STRUCTURE AND FUNCTION
... Keeping Ammonia Out. From the crystal structures and known features of the Amt and GlnK protein families, a mechanism was developed to explain regulation of ammonia uptake by a prokaryotic cell. One interesting aspect of the interactions between the two proteins is that an overall negative charge is ...
... Keeping Ammonia Out. From the crystal structures and known features of the Amt and GlnK protein families, a mechanism was developed to explain regulation of ammonia uptake by a prokaryotic cell. One interesting aspect of the interactions between the two proteins is that an overall negative charge is ...
T Gulick, SJ Pieper, MA Murphy, LG Lange and GF
... associated with an immune cell myocardial infiltrate such as cardiac allograft rejection and inflammatory myocarditis. We therefore examined the hypothesis that immune cells can produce noncytotoxic alterations in cardiac function. Methods and Results. A novel system to evaluate cultured cardiac myo ...
... associated with an immune cell myocardial infiltrate such as cardiac allograft rejection and inflammatory myocarditis. We therefore examined the hypothesis that immune cells can produce noncytotoxic alterations in cardiac function. Methods and Results. A novel system to evaluate cultured cardiac myo ...
Chemical Biology 03 BLOOD
... O2 to bind. • deoxyMb, deoxyHb, heme ring is puckered in absence of 6th ligand; Fe(II) out of plane. • oxyMb, oxyHb ring is flat with sixth ligand bound to Fe(II), metal is in heme plane. ...
... O2 to bind. • deoxyMb, deoxyHb, heme ring is puckered in absence of 6th ligand; Fe(II) out of plane. • oxyMb, oxyHb ring is flat with sixth ligand bound to Fe(II), metal is in heme plane. ...
The extracellular matrix at a glance
... chains composed of repeating disaccharide units [sulfated N-aceltylglucosamine or N-acetylgalactosamine, D-glucuronic or L-iduronic acid and galactose (–4 Nacetylglucosamine-1,3-galactose-1)] that can be divided further into sulfated (chondroitin sulfate, heparan sulfate and keratan sulfate) and n ...
... chains composed of repeating disaccharide units [sulfated N-aceltylglucosamine or N-acetylgalactosamine, D-glucuronic or L-iduronic acid and galactose (–4 Nacetylglucosamine-1,3-galactose-1)] that can be divided further into sulfated (chondroitin sulfate, heparan sulfate and keratan sulfate) and n ...
Anillin, a Contractile Ring Protein That Cycles from the Nucleus to
... 1994). The orientation of this ring is governed by the positions of the mitotic spindle through an unknown mechanism (Rappaport and Rappaport, 1974). During late anaphase, the cell cortex changes in the region where the cleavage furrow will form. Both myosin II and the recently identified septin pro ...
... 1994). The orientation of this ring is governed by the positions of the mitotic spindle through an unknown mechanism (Rappaport and Rappaport, 1974). During late anaphase, the cell cortex changes in the region where the cleavage furrow will form. Both myosin II and the recently identified septin pro ...
A General Method Applicable to the Search for Similarities in the
... A computer adaptable method forfinding similarities in the amino acid sequences of two proteins has been developed.From these findings it is possible to determine whether significant homology exists between the proteins. This information is used to trace their possible evolutionary development. The ...
... A computer adaptable method forfinding similarities in the amino acid sequences of two proteins has been developed.From these findings it is possible to determine whether significant homology exists between the proteins. This information is used to trace their possible evolutionary development. The ...
Difficult Vomiting Disorders: Therapy. In: Proceedings of the
... Many of the spontaneous vomiting disorders of cats and dogs, particularly those of the primary gastrointestinal tract, are believed to result from activation of the neural pathway. Vomiting associated with primary gastrointestinal tract disease (e.g., inflammation, infection, malignancy, toxicity) r ...
... Many of the spontaneous vomiting disorders of cats and dogs, particularly those of the primary gastrointestinal tract, are believed to result from activation of the neural pathway. Vomiting associated with primary gastrointestinal tract disease (e.g., inflammation, infection, malignancy, toxicity) r ...
Basic concepts of molecular biology and proteins I
... Many rodlike collagen molecules are cross-linked together in the extracellular space to form unextendable collagen fibrils (top) that have the tensile strength of steel. The striping on the collagen fibril is caused by the regular repeating arrangement of the collagen molecules within the fibril. (B ...
