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Cellular Division
Cellular Division

... cRNA (catalytic RNA) catalyses many reactions in the cytoplasm of the cell. snRNA (small nuclear RNA) have various roles in the processing of the other classes of RNA. snoRNA (small nucleolar RNA) over 100 of them found in the nucleolus where they are involved in several functions including making r ...
Chapter 2
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... The core of every living being is its genetic payload. The genetic inheritance describes information that is passed down from parents to their offspring. It contains a blueprint detailing, in essence, how to construct a new individual from a single cell. This genetic inheritance is physically presen ...
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... Consensus sequences, e.g. TATA box 2. Chain initiation & elongation RNA synthesis begins at transcription start site, next to the promoter Again: 5' to 3' elongation ...
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... the amino acids, such as Ser for serine.) The codon AUG not only stands for methionine (Met), but also functions as a signal to "start" translating an RNA transcript. There are also three "stop" codons that do not code for amino acids, but signal the end of each genetic message. ...
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CHEM642-07 Powerpoint
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Genetic regulation of eukaryotes
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bcdcdbcaab - kehsscience.org
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... RNA is usually double-stranded and contains the base thymine. RNA is usually single-stranded and contains the base uracil. RNA is longer than DNA and uses five bases to encode information. RNA is made in the nucleus of eukaryotic cells and stays there to carry out its functions. ...
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RNA - Gulf Coast State College

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... • There are 64 (43) possible codes, but only 20 amino acids. • More than 1 triplet may code for the same amino acid. This is fine as long as no triplet can code for more than one a.acid. • Note that several codons can also act as start (AUG) or stop (UAA) signals. ...
Exam2key - Biology Courses Server
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... __F___ Loss of the 3’-5’ exonuclease activity of DNA polymerase will slow the rate of DNA synthesis but not its fidelity (accuracy). __F___ dATP inhibits the phosphofructokinase whereas ADP stimulates it. __F___ All the nucleotides in a mRNA sequence are translated into protein. ...
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... Introduction to protein synthesis • Each cell’s DNA can be seen as a book of protein-building instructions. The alphabet used in this book is simple A, T, G and C. • The DNA molecules for the formation of proteins occurs in genes on chromosomes. • Memorise the matching of these bases and between A ...
Chapter 12: Mechanisms and Regulation of Transcription I
Chapter 12: Mechanisms and Regulation of Transcription I

... stimulated by hSPT5 6. The 5’ Cap is added to the 5’ end of the RNA in three steps 7. The first step in cap addition is removal of a phosphate group from the 5’ end of the RNA by the RNA triphosphatase enzyme 8. The second step is addition of the GMP moiety to the βphosphate of the first nucleotide ...
No Slide Title
No Slide Title

... thymine adenine cytosine guanine ...
(2) rRNA
(2) rRNA

... play a direct role in translation: ex., The 23S rRNA is the peptidetransferase (a kind of ribozyme). The 16S rRNA is directly involved in both initiation and termination of translation. v. in many bacteria, the coding sequences for rRNAs are repeated in 7 to 10 different places around the genome. vi ...
RNA Ligands to Bacteriophage T4 DNA Polymerase
RNA Ligands to Bacteriophage T4 DNA Polymerase

... • Other mutations around this region can provide a higher binding energy, but are not as well conserved. ...
Chapter 3 - Cell Protein Production
Chapter 3 - Cell Protein Production

... • The strand that is copied is called the template strand because it is the template from which the mRNA is made. The other strand is known as the coding strand • Not all of the bases in the DNA molecule are code for an amino acid. The noncoding sequences are called introns © 2010 McGraw-Hill Austra ...
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Polyadenylation



Polyadenylation is the addition of a poly(A) tail to a messenger RNA The poly(A) tail consists of multiple adenosine monophosphates; in other words, it is a stretch of RNA that has only adenine bases. In eukaryotes, polyadenylation is part of the process that produces mature messenger RNA (mRNA) for translation. It, therefore, forms part of the larger process of gene expression.The process of polyadenylation begins as the transcription of a gene finishes, or terminates. The 3'-most segment of the newly made pre-mRNA is first cleaved off by a set of proteins; these proteins then synthesize the poly(A) tail at the RNA's 3' end. In some genes, these proteins may add a poly(A) tail at any one of several possible sites. Therefore, polyadenylation can produce more than one transcript from a single gene (alternative polyadenylation), similar to alternative splicing.The poly(A) tail is important for the nuclear export, translation, and stability of mRNA. The tail is shortened over time, and, when it is short enough, the mRNA is enzymatically degraded. However, in a few cell types, mRNAs with short poly(A) tails are stored for later activation by re-polyadenylation in the cytosol. In contrast, when polyadenylation occurs in bacteria, it promotes RNA degradation. This is also sometimes the case for eukaryotic non-coding RNAs.mRNA molecules in both prokaryotes and eukaryotes have polyadenylated 3'-ends, with the prokaryotic poly(A) tails generally shorter and less mRNA molecules polyadenylated.
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