Proof-of-principle rapid noninvasive prenatal diagnosis
... size (Supplemental Table 4). Therefore, we sought a larger haplotype sequence to aid fetal diagnosis by mapping a consensus N370S founder region surrounding the GBA gene. Fine mapping of the consensus AJ N370S founder haplotype region. To fine map the N370S founder region, we sequenced 7 unrelated h ...
... size (Supplemental Table 4). Therefore, we sought a larger haplotype sequence to aid fetal diagnosis by mapping a consensus N370S founder region surrounding the GBA gene. Fine mapping of the consensus AJ N370S founder haplotype region. To fine map the N370S founder region, we sequenced 7 unrelated h ...
Structural Variants in the Human Genome
... 10,000 base long RNA genome Converted to DNA and integrate into genome with help of RNA reverse transcriptase and integrase enzymes and long tandem repeats (LTRs) Transcribed into RNA and produce virus (HIV) ...
... 10,000 base long RNA genome Converted to DNA and integrate into genome with help of RNA reverse transcriptase and integrase enzymes and long tandem repeats (LTRs) Transcribed into RNA and produce virus (HIV) ...
PowerPoint-Präsentation - European Bioinformatics Institute
... • To contribute to the advancement of biology through basic investigator-driven research in bioinformatics ...
... • To contribute to the advancement of biology through basic investigator-driven research in bioinformatics ...
Domain-Specific Synonym Expansion and
... If the topic contains “TGF beta”, documents talking about “TGF beta 1” or “TGF beta 2” are probably relevant as well. For every gene descriptor in the database, a search key was added with the last part of the gene symbol removed so that “TGF beta 1” can be found when searching for “TGF beta”. Why “ ...
... If the topic contains “TGF beta”, documents talking about “TGF beta 1” or “TGF beta 2” are probably relevant as well. For every gene descriptor in the database, a search key was added with the last part of the gene symbol removed so that “TGF beta 1” can be found when searching for “TGF beta”. Why “ ...
Inference of homologous recombination in bacteria using whole
... Bacteria and archaea reproduce clonally, but horizontal exchange of genetic material is known to occur in some organisms. In the majority of events, the imported DNA replaces an homologous segment in the recipient genome. We introduce a mathematical model that describes both the recipient and the or ...
... Bacteria and archaea reproduce clonally, but horizontal exchange of genetic material is known to occur in some organisms. In the majority of events, the imported DNA replaces an homologous segment in the recipient genome. We introduce a mathematical model that describes both the recipient and the or ...
Profile of Edward M. De Robertis - Howard Hughes Medical Institute
... says. “These were very exciting times, for Gehring’s group had discovered a gene sequence conserved in several Drosophila genes, called ‘homeotic genes,’ which regulate anteroposterior cell differentiation. After one of these seminars, Walter and I had a brainstorm in his office and decided to search ...
... says. “These were very exciting times, for Gehring’s group had discovered a gene sequence conserved in several Drosophila genes, called ‘homeotic genes,’ which regulate anteroposterior cell differentiation. After one of these seminars, Walter and I had a brainstorm in his office and decided to search ...
Codon usage bias from tRNA`s point of view
... species. Surprisingly, despite the wide G+C variation of bacterial genomes these anticodons are the same in most genomes. This suggests an optimization of the translation machinery to use a small subset of optimal codons and anticodons in fast-growing bacteria and in highly expressed genes. As a res ...
... species. Surprisingly, despite the wide G+C variation of bacterial genomes these anticodons are the same in most genomes. This suggests an optimization of the translation machinery to use a small subset of optimal codons and anticodons in fast-growing bacteria and in highly expressed genes. As a res ...
Genes involved in asexual sporophyte development in Ceratopteris
... plants. This life cycle delegates the major events of sexual reproduction, meiosis and fertilization, to two distinct, multicellular bodies: the diploid sporophyte and the haploid gametophyte. Meiosis in the sporophytic generation produces spores, which are the first cells of the gametophyte generat ...