... Many rodlike collagen molecules are cross-linked together in the extracellular space to form unextendable collagen fibrils (top) that have the tensile strength of steel. The striping on the collagen fibril is caused by the regular repeating arrangement of the collagen molecules within the fibril. (B ...
PowerPoint to accompany Hole’s Human Anatomy and
... each in Presentation Mode and playing each animation. Most animations will require animation. Most animations will require the latest version of the Flash Player, the latest version of which is available at the Flash Player, which is available at http://get.adobe.com/flashplayer. http://get.adobe.co ...
... each in Presentation Mode and playing each animation. Most animations will require animation. Most animations will require the latest version of the Flash Player, the latest version of which is available at the Flash Player, which is available at http://get.adobe.com/flashplayer. http://get.adobe.co ...
What is cellular Senescence? - Roswell Park Cancer Institute
... IL-1α. This cytokine acts in a juxtacrine manner to bind the cell surface–bound IL-1 receptor, which initiates a signaling cascade that activates transcription factors (NF-κB, C/EBPβ). These transcription factors subsequently stimulate the expression of many secreted (SASP) proteins, including incre ...
... IL-1α. This cytokine acts in a juxtacrine manner to bind the cell surface–bound IL-1 receptor, which initiates a signaling cascade that activates transcription factors (NF-κB, C/EBPβ). These transcription factors subsequently stimulate the expression of many secreted (SASP) proteins, including incre ...
Two Functional a-Tubulin Genes of the Yeast Saccharomyces cerevisiae Encode Divergent Proteins.
... Two a-tubulin genes from the budding yeast Saccharomyces cerevisiae were identified and cloned by cross-species DNA homology. Nucleotide sequencing studies revealed that the two genes, named TUB) and TUB3, encoded gene products of 447 and 445 amino acids, respectively, that are highly homologous to ...
... Two a-tubulin genes from the budding yeast Saccharomyces cerevisiae were identified and cloned by cross-species DNA homology. Nucleotide sequencing studies revealed that the two genes, named TUB) and TUB3, encoded gene products of 447 and 445 amino acids, respectively, that are highly homologous to ...
chapt10_holes_lecture_animation
... each in Presentation Mode and playing each animation. Most animations will require animation. Most animations will require the latest version of the Flash Player, the latest version of which is available at the Flash Player, which is available at http://get.adobe.com/flashplayer. http://get.adobe.co ...
... each in Presentation Mode and playing each animation. Most animations will require animation. Most animations will require the latest version of the Flash Player, the latest version of which is available at the Flash Player, which is available at http://get.adobe.com/flashplayer. http://get.adobe.co ...
Cell Cycle
... attachment, stop signal is received. (b) M checkpoint © 2014 Pearson Education, Inc. ...
... attachment, stop signal is received. (b) M checkpoint © 2014 Pearson Education, Inc. ...
molecular mechanisms of weak organic acid preservative
... magnitude of the ‘flip-flop’ rate, and how these rates are influenced by the membrane composition. The latter refers to membrane protein composition, the length of FA tails and the level of FA saturation (see e.g. [17–19]). Both length and saturation level of the FAs present on membrane lipids deter ...
... magnitude of the ‘flip-flop’ rate, and how these rates are influenced by the membrane composition. The latter refers to membrane protein composition, the length of FA tails and the level of FA saturation (see e.g. [17–19]). Both length and saturation level of the FAs present on membrane lipids deter ...
Extracellular Electrical Fields Direct Wound Healing and Regeneration
... very difficult to alter the expression of genes to rebuild damaged tissue in humans, especially when considering the use of controversial treatments such as gene therapy. A systems-based view of development and regeneration may provide suitable therapeutic alternatives. Complex interactions of multi ...
... very difficult to alter the expression of genes to rebuild damaged tissue in humans, especially when considering the use of controversial treatments such as gene therapy. A systems-based view of development and regeneration may provide suitable therapeutic alternatives. Complex interactions of multi ...
Red Blood Cell Glycophorins
... the genomic structure of GPE is LYCOPHORIN-A (GPA), GPB, GPC, and GPD well-characterized, search for the protein encoded by this constitute a group of red blood cell (RBC) transmemgene has yielded negative results. All the expressed glycophbrane proteins that, although perhaps not widely appreciorin ...
