What's a cerebellar circuit doing in the auditory system?
... Hearing enables vertebrate animals to know what goes on around them even when they cannot see. Localizing the position of sound sources is thus an important biological function of the auditory system. Interaural time and intensity differences are used by reptiles, birds and mammals for localizing so ...
... Hearing enables vertebrate animals to know what goes on around them even when they cannot see. Localizing the position of sound sources is thus an important biological function of the auditory system. Interaural time and intensity differences are used by reptiles, birds and mammals for localizing so ...
Solubilization and Analysis of Mannoprotein Molecules from The
... periplasmic invertase molecules. Besides this, the fact that the activity of lytic enzymes on glucan for the purpose of obtaining protoplasts is facilitated by previous treatment of intact cells with proteases or reducing agents (Vrganskh et ul., 1977; Santos et ul., 1981)points to an internal locat ...
... periplasmic invertase molecules. Besides this, the fact that the activity of lytic enzymes on glucan for the purpose of obtaining protoplasts is facilitated by previous treatment of intact cells with proteases or reducing agents (Vrganskh et ul., 1977; Santos et ul., 1981)points to an internal locat ...
Role of Slitrk Family Members in
... The development of the nervous system is an extremely complex process where gene expression is tightly regulated, both spatially and temporally. Any gene disruption during neurodevelopment, from the complete non-transcription of the gene to a single nucleotide mutation, has the potential to lead to ...
... The development of the nervous system is an extremely complex process where gene expression is tightly regulated, both spatially and temporally. Any gene disruption during neurodevelopment, from the complete non-transcription of the gene to a single nucleotide mutation, has the potential to lead to ...
Cardiovascular Effects of Androgens
... DNA binding domain (DBD), and a COOH-terminal hormone-binding domain (HBD) (Figure 1). The COOH-terminus contains an additional activation domain and a hinge region connecting the HBD and the DBD. Upon ligand binding, the nuclear receptors translocate to the nucleus where they dimerize and bind to r ...
... DNA binding domain (DBD), and a COOH-terminal hormone-binding domain (HBD) (Figure 1). The COOH-terminus contains an additional activation domain and a hinge region connecting the HBD and the DBD. Upon ligand binding, the nuclear receptors translocate to the nucleus where they dimerize and bind to r ...
nerve local potentials and action potentials - Peer
... $300: This is a long process that carries a nerve impulse away from the cell body to form a synapse with another cell. $400: To speed conduction, many axons are covered in this. $500: These small projections are the receiving part of the neuron. Category 2: The Local News $100: This is where local p ...
... $300: This is a long process that carries a nerve impulse away from the cell body to form a synapse with another cell. $400: To speed conduction, many axons are covered in this. $500: These small projections are the receiving part of the neuron. Category 2: The Local News $100: This is where local p ...
Diefenbach, A., and D.H. Raulet. 2002. The innate immune response to tumors and its role in the induction of T cell immunity. Immunological Reviews 188:9-21.
... with TNF receptor family members on target cells. One member of the family, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), is expressed in vivo by activated NK cells. In vivo induction of TRAIL on NK cells correlated with TRAIL-mediated antimetastatic effects against various transf ...
... with TNF receptor family members on target cells. One member of the family, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), is expressed in vivo by activated NK cells. In vivo induction of TRAIL on NK cells correlated with TRAIL-mediated antimetastatic effects against various transf ...
The Connexin46 mutant (V44M)
... to junctional plaques. Since Cx46 V44M mutant forms smaller and less junctional plaques than wt-Cx46, this is possibly owing to the decreased formation of junctional plaques or because of the mutant somehow may have weaker interaction with those from neighboring cells as well. The gap junction plaqu ...
... to junctional plaques. Since Cx46 V44M mutant forms smaller and less junctional plaques than wt-Cx46, this is possibly owing to the decreased formation of junctional plaques or because of the mutant somehow may have weaker interaction with those from neighboring cells as well. The gap junction plaqu ...