... plants. This life cycle delegates the major events of sexual reproduction, meiosis and fertilization, to two distinct, multicellular bodies: the diploid sporophyte and the haploid gametophyte. Meiosis in the sporophytic generation produces spores, which are the first cells of the gametophyte generat ...
Article interaction G x tabac - Hal-CEA
... were detected for asthma by the MIT but not by the PST. These latter results might indicate presence of linkage without G x ETS interaction in these two regions. However, linkage analyses of asthma in the same EGEA data, ignoring G x E interaction, did not show evidence for linkage to these regions. ...
... were detected for asthma by the MIT but not by the PST. These latter results might indicate presence of linkage without G x ETS interaction in these two regions. However, linkage analyses of asthma in the same EGEA data, ignoring G x E interaction, did not show evidence for linkage to these regions. ...
Treatment of apple trees with streptomycin and potential risk to
... Resistance to antimicrobial treatment for bacterial pathogens was first described in the 1940’s and since then, resistance has been observed for all known antimicrobials (Levy, 1998). Antimicrobials have the undesirable effect of exerting selection pressure on otherwise rare resistant microorganism ...
... Resistance to antimicrobial treatment for bacterial pathogens was first described in the 1940’s and since then, resistance has been observed for all known antimicrobials (Levy, 1998). Antimicrobials have the undesirable effect of exerting selection pressure on otherwise rare resistant microorganism ...
Trans-acting siRNA-mediated repression of ETTIN
... near the C-terminal end of ARF4 (Fig. 1A). These mutations were chosen because their phenotype is slightly stronger than the suppressors isolated in our screens. The interaction between zip-2 and ett-7, ett-15 and arf4-2 was studied in F2 families generated by the self-pollination of plants heterozy ...
... near the C-terminal end of ARF4 (Fig. 1A). These mutations were chosen because their phenotype is slightly stronger than the suppressors isolated in our screens. The interaction between zip-2 and ett-7, ett-15 and arf4-2 was studied in F2 families generated by the self-pollination of plants heterozy ...
Molecular cloning and biochemical characterization of a
... several physiological events such as fruit ripening and senescence [3,4]. LOXs are also believed to play a role in lipid metabolism during seed germination [5,6]. LOXs are also of great interest in food science because hydroperoxides and free radicals resulting from LOX activity can have deleterious ...
... several physiological events such as fruit ripening and senescence [3,4]. LOXs are also believed to play a role in lipid metabolism during seed germination [5,6]. LOXs are also of great interest in food science because hydroperoxides and free radicals resulting from LOX activity can have deleterious ...
lecture17
... To separate linked QTL. If two QTL are close together on the same chromosome, our one-at-a-time strategy may have problems finding either (e.g. if they work in opposite directions, or interact). Our LOD scores won’t make sense either. ...
... To separate linked QTL. If two QTL are close together on the same chromosome, our one-at-a-time strategy may have problems finding either (e.g. if they work in opposite directions, or interact). Our LOD scores won’t make sense either. ...
Analyses of Mutants of Three Genes that Influence Root Hair
... Light and scanning electron microscopy -Mutant seedlings (rthllrthl, rth2lrth2, and rth3lrth3) were identified in segregating S, families via the root hair assay. Light microscopy was performed on fresh roots from 3-d-old seedlings in a Q60 genetic background (two to five backcrosses). For scanning ...
... Light and scanning electron microscopy -Mutant seedlings (rthllrthl, rth2lrth2, and rth3lrth3) were identified in segregating S, families via the root hair assay. Light microscopy was performed on fresh roots from 3-d-old seedlings in a Q60 genetic background (two to five backcrosses). For scanning ...
Supplementary Figures (doc 928K)
... entities). Stacked percentage distribution of level 0 cluster sizes from the group of all sequences, divided by cluster specificity. The “specificity” of a cluster is determined by the number of sequences that belong to the CLL group or the non-CLL group. If all sequences are non-CLL then the cluste ...
