Metabolism of Leukotrienes: The Linear Biosynthetic Pathway
... synthesis of products of the 5-lipoxygenase pathway are shown. LTA4 is the common intermediate in both branches of this pathway. The heavy arrows indicate unidirectional steps by which LTB4 and LTC4 are exported from cells. FLAP denotes the 5-lipoxygenase activating protein. (From Lewis et al. (2).) ...
... synthesis of products of the 5-lipoxygenase pathway are shown. LTA4 is the common intermediate in both branches of this pathway. The heavy arrows indicate unidirectional steps by which LTB4 and LTC4 are exported from cells. FLAP denotes the 5-lipoxygenase activating protein. (From Lewis et al. (2).) ...
review - Saudi Medical Journal
... Salmonella enterica can produce both localized enteritis and disseminated systemic disease in humans and other vertebrates (28). Salmonella uses specialised virulence mechanisms to induce host cell death during infection. It produces one set of virulence proteins to promote invasion (of the intestin ...
... Salmonella enterica can produce both localized enteritis and disseminated systemic disease in humans and other vertebrates (28). Salmonella uses specialised virulence mechanisms to induce host cell death during infection. It produces one set of virulence proteins to promote invasion (of the intestin ...
The importance of the five phosphoribosyl
... and PRS3, respectively, were created by transforming YN9796 with the PCR products obtained from YN97-141 and YN96-52 using primers flanking the disrupted PRS2 and PRS3 loci (Carter et al., 1997). YN98-12 and YN98-14 were created by the short flanking homology method (Wach et al., 1994) using appropr ...
... and PRS3, respectively, were created by transforming YN9796 with the PCR products obtained from YN97-141 and YN96-52 using primers flanking the disrupted PRS2 and PRS3 loci (Carter et al., 1997). YN98-12 and YN98-14 were created by the short flanking homology method (Wach et al., 1994) using appropr ...
Delivering of Proteins to the Plant Vacuole—An Update
... positive information from the protein. In mammals, the signal to transport proteins to the lysosome is the addition of a mannose 6-phosphate residue during the passage through the Golgi complex, while in plant cells, the vacuolar sorting is part of the peptide sequence [5,27]. Several vacuolar sorti ...
... positive information from the protein. In mammals, the signal to transport proteins to the lysosome is the addition of a mannose 6-phosphate residue during the passage through the Golgi complex, while in plant cells, the vacuolar sorting is part of the peptide sequence [5,27]. Several vacuolar sorti ...
Chapter 15 Control of Enzyme Activity
... Covalent modification • A faster means to control rate—don’t need to completely synthesize a new protein • Requires a reaction to activate, another to de-activate. • For example, phosphorylationdephosphorylation (See Fig. 15.2) ...
... Covalent modification • A faster means to control rate—don’t need to completely synthesize a new protein • Requires a reaction to activate, another to de-activate. • For example, phosphorylationdephosphorylation (See Fig. 15.2) ...
Overview of Protein Structure • The three
... The interior of proteins is hydrophobic, consisting primarily of aliphatic residues that are in intimate contact so as to exclude water. It is thought that exclusion of water from the hydrophobic protein interior is one of the principle forces stabilizing the native structure of proteins. However, t ...
... The interior of proteins is hydrophobic, consisting primarily of aliphatic residues that are in intimate contact so as to exclude water. It is thought that exclusion of water from the hydrophobic protein interior is one of the principle forces stabilizing the native structure of proteins. However, t ...
ppt - Chair of Computational Biology
... Cyclic adenosine monophosphate (cAMP) is a second messenger that is important in many biological processes. cAMP is derived from ATP and used for intracellular signal transduction in many different organisms, conveying the cAMP dependent pathway. In humans, cyclic AMP works by activating cAMP-depend ...
... Cyclic adenosine monophosphate (cAMP) is a second messenger that is important in many biological processes. cAMP is derived from ATP and used for intracellular signal transduction in many different organisms, conveying the cAMP dependent pathway. In humans, cyclic AMP works by activating cAMP-depend ...
