Compartmentalisation of Rho regulators directs cell
... Evidence that the spatial and temporal control of small RhoGTPase function must be correlated with the activity of Rho regulators during tissue morphogenesis is suggested from studies on cell shape changes occurring during gastrulation and neurulation. In Drosophila gastrulation, a secreted factor F ...
... Evidence that the spatial and temporal control of small RhoGTPase function must be correlated with the activity of Rho regulators during tissue morphogenesis is suggested from studies on cell shape changes occurring during gastrulation and neurulation. In Drosophila gastrulation, a secreted factor F ...
IGF signaling directs ventricular cardiomyocyte
... epicardial cells were allowed to continue to grow until reaching near confluence (Chen et al., 2002). The cells were then trypsinized and replated at low to moderate density; under these conditions, most cells differentiate into postmitotic fibroblastic-type cells that are easily recognized. Small c ...
... epicardial cells were allowed to continue to grow until reaching near confluence (Chen et al., 2002). The cells were then trypsinized and replated at low to moderate density; under these conditions, most cells differentiate into postmitotic fibroblastic-type cells that are easily recognized. Small c ...
POM-POM2/CELLULOSE SYNTHASE
... and growth. The expansion is driven by vacuolar turgor pressure and is restricted by a strong, yet flexible, cell wall that permits directional cell growth. The cell wall is mainly constituted of polysaccharides, such as cellulose, hemicelluloses, and pectins, and highly glycosylated proteins (Somer ...
... and growth. The expansion is driven by vacuolar turgor pressure and is restricted by a strong, yet flexible, cell wall that permits directional cell growth. The cell wall is mainly constituted of polysaccharides, such as cellulose, hemicelluloses, and pectins, and highly glycosylated proteins (Somer ...
Visualization of the moonlighting protein CD26DPPIV - UvA-DARE
... produce maximal amounts of colored or fluorescent final reaction product. These concentrations are usually high so that the maximal velocity of the enzyme (Vmax) is obtained. However, these high substrate concentrations are seldom present in vivo. Moreover, the affinity of an enzyme for its substrat ...
... produce maximal amounts of colored or fluorescent final reaction product. These concentrations are usually high so that the maximal velocity of the enzyme (Vmax) is obtained. However, these high substrate concentrations are seldom present in vivo. Moreover, the affinity of an enzyme for its substrat ...
- Wiley Online Library
... Hunt, 2005; Rieffel et al., 2014). Nevertheless, this remains a timeintensive baculovirus based system without direct in-line analysis of the expressed protein. A second option is the so called plasmid based transient and transactivation screening method (Radner et al., 2012). Here, the rather weak ...
... Hunt, 2005; Rieffel et al., 2014). Nevertheless, this remains a timeintensive baculovirus based system without direct in-line analysis of the expressed protein. A second option is the so called plasmid based transient and transactivation screening method (Radner et al., 2012). Here, the rather weak ...
Pulmonary immune cells in health and disease: lymphocytes
... it has been demonstrated that a small subset of T-cells expresses y/o heterodimers [ 15]. Using WT31 MoAb that recognizes the w~ TCR, we recently demonstrated that the majority ofBAL T-cells from healthy individuals eoexpress the TCR wp [13]. By contrast, only a few nonnallung cells (about 5%) stain ...
... it has been demonstrated that a small subset of T-cells expresses y/o heterodimers [ 15]. Using WT31 MoAb that recognizes the w~ TCR, we recently demonstrated that the majority ofBAL T-cells from healthy individuals eoexpress the TCR wp [13]. By contrast, only a few nonnallung cells (about 5%) stain ...
Multiscale View of Cytoskeletal Mechanoregulation of Cell and
... components related to the extracellular matrix (ECM) of higher metazoans, including collagen, and fibronectin-like protein (Labat-Robert et al. 1981). Naturally, in higher metazoa the repertoire of ECM proteins is considerably larger than that of sponges, reflecting the increasing complexity of tiss ...
... components related to the extracellular matrix (ECM) of higher metazoans, including collagen, and fibronectin-like protein (Labat-Robert et al. 1981). Naturally, in higher metazoa the repertoire of ECM proteins is considerably larger than that of sponges, reflecting the increasing complexity of tiss ...
