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Revised: November 2014 AN. 00340/2014 SUMMARY OF
Revised: November 2014 AN. 00340/2014 SUMMARY OF

... should be considered if signs develop. It is recommended that the animal should be monitored for signs of blood loss and treated appropriately Bleeding disorders such as nasal bleeding, haemorrhagic diarrhoea and haematomas have been reported. Local reactions such as a transient swelling have been o ...
Clopixol-Acuphase® 50 mg/ml Zuclopenthixol acetate
Clopixol-Acuphase® 50 mg/ml Zuclopenthixol acetate

... A single injection of zuclopenthixol acetate ensures a pronounced and rapid reduction of psychotic symptoms. The duration of action is 2 to 3 days and normally only one or two injections are sufficient before the patients can be switched to oral or depot treatment. Besides causing a significant redu ...
I can’t sleep, my pee smells funny, my bones hurt AND I’m
I can’t sleep, my pee smells funny, my bones hurt AND I’m

...  Long half-life may cause daytime sedation caution: driving  Anecdotally: ≤ 15mg may be more sedating than higher doses because of increased affinity for anticholinergic receptors at the lower dose ...
Physician Views: What Opportunity for Gilead Sciences' Hepatitis C Therapy
Physician Views: What Opportunity for Gilead Sciences' Hepatitis C Therapy

... backbone therapy for oral, interferon-free treatment regimens that emerge from 2015 onwards (including Gilead's proposed once-daily, one-tablet combination of sofosbuvir and ledipasvir). But what of its commercial opportunity in the meantime, assuming the drug is launched in early 2014? Sofosbuvir - ...
160-65-27 Eloctate Antihemophilic Factor Recombinant BDD FC
160-65-27 Eloctate Antihemophilic Factor Recombinant BDD FC

...  An independent 2 person check is required for all doses. Nurses from the Manitoba Bleeding Disorder Program are exempt from the independent 2 person check.  A nurse may administer a dose that provides: o Up to 200 international units greater than the prescribed dose; or o No more than 100 interna ...
Bacteriostatic Inhibitors of Protein Synthesis
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PIO Nas - Badan Pengawas Obat dan Makanan

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Rectodelt 100 mg suppositories - Biotech

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BETHANECHOL CHLORIDE TABLETS, USP 5 mg - Upsher

... stimulation are usually absent or minimal when orally or subcutaneously administered in therapeutic doses, while muscarinic effects are prominent. Muscarinic effects usually occur within 5 to 15 minutes after subcutaneous injection, reach a maximum in 15 to 30 minutes, and disappear within two hours ...
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N EW ETTER Asomex® by Emcure

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Baytril® 100 - Hagyard Pharmacy

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The following table summarizes mean percent changes from
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... with an intact uterus for the: 1.Treatment of moderate to severe vasomotor symptoms associated with the menopause. There is no adequate evidence that estrogens are effective for nervous symptoms or depression which might occur during menopause and they should not be used to treat these conditions. 2 ...
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... divided into three doses How many mg per dose? How much is the 24 hr drug total? 3. Give 30mg/kg administer orally in three divided doses How many mg per dose? How much is the 24 hr drug total? ...
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Nonsteroidal Antiinflammatory Drugs (NSAIDs)

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Plaquenil 200mg Film-coated Tablets

... The minimum effective dose should be employed and should not exceed 6.5mg/kg/day based on ideal body weight. The 200mg tablet is therefore not suitable for use in children with an ideal body weight of less than 31kg. Each dose should be taken with a meal or glass of milk. Hydroxychloroquine is cumul ...
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Oral Lichen Planus

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A Highly Efficacious Risedronate

... provided the same efficacy and safety as the daily 5 mg regimen; therefore, the lower dose, 35 mg OaW can be considered as optimal dose for PMOs or other osteoporotic patients who desire OaW regimen. In addition, RIS can be prescribed without dosage adjustment for patients with mild or moderate rena ...
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Dydrogesterone



Dydrogesterone (INN, USAN, BAN), is also chemically known as 9β,10α-pregna-4,6-diene-3,20-dione. Dydrogesterone (6-dehydro-retroprogesterone) is a hormonally active, non-androgenic steroid that was developed in the 1950s.Dydrogesterone has selective progestational activity and does not inhibit ovulation. The greater rigidity of dydrogesterone also positively affects its selectivity, while natural progesterone is less selective, existing in different conformations that more easily bind to different receptors. As a consequence of its better bioavailability and the progestational activity of its main metabolites (20-, 21- and 16-hydroxy derivatives), the equivalent dose of dydrogesterone is 10–20 times lower than that of oral micronized progesterone.Dydrogesterone is used as an effective, orally active progestogen for gynaecological conditions related to a wide variety of progesterone deficiencies in pregnant women. The molecular structure and pharmacological effects are somewhat similar to endogenous progesterone, although in smaller amounts it is found to be orally active. Its freedom from hormonal effects like those related to corticoid, androgenic, estrogenic, anabolic, and other effects gives dydrogesterone an advantage over other synthesized progestogens.Dydrogesterone when used therapeutically is closely related to its physiological action on the neuro-endocrine control of ovarian function, as well as on the endometrium. This is an indication in all cases of endogeneous progesterone deficiency - relative or absolute. The molecule was licensed for use in several indications, including threatened or recurrent miscarriage, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhoea, irregular cycles, pre-menstrual syndrome and also as a hormone replacement therapy.Dydrogesterone has proven effective in the following conditions associated with progesterone deficiency: Infertility due to luteal insufficiency Threatened miscarriage Habitual or recurrent miscarriage. Menstrual disorders Premenstrual syndrome Endometriosis Dydrogesterone has also been registered as hormone replacement therapy (HRT) to counter-check the negative effects of unopposed estrogen on the endometrium in women with an intact uterus. Dydrogesterone is relatively safe and well tolerated, and does not exhibit the androgenic side effects that are common with some other progestins, like medroxyprogesterone acetate.
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