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... ubiquitous transgene expression throughout development, equivalent to the Rosa26 locus used in mouse genetics. But no longer, for in one of Development’s inaugural Technical papers (p. 169), Leonard Zon and co-workers report that the zebrafish ubiquitin (ubi) promoter can drive constitutive transgen ...
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Chem*3560 Lecture 30: Ion pumps in the membrane

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... associated with a variety of receptors, they act as coreceptors for a number of heparin-binding growth factors, modulating their activity. The heparan sulfate modifications of glypicans can mediate interactions with growth factors or ECM proteins, but ligands and ECM proteins can also bind through m ...
< 1 ... 610 611 612 613 614 615 616 617 618 ... 1317 >

Signal transduction



Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.
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