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Metabolism-Antibiotic Sensitivity
Metabolism-Antibiotic Sensitivity

... starts with the association of mRNA, a 30S ribosomal subunit, and formyl-methionyltransfer RNA (fMet-tRNA) to form a 30S initiation complex. The formation of this complex also requires guanosine triphosphate (GTP) and the participation of three protein initiation factors. The codon AUG is the initia ...
Biology 6B
Biology 6B

... Use 6 red pop cylinders to represent one portion of the promoter. Attach 6 white pop cylinders to represent the L region containing the attenuator. Use 8 yellow pop cylinders to represent the regulatory gene. Use red pop beads to represent the mRNA of the regulatory gene. Use the wooden block labele ...
6th Year Biology Higher Level Wesley Hammond DNA and RNA
6th Year Biology Higher Level Wesley Hammond DNA and RNA

... DNA and RNA can be worth 5% if asked as a short question in Section A. DNA and RNA can be worth 7.5% if asked as an experiment in Section B. DNA and RNA can be worth 15% if asked as a long question in Section C. Note: DNA and RNA question has been asked every year since 2004 except for ...
Functional Genomics
Functional Genomics

... Basal functions of eukaryotes are shared: - lethal (Nonv) genes tended to be of ancient origin - ‘animal-specific’ genes tended to be non-lethal (Vpep) - almost no ‘worm-specific’ genes were lethal ...
Document
Document

... – DNA is composed of four nucleotides or bases: si  {A, C, G, T} – RNA is composed of four nucleotides: si  {A, C, G, U}(T is transcribed as U) – Proteins are composed of twenty amino acids CS369 2007 ...
SBI4U: Molecular Genetics Unit Review
SBI4U: Molecular Genetics Unit Review

... complementary to the third base on the codon. Since the genetic code is redundant, with codons for the same A.A. differing usually at the last base, it allows the correct amino acid to be delivered to the ribosome despite the fact that the anticodon and codon may not be 100% complementary. Regulatio ...
7 Molecular Genetics: From DNA to Proteins
7 Molecular Genetics: From DNA to Proteins

... In eukaryotes, the new mRNA is not yet ready for translation. It must go through more processing before it leaves the nucleus. This may include splicing, editing, and polyadenylation. These processes modify the mRNA in various ways. Such modifications allow a single gene to be used to make more than ...
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... A higher proportion of histone H1 would be found in frog fibroblast cells. A higher proportion of histone H2B would be found in human fibroblasts. The non-histone proteins isolated from frog would be highly similar to the non-histone proteins isolated from human fibroblasts. The histone proteins iso ...
Nucleic Acids - Somma Science
Nucleic Acids - Somma Science

... (C), adenine (A), guanine (G), and either thymine (T) in DNA, or uracil (U) in RNA. In DNA, bonds form between bases on the two nucleotide chains and hold the chains together. Each type of base binds with just one other type of base: cytosine always binds with guanine, and adenine always binds with ...
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... tissue sarcomas, are tumours related to the skeletal muscle lineage. The 2 major subtypes are alveolar rhabdomyosarcoma (ARMS) and embryonal rhabdomyosarcoma (ERMS). Other subtypes are botryoid, spindle cell, anaplastic, pleomorphic, and undifferentiated RMS. Most ERMS are characterized by chromosom ...
U2Word
U2Word

