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Pseudomonas are resistant to many antibiotics through low cell wall
Pseudomonas are resistant to many antibiotics through low cell wall

... Polymixin B, fusidic acid, florfenicol, gentamicin, enrofloxacin and marbofloxacin are suitable for most bacterial infections. Polymixin B and miconazole have synergistic activity against Pseudomonas and other Gram-negative organisms, and fusidic acid and framycetin show synergistic activity against ...
PEVISONE Janssen
PEVISONE Janssen

... Topical corticosteroids are associated with skin thinning and atrophy, striae, telangiectasis and purpura. Topical corticosteroids may lead to increased risk of dermatological superinfection or opportunistic infection. ...
Psychopharmacology Update
Psychopharmacology Update

... Suvorexant was safe and well tolerated for long term use ...
NOVEMBER 2016 PBAC MEETING – DEFERRALS DRUG
NOVEMBER 2016 PBAC MEETING – DEFERRALS DRUG

...  Approximately 15 additional patients would be expected to be alive at 18 months. There was a 3.2 month difference in median overall survival time favouring patients treated with nivolumab over those treated with docetaxel;  Approximately 17 fewer patients would experience a drug-related Grade 3 o ...
Saw Palmetto Botany
Saw Palmetto Botany

... • Eczema -- 320 mg to 8 G daily for adults and 1/2 that dose for children • Mastalgia -- 3 - 4 G daily ...
Clinical Discussion of Special Populations - M
Clinical Discussion of Special Populations - M

... When to conduct a pharmacokinetics (PK) study in pregnant women? • Per the 2004 Draft FDA Guidance1, PK studies in pregnant women are useful in the following situations: – Known to be prescribed or used by pregnant women, especially in 2nd or 3rd trimesters – For a new drug or indication, if there ...
Forms - Northeast Regional Epilepsy Group
Forms - Northeast Regional Epilepsy Group

... 200-300 mg twice a day and increase as tolerated; children is 15 mg per kilogram; frequent and regular blood work Specific Cautions Felbatol is recommended only for those patients whose epilepsy is so severe that a substantial risk of aplastic anemia or liver failure is considered acceptable in ligh ...
Saw Palmetto Botany
Saw Palmetto Botany

... • Eczema -- 320 mg to 8 G daily for adults and 1/2 that dose for children • Mastalgia -- 3 - 4 G daily ...
HIGHLIGHTS OF PRESCRIBING INFORMATION every other day) Decreased
HIGHLIGHTS OF PRESCRIBING INFORMATION every other day) Decreased

... administered daily to rabbits at a dose 0.5 times a human dose of 14 mcg or 0.24 mcg/kg (based on body surface area, mcg/m2), and when administered to rats at a dose two times the 0.24 mcg/kg human dose (based on body surface area, mcg/m2). At the highest dose tested, 20 mcg/kg administered three ti ...
LUPRON DEPOT® 7.5 mg (leuprolide acetate for depot suspension)
LUPRON DEPOT® 7.5 mg (leuprolide acetate for depot suspension)

... fetal harm when administered to a pregnant woman. Major fetal abnormalities were observed in rabbits but not in rats after administration of LUPRON DEPOT throughout gestation. There was increased fetal mortality and decreased fetal weights in rats and rabbits. The effects on fetal mortality are ...
Deep-HepRenSyn-Terlipressin - Pediatric Continuous Renal
Deep-HepRenSyn-Terlipressin - Pediatric Continuous Renal

... Previous studies CP score 11 Martin-Llahi M Gastroenterology 2008:134 ...
Product Monograph - Paladin Labs Inc.
Product Monograph - Paladin Labs Inc.

... Hepatic Function: Hepatotoxicity, a rare adverse reaction, has an estimated frequency of 0.10.2% in patients treated with propylthiouracil. Propylthiouracil-induced hepatotoxicity is not dose-related and is thought to be idiosyncratic with an autoimmune component. Hepatocellular necrosis and fulmina ...
Equivalent dose ratios for opioids Oral morphine
Equivalent dose ratios for opioids Oral morphine

... A rough guide is the dose of diamorphine (in mg over 24 hours) is in the region of the dose of fentanyl (in micrograms per hour) Injectable diamorphine : injectable alfentanil ...
Vol. 19, No. 2 To P.O. B12 or Not to P.O. B12 - medSask
Vol. 19, No. 2 To P.O. B12 or Not to P.O. B12 - medSask

... considered to be the threshold level for metabolic evidence of cobalamin deficiency. The researchers concluded that large daily oral doses of vitamin B12 were as effective as a standard parenteral regimen in producing hematologic and neurologic responses and possibly superior in increasing serum cob ...
Age
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... 65 yo and older Hx of noncardioembolic CVA Hx of GI Bleed > 1 Comorbid Conditions – Recent MI – Hct less than 30 – Creatinine > 1.5 – Diabetes Beyth et al. Am J Med 1998 ...
pdf
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... weighed against its benefits and then ...
ADHD in a College Population - American College Health Association
ADHD in a College Population - American College Health Association

... ✴ DA transporter blockade; NE transporter blockade ✴ d–isomer has greater pharmacologic activity than the l– isomer ‣ Majority of MPH products exist as 50/50 mixture • One exception: dexmethylphenidate (Focalin®) ