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Supplemental Methods, Figures 1-5 and Table 1
Supplemental Methods, Figures 1-5 and Table 1

... Transgenic Core, Washington University). One initial founder chimaera was chosen due to high degree chimerism as assessed by coat color and subsequently backcrossed onto a pure albino C57BL/6 background (N6 as determined by speed congenics). Polymerase chain reaction genotyping ...
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Cell encapsulation



Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.
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