Epithelial differentiation and intercellular junction
... ing zonular (Fleming et al., 1989). In the blastocyst, trophectoderm cells are bordered by a prominant belt-like ZO1 distribution (Fig. 2). Immunoblotting and cellular experiments involving biosynthetic inhibitors suggest that ZO-1 is first synthesised from the late 4-cell/early 8-cell stage, althou ...
... ing zonular (Fleming et al., 1989). In the blastocyst, trophectoderm cells are bordered by a prominant belt-like ZO1 distribution (Fig. 2). Immunoblotting and cellular experiments involving biosynthetic inhibitors suggest that ZO-1 is first synthesised from the late 4-cell/early 8-cell stage, althou ...
Cell Injury
... liquefaction necrosis • Primarily found in the center of tubercles • Inability to digest and remove material from center of granuloma ...
... liquefaction necrosis • Primarily found in the center of tubercles • Inability to digest and remove material from center of granuloma ...
Hormones
... structures (called ducts) out of the body or directly into the digestive system. Exocrine glands include those that release sweat, tears, and digestive enzymes. ...
... structures (called ducts) out of the body or directly into the digestive system. Exocrine glands include those that release sweat, tears, and digestive enzymes. ...
Simian Virus 40 Large T Antigen and p53 Are
... immunoprecipitation strongly suggested that the complex existed prior to cell lysis. In a second experiment, we used partially purified tubulin as a specific competitor for the M, 56,000 component of the complex. The tubulin was prepared by two cycles of repolymerization from suspension human lung c ...
... immunoprecipitation strongly suggested that the complex existed prior to cell lysis. In a second experiment, we used partially purified tubulin as a specific competitor for the M, 56,000 component of the complex. The tubulin was prepared by two cycles of repolymerization from suspension human lung c ...
PDF only - at www.arxiv.org.
... 1.1 The in vitro study of the effect of topography on nerve cells The role of soluble (bio)chemical signals in cell shape, cell adhesion, differentiation and axon guidance, is well established [1]. In addition to the biochemical signals, there is increasing evidence that the physical parameters (e.g ...
... 1.1 The in vitro study of the effect of topography on nerve cells The role of soluble (bio)chemical signals in cell shape, cell adhesion, differentiation and axon guidance, is well established [1]. In addition to the biochemical signals, there is increasing evidence that the physical parameters (e.g ...
Correlating single cell motility with population growth dynamics
... the bulk fluid volumes handled in bioreactors, motility of individual bacterial cells is not considered to influence bioreactor operations. However, with increasing interest in localized fluid flow inside reactors, along with the bulk flow, it is important to ask the question whether individual moti ...
... the bulk fluid volumes handled in bioreactors, motility of individual bacterial cells is not considered to influence bioreactor operations. However, with increasing interest in localized fluid flow inside reactors, along with the bulk flow, it is important to ask the question whether individual moti ...
1 Sporulation, bacterial cell envelopes, and the origin of life Elitza I
... layer is extended by the synthesis of new PG at the leading edges of engulfing membranes as they progress around the immature spore30. At the end of engulfment, a thin layer of PG is found between the two spore membranes and likely acts as a foundation for the synthesis of the spore cortex (thick pr ...
... layer is extended by the synthesis of new PG at the leading edges of engulfing membranes as they progress around the immature spore30. At the end of engulfment, a thin layer of PG is found between the two spore membranes and likely acts as a foundation for the synthesis of the spore cortex (thick pr ...
The role of Mitogen Activated Protein Kinase (MAPK) - UiO
... secreted from adipocytes and released into the blood leptin acts on many tissues and induces effects on muscles, bones, pancreatic beta cells, immune cells and also several other tissues and organs. However, the most important effect is believed to be on the Central Nervous System (CNS). Leptin is t ...
... secreted from adipocytes and released into the blood leptin acts on many tissues and induces effects on muscles, bones, pancreatic beta cells, immune cells and also several other tissues and organs. However, the most important effect is believed to be on the Central Nervous System (CNS). Leptin is t ...
Physiological Structure and Single
... That complex aquatic bacterial assemblages harbor a wide range of single-cell metabolic activities as well as of physiological states is neither surprising nor much contested nowadays. Yet, in spite of the simplicity of this basic premise, the actual description and quantification of this metabolic ...
