anastrozole - Cancer Care Ontario
... megestrol recipients. However, more patients treated with megestrol acetate reported weight gain as an adverse event compared to patients treated with anastrozole. Anastrozole had statistically significant lower incidences of hot flashes, vaginal bleeding/discharge, endometrial cancer, venous t ...
... megestrol recipients. However, more patients treated with megestrol acetate reported weight gain as an adverse event compared to patients treated with anastrozole. Anastrozole had statistically significant lower incidences of hot flashes, vaginal bleeding/discharge, endometrial cancer, venous t ...
Slide 1
... Antipsychotic may cause acute dystonic reaction. As in (a), either antipsychotic or benzodiazepine may be used alone, but best results are likely with combination therapy. Ensure flumazenil injection is available to reverse effects of lorazepam injection. The maximum dose of olanzapine is 20mg/24 ho ...
... Antipsychotic may cause acute dystonic reaction. As in (a), either antipsychotic or benzodiazepine may be used alone, but best results are likely with combination therapy. Ensure flumazenil injection is available to reverse effects of lorazepam injection. The maximum dose of olanzapine is 20mg/24 ho ...
NAME OF THE MEDICINE: Desmopressin Acetate Synonyms
... with cardiopulmonary bypass for prosthetic valve replacement or aorto-coronary bypass grafting especially when it is complicated by platelet function defects sufficient to prolong bleeding time despite relatively normal platelet cover. DDAVP offers no benefit as routine therapy in patients having an ...
... with cardiopulmonary bypass for prosthetic valve replacement or aorto-coronary bypass grafting especially when it is complicated by platelet function defects sufficient to prolong bleeding time despite relatively normal platelet cover. DDAVP offers no benefit as routine therapy in patients having an ...
[Product Monograph Template
... The overall benefits and possible risks of hormone replacement therapy should be fully considered and discussed with patients. It is important that the modest increased risk of being diagnosed with breast cancer after 4 years of treatment with combined estrogen plus progestin HRT (as reported in the ...
... The overall benefits and possible risks of hormone replacement therapy should be fully considered and discussed with patients. It is important that the modest increased risk of being diagnosed with breast cancer after 4 years of treatment with combined estrogen plus progestin HRT (as reported in the ...
Nimesulide (PDF, 210KB, File is accessible)
... Gastrointestinal bleeding, ulceration and perforation: GI bleeding, ulceration or perforation, which can be fatal, has been reported with all NSAIDs at anytime during treatment, with or without warning symptoms or a previous history of GI events. The risk of GI bleeding, ulceration or perforation is ...
... Gastrointestinal bleeding, ulceration and perforation: GI bleeding, ulceration or perforation, which can be fatal, has been reported with all NSAIDs at anytime during treatment, with or without warning symptoms or a previous history of GI events. The risk of GI bleeding, ulceration or perforation is ...
GENERAL ANESTHETICS INHALATION ANESTHETICS
... Surmountable antagonists of the specific effects of narcotics (reduces potency of agonist) o Little effect when given alone, showing that endogenous opiates are not very active under normal circumstances ...
... Surmountable antagonists of the specific effects of narcotics (reduces potency of agonist) o Little effect when given alone, showing that endogenous opiates are not very active under normal circumstances ...
PACKAGE INSERT TEMPLATE FOR LACTULOSE Brand or Product
... Lactulose can be used during pregnancy. Lactation No effects on the breastfed newborn/infant are anticipated since the systemic exposure of lactulose to the breast-feeding woman is negligible. Lactulose oral solution can be used during breastfeeding Adverse Effects / Undesirable Effects Flatulance m ...
... Lactulose can be used during pregnancy. Lactation No effects on the breastfed newborn/infant are anticipated since the systemic exposure of lactulose to the breast-feeding woman is negligible. Lactulose oral solution can be used during breastfeeding Adverse Effects / Undesirable Effects Flatulance m ...
ROZEREM Tablet
... Ramelteon is absorbed rapidly, with median peak concentrations occuring at approximately 0.75 hour (range, 0.5 to 1.5 hours) after fasted oral administration. Although the total absorption of ramelteon is at least 84%, the absolute oral bioavailability is only 1.8% due to extensive first-pass metabo ...
... Ramelteon is absorbed rapidly, with median peak concentrations occuring at approximately 0.75 hour (range, 0.5 to 1.5 hours) after fasted oral administration. Although the total absorption of ramelteon is at least 84%, the absolute oral bioavailability is only 1.8% due to extensive first-pass metabo ...
5-Parkinson Disease
... The dose of amantadine in early PD is 200 to 300 mg daily; there is no evidence that larger doses are of additional benefit. The main advantage of this agent is a low incidence of side effects. • It is excreted unchanged in the urine and should be used with caution in the presence of renal failure. ...
