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Triton X-100 promotes a cholesterol

... We analysed the lipid structure of the cell surface of COS cells by means of two-photon microscopy. The fluorescent probe Laurdan has been used to characterize phase separation in model membranes [24,25] and visualize ordered domains on the surface of living cells [21]. Laurdan does not partition pr ...
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Lipid raft



The plasma membranes of cells contain combinations of glycosphingolipids and protein receptors organized in glycolipoprotein microdomains termed lipid rafts. These specialized membrane microdomains compartmentalize cellular processes by serving as organizing centers for the assembly of signaling molecules, influencing membrane fluidity and membrane protein trafficking, and regulating neurotransmission and receptor trafficking. Lipid rafts are more ordered and tightly packed than the surrounding bilayer, but float freely in the membrane bilayer. Although more common in plasma membrane, lipid rafts have also been reported in other parts of the cell, such as Golgi and lysosomes.
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