• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Traditional (historical) Breeding
Traditional (historical) Breeding

... Basic Genetics and Cytogenetics • Inheritance: May be defined as a tendency of parents to generate offspring with similar characteristics. • Variation: May be defined as every environmental or germinal differences between organisms related by ascendance. It can be due differences on the environment ...
Molecular Genetics of Viruses
Molecular Genetics of Viruses

... 2. Promoter region- RNA polymerase attaches to this region to begin transcription. 3. Operator region- can block the action of the RNA polymerase if the region is occupied by a repressor protein. 4. Structural genes- DNA sequences that code for several related enzymes that direct the production of s ...
Webquests_files/Genes and DNA SWQ
Webquests_files/Genes and DNA SWQ

... What is the relationship between DNA genes and proteins???? ...
Key for Practice Exam 4
Key for Practice Exam 4

... Key for Practice Exam 4 1. Match the terms with their definition. a) contains DNA from 2 different sources_ Recombinant DNA molecules ________ b) using recombinant DNA technology to manipulate genes for genetic analysis for developing products or other applications___ Genetic Engineering ____ c) gen ...
b, PKU
b, PKU

... Alleles found on the same ch¡omosomes a. are dominantb- are never sçarated by recombinationc. are linked. d- contain repetitive DNA. Colorblindness is more common in males thal h females i¡ecause fathers pass the allele for colorbli¡dness to their sons only. the allele for colorblindness is located ...
ch 4 notes
ch 4 notes

... This gene has 2 alleles. If you have one, you are malaria resistant and not highly anemic. If you have both, you are sickle-cell anemic One inherited from each parent, thus the 1:4 ratio observed in local populations A relationship has been documented between possession of one S gene and higher surv ...
PowerPoint 簡報
PowerPoint 簡報

... Genetic modification (GM) involves copying the genes which govern a particular characteristic from one organism, and transferring them to another. ...
Nuclear DNA in Molecular systematics Nuclear DNA is double
Nuclear DNA in Molecular systematics Nuclear DNA is double

... external transcribed region; ITS = internal transcribed region. ...
Ross - Tree Improvement Program
Ross - Tree Improvement Program

... region of DNA that affects a trait of interest • “Gene” means a region of DNA that encodes some product needed by the cell. • “Regulatory sequences” control expression of genes, but are not always near the genes they control ...
What are the “Characteristics of Life”
What are the “Characteristics of Life”

... report that lin-4 and lin-14 also regulate life span in the adult. Reducing the activity of lin-4 shortened life span and accelerated tissue aging, whereas overexpressing lin-4 or reducing the activity of lin-14 extended life span. Lifespan extension conferred by a reduction in lin-14 was dependent ...


... using traditional automated DNA sequencers,” said Stellwag. “This capability will help us understand the complex genetic changes that are involved in species evolution, organism function, embryonic development and in genetic and infectious disease.” Scientists and faculty on both the East and West c ...
The Human Artificial Chromosome
The Human Artificial Chromosome

... beyond simply therapeutic treatments, its use may make it possible not only to prevent future disease, but also to provide benefits based on individuals’ choices. Ethicists will no doubt have a field day over the situation, but if HACs gain acceptance for germline use, humans begin to seize control of ...
DNA Arrays
DNA Arrays

... …as genes are linked to diseases, quick, inexpensive tests can be performed to determine who carries specific mutations, – gene must be mapped, cloned and sequenced, – DNA chips designed, and data storage and ...
Nitrogen Base Pairs
Nitrogen Base Pairs

... Different gene combinations, dominant and recessive Same gene pairs 9.What is a mutation? Are they always harmful? Permanent change to an organism No create variety ...
1) - life.illinois.edu
1) - life.illinois.edu

... 3). (20 Points). CTnDOT is a conjugative transposon originally found in Bacteroides. Work on the element produced the DNA sequence (attDOT) of the region involved in site-specific recombination of the element. The DNA sequence of the attDOT site is on the last page of the exam. (Just rip it off to u ...
PowerPoint Presentation - Creighton Chemistry Webserver
PowerPoint Presentation - Creighton Chemistry Webserver

... Promoter regions of studied genes contain active (dimethyl-H3K4) and repressive (trimethyl-H3K27) histone modifications in ES cells How detect methylated histone sites? Chromatin immunoprecipitation (ChIP) using antibodies to di- and tri- methylated histones; use beads to isolate ...
Scientific abstract
Scientific abstract

RAFT: Genetics - Catawba County Schools
RAFT: Genetics - Catawba County Schools

... Overview: These tiered RAFT assignments give students an opportunity to apply their knowledge of the key terms, concepts, and processes typically highlighted in a middle school-level genetics unit. They are listed in order of difficulty, with the first being the most difficult. Students may complete ...
MAPPFinder Powerpoint
MAPPFinder Powerpoint

... pathways as well as how they are regulated ...
Review - Jeopardy PowerPoint
Review - Jeopardy PowerPoint

... Color blindness is an example of a characteristic that results totally from __________ and is not ...
Quantitative PCR
Quantitative PCR

... • Forward and reverse primers (oligos) for each gene of interest • cDNA of control and treated samples (mock and infected, respectively) • SYBRGreen PCR mix ...
Carrier Screening for Recessive Diseases
Carrier Screening for Recessive Diseases

... Carriers like parents ...
Ways to get from plant genomes to phenomes: via
Ways to get from plant genomes to phenomes: via

... sense of the resulting overwhelming amount of sequence may require an equal effort. Several high-throughput tools for automated identification of genes at the structural level are available, but functional annotation can only be tentatively inferred on the basis of sequence motifs or sequence simila ...
Genetic Engineering Notes
Genetic Engineering Notes

... jellyfish cell and spliced (inserted) into an empty virus cell (with no bad virus in it) The genetically engineered virus attaches itself to the fertilized mouse egg cell. The virus delivers the glowing gene into the egg cell nucleus, where it joins the mouse DNA. The genetically engineered mouse eg ...
Biotech Overview
Biotech Overview

... Want to study or isolate a particular gene Need to get many copies (amplification) of the gene so it can be studied adequately Most organisms only have one or two copies of any gene per cell, so we need a way to amplify copies of that gene Do that via cloning into a vector This allows scientists to ...
< 1 ... 1176 1177 1178 1179 1180 1181 1182 1183 1184 ... 1288 >

Site-specific recombinase technology



Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report