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... (C), adenine (A), guanine (G), and either thymine (T) in DNA, or uracil (U) in RNA. In DNA, bonds form between bases on the two nucleotide chains and hold the chains together. Each type of base binds with just one other type of base: cytosine always binds with guanine, and adenine always binds with ...
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... gene, a ribonucleoprotein. There are two other microRNAs in the human genome that yield mature miR-7, with all three miR-7 loci found on different chromosomes. ...
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Genome-wide RNAi screening in Caenorhabditis elegans
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... •1984: Stout & Caskey show antisense RNA can be used to silence gene expression in Mammalian tissue cultures •1990: Fire & Moerman show antisense RNA can disrupt myofilament protein encoding genes •1995: Guo & Kemphues accidentally discover that sense RNA can is as effective as antisense RNA in gene ...
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... gene transcripts. The false positive rate with DDRT-PCR can be highly variable and therefore it can be best used as a screening procedure rather than a cloning strategy. A similar RT-PCR screening technique called RAP-PCR (RNA arbitrarily primed PCR), is based on a genomic DNA fingerprinting strateg ...
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... Simulating Protein Synthesis to create a CHNOPS! Read the following to help you complete a successful CHNOPS organism.  Genes are the units that determine inherited characteristics such as hair color as blood type. Genes consist of DNA molecules that code for the proteins our cells make. The sequen ...
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... Highly conserved pathway across species and domains Mammalian (RNAi); Bacteria (CRISPR) Post-transcriptional modulation of gene expression Mediated by formation of RNA-induced silencing complex (RISC) with small non-coding (ncRNA) as guide RNA Binding of microRNA to mRNA either results in mRNA cleav ...
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... The genetic code as we find it today To judge the significance of the DRT model, laid out most fully by Yarus et al. in their 2009 review [11], we need first to describe what needs to be explained in more detail. The genetic code as we observe it today is a semantic (symbolbased) relation between (a ...
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... turns out not to be ‘junk’ at all; instead it is composed of important sequences that can regulate how and when gene expression occurs. The DNA sequences that directly code for amino acids are called exons (called genes in Figure 1). Interspersed within exons are sequences called introns. Introns ar ...
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1. Nucleic Acids and Chromosomes

... complex. The DNA sequences at which the initiation complex assembles is called a gene promoter. 5. Describe what is meant by a “Transcription factor” The rate/level of transcription from a given gene is regulated by the activity of DNA binding proteins, or Transcription Factors. These can be transcr ...
Document
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... TRANSFAC Database TRANSFAC® is a database on eukaryotic cis-acting regulatory DNA elements and trans-acting factors. It covers the whole range from yeast to human. It started 1988 with a printed compilation and was transferred into computerreadable format in 1990. The FACTOR table contains 6133 ent ...
Gene Regulation Notes
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... 18.2 Organization of a Typical Eukaryotic Gene • Associated with most eukaryotic genes are control elements, segments of noncoding DNA that help regulate transcription by binding certain proteins • Control elements can be proximal (close) to the gene, or distal (far from the gene, thousands of ...
1) From DNA to protein 2) Gene mutation
1) From DNA to protein 2) Gene mutation

... •  Wobble base pair •  The genetic code is not ambiguous—each codon specifies only one amino acid. •  The genetic code is nearly universal: The codons that specify amino acids are the same in all organisms. •  Exceptions: within mitochondria and chloroplasts, and in one group of protists, there are ...
Regulation of Gene Expression
Regulation of Gene Expression

... -RNA-mediated regulation of gene expression takes many forms in Eukaryotes -Development is controlled by cascades of regulatory proteins ...
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Non-coding RNA



A non-coding RNA (ncRNA) is an RNA molecule that is not translated into a protein. Less-frequently used synonyms are non-protein-coding RNA (npcRNA), non-messenger RNA (nmRNA) and functional RNA (fRNA). The DNA sequence from which a functional non-coding RNA is transcribed is often called an RNA gene.Non-coding RNA genes include highly abundant and functionally important RNAs such as transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), as well as RNAs such as snoRNAs, microRNAs, siRNAs, snRNAs, exRNAs, and piRNAs and the long ncRNAs that include examples such as Xist and HOTAIR (see here for a more complete list of ncRNAs). The number of ncRNAs encoded within the human genome is unknown; however, recent transcriptomic and bioinformatic studies suggest the existence of thousands of ncRNAs., but see Since many of the newly identified ncRNAs have not been validated for their function, it is possible that many are non-functional. It is also likely that many ncRNAs are non functional (sometimes referred to as Junk RNA), and are the product of spurious transcription.
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