Presentation (PowerPoint File)
... resonant element [in the organ of Corti] would become self-oscillatory, and oscillations would build up [to] a level where linearity was not preserved.” ...
... resonant element [in the organ of Corti] would become self-oscillatory, and oscillations would build up [to] a level where linearity was not preserved.” ...
Contribution of the Plasma Membrane and Central Vacuole in the
... The GFP(S65T)-AtVam3p/T-DNA vector and the plasmids pKY101 and pMAT (gamma-VM23)-sGFP were used for Agrobacterium-mediated transformation of tobacco cells (Matsuoka and Nakamura 1991) in order to prepare cells expressing GFP-AtVam3p, sporamin-GFP and gamma-VM23GFP fusion proteins, respectively. In m ...
... The GFP(S65T)-AtVam3p/T-DNA vector and the plasmids pKY101 and pMAT (gamma-VM23)-sGFP were used for Agrobacterium-mediated transformation of tobacco cells (Matsuoka and Nakamura 1991) in order to prepare cells expressing GFP-AtVam3p, sporamin-GFP and gamma-VM23GFP fusion proteins, respectively. In m ...
Novel adenosine and cAMP signalling pathways in migrating glial
... The endogenous purine ribonucleoside adenosine is an important modulator of neuronal activities, including viability, excitability, synaptic transmission, neuron–glia communication and neuroprotection [1–3]. Moreover, alteration of adenosine receptors density and functions has been associated with s ...
... The endogenous purine ribonucleoside adenosine is an important modulator of neuronal activities, including viability, excitability, synaptic transmission, neuron–glia communication and neuroprotection [1–3]. Moreover, alteration of adenosine receptors density and functions has been associated with s ...
Characterization of Organelles in the Vacuolar
... The receptors are a type I integral membrane protein with epidermal growth factor (EGF)-like motifs in the lumenal domain. The lumenal domains of PV72 (our unpublished data) and BP-80 (Paris et al. 1997) are involved in ligand binding, while the cytosolic tail of BP-80 is reported to be involved in ...
... The receptors are a type I integral membrane protein with epidermal growth factor (EGF)-like motifs in the lumenal domain. The lumenal domains of PV72 (our unpublished data) and BP-80 (Paris et al. 1997) are involved in ligand binding, while the cytosolic tail of BP-80 is reported to be involved in ...
Delivery of a Secreted Soluble Protein to the Vacuole via a
... For soluble proteins, it has been shown that the critical sorting event occurs in the TGN, and that secretion is a default destination, whereas transport to the vacuole requires positive sorting information. In the yeast Saccharomyces cerevisiae, the vacuolar membrane appears to be the default desti ...
... For soluble proteins, it has been shown that the critical sorting event occurs in the TGN, and that secretion is a default destination, whereas transport to the vacuole requires positive sorting information. In the yeast Saccharomyces cerevisiae, the vacuolar membrane appears to be the default desti ...
HIF-2α phosphorylation by CK1δ promotes erythropoietin secretion
... Casein kinase 1δ supports HIF-2 transcriptional activity and stimulates EPO secretion To investigate the involvement of CK1δ in the regulation of HIF-2α, its expression was suppressed in Huh7 cells by small interfering RNA (siRNA)-mediated silencing. Treatment of cells with CK1δ siRNA under hypoxic ...
... Casein kinase 1δ supports HIF-2 transcriptional activity and stimulates EPO secretion To investigate the involvement of CK1δ in the regulation of HIF-2α, its expression was suppressed in Huh7 cells by small interfering RNA (siRNA)-mediated silencing. Treatment of cells with CK1δ siRNA under hypoxic ...
