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A. Wu, D. Liao, T. Tlsty, J.C. Sturm, R.H. Austin, "Game theory in the death galaxy: interaction of cancer and stromal cells in tumour microenvironment", Interface Focus 4, 20140028 (JUN 2014).
A. Wu, D. Liao, T. Tlsty, J.C. Sturm, R.H. Austin, "Game theory in the death galaxy: interaction of cancer and stromal cells in tumour microenvironment", Interface Focus 4, 20140028 (JUN 2014).

... allowing cells to migrate through hexagons. The culture region and two supplying channels are separated by microslits (2.5 mm wide; figure 1b), so that cells are confined in the culture region, whereas nutrients and drug are able to diffuse in and form a linear drug gradient across the culture regio ...
The_Cell_Cylce_and_Hallmarks_of_Cancer
The_Cell_Cylce_and_Hallmarks_of_Cancer

... normal cells could replicate forever was overturned. Normal human and animal cells have a finite capacity to replicate and function whether they are cultured in vitro or transplanted as grafts in vivo. This phenomenon has been interpreted to be aging at the cellular level. Only abnormal somatic cell ...
Seminar Paper - LENS - The University of Auckland
Seminar Paper - LENS - The University of Auckland

... Earth has a total land area of 13,056 million hectares. World population experts estimate  that there are around 6 billon people  on the planet.  If this land resource was divided up  equally,  there  would  be  around  2.1  hectares  of  land  for  every  person  on  the  Earth.   However the world ...
BIO00011C Cell and Developmental Biology
BIO00011C Cell and Developmental Biology

... Module level learning outcome: Understanding the critical role that  differential gene (protein) expression plays in the life of eukaryotic cells  ...
T cell apoptosis and reactive oxygen species
T cell apoptosis and reactive oxygen species

... too short for production of ROS via increased mitochondrial activity (6). Thus, it may be that reactions that are more immediate than increased mitochondrial activity are responsible for at least the initial increases in ROS levels in activated T cells. A wellknown pathway for certain receptors to i ...
oncogenes
oncogenes

O TICS - Phi Optics
O TICS - Phi Optics

... Because of the large resolution of SLIM frames (e.g. 4 megapixels), large cell populations can be studied. SLIM was tested in cell growth measurements of mammalian cells over more than one cell cycle as shown in Figure 5 [2]. The results show that the mean cell mass evolves synchronously in time wit ...
Analysis of growth kinetics by division tracking
Analysis of growth kinetics by division tracking

... measured by sorting fluorescent beads from a single channel (fluorescein isothiocyanate beads for CFSE, phycoerythrin beads for PKH26) and reanalysing the sorted population. We have obtained best results using CFSE and a 10-channel sort window. Figure 1 shows the resolution of separate divisions usi ...
Key regulator of plant root growth identified
Key regulator of plant root growth identified

... “We discovered Nature’s way of controlling root hair growth. If you want root hair growth to occur you turn on RSL4; when you have had enough growth you turn it off” says Professor Liam Dolan the leader of the team that discovered RSL4. These data indicate that RSL4 is a master regulator of hair gro ...
Osmosis
Osmosis

... molecule that makes up most of the liquid part of the cytoplasm in living things. – Deals ONLY with the diffusion of WATER – The molecules (in this case, water - not solute molecules) will tend to move from an area of high (water) concentration to an area of low(water)concentration until equilibrium ...
Is It Made of Cells?
Is It Made of Cells?

... You get a sliver. This cell helps get rid of the wood now lodged in your finger. This cell is in the heart muscle of an Olympic sprinter. This cell is from a potato tuber. This cell is on the bottom of a nudibranch, a marine slug that moves around on a carpet of mucous. 5. This cell is from an organ ...
Project 1: Cells
Project 1: Cells

3rd WORKSHOP ON DENDRITIC CELL BIOLOGY
3rd WORKSHOP ON DENDRITIC CELL BIOLOGY

Preview Sample 1
Preview Sample 1

... Slides, transparencies, and electron micrographs are very useful for pointing out the major features of cells and organelles. These can be obtained from Carolina Biological Supply Company, Burlington, NC. Numerous WWW resources are also available such as http://www.cellbio.com. ...
Topics for Discussion The Extracellular Matrix
Topics for Discussion The Extracellular Matrix

... property of many proteins, that there are a number of functional domains. For example, the green colored dots represent collagen binding domains. Therefore, ECM molecules interact with other ECMs, and it is that interaction that will then contribute to the organization of these molecules within the ...
In This Issue - The Journal of Cell Biology
In This Issue - The Journal of Cell Biology

... to be revised because of a single research paper, but that appears to be the case for the work described by Furuse et al. on page 1099. The standard view of epithelial structure is that continuous tight junctions (TJs) are required only in simple epithelia like those that separate internal organs, b ...
The cancer stem cell: premises, promises and challenges
The cancer stem cell: premises, promises and challenges

... available to the CSC researcher of solid tumors. Indeed, Al-Hajj et al.24 chose the CD24 and CD44 marker combination, as these markers showed heterogeneous expression in breast tumors, and not because they were known to define breast epithelial stem cells. Another commonly used marker in CSC studies ...
Functions of the exocyst complex in secretion and cell wall biogenesis
Functions of the exocyst complex in secretion and cell wall biogenesis

... sequenced and assembled. However, even such a well characterized genome contains errors caused by imperfect computational assembling at regions of tandem duplications. Gene duplication events are common in plant evolution and that also applies for the genes coding for subunits of the exocyst. Initia ...
FROM THE LEAVES OF PHYLLOSTACHYS BAMBUSOIDES
FROM THE LEAVES OF PHYLLOSTACHYS BAMBUSOIDES

... In order to evaluate the role of ethyl acetate fraction (PB-EtAC) obtained from the Phyllostachys bambusoides leaves in the modulation of immune responses, detailed studies were carried out using a panel of in vivo assays. Oral administration of PB-EtAC (50–200 mg/Kg) stimulated the IgM and IgG titr ...
The Inability of the Mouse mdr2 Gene to Confer
The Inability of the Mouse mdr2 Gene to Confer

... transfection experiments. Mouse mdrl and mdr3 and human MDRJ can directly confer drug resistance to otherwise drug-sensitive cells in transfection experiments (12, 15), while mouse mdr2 (1 1, 16), and human MDR2 apparently cannot (17). Although the normal physiological role of individual human and m ...
Morphological Basis for the Cytolytic Effect of
Morphological Basis for the Cytolytic Effect of

... inward shift of Ca@ during mitosis is responsible not only for the breakdown of this differential but also possibly leads to chromosomal condensation ( I 3). In view of observations showing that vinblastine in higher concentrations acts like Ca@@and precipitates a number of cellular proteins as well ...
plant and animal cell remedation
plant and animal cell remedation

... surrounds the cell membrane; helps to protect and support the cell; materials such as water and oxygen can move through easily located just within the cell wall; controls what substance come into and out of a cell; needed materials are allowed into the cell and waste products are removed the cell’s ...
view as pdf - KITP Online
view as pdf - KITP Online

... Terminal differentiation ...
Tumor Specific Antigens
Tumor Specific Antigens

... increase in metabolism and central effects of tumor on hypothalamus • Probably related to macrophage production of TNF-a ...
7.3 cell transport
7.3 cell transport

... Cells in an isotonic solution experience no net gain or loss of water. ...
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SULF1

Sulfatase 1, also known as SULF1, is an enzyme which in humans is encoded by the SULF1 gene.Heparan sulfate proteoglycans (HSPGs) act as co-receptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endo-sulfatases, such as SULF1, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.
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