Alfalfa Cyclins: Differential Expression during the Cell
... embryos with redundant oligonucleotides encoding the conserved amino acid sequences K-Y-E-E-M(I)-Y-Pfor the cyclin A and B type and I-L-V(I)-D-W-L-Vfor the cyclin B class (see Methods for the nucleotide sequences). Positive colonies were isolated and rescreened according to the method of Hanks et al ...
... embryos with redundant oligonucleotides encoding the conserved amino acid sequences K-Y-E-E-M(I)-Y-Pfor the cyclin A and B type and I-L-V(I)-D-W-L-Vfor the cyclin B class (see Methods for the nucleotide sequences). Positive colonies were isolated and rescreened according to the method of Hanks et al ...
Xror2 modulates convergent extension
... One of the organizer-specific transcription factors is the LIM class homeodomain protein Xlim-1 (Taira et al., 1992). The LIM domain mutant of Xlim-1, named Xlim-1/3m, or a complex of Xlim-1 and the LIM domain-binding protein Ldb1, appears to behave as an activated form of Xlim-1. Activated forms of ...
... One of the organizer-specific transcription factors is the LIM class homeodomain protein Xlim-1 (Taira et al., 1992). The LIM domain mutant of Xlim-1, named Xlim-1/3m, or a complex of Xlim-1 and the LIM domain-binding protein Ldb1, appears to behave as an activated form of Xlim-1. Activated forms of ...
Preview Sample 2
... 63. Mitochondria are responsible for the synthesis of most of the energy rich ATP molecules used by human cells. TRUE ...
... 63. Mitochondria are responsible for the synthesis of most of the energy rich ATP molecules used by human cells. TRUE ...
Exchange protein directly activated by cAMP (EPAC) interacts with
... intracellular levels of the ubiquitous second-messenger cAMP [1]. These include immunomodulators, neurotransmitters and hormones, which typically activate the seven-transmembrane domain class of G-protein-coupled receptors [1]. Ligand binding causes activation of heterotrimeric G-proteins that stimu ...
... intracellular levels of the ubiquitous second-messenger cAMP [1]. These include immunomodulators, neurotransmitters and hormones, which typically activate the seven-transmembrane domain class of G-protein-coupled receptors [1]. Ligand binding causes activation of heterotrimeric G-proteins that stimu ...
Strategies for the Allocation of Resources under Sulfur Limitation in
... sufficient (48 mM, black bars) or limiting sulfate (6 M, white bars) concentration. OAS, O-Acetyl-Ser. The values shown are the means ⫾ SD of five extractions with two replicates each. ...
... sufficient (48 mM, black bars) or limiting sulfate (6 M, white bars) concentration. OAS, O-Acetyl-Ser. The values shown are the means ⫾ SD of five extractions with two replicates each. ...
N-glycosylation and microtubule integrity are involved in apical
... network to their appropriate plasma membrane domain, others are first delivered to the opposing membrane surface before undergoing transcytosis to their ultimate destination (11). The particular transport pathway by which a given protein reaches the plasma membrane is dependent upon the individual p ...
... network to their appropriate plasma membrane domain, others are first delivered to the opposing membrane surface before undergoing transcytosis to their ultimate destination (11). The particular transport pathway by which a given protein reaches the plasma membrane is dependent upon the individual p ...
TYK2 (JTK1), Active TYK2 (JTK1), Active
... Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. Product shipped ...
... Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. Product shipped ...
Plant stem cells: divergent pathways and common themes in shoots
... Genetic evidence suggests that stem cells in plants, as in animals, have a specialized chromatin structure. This may reflect their capacity for a variety of gene-expression programs, as well as their ability to divide repeatedly without either differentiation or senescence. Components of the chromat ...
... Genetic evidence suggests that stem cells in plants, as in animals, have a specialized chromatin structure. This may reflect their capacity for a variety of gene-expression programs, as well as their ability to divide repeatedly without either differentiation or senescence. Components of the chromat ...
BioVision
... Centrifuge the vial prior to opening. Reconstitute in sterile ddH2O to a concentration≥ 100 µg/ml. This solution can then be diluted into other aqueous buffers. STORAGE CONDITIONS: The lyophilized protein is best-stored desiccated at -20°C. Reconstituted mouse LIF should be stored at 4°C for 2-7 day ...