... entities). Stacked percentage distribution of level 0 cluster sizes from the group of all sequences, divided by cluster specificity. The “specificity” of a cluster is determined by the number of sequences that belong to the CLL group or the non-CLL group. If all sequences are non-CLL then the cluste ...
Chapter 8-Evolutionary Theory
... Inherited characteristics develop in most or all species members produced by natural selection because they solved an adaptive problem— functionality must have contributed to reproductive success, directly or indirectly need not be present at birth (teeth, breasts, beards, desires, emotions, persona ...
... Inherited characteristics develop in most or all species members produced by natural selection because they solved an adaptive problem— functionality must have contributed to reproductive success, directly or indirectly need not be present at birth (teeth, breasts, beards, desires, emotions, persona ...
A CRISPR-based yeast two-hybrid system for investigating
... since RNA polymerase III transcription can be terminated by even a relatively short poly(U) tract9, whereas RNA polymerase II termination signals are more complex and therefore should be rarer10,11. Thus, because premature termination of transcription in the middle of the hybrid sgRN ...
... since RNA polymerase III transcription can be terminated by even a relatively short poly(U) tract9, whereas RNA polymerase II termination signals are more complex and therefore should be rarer10,11. Thus, because premature termination of transcription in the middle of the hybrid sgRN ...
Adverse Effects of Excessive Leucine Intake Depend on Dietary
... protein levels. Male rats were divided into 12 groups (n56) and fed for 1 wk a diet containing low (6%), moderate (12%) or high (40%) protein. Different levels of Leu (0, 2, 4, and 8%) were added to the diets. Consumption of diets containing more than 4% Leu in 6% protein resulted in growth retardat ...
... protein levels. Male rats were divided into 12 groups (n56) and fed for 1 wk a diet containing low (6%), moderate (12%) or high (40%) protein. Different levels of Leu (0, 2, 4, and 8%) were added to the diets. Consumption of diets containing more than 4% Leu in 6% protein resulted in growth retardat ...
No Slide Title
... attacks never develop. Other treatments are designed to control an attack after it starts. ...
... attacks never develop. Other treatments are designed to control an attack after it starts. ...
A CRISPR-based yeast two-hybrid system for investigating
... since RNA polymerase III transcription can be terminated by even a relatively short poly(U) tract9, whereas RNA polymerase II termination signals are more complex and therefore should be rarer10,11. Thus, because premature termination of transcription in the middle of the hybrid sgRN ...
... since RNA polymerase III transcription can be terminated by even a relatively short poly(U) tract9, whereas RNA polymerase II termination signals are more complex and therefore should be rarer10,11. Thus, because premature termination of transcription in the middle of the hybrid sgRN ...
Sample Size Needed to Detect Gene-Gene Interactions
... family-based study design (9, 10) has received great attention in the last decade, both because of its robustness to population stratification and because of its power to identify genes with small-to-moderate effects (11). This design compares alleles transmitted to the affected children with those ...
... family-based study design (9, 10) has received great attention in the last decade, both because of its robustness to population stratification and because of its power to identify genes with small-to-moderate effects (11). This design compares alleles transmitted to the affected children with those ...
Unit 1 Review Answer Key 1. Define the following terms: a
... a. AABB: 100% of sperm would contain the alleles AB. b. AaBb: 25% of sperm would contain the alleles AB; 25% would contain the alleles Ab; 25% of sperm would contain the allele aB; 25% of sperm would contain the allele ab. c. aabb: 100% of sperm would contain the allele ab. d. AABb: 50% of sperm wou ...
... a. AABB: 100% of sperm would contain the alleles AB. b. AaBb: 25% of sperm would contain the alleles AB; 25% would contain the alleles Ab; 25% of sperm would contain the allele aB; 25% of sperm would contain the allele ab. c. aabb: 100% of sperm would contain the allele ab. d. AABb: 50% of sperm wou ...