... That complex aquatic bacterial assemblages harbor a wide range of single-cell metabolic activities as well as of physiological states is neither surprising nor much contested nowadays. Yet, in spite of the simplicity of this basic premise, the actual description and quantification of this metabolic ...
Translocation of Magnaporthe oryzae Effectors into
... Knowledge remains limited about how fungal pathogens that colonize living plant cells translocate effector proteins inside host cells to regulate cellular processes and neutralize defense responses. To cause the globally important rice blast disease, specialized invasive hyphae (IH) invade successiv ...
... Knowledge remains limited about how fungal pathogens that colonize living plant cells translocate effector proteins inside host cells to regulate cellular processes and neutralize defense responses. To cause the globally important rice blast disease, specialized invasive hyphae (IH) invade successiv ...
Cell-cycle regulation
... The exclamation figure denotes the active kinase complex, the large arrow indicates time. ...
... The exclamation figure denotes the active kinase complex, the large arrow indicates time. ...
Towards a unifying model for the metaphase
... >95% similar within the same locus (Arn et al, 1989; Warburton and Willard, 1996). The direction of the a-satellite sequences does not seem to be important for their function: isochromosomes act as normal. Other structural sequences do not seem to be necessary either, as various rearrangements also ...
... >95% similar within the same locus (Arn et al, 1989; Warburton and Willard, 1996). The direction of the a-satellite sequences does not seem to be important for their function: isochromosomes act as normal. Other structural sequences do not seem to be necessary either, as various rearrangements also ...
Movement and Remodeling of the Endoplasmic
... whose movement they effect, thus indicating titration of accessory factors or low levels of organelle binding. Here, analytical software has been developed to address questions of whether the increased movement and dispersion that characterize plant organelles, relative to organelles of animal cells ...
... whose movement they effect, thus indicating titration of accessory factors or low levels of organelle binding. Here, analytical software has been developed to address questions of whether the increased movement and dispersion that characterize plant organelles, relative to organelles of animal cells ...
PDF
... for surviving in the dry aerial environment. A detailed understanding of the structure, composition, and development of moss cell walls can contribute to our understanding of not only the evolution of overall cell wall complexity, but also the differences that have evolved in response to selection f ...
... for surviving in the dry aerial environment. A detailed understanding of the structure, composition, and development of moss cell walls can contribute to our understanding of not only the evolution of overall cell wall complexity, but also the differences that have evolved in response to selection f ...
Cancer Therapy – Opioid growth factors E
... Gemcitabine is the standard of care for advanced pancreatic neoplasia, and exerts its effect through inhibition of DNA synthesis. However, gemcitabine has limited survival benefits. Opioid growth factor (OGF) is an autocrine-produced peptide that interacts with the nuclear receptor, OGFr, to inhibi ...
... Gemcitabine is the standard of care for advanced pancreatic neoplasia, and exerts its effect through inhibition of DNA synthesis. However, gemcitabine has limited survival benefits. Opioid growth factor (OGF) is an autocrine-produced peptide that interacts with the nuclear receptor, OGFr, to inhibi ...
necessary amino acids and vitamins
... combinations of other amino acids permitted sustained HEDLF growth (Litwin, 1974), it must be assumed that the combinations given above satisfy some minimum necessary requirement of these cells. Eagle, Piez & Levy (1961) have shown that cells in vitro have the ability to concentrate many fold the am ...
... combinations of other amino acids permitted sustained HEDLF growth (Litwin, 1974), it must be assumed that the combinations given above satisfy some minimum necessary requirement of these cells. Eagle, Piez & Levy (1961) have shown that cells in vitro have the ability to concentrate many fold the am ...
Mitotic Block Induced in HeLa Cells by Low Concentrations of
... for 20 h and at 24, 48, and 72 h after removal of the drug. As shown in Fig. 2A, incubation with paclitaxel for 20 h inhibited cell prolifer ation in a concentration-dependent manner. Cell proliferation was inhibited in parallel with inhibition of mitosis (Fig. 1). For example, 3 nM paclitaxel induc ...
... for 20 h and at 24, 48, and 72 h after removal of the drug. As shown in Fig. 2A, incubation with paclitaxel for 20 h inhibited cell prolifer ation in a concentration-dependent manner. Cell proliferation was inhibited in parallel with inhibition of mitosis (Fig. 1). For example, 3 nM paclitaxel induc ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.