Centrosome Dynamics during the Meiotic Progression in the Mouse
... observed at metaphase-I and -II occurs when both maturation promoting factor and cytostatic factor levels are thought to be elevated. Purified centrosomes injected into unactivated metaphaseII-arrested Xenopus oocytes do not support microtubule growth. However, when these eggs are artificially activ ...
... observed at metaphase-I and -II occurs when both maturation promoting factor and cytostatic factor levels are thought to be elevated. Purified centrosomes injected into unactivated metaphaseII-arrested Xenopus oocytes do not support microtubule growth. However, when these eggs are artificially activ ...
郭憲壽
... Synthesis and Biological Evaluation of Novel Bis-Aziridinylnaphthoquinone Derivatives Oncology Research 13 199-204 (SCI) 7. Lin, Y. L., Kuo, H. S. Wang, Y. W., Huang, S. T.* (2003) Efficient Entry to 1-benzoxepine ring skeleton via Tandem SN2/Wittig Reaction. Total Synthesis of NADH:Ubiquinone Oxido ...
... Synthesis and Biological Evaluation of Novel Bis-Aziridinylnaphthoquinone Derivatives Oncology Research 13 199-204 (SCI) 7. Lin, Y. L., Kuo, H. S. Wang, Y. W., Huang, S. T.* (2003) Efficient Entry to 1-benzoxepine ring skeleton via Tandem SN2/Wittig Reaction. Total Synthesis of NADH:Ubiquinone Oxido ...
Inhibition of Tumor Cell Invasion by a Highly Conserved Peptide
... others have used specific inhibitors of the matrix metalloproteinases, tissue inhibitors of metalloproteinases, to directly block tumor cell invasion in vitro (5-8). These studies suggest that metalloprotease activity in general, and specifically the 72kDa type IV collagenase, is required for tumor ...
... others have used specific inhibitors of the matrix metalloproteinases, tissue inhibitors of metalloproteinases, to directly block tumor cell invasion in vitro (5-8). These studies suggest that metalloprotease activity in general, and specifically the 72kDa type IV collagenase, is required for tumor ...
ppt - Chair of Computational Biology
... macrophages are potent producers of IL-1, IL-6, and TNF-α. In contrast, classic hormones, such as insulin, are secreted from discrete glands (e.g., the pancreas). www.wikipedia.org SS 2015 – lecture 10 ...
... macrophages are potent producers of IL-1, IL-6, and TNF-α. In contrast, classic hormones, such as insulin, are secreted from discrete glands (e.g., the pancreas). www.wikipedia.org SS 2015 – lecture 10 ...
hnpcc recommendations B.pub - Association for Clinical Genetic
... variation in fixation of the epitope or effects of epitope retrieval, which are not biological phenomena. Geneticists wish to know if there is an abnormal expression pattern that reflects genetic abnormalities, and this requires identification of a well fixed part of the tumour where the intensity o ...
... variation in fixation of the epitope or effects of epitope retrieval, which are not biological phenomena. Geneticists wish to know if there is an abnormal expression pattern that reflects genetic abnormalities, and this requires identification of a well fixed part of the tumour where the intensity o ...
BAFF Binds to the Tumor Necrosis Factor Receptor–like
... an increased number of effector T cells in their spleen and mesenteric lymph nodes (6). These mice display autoimmune-like manifestations including high levels of rheumatoid factors, circulating immune complexes, anti-DNA autoantibodies, and Ig deposition in the kidney (6). However, splenic B cells ...
... an increased number of effector T cells in their spleen and mesenteric lymph nodes (6). These mice display autoimmune-like manifestations including high levels of rheumatoid factors, circulating immune complexes, anti-DNA autoantibodies, and Ig deposition in the kidney (6). However, splenic B cells ...
Role of inducible NO synthase in cell signalling
... complex factors or STATs and, finally, perhaps lead to alterations in gene expression. Modulation of transcription factors and gene expression by NO The molecular mechanisms by which NO affects gene expression are still poorly understood, and an ultimate ‘NOresponsive promoter element’ has yet to be ...
... complex factors or STATs and, finally, perhaps lead to alterations in gene expression. Modulation of transcription factors and gene expression by NO The molecular mechanisms by which NO affects gene expression are still poorly understood, and an ultimate ‘NOresponsive promoter element’ has yet to be ...
V. CELL TRANSPORT, cont
... • Typically involves 3 steps: Reception – Target cell’s detection of signal molecule due to binding of signal molecule to receptor protein in cell membrane Transduction – Binding of signaling molecule changes receptor protein; triggers a sequence of events within cell Response – Results in spe ...
... • Typically involves 3 steps: Reception – Target cell’s detection of signal molecule due to binding of signal molecule to receptor protein in cell membrane Transduction – Binding of signaling molecule changes receptor protein; triggers a sequence of events within cell Response – Results in spe ...
SP600125 Selectively Inhibits Histone H3
... chromatin dynamics (1). Many types of cancer are associated with translocations or mutations in chromatin modifying enzymes and regulatory proteins. The phosphorylation of histone H3 at serine 10 (histone H3-Ser10) is conserved through eukaryotes, and an increase in phosphorylation has been shown to ...
... chromatin dynamics (1). Many types of cancer are associated with translocations or mutations in chromatin modifying enzymes and regulatory proteins. The phosphorylation of histone H3 at serine 10 (histone H3-Ser10) is conserved through eukaryotes, and an increase in phosphorylation has been shown to ...