... The dose of amantadine in early PD is 200 to 300 mg daily; there is no evidence that larger doses are of additional benefit. The main advantage of this agent is a low incidence of side effects. • It is excreted unchanged in the urine and should be used with caution in the presence of renal failure. ...
Lorabid Prescribing Information
... In subjects with moderate impairment of renal function (creatinine clearance 10 to 50 mL/min/1.73 m2), following a single 400-mg dose, the plasma half-life was prolonged to approximately 5.6 hours. In subjects with severe renal impairment (creatinine clearance <10 mL/min/1.73 m2), the half-life was ...
... In subjects with moderate impairment of renal function (creatinine clearance 10 to 50 mL/min/1.73 m2), following a single 400-mg dose, the plasma half-life was prolonged to approximately 5.6 hours. In subjects with severe renal impairment (creatinine clearance <10 mL/min/1.73 m2), the half-life was ...
Antibiotics - SeattleCloud
... Action: bactericidal. These drugs block the transpeptidase activity of penicillinbinding protein (PBP). Side effects: gastrointestinal alterations; non‐specific or C. difficile diarrhea, abdominal pain, nausea, vomiting. Thrombophlebitis, pain at the injection site. The major side e ...
... Action: bactericidal. These drugs block the transpeptidase activity of penicillinbinding protein (PBP). Side effects: gastrointestinal alterations; non‐specific or C. difficile diarrhea, abdominal pain, nausea, vomiting. Thrombophlebitis, pain at the injection site. The major side e ...
ARA Prescriber`s Information on Medications for Rheumatic
... Category C: Drugs which, owing to their pharmacological effects, have caused or may be suspected of causing, harmful effects on the human foetus or neonate without causing malformations. These effects may be reversible. Category D: Drugs which have caused, are suspected to have caused or may be expe ...
... Category C: Drugs which, owing to their pharmacological effects, have caused or may be suspected of causing, harmful effects on the human foetus or neonate without causing malformations. These effects may be reversible. Category D: Drugs which have caused, are suspected to have caused or may be expe ...
Hematologic problems in psychosomatic medicine psychatric
... The vaso-occulsive crisis is the hallmark of SCD → acute episodes of severe pain → extreme of temperature, infectious illness, → dehydration and physical exertion may → precipitate crises but, majority of crises → without an identifiable cause Vaso-occulsive produce: → acute pain → in short term → e ...
... The vaso-occulsive crisis is the hallmark of SCD → acute episodes of severe pain → extreme of temperature, infectious illness, → dehydration and physical exertion may → precipitate crises but, majority of crises → without an identifiable cause Vaso-occulsive produce: → acute pain → in short term → e ...
Prolixin/Prolixin Decanoate (fluphenazine)
... including schizophrenia, schizoaffective disorder, and drug-induced psychosis. The use of a drug for its approved indications is called its labeled use. In clinical practice, however, physicians often prescribe drugs for unlabeled (“off-label”) uses when published clinical studies, case reports, or ...
... including schizophrenia, schizoaffective disorder, and drug-induced psychosis. The use of a drug for its approved indications is called its labeled use. In clinical practice, however, physicians often prescribe drugs for unlabeled (“off-label”) uses when published clinical studies, case reports, or ...
Antiarrhythmic Drugs
... supraventriular arrhythmia, ventricular tachycardia, migraine prophylaxis. ...
... supraventriular arrhythmia, ventricular tachycardia, migraine prophylaxis. ...
Drugs and sex differences: a review of drugs relating to anaesthesia.
... in the British Medical Journal65 was soon followed by ‘Women recover faster than men from anaesthesia’ in the Lancet.56 Over the years an awareness has developed that in pharmacological studies the results from women should be analysed separately from men. This has arisen not only from sex differenc ...
... in the British Medical Journal65 was soon followed by ‘Women recover faster than men from anaesthesia’ in the Lancet.56 Over the years an awareness has developed that in pharmacological studies the results from women should be analysed separately from men. This has arisen not only from sex differenc ...
Full Prescribing Information - Upsher
... There is a lack of substantial evidence that androgens are effective in fractures, surgery, convalescence, and functional uterine bleeding. Pharmacokinetics Testosterone given orally is metabolized by the gut, and 44 percent is cleared by the liver in the first pass. Oral doses as high as 400 mg per ...
... There is a lack of substantial evidence that androgens are effective in fractures, surgery, convalescence, and functional uterine bleeding. Pharmacokinetics Testosterone given orally is metabolized by the gut, and 44 percent is cleared by the liver in the first pass. Oral doses as high as 400 mg per ...
The Efficacy of Synthetic Steroids to Inhibit Hormonal
... FI5 – concentration of compound-treated group in which the transcriptional activity is five times the transcriptional activity of the case without the compound. ...
... FI5 – concentration of compound-treated group in which the transcriptional activity is five times the transcriptional activity of the case without the compound. ...