Ch. 3 - SBCC Biological Sciences Department
... bilayer. However, the bilayer is impermeable to watersoluble molecules, which include amino acids, sugars, proteins, nucleic acids, and various ions. Cholesterol molecules embedded in the cell membrane’s interior help make the membrane less permeable to water- soluble substances, while their rigid ...
... bilayer. However, the bilayer is impermeable to watersoluble molecules, which include amino acids, sugars, proteins, nucleic acids, and various ions. Cholesterol molecules embedded in the cell membrane’s interior help make the membrane less permeable to water- soluble substances, while their rigid ...
chapter 23
... Fats and oils make up the most common group of lipids in your diet. These molecules are known as triglycerides. They are formed by condensation reactions in which three fatty acid molecules bond to one glycerol (a type of alcohol) molecule. Fats, such as butter and lard, come from animals, while oil ...
... Fats and oils make up the most common group of lipids in your diet. These molecules are known as triglycerides. They are formed by condensation reactions in which three fatty acid molecules bond to one glycerol (a type of alcohol) molecule. Fats, such as butter and lard, come from animals, while oil ...
lysosomes, transport vesicles, plasma membrane
... Which of the following is not an argument for the theory that mitochondria and chloroplasts evolved from prokaryotic endosymbionts? A. Mitochondria and chloroplasts have double membranes. B. Mitochondria and chloroplasts have their own ribosomes. C. Mitochondria and chloroplasts have their own DNA. ...
... Which of the following is not an argument for the theory that mitochondria and chloroplasts evolved from prokaryotic endosymbionts? A. Mitochondria and chloroplasts have double membranes. B. Mitochondria and chloroplasts have their own ribosomes. C. Mitochondria and chloroplasts have their own DNA. ...
Characterization of Ubiquitin/Proteasome
... I have often been quoted as saying, “my Honors thesis has changed my life.” This is a statement by which I resolutely stand. The expense in physical and mental strain that it has cost me are fully validated with the fulfillment and reward with which I have been repaid. From the increased level of co ...
... I have often been quoted as saying, “my Honors thesis has changed my life.” This is a statement by which I resolutely stand. The expense in physical and mental strain that it has cost me are fully validated with the fulfillment and reward with which I have been repaid. From the increased level of co ...
Regulation of macronutrient transport
... respond to different environmental situations, that is, progressive depletion of the nutrient in the soil or resupply after a period of scarcity. In both cases the regulatory events result in high expression levels of specific transporters under conditions that require their function as high-affinit ...
... respond to different environmental situations, that is, progressive depletion of the nutrient in the soil or resupply after a period of scarcity. In both cases the regulatory events result in high expression levels of specific transporters under conditions that require their function as high-affinit ...
Endoplasmic Reticulum Stress and Pancreatic Cancer
... Pancreatic cancer has a very high rate of mortality because there are no effective therapies for this type of tumor at present. Pancreatic cancer often has poor prognosis, even when diagnosed early. Detection of pancreatic cancer in the early stages is very rare, which is a major reason why it is a ...
... Pancreatic cancer has a very high rate of mortality because there are no effective therapies for this type of tumor at present. Pancreatic cancer often has poor prognosis, even when diagnosed early. Detection of pancreatic cancer in the early stages is very rare, which is a major reason why it is a ...
Melanocytes and melanogenesis - Our Dermatology Online journal
... The Tyrosine, under the influence of Tyrosinase and CU 2+ forms DOPA and then Dopaquinone. This Dopaquinone with the help of Cystathione or Cysteine, forms Cysteine-L-Dopa which further forms pheomelanin. When Cysteine is depleted, the Dopaquinone forms Leucodopachrome which ultimately forms eumelan ...
... The Tyrosine, under the influence of Tyrosinase and CU 2+ forms DOPA and then Dopaquinone. This Dopaquinone with the help of Cystathione or Cysteine, forms Cysteine-L-Dopa which further forms pheomelanin. When Cysteine is depleted, the Dopaquinone forms Leucodopachrome which ultimately forms eumelan ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.