... Centrifuge the vial prior to opening. Reconstitute in sterile ddH2O to a concentration≥ 100 µg/ml. This solution can then be diluted into other aqueous buffers. STORAGE CONDITIONS: The lyophilized protein is best-stored desiccated at -20°C. Reconstituted mouse LIF should be stored at 4°C for 2-7 day ...
Nuclear Envelope Breakdown Proceeds by
... obtain a direct space-time correlation of two proteins in the same dividing cell (Gerlich et al., 2001). To precisely determine the time point of nuclear permeabilization, we measured the influx of large cytoplasmic molecules or the appearance of the first discontinuity in the NE. These events serve ...
... obtain a direct space-time correlation of two proteins in the same dividing cell (Gerlich et al., 2001). To precisely determine the time point of nuclear permeabilization, we measured the influx of large cytoplasmic molecules or the appearance of the first discontinuity in the NE. These events serve ...
Transcriptional regulation of the H-ras1 proto
... mutual antagonism between activation by AP-1 and glucocorticoid receptors at target genes that contain recognition sites for both factors, via protein-protein interactions (Yang-Yen et al, 1990). Finally, the NF-I (CTF) nuclear factor binds the CCAAT element (CAAT box) and is involved in both gene t ...
... mutual antagonism between activation by AP-1 and glucocorticoid receptors at target genes that contain recognition sites for both factors, via protein-protein interactions (Yang-Yen et al, 1990). Finally, the NF-I (CTF) nuclear factor binds the CCAAT element (CAAT box) and is involved in both gene t ...
Crossing borders to bind proteins—a new concept in protein
... molecule consists of a small organic molecule or peptide that is linked with or without an interconnecting spacer to a 42-residue polypeptide selected from a set of only sixteen sequences (Fig. 1) [12]. The small molecule must bind to the protein but only modest affinity is required. Conjugation to ...
... molecule consists of a small organic molecule or peptide that is linked with or without an interconnecting spacer to a 42-residue polypeptide selected from a set of only sixteen sequences (Fig. 1) [12]. The small molecule must bind to the protein but only modest affinity is required. Conjugation to ...
The change of HERS cell number and gene expression profile by
... 1 protein have shorter roots [2]. Furthermore, the molar roots of sulf1/sulf2 double knockout mice were short [3]. Thus, factors regulating root length have remained unknown. Hertwig’s epithelial root sheath (HERS) is a bi-layered cell sheath formed by the inner enamel epithelium (IEE) and outer ena ...
... 1 protein have shorter roots [2]. Furthermore, the molar roots of sulf1/sulf2 double knockout mice were short [3]. Thus, factors regulating root length have remained unknown. Hertwig’s epithelial root sheath (HERS) is a bi-layered cell sheath formed by the inner enamel epithelium (IEE) and outer ena ...
Cell Respiration RG
... 16. Complete the summary diagram of cellular respiration. You are responsible for these #’s and locations! ...
... 16. Complete the summary diagram of cellular respiration. You are responsible for these #’s and locations! ...
The added value of single-cell gene expression
... cell population studies is due to the large number of cells analyzed, which averages out the large natural variation among individual cells. However, the averaging also eliminates much of the differences in expression contributed by subpopulations. There is also risk that the reference genes selecte ...
... cell population studies is due to the large number of cells analyzed, which averages out the large natural variation among individual cells. However, the averaging also eliminates much of the differences in expression contributed by subpopulations. There is also risk that the reference genes selecte ...
Pergamon - Anatomical Neuropharmacology Unit
... ~:Department of Neurology, Emory University School Medicine, Atlanta, GA, U.S.A. Abstract--The modulatory actions of dopamine on the flow of cortical information through the basal ganglia are mediated mainly through two subtypes of receptors, the D 1 and D e receptors. In order to examine the precis ...
... ~:Department of Neurology, Emory University School Medicine, Atlanta, GA, U.S.A. Abstract--The modulatory actions of dopamine on the flow of cortical information through the basal ganglia are mediated mainly through two subtypes of receptors, the D 1 and D e receptors. In order to examine the precis ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.