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Breanna Perreault D145 Presentation 2/23/17 Background
Breanna Perreault D145 Presentation 2/23/17 Background

... CpGs: Consecutive C and G nucleotides, sequence that can be directly methylated ...
Tumor-suppressor genes
Tumor-suppressor genes

...  DNA packing can prevent gene expression by preventing RNA polymerase & other proteins from contacting the DNA.  Cells seem to use higher levels of packing for long-term inactivation of genes.  Highly compacted chromatin is generally not expressed ...
Promoter Regions
Promoter Regions

... Transcription Start Site: The beginning of RNA transcription. Downstream of binding sequences. Activator: A protein that binds DNA and stabilizes the binding of transcription factors. Activator Site: The region of DNA an activator binds to. Repressor: A protein that binds DNA and destabilizes the bi ...
Simulating Protein Synthesis 01/04
Simulating Protein Synthesis 01/04

... Genes are the units that determine inherited characteristics, such as hair color and blood type. Genes are segments of DNA molecules that determine the structure of polypeptide chains (proteins) that our cells make. The sequence of nucleotides in DNA determines the sequence of amino acids in polypep ...
Ensembl
Ensembl

... snRNA (small nuclear) snoRNA (small nucleolar) miRNA (microRNA) 28 of 32 ...
Study Guide for Macromolecules
Study Guide for Macromolecules

... Subunits are amino acids. Basic structure of an amino acid 20 kinds of amino acid used in proteins, based on different R groups R groups can be charged (+ or -), uncharged but polar (hydrophilic), or non-polar (hydrophobic) Dehydration of the –OH in the carboxylic acid group and an –H in the amino g ...
video slide
video slide

... expression by blocking the binding of activators to their control elements or to components of the transcription machinery or by turning off transcription even in the presence of activators. ...
Mutations Worksheet
Mutations Worksheet

... BONUS: You have a DNA sequence that codes for a protein and is 105 nucleotides long. A frameshift mutation occurs at the 85th base - how many amino acids will be correct in this protein? SHOW YOUR WORK. ...
12-4 Notes
12-4 Notes

... changed because they are read in groups of three.  This can cause the gene to produce a completely different protein.  It can be altered so much that it is unable to perform its normal functions.  EX: insertion or deletion ...
Introductory Speaker, Jonathan Pevsner: "Genomics, Bioinformatics
Introductory Speaker, Jonathan Pevsner: "Genomics, Bioinformatics

... in self-injurious behavior? In many cases, there are chromosomal insults. ...
BDOL Interactive Chalkboard - Broken Arrow Public Schools
BDOL Interactive Chalkboard - Broken Arrow Public Schools

... amino acid in the protein after the deletion to be changed. • A mutation in which a single base is added or deleted from DNA is called a frameshift mutation because it shifts the reading of codons by one base. ...
Gene Section BRWD3 (bromodomain and WD repeat domain containing 3)
Gene Section BRWD3 (bromodomain and WD repeat domain containing 3)

... Note: In the tumour cells of one case of B-cell chronic lymphocytic leukemia (B-CLL), BRWD3 was affected by a translocation that rearranged the gene with ARHGAP20 (11q23). No fusion transcripts were generated. BRWD3 transcript expression is downregulated in B-CLL lymphocytes vs. CD19+ control B cell ...
Mendelian Genetics - Home | Phoenix College
Mendelian Genetics - Home | Phoenix College

... • Pleiotropy is the impact of a single gene on more than one characteristic. These characteristics are thus usually expressed together. Examples: Red hair and freckles or sickle-cell disease ...
DNA Review Sheet Answers
DNA Review Sheet Answers

... How do you know? All the DNA moved right one base ...
when glucose is scarce
when glucose is scarce

... • How the components of an operon function to regulate gene expression in both repressible and inducible operons. ...
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blank worksheet

... Normalisation: Which reference gene(s) were used to calculate the relative expression of the ...
14: The Eukaryotic Genome and Its Expression
14: The Eukaryotic Genome and Its Expression

... In prokaryotes, the promoter is a DNA recognition sequence about 40 bp from the 5¢ initiation point and a TATA box (area rich in AT base pairs) just upstream from the intersection point. • In contrast, in eukaryotes the TATA box is about 25 bp away from the initiation site, and one or two recogniti ...
The Blueprint of Life, From DNA to Protein
The Blueprint of Life, From DNA to Protein

... – inhibits gene expression and decreases the synthesis of enzymes – usually in response to the overabundance of an end product – Repressors block the ability of RNA polymerase to bind and initiate protein synthesis – Corepressor – inducer ...
General Biology I (BIOLS 102)
General Biology I (BIOLS 102)

...  Results in the release the mRNA transcript  Many RNA polymerase molecules work to produce mRNA from the same DNA region at the same time  Either strand of DNA can be a template strand but for a different gene ...
emboj200956-sup
emboj200956-sup

... et al., 2006). For about 1/3 of the tested factors the real-time PCR results were confirmed by Northern Blot. Aberrant transcription initiation or apparent processing defects were not observed for any of the tested factors by Northern Blot. Primer sequences for designing the dsRNA targeting the fact ...
Quiz Questions - The University of Sheffield
Quiz Questions - The University of Sheffield

... C.  Rough ER is the site of the synthesis of secreted and trans-membrane proteins. D.  Membrane-bound vesicles leave the ER to carry proteins into the Golgi apparatus. E.  Signalase clips off signal peptides from secreted proteins in the lumen of the ER. F.  Actually, all of the above statements are ...
Reverse_Transcription_PCR
Reverse_Transcription_PCR

... SYNTHESIS OF mRNA FROM DNA ...
No Slide Title
No Slide Title

... 3) Cloning from the protein: either from pr sequence, or using antibodies, or some biochemical property of the protein (e.g., or DNA binding) 4) By homology (low stringency hybridizat 5) POSITIONAL CLONING ...
Microbes in nutrition Digestion vast majority of GI tract bacteria are
Microbes in nutrition Digestion vast majority of GI tract bacteria are

... b. other applications = sewage treatment, control of insects, recovery of metals, various environmental uses c. biotechnology = generally implies use of recombinant DNA techniques to design proteins or modify gene expression (1) originally strains were selected and improved crudely, at most using no ...
Bacterial species
Bacterial species

... A type of DNA sequence in eukaryotes that helps to regulate transcription, may be tissue specific, and may exert control over a structural gene that is a great distance away is called 1. a promoter. 2. a Shine-Dalgarno sequence. 3. a TATA box. 4. an enhancer. ...
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Non-coding RNA



A non-coding RNA (ncRNA) is an RNA molecule that is not translated into a protein. Less-frequently used synonyms are non-protein-coding RNA (npcRNA), non-messenger RNA (nmRNA) and functional RNA (fRNA). The DNA sequence from which a functional non-coding RNA is transcribed is often called an RNA gene.Non-coding RNA genes include highly abundant and functionally important RNAs such as transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), as well as RNAs such as snoRNAs, microRNAs, siRNAs, snRNAs, exRNAs, and piRNAs and the long ncRNAs that include examples such as Xist and HOTAIR (see here for a more complete list of ncRNAs). The number of ncRNAs encoded within the human genome is unknown; however, recent transcriptomic and bioinformatic studies suggest the existence of thousands of ncRNAs., but see Since many of the newly identified ncRNAs have not been validated for their function, it is possible that many are non-functional. It is also likely that many ncRNAs are non functional (sometimes referred to as Junk RNA), and are the product of spurious transcription.
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