... the genomic structure of GPE is LYCOPHORIN-A (GPA), GPB, GPC, and GPD well-characterized, search for the protein encoded by this constitute a group of red blood cell (RBC) transmemgene has yielded negative results. All the expressed glycophbrane proteins that, although perhaps not widely appreciorin ...
Mesoderm and Endoderm Formation
... Repeat But With Labeled Ectoderm and Endoderm (i.e. lineage tracers) ...
... Repeat But With Labeled Ectoderm and Endoderm (i.e. lineage tracers) ...
Gene expression Most genes are not expressed at a particular time
... Transcription factor binding sites Transcription factors and their binding sites come in several varieties: – Promoters are required for RNA polymerase to bind and begin transcription. The promoter binding site is often a TATAAT ~10bp upstream of the start of transcription. – Activators are proteins ...
... Transcription factor binding sites Transcription factors and their binding sites come in several varieties: – Promoters are required for RNA polymerase to bind and begin transcription. The promoter binding site is often a TATAAT ~10bp upstream of the start of transcription. – Activators are proteins ...
Two dileucine motifs mediate late endosomal/lysosomal targeting of
... DXXLL-type dileucine signals recruit GGA proteins (Golgilocalized, γ -ear-containing, Arf-binding proteins), a different class of monomeric clathrin adaptors functioning at the TGN [13]. Lysosomal membrane proteins can travel from the TGN via a direct route to endosomes and from there to lysosomes, ...
... DXXLL-type dileucine signals recruit GGA proteins (Golgilocalized, γ -ear-containing, Arf-binding proteins), a different class of monomeric clathrin adaptors functioning at the TGN [13]. Lysosomal membrane proteins can travel from the TGN via a direct route to endosomes and from there to lysosomes, ...
Red blood cell glycophorins
... the genomic structure of GPE is LYCOPHORIN-A (GPA), GPB, GPC, and GPD well-characterized, search for the protein encoded by this constitute a group of red blood cell (RBC) transmemgene has yielded negative results. All the expressed glycophbrane proteins that, although perhaps not widely appreciorin ...
... the genomic structure of GPE is LYCOPHORIN-A (GPA), GPB, GPC, and GPD well-characterized, search for the protein encoded by this constitute a group of red blood cell (RBC) transmemgene has yielded negative results. All the expressed glycophbrane proteins that, although perhaps not widely appreciorin ...
Profile
... membrane that is a water filled sack used to store and absorb. FUNCTION: The function of the vacuole is to absorb and store the nutrients the cell needs to survive. MISCELLANEOUS: *gets rid of things that may damage a cell *contains waste products *maintains hydrostatic pressure in the cell *maintai ...
... membrane that is a water filled sack used to store and absorb. FUNCTION: The function of the vacuole is to absorb and store the nutrients the cell needs to survive. MISCELLANEOUS: *gets rid of things that may damage a cell *contains waste products *maintains hydrostatic pressure in the cell *maintai ...
Studies on legume receptors for Nod and Myc symbiotic signals
... japonicus became a model plant used to study these symbioses. It forms determinate nodules with Mesorhizobium loti. As for M. truncatula a set of symbiotic genes has also been identified for L. japonicus (Sato and Tabata, 2006; Madsen et al., 2010). For non-symbiotic studies (plant development, inte ...
... japonicus became a model plant used to study these symbioses. It forms determinate nodules with Mesorhizobium loti. As for M. truncatula a set of symbiotic genes has also been identified for L. japonicus (Sato and Tabata, 2006; Madsen et al., 2010). For non-symbiotic studies (plant development, inte ...
Modulation of T cell signaling by the actin cytoskeleton
... activation involves many spatially and temporally coordinated signaling processes on multiple time and length scales. There are three distinct stages during the activation process: T cell receptor (TCR) triggering, signal persistence and signal termination. A crawling T cell constantly scans the sur ...
... activation involves many spatially and temporally coordinated signaling processes on multiple time and length scales. There are three distinct stages during the activation process: T cell receptor (TCR) triggering, signal persistence and signal termination. A crawling T cell constantly scans the sur ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.