ANTI FUNGAL DRUGS
... formulations have been developed in which amphotericin B is packaged in a lipid-associated delivery system, to assume that they will less bind to mammalian cell. Lipid vehicle act as a reservoir, reducing binding to human cell. In this way it permits a larger doses, even five times more than colloid ...
... formulations have been developed in which amphotericin B is packaged in a lipid-associated delivery system, to assume that they will less bind to mammalian cell. Lipid vehicle act as a reservoir, reducing binding to human cell. In this way it permits a larger doses, even five times more than colloid ...
Adenosine Pharmacology
... Do not confuse this drug with adenosine phosphate, which is used as adjunctive therapy in the treatment of complications associated with varicose veins. Due to the rapid metabolism it is imperative to administer the dose rapidly over 2 to 3 seconds. If given at a slower rate a reflex tachycardia may ...
... Do not confuse this drug with adenosine phosphate, which is used as adjunctive therapy in the treatment of complications associated with varicose veins. Due to the rapid metabolism it is imperative to administer the dose rapidly over 2 to 3 seconds. If given at a slower rate a reflex tachycardia may ...
MINISTRY OF HEALTH OF THE REPUBLIC OF BELARUS
... may be required. If renal function is unstable, creatinine clearance-adjusted evaluation will be unreliable. For patients with impaired renal function due to shock, severe heart failure or oliguria; for obese patients or patients suffering hepatic diseases, edemas or ascites; for fragile patients wi ...
... may be required. If renal function is unstable, creatinine clearance-adjusted evaluation will be unreliable. For patients with impaired renal function due to shock, severe heart failure or oliguria; for obese patients or patients suffering hepatic diseases, edemas or ascites; for fragile patients wi ...
Acetylcholinesterase Inhibitors for the Treatment of Mild to Moderate
... 4.6mg/24hours. Patches should be applied to sites on the upper or lower back, upper arm or chest but not to the abdomen or thigh areas due to decreased bioavailability of rivastigmine when the transdermal patch is applied to these areas of the body. The patch should be removed after 24 hours, and th ...
... 4.6mg/24hours. Patches should be applied to sites on the upper or lower back, upper arm or chest but not to the abdomen or thigh areas due to decreased bioavailability of rivastigmine when the transdermal patch is applied to these areas of the body. The patch should be removed after 24 hours, and th ...
Anabolic Steroids
... Testosterone Produced by Leydig’s cells in testes Responsible for secondary sex characteristics in men Sex glands, libido, reduced body fat percentage, increased body hair are all results from elevated levels ...
... Testosterone Produced by Leydig’s cells in testes Responsible for secondary sex characteristics in men Sex glands, libido, reduced body fat percentage, increased body hair are all results from elevated levels ...
Pharmaceutical Care III Fall 2007
... provider; over-use or incorrect use can be dangerous. Notify your doctor if any of the following occur: ...
... provider; over-use or incorrect use can be dangerous. Notify your doctor if any of the following occur: ...
Dydrogesterone
Dydrogesterone (INN, USAN, BAN), is also chemically known as 9β,10α-pregna-4,6-diene-3,20-dione. Dydrogesterone (6-dehydro-retroprogesterone) is a hormonally active, non-androgenic steroid that was developed in the 1950s.Dydrogesterone has selective progestational activity and does not inhibit ovulation. The greater rigidity of dydrogesterone also positively affects its selectivity, while natural progesterone is less selective, existing in different conformations that more easily bind to different receptors. As a consequence of its better bioavailability and the progestational activity of its main metabolites (20-, 21- and 16-hydroxy derivatives), the equivalent dose of dydrogesterone is 10–20 times lower than that of oral micronized progesterone.Dydrogesterone is used as an effective, orally active progestogen for gynaecological conditions related to a wide variety of progesterone deficiencies in pregnant women. The molecular structure and pharmacological effects are somewhat similar to endogenous progesterone, although in smaller amounts it is found to be orally active. Its freedom from hormonal effects like those related to corticoid, androgenic, estrogenic, anabolic, and other effects gives dydrogesterone an advantage over other synthesized progestogens.Dydrogesterone when used therapeutically is closely related to its physiological action on the neuro-endocrine control of ovarian function, as well as on the endometrium. This is an indication in all cases of endogeneous progesterone deficiency - relative or absolute. The molecule was licensed for use in several indications, including threatened or recurrent miscarriage, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhoea, irregular cycles, pre-menstrual syndrome and also as a hormone replacement therapy.Dydrogesterone has proven effective in the following conditions associated with progesterone deficiency: Infertility due to luteal insufficiency Threatened miscarriage Habitual or recurrent miscarriage. Menstrual disorders Premenstrual syndrome Endometriosis Dydrogesterone has also been registered as hormone replacement therapy (HRT) to counter-check the negative effects of unopposed estrogen on the endometrium in women with an intact uterus. Dydrogesterone is relatively safe and well tolerated, and does not exhibit the androgenic side effects that are common with some other progestins, like medroxyprogesterone acetate.