF 401KB)

... for the test to be reliably positive and is not specific for Mycobacterium tuberculosis. On the other hand, culture is the most sensitive method for diagnosis, but may take 2-4 weeks to yield a positive result. Microscopy and culture for tuberculosis however, remains the first line tests for TB dete ...
Teacher`s Resource Kit
Teacher`s Resource Kit

... Include the work of Fleming, Pasteur, Koch, miasma theory, germ theory, McFarland Burnett, the manufacture of the first antibiotics on a mass scale, etc. Include the World Wars and major epidemics such as Smallpox, Bubonic Plague, and Spanish Influenza. ...
Risks of spreading foot and mouth disease through milk and
Risks of spreading foot and mouth disease through milk and

... d) the filling of the tanker with milk will result in the displacement of air from the tanker. Agitation w i t h i n the tanker during filling and transportation could then result in the release of infective aerosols. Epidemiological links were found between the routes taken by bulk milk tankers and ...
Science - Princeton University
Science - Princeton University

... Reductions in nonmeasles infectious disease mortality (SM 1) are shown in Fig. 1, for children aged 1 to 9 years in Europe and aged 1 to 14 years in the United States, shortly after the onset of mass vaccination in each country. The fall in mortality was later in Denmark, corresponding to the introd ...
Furtive foes: algal viruses as potential invaders
Furtive foes: algal viruses as potential invaders

... suitable host population because they cannot reproduce outside their host. The geographical range of potential host algae and the host range of the introduced virus are important for assessing the potential for invasion success. Theoretically, without considering any biases introduced by the mode of ...
Generalized Lymphadenopathy: A Case Report of Rosai
Generalized Lymphadenopathy: A Case Report of Rosai

... Received: 3 Jun 2007 Accepted:4 July 2007 ...
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Pandemic



A pandemic (from Greek πᾶν pan ""all"" and δῆμος demos ""people"") is an epidemic of infectious disease that has spread through human populations across a large region; for instance multiple continents, or even worldwide. A widespread endemic disease that is stable in terms of how many people are getting sick from it is not a pandemic. Further, flu pandemics generally exclude recurrences of seasonal flu. Throughout history there have been a number of pandemics, such as smallpox and tuberculosis. More recent pandemics include the HIV pandemic as well as the 1918 and 2009 H1N1 pandemics. The Black Death was a devastating pandemic, killing over 75 million people.
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