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CYAMEMAZINE
CYAMEMAZINE

... • Lower doses should be used and patient should be monitored closely • Generally, doses above 100 mg/day are not recommended • Elderly patients with dementia-related psychosis treated with antipsychotics are at an increased risk of death compared to placebo, and also have an increased risk of cerebr ...
Product Monograph - Novo Nordisk Canada
Product Monograph - Novo Nordisk Canada

... progestin, when combined with estrogen, is to prevent endometrial hyperplasia/carcinoma in women with intact uteri. The addition of progestin for at least 12 days per cycle in non-hysterectomised women reduces this risk. In the WHI study, endometrial cancer rates were low and were not increased by 5 ...
Vm - Veterinary Medicines Directorate
Vm - Veterinary Medicines Directorate

... bodyweight, equivalent to 1 ml per 45 kg. Treatment may be repeated once or twice if colic recurs. For the treatment of endotoxaemia or shock-associated with gastric torsion and with other conditions in which the circulation of blood to the gastro-intestinal tract is compromised: 0.25 mg/kg (= 1 ml ...
ANTIHELMINTHICS
ANTIHELMINTHICS

...  Readily absorbed.  Extensive 1st pass metabolism producing inactive hydroxylated metabolites.  Excreted in urine and bile.  80% plasma protein bound. Half life of 1-3 hours. ...
CESAMET
CESAMET

... mechlorethamine (HN2). Without pretreatment, BCNU at 10 to 20 mg/kg evoked vomiting with an incidence of 50 percent (11 of 22 trials) and an average latency of 145 minutes. In contrast, after pretreatment with nabilone, BCNU failed to cause vomiting in any of 14 trials. HN2 at 5 mg/kg proved to elic ...
Opioid Prescribing in “Naive” or “Tolerant” Patients
Opioid Prescribing in “Naive” or “Tolerant” Patients

... recurrence rates of 11.1% for enucleation alone and 5.6% for Carnoy’s solution. The difference was not statistically significant; however, this study was underpowered. One retrospective study showed that Carnoy’s solution prevented recurrences statistically better than when it is not used. Modified ...
Factrel®
Factrel®

... FACTREL (gonadorelin hydrochloride) is indicated for the treatment of ovarian follicular cysts in cattle. The treatment effect of FACTREL when used in cattle with ovarian follicular cysts is a reduction in the number of days to first estrus. ...
2nd T. 6th L. Updated - Home - KSU Faculty Member websites
2nd T. 6th L. Updated - Home - KSU Faculty Member websites

...  Ketorolac is a heterocyclic acetic acid derivative. It is a potent analgesic but only a moderately effective antiinflammatory drug  It has a rapid onset of action, extensive protein binding, and a short duration of action. Oral bioavailability is about 80%. Urinary excretion accounts for about 90 ...
Percorten Product Insert
Percorten Product Insert

... the drug although there were no clinical measurements assessed in this study. In conclusion, PERCORTEN-V was well tolerated, when administered at 2.2 mg/kg on three consecutive days in every 28-day period for six months. DOSAGE:1,2 In treating canine hypoadrenocorticism, PERCORTEN-V replaces the min ...
Systemic Pharmaceuticals
Systemic Pharmaceuticals

... 500 mg. Dose is 1000 mg ( 1 gram) per day so dose according to tablet ŽCan use safely when tetracycline family can not be used (children, etc.) ŽBacteriostatic and terrible stomach upset ŽDose not have the lipid / acid modulating properties of the tetracyclines ...
women in placebo [see Warnings and Precautions (5.1)].
women in placebo [see Warnings and Precautions (5.1)].

... 15- to 24-fold for 5 to 10 years or more. This risk has been shown to persist for at least 8 to 15 years after estrogen therapy is discontinued. Adding a progestin to postmenopausal estrogen therapy has been shown to reduce the risk of endometrial hyperplasia, which may be a precursor to endometrial ...
drugs acting on the respiratory system bronchial asthma
drugs acting on the respiratory system bronchial asthma

... • Decreases frequency of asthma exacerbation and severity of symptoms The corticosteroids commonly used are hydrocortisone, predinisolone, beclomethasone, triamcinolone and etc. The drugs can be taken by inhalation as aerosol, oral, or an IV administration. Because of severe adverse effects when giv ...
Summary of product characteristics Alvesco (Ciclesonide) CLINICAL
Summary of product characteristics Alvesco (Ciclesonide) CLINICAL

... There are no adequate and well-controlled studies with Alvesco® in pregnant women. However, serum concentrations of ciclesonide are generally very low following inhaled administration; thus, fetal exposure is expected to be negligible and the potential for reproductive toxicity low. The excretion of ...
Pain (Medications and their Prescription) 311 MDS Dr. Hesham Kh
Pain (Medications and their Prescription) 311 MDS Dr. Hesham Kh

... bowel function, thus constipation should be expected whenever opioids are administered. Although rare (incidence is less than 1%), the most worrisome adverse effect of opioids is clinically significant respiratory depression. However, this can be prevented when with close monitoring of patients ever ...
GERD template word AK 1013
GERD template word AK 1013

... After 2-4 weeks if no improvement consider twice daily PPI. If still no response- investigate with endoscopy or pH/motility studies. Continued treatment with PPI if effective for 6-12 weeks. Tailor dose when coming off to reduce rebound dyspepsia. Some patients need longterm low dose PPI. Other Tx T ...
Furosemide Edema, initial dose: 20-40 mg/dose IV or IM
Furosemide Edema, initial dose: 20-40 mg/dose IV or IM