The expression of transforming growth factor-βs and TGF
... thymidine incorporation and cell proliferation assay. Standard RT–PCR and immunocytochemistry revealed that myometrial smooth muscle cells express TGFβ1–3 and TGF-β type I–III receptor (TGF-βR) mRNA and protein. Quantitative RT–PCR, using an external synthetic RNA standard, indicated that the cells ...
... thymidine incorporation and cell proliferation assay. Standard RT–PCR and immunocytochemistry revealed that myometrial smooth muscle cells express TGFβ1–3 and TGF-β type I–III receptor (TGF-βR) mRNA and protein. Quantitative RT–PCR, using an external synthetic RNA standard, indicated that the cells ...
Local interactions shape plant cells
... unclear whether, as in yeast [23], it represents an aggregation of fine-branched networks, which could suggest a region of focused actin nucleation and polymerization activities. Nevertheless, an ARP2 (actin-related protein 2) homolog localizes to the bulge domain in polarized fucus zygotes [24], ...
... unclear whether, as in yeast [23], it represents an aggregation of fine-branched networks, which could suggest a region of focused actin nucleation and polymerization activities. Nevertheless, an ARP2 (actin-related protein 2) homolog localizes to the bulge domain in polarized fucus zygotes [24], ...
``Self-Assisted`` Amoeboid Navigation in Complex Environments
... of a repulsive chemical by the agent, helps the agent escape from such trapping. Conclusions/Significance: Our main conclusion is that cells employing simple chemotactic strategies will often be unable to navigate through maze-like geometries, but a simple chemical marker mechanism (which we refer t ...
... of a repulsive chemical by the agent, helps the agent escape from such trapping. Conclusions/Significance: Our main conclusion is that cells employing simple chemotactic strategies will often be unable to navigate through maze-like geometries, but a simple chemical marker mechanism (which we refer t ...
Redox Homeostasis and Signaling - University of Nebraska–Lincoln
... In bacteria and unicellular eukaryotes, the induced expression of detoxifying enzymes in response to ROS plays a major role in protecting the cell against oxidative damage. In multicellular organisms, the increased expression of antioxidant enzymes is not a universal response of all cells to ROS, ho ...
... In bacteria and unicellular eukaryotes, the induced expression of detoxifying enzymes in response to ROS plays a major role in protecting the cell against oxidative damage. In multicellular organisms, the increased expression of antioxidant enzymes is not a universal response of all cells to ROS, ho ...
Biology / Biochemistry News
... "What we see now for the first time in the Science paper is that there are enzymes that are removing NO from proteins to control protein activity," Stamler said. "This action has a broad-based effect, frankly, and probably happens in virtually all cells and across all protein classes. Nitric oxide i ...
... "What we see now for the first time in the Science paper is that there are enzymes that are removing NO from proteins to control protein activity," Stamler said. "This action has a broad-based effect, frankly, and probably happens in virtually all cells and across all protein classes. Nitric oxide i ...
IDENTIFICATION OF CD133+/NESTIN+ PUTATIVE CANCER STEM
... osteocarcoma, ...)17,32. The NSCLC epithelial precursors described so far have been only CD133+ cells. For this study we examined the co-expression of nestin and CD133 in pulmonary tumours. Nestin expression was significantly stronger than the expression of CD133, and thus we could follow the positi ...
... osteocarcoma, ...)17,32. The NSCLC epithelial precursors described so far have been only CD133+ cells. For this study we examined the co-expression of nestin and CD133 in pulmonary tumours. Nestin expression was significantly stronger than the expression of CD133, and thus we could follow the positi ...
The added value of single-cell gene expression
... processed later in the workflow (Figure 2). How can one tell whether missing data are due to technical failures or expression levels below the limit of detection? The transcriptome of typical mammalian cells consists of about 300 000 mRNA molecules represented by some 10 000 expressed genes [26]. So ...
... processed later in the workflow (Figure 2). How can one tell whether missing data are due to technical failures or expression levels below the limit of detection? The transcriptome of typical mammalian cells consists of about 300 000 mRNA molecules represented by some 10 000 expressed genes [26]. So ...
Publications de l`équipe
... In multicellular organisms, distant cells can exchange information by sending out signals composed of single molecules or, as increasingly exemplified in the literature, via complex packets stuffed with a selection of proteins, lipids, and nucleic acids, called extracellular vesicles (EVs; also known ...
... In multicellular organisms, distant cells can exchange information by sending out signals composed of single molecules or, as increasingly exemplified in the literature, via complex packets stuffed with a selection of proteins, lipids, and nucleic acids, called extracellular vesicles (EVs; also known ...
C) Cells and Transport Practice Qs
... ____ 23. What type of organelle would be abundant in a skeletal muscle cell? a. ribosomes c. Rough ER b. lysosome d. mitochondria ____ 24. Which of the following structures is found in the cytoplasm? a. DNA c. chromatin b. ribosome d. nucleolus ____ 25. The cell membrane contains channels and pumps ...
... ____ 23. What type of organelle would be abundant in a skeletal muscle cell? a. ribosomes c. Rough ER b. lysosome d. mitochondria ____ 24. Which of the following structures is found in the cytoplasm? a. DNA c. chromatin b. ribosome d. nucleolus ____ 25. The cell membrane contains channels and pumps ...
NOBEL LECTURE: Yeast and Cancer
... variation in disease susceptibility. In the first two instances, yeast has told us something that is relevant to mankind. For the other two, it is too soon to tell. When I was finishing my graduate studies and thinking about what area of science to pick for my postdoctoral work, I wanted to study a ...
... variation in disease susceptibility. In the first two instances, yeast has told us something that is relevant to mankind. For the other two, it is too soon to tell. When I was finishing my graduate studies and thinking about what area of science to pick for my postdoctoral work, I wanted to study a ...