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Peroxiredoxin-controlled G-CSF signalling at the endoplasmic
Peroxiredoxin-controlled G-CSF signalling at the endoplasmic

... of H2O2 for the so-called oxidative burst, a major weapon in host defence against bacteria. In non-phagocytic cells, H2O2 has long been considered as an unwanted by-product of cell metabolism, potentially hazardous because of the damaging effects on proteins, lipids, carbohydrates and nucleic acids ...
Biological Effects of Electromagnetic Fields
Biological Effects of Electromagnetic Fields

... radical pairs, and production of free radicals, such as reactive oxygen or nitric oxide, leading to further highly cooperative amplification step. Based on Frohlich's [1986] model of interactions between an imposed field and high-frequency (1012 Hz) intracellular van der Pol oscillators, they conclu ...
Biological Effects of Electromagnetic Fields
Biological Effects of Electromagnetic Fields

... radical pairs, and production of free radicals, such as reactive oxygen or nitric oxide, leading to further highly cooperative amplification step. Based on Frohlich's [1986] model of interactions between an imposed field and high-frequency (1012 Hz) intracellular van der Pol oscillators, they conclu ...
Animal Cell 3-Part Cards - Montessori for Learning
Animal Cell 3-Part Cards - Montessori for Learning

... 2. As an introductory lesson, students can match the correct picture to the control card and then find the label and description that matches the correct picture. *** Students can actually place the picture on top of the picture, description on top of the description and label on top of the label in ...
Cell division in magnetotactic bacteria splits magnetosome chain in
Cell division in magnetotactic bacteria splits magnetosome chain in

... with the protein MamJ [10, 11] and this ordinates and aligns the magnetosomes forming a cytoskeletal chain structure down the cell [9 – 11]. Although magnetotactic bacteria are the subject of increased research activity, there are still several basic questions that have not yet been fully answered. ...
Targeting Nitric Oxide Mediated Upregulation of Membrane
Targeting Nitric Oxide Mediated Upregulation of Membrane

... (Cetuximab, and Bevacizumab). Although the targets for therapeutic antibodies are diverse, they share several important characteristics in that they are expressed on tumor cells but not on healthy tissue, and are surface exposed to be easily targeted by the therapeutic antibody. The mechanism by whi ...
351 CHAPTER 21 Gram-Positive Cell Wall
351 CHAPTER 21 Gram-Positive Cell Wall

... The peptidoglycan sac derives its great mechanical strength from the fact that it is a single, covalently bonded structure. Most enzymes found in mammalian hosts and other biologic systems do not degrade peptidoglycan; one important exception is lysozyme, the hydrolase in tears and other secretions, ...
Cell Shapes
Cell Shapes

... – break down excess H2O2 with the enzyme catalase – break down fatty acids into acetyl groups ...
The Fusarium toxin Enniatin exerts p53
The Fusarium toxin Enniatin exerts p53

... HCT116 cells with p53, p21 or bax genes disrupted by targeted homologous recombination were used to study ENN-induced cytotoxicity. In MTT assays, no significant influences of these proteins were detected, resulting for all HCT116 subclones at IC50 values in the low µM range at a 72 h drug exposure. ...
Flow Cytometry - From Discovery to Clinical Analysis | Charles River
Flow Cytometry - From Discovery to Clinical Analysis | Charles River

... endpoint added to preclinical studies in order to assess the potential immunotoxicity effect of a drug. While changes in cell phenotypes are useful in some settings to characterize the immunotoxicity of different compounds, phenotypic analysis alone is often not a sensitive indicator of low-dose imm ...
PowerPoint-Präsentation - Biological Background I
PowerPoint-Präsentation - Biological Background I

... • Quantitative understanding of phytochrome B dynamics • Phenomenological model captures many features of phyB mediated photomorphogenesis • Physiology is most sensitive to changes in photoreceptor expression level • Excellent quantitative agreement between mesoscopic protein dynamics and macroscopi ...
Lipid-modified morphogens: functions of fats - treisman lab
Lipid-modified morphogens: functions of fats - treisman lab

... rafts [23]. However, the double bond in the palmitoleic acid introduces a kink in the acyl chain and would be expected to prevent inclusion in the ordered phase of the raft [23,33]. The opposing effects of the two acyl chains might thus allow for regulation of Wnt localization to rafts. Hh proteins ...
The DREAM Complex Mediates GIST Cell Quiescence and Is a
The DREAM Complex Mediates GIST Cell Quiescence and Is a

... 2. This process involves the DREAM complex as evidenced by upregulation of p130, increased p130/E2F4/LIN37 complex formation, and enhanced phosphorylation of the DREAM subunit LIN52. 3. Importantly, inhibition of DREAM complex formation, abrogation of quiescence by siRNA-mediated knock-down of LIN52 ...
Axon guidance and synaptic development
Axon guidance and synaptic development

a-Catulin, a Rho signalling component, can regulate NF
a-Catulin, a Rho signalling component, can regulate NF

Alleati per un`antropologia positiva Scienza e Vita in dialogo con AIOM
Alleati per un`antropologia positiva Scienza e Vita in dialogo con AIOM

Quarter Exam Study Guide Answer Key
Quarter Exam Study Guide Answer Key

... O They are found in the cell membrane. O A receptor is a protein that detects a signal ...
Dissecting the mechanisms of mTOR activation. Supervisor: Dr. Zita
Dissecting the mechanisms of mTOR activation. Supervisor: Dr. Zita

THE CELL model: Activity 4.1 – Science / Biology Objective: On a
THE CELL model: Activity 4.1 – Science / Biology Objective: On a

... 3-dimensional model of a cell (plant or **Models must be constructed of throwanimal) away items. Purchased models or items purchased for the purpose of model building will receive lower scores – Creativity is an expectation of this assignment ...
Bystin in human cancer cells: intracellular localization and function
Bystin in human cancer cells: intracellular localization and function

... fractionation identified bystin protein as nuclear and cytoplasmic, and immunofluorescence showed that nuclear bystin localizes mainly in the nucleolus. Sucrose gradient ultracentrifugation of total cytoplasmic ribosomes revealed preferential association of bystin with the 40S subunit fractions. To ...
Response - Dublin City Schools
Response - Dublin City Schools

Gene Therapy for Lung Cancer
Gene Therapy for Lung Cancer

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Insulin-Resistance, Browning

New type of drug-resistant isogenic cell model created by
New type of drug-resistant isogenic cell model created by

Unit 4 Test Review
Unit 4 Test Review

... nutrients and waste inside a cell *to ensure chemical reactions occur quickly and efficiently inside the cell ...
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SULF1

Sulfatase 1, also known as SULF1, is an enzyme which in humans is encoded by the SULF1 gene.Heparan sulfate proteoglycans (HSPGs) act as co-receptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endo-sulfatases, such as SULF1, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.
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