... Continuous infusion: 20-40 mg bolus IV, followed by 1040 mg/hour. Double the rate every 2 hours, up to a maximum 80-160 mg/hour. Edema, initial dose: 0.5-1 mg IV or IM. Repeat in 2-3 hours if response is inadequate, up to a maximum of 10 mg/day. Edema, maintenance dose: give the effective dose (from ...
Table 2. Dosage regimens of injectable loop diuretics7
Table 2. Dosage regimens of injectable loop diuretics7

... Continuous infusion: 20-40 mg bolus IV, followed by 1040 mg/hour. Double the rate every 2 hours, up to a maximum 80-160 mg/hour. Edema, initial dose: 0.5-1 mg IV or IM. Repeat in 2-3 hours if response is inadequate, up to a maximum of 10 mg/day. Edema, maintenance dose: give the effective dose (from ...
Diagnostic and Therapeutic Pitfalls in Myasthenia Gravis
Diagnostic and Therapeutic Pitfalls in Myasthenia Gravis

... • Risk of malignancy for treatment duration < 10 yrs is small • Lymphoma risk increased 4-fold or 1 case/1000 patient years • AML/ myelodysplasia rare • Increased risk of skin cancer – Skin protection with UVA blockers ...
Side Effects
Side Effects

... Drug Interactions  Steroids increase the metabolism of barbiturates, phenytoin, rifampicin, salicylates, antihypertensive, anti diabetic and increase in their dosage during concomitant therapy is therefore essential. ...
trusopt - Vision Institute Of Canada
trusopt - Vision Institute Of Canada

... In patients who are hypersensitive to any component of this product.: Dorzolamide has not been studied in patients with severe renal impairment (CrCl <30 mL/min). Because dorzolamide and its metabolite are excreted predominantly by the kidney, the drug is not recommended in such patients. There is a ...
prescribing information premarin® intravenous
prescribing information premarin® intravenous

... (Conjugated Estrogens for Injection, C.S.D.) 25 mg CE/vial ...
Document
Document

... • H2RAs are well absorbed after oral dosing • peak serum concentrations occur within one to three hours. • Absorption is reduced 10 to 20 percent by concomitant antacid administration, but not by food. • All four drugs cross the blood-brain and placental barriers and are excreted in breast milk ...
click here to the doc
click here to the doc

... produce increased or decreased plasma concentrations, respectively. This interaction was tested in vitro with concurrent administration of erythromycin, a known CYP 3A4 isozyme inhibitor, which resulted in increased plasma concentrations of Atosta. Atosta is also an inhibitor of cytochrome 3A4. It i ...
This abstract is not connected to an organized session. Biography
This abstract is not connected to an organized session. Biography

... CIT/esCIT decrease in the second half and specifically in the third trimester, presumably due to increased hepatic metabolism. However, the impact of these changes on depressive symptom relapse, and, in response, dose escalation has not been elucidated. My team was awarded funding from the National ...
VetACE Bioavailability and Pharmacodynamic Effect
VetACE Bioavailability and Pharmacodynamic Effect

... treatment of hypertension associated with cardiac or renal disease. The results of this in vivo study showed that administration of VetACE produced equal or greater suppression of serum Angiotensin Converting Enzyme activity at the expected time of peak effect compared to the pioneer product, Fortek ...
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Dydrogesterone



Dydrogesterone (INN, USAN, BAN), is also chemically known as 9β,10α-pregna-4,6-diene-3,20-dione. Dydrogesterone (6-dehydro-retroprogesterone) is a hormonally active, non-androgenic steroid that was developed in the 1950s.Dydrogesterone has selective progestational activity and does not inhibit ovulation. The greater rigidity of dydrogesterone also positively affects its selectivity, while natural progesterone is less selective, existing in different conformations that more easily bind to different receptors. As a consequence of its better bioavailability and the progestational activity of its main metabolites (20-, 21- and 16-hydroxy derivatives), the equivalent dose of dydrogesterone is 10–20 times lower than that of oral micronized progesterone.Dydrogesterone is used as an effective, orally active progestogen for gynaecological conditions related to a wide variety of progesterone deficiencies in pregnant women. The molecular structure and pharmacological effects are somewhat similar to endogenous progesterone, although in smaller amounts it is found to be orally active. Its freedom from hormonal effects like those related to corticoid, androgenic, estrogenic, anabolic, and other effects gives dydrogesterone an advantage over other synthesized progestogens.Dydrogesterone when used therapeutically is closely related to its physiological action on the neuro-endocrine control of ovarian function, as well as on the endometrium. This is an indication in all cases of endogeneous progesterone deficiency - relative or absolute. The molecule was licensed for use in several indications, including threatened or recurrent miscarriage, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhoea, irregular cycles, pre-menstrual syndrome and also as a hormone replacement therapy.Dydrogesterone has proven effective in the following conditions associated with progesterone deficiency: Infertility due to luteal insufficiency Threatened miscarriage Habitual or recurrent miscarriage. Menstrual disorders Premenstrual syndrome Endometriosis Dydrogesterone has also been registered as hormone replacement therapy (HRT) to counter-check the negative effects of unopposed estrogen on the endometrium in women with an intact uterus. Dydrogesterone is relatively safe and well tolerated, and does not exhibit the androgenic side effects that are common with some other progestins, like medroxyprogesterone acetate.
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