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Polysaccharides
Polysaccharides

... b. Sulfate and phosphate are both highly negatively charged, so they repel each other and the bond between them is easily broken. XXVI. Proteoglycans [S26] a. Can be simple (a small protein with a single chondroitin sulfate chain) or long chains (proteoglycans with hundreds of chondroitin sulfate ch ...
Aluminum stress and its role in the phospholipid signaling pathway
Aluminum stress and its role in the phospholipid signaling pathway

... An embryogenic-suspension cell line of Coffea arabica var. Catuai was obtained from a dispersed callus. The callus was originally obtained from the cotyledonary leaves of zygotic embryos from seeds cultured in vitro in Murashige–Skoog media at half the normal ionic strength and at a pH of 4.3. Under ...
About 100 cases of small cell carcinoma
About 100 cases of small cell carcinoma

... • Very few of these tumors have been reported. Mucoepidermoid carcinomas show a mixture of mucusproducing and squamous epithelium. [150], [151] One case has been shown to arise from submucosal ectopic glands.[151] The prognosis is reportedly poor. A few Paneth cell carcinomas have been reported as w ...
Ribosome biogenesis and cell growth: mTOR coordinates
Ribosome biogenesis and cell growth: mTOR coordinates

... transcription factor FHL1 together with its co-activator IFH1 and its co-repressor CRF1 (Martin et al., 2004; Schawalder et al., 2004; Rudra et al., 2005). Under favorable conditions, FHL1 binds to the promoter and activates RP gene transcription. TOR, via protein kinase A (PKA), maintains the co-re ...
Mutant p53 and chromatin regulation
Mutant p53 and chromatin regulation

... the transcription factor that it encodes to bind to abnormal targets, leading to cancer. Zhu et al.3 report that gain-of-function p53 binds to the transcription factor ETS2 and activates the genes MLL1, MLL2 and MOZ. MLL1 and MLL2 encode MLL enzymes that add methyl groups (Me) to the histone protein ...
Sickle cell anaemia
Sickle cell anaemia

... system) is the main organ which removes old and damaged RBCs from the circulation. • Breakdown of RBCs can exceed the rate that the body can make RBCs and so anemia can ...
ppt - Chair of Computational Biology
ppt - Chair of Computational Biology

... - different cyclin-Cdk complexes are activated at different points in the cell cycle, - cyclins must be destroyed before cells can escape from mitosis, and that - mitotic cyclins were destroyed by ubiquitin-mediated proteolysis Murray AW, Cell 116, 221-234 (2004) SS 2015 - lecture 5 ...
PPT File
PPT File

... What would your hypothesis be if you found a cluster of fuzzy black growth in an empty plastic container in your cabinet? 1. The container gave rise to this growth. 2. There were microscopic portions of this growth that gave rise to this larger colony. 3. The fuzzy growth is not a growth, but part ...
Control of plant cell differentiation by histone modification
Control of plant cell differentiation by histone modification

... number of methyl groups added to each lysine residue. Trimethylation of Histone H3 at lysine 4 (H3K4me3) is typically associated with active gene expression while trimethylation at lysine 27 (H3K27me3) is linked with gene repression [25,26]. Several methyltransferases that undertake H3K4me3 have bee ...
to get the file - Chair of Computational Biology
to get the file - Chair of Computational Biology

... Typically, unmethylated clusters of CpG pairs are located in tissue-specific genes and in essential housekeeping genes, which are involved in routine maintenance roles and are expressed in most tissues. These clusters, or CpG islands, are targets for proteins that bind to unmethylated CpGs and initi ...
Genesis of Cardiac Arrhythmias
Genesis of Cardiac Arrhythmias

... Altered a.p. play a role in arrhythmias Likely due to glycosylation of Na channels Neuroamindase effects on WT Good for mice, what about humans? ...
The Vacuole - Konner Aldridge Enterprises
The Vacuole - Konner Aldridge Enterprises

Binding Analysis of the Estrogen Receptor to Its
Binding Analysis of the Estrogen Receptor to Its

... and shortening of the KRK probe from 35 to 15 base pairs. In the presence of Mg:+ the KR-KRK complex formation was hormone depend ent at 22°Cbut not at 37°C.In the absence of Mg;+ estradiol was not necessary for KR-KRK complex formation. Correlation of the mobility shift assay with the hormone-bin ...
Slide 1
Slide 1

... believed to derived from apocrine sweat glands or, less often, from eccrine sweat glands. It is an exceedingly rare neoplasm, appearing at birth or arising during infancy, around the time of puberty, or later in life. Three clinical types have been described : The linear type is usually seen on the ...
Yamada et al., Cell 2005
Yamada et al., Cell 2005

... maintain physical interactions between cells  Pcdh-α proteins in mice have a RGD motif that can facilitate interactions with integrins in vitro  Protocadherins play a crucial role during embryogenesis, particularly in the CNS  These functions require activation of intracellular signaling in ...
HeLa cells
HeLa cells

... Background Cont. • Ultimately, genotoxic stress leads to activation of either JNK or MAP Kinases or both. • Activity regulated via reversible phosphorylation threonine tyrosine of ___________and ___________residues. So, what de-phosphorylates threonine and tyrosine residues? ...
Stomatal development: cross talk puts mouths in place
Stomatal development: cross talk puts mouths in place

Program and course description 16.4.- 20.4.2012
Program and course description 16.4.- 20.4.2012

... determination of cell phenotype through regulation of marker gene expression. To describe how microRNA signatures of cell phenotypes are determinant for normal organ functioning and pathophysiology. Lectures by Jan Oxholm Gordeladze 1. Introduction to the course: MicroRNAs, synthesis and function (1 ...
Protein Synthesis, Cell Division and the Cell Cycle in
Protein Synthesis, Cell Division and the Cell Cycle in

... to YEPD medium, protein synthesis continued at the:pre-shift rate for 70 rnin before increasing to the new rate (mass doubling time, 150 min) (Fig. 2). The rate of cell division continued at the pre-shift rate for 190 min before increasing to the value characteristic of the post-shift medium (Fig. 2 ...
CHAPTER 3: CELLS
CHAPTER 3: CELLS

... flattened membranous sacs ("cisternae") arranged in stacks ("stack of pancakes") associated with many vesicles (membrane bound sacs containing proteins); Function = modification, packaging, and transport of proteins; Vesicles pinch off as "secretory vesicles". See Fig 3.12, page 71. ...
Is Liver Disease Caused by Increased Pressure? Interstitial
Is Liver Disease Caused by Increased Pressure? Interstitial

Protein Synthesis, Cell Division and the Cell Cycle in
Protein Synthesis, Cell Division and the Cell Cycle in

... to YEPD medium, protein synthesis continued at the:pre-shift rate for 70 rnin before increasing to the new rate (mass doubling time, 150 min) (Fig. 2). The rate of cell division continued at the pre-shift rate for 190 min before increasing to the value characteristic of the post-shift medium (Fig. 2 ...
Collagen Type IV (H-234): sc
Collagen Type IV (H-234): sc

... BACKGROUND ...
Chemotaxis
Chemotaxis

... • postulate: (I) cell has both clusters and single receptors in equilibrium and (ii) spread is controlled in response to external conditions • spread will be lowest when cell has adapted to high concentrations of attractant; highest when not adapted • model can account for observed dynamic range Is ...
Logic of Definitions
Logic of Definitions

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SULF1

Sulfatase 1, also known as SULF1, is an enzyme which in humans is encoded by the SULF1 gene.Heparan sulfate proteoglycans (HSPGs) act as co-receptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endo-sulfatases, such as SULF1, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.
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