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mtCLIC/CLIC4 a Chloride Channel Protein Participates in Apoptosis
mtCLIC/CLIC4 a Chloride Channel Protein Participates in Apoptosis

... mtCLIC/CLIC4 (mtCLIC) is a p53 and TNF-α regulated cytoplasmic and mitochondrial protein that belongs to the CLIC family of intracellular chloride channels [1]. Overexpression of mtCLIC reduces mitochondrial membrane potential, releases cytochrome c into the cytoplasm, and induces apoptosis [2]. We ...
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... least some may pass more easily. It allows a cell to discriminate in its chemical exchanges with its environment. This is important to cells because it keeps them from spilling all their contents, keeping the bigger molecules, organelles, cytosol, etc. inside, while allowing the cell to get rid of u ...
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... •Membrane structure relies on the tendency of fatty acid  molecules to spread on the surface of water.  • Membrane proteins (which take up half of the  membrane) determine what gets into and leaves the cell. •Glycolipids are found on the outer part of the cell  membrane.   ...
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05_Clicker_Questions

... Which of the following best describes the structure of a biological membrane? A. two layers of phospholipids with proteins embedded between the two layers B. a mixture of covalently linked phospholipids and proteins that determines which solutes can cross the membrane and which cannot C. two layers ...
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Lipid raft



The plasma membranes of cells contain combinations of glycosphingolipids and protein receptors organized in glycolipoprotein microdomains termed lipid rafts. These specialized membrane microdomains compartmentalize cellular processes by serving as organizing centers for the assembly of signaling molecules, influencing membrane fluidity and membrane protein trafficking, and regulating neurotransmission and receptor trafficking. Lipid rafts are more ordered and tightly packed than the surrounding bilayer, but float freely in the membrane bilayer. Although more common in plasma membrane, lipid rafts have also been reported in other parts of the cell, such as Golgi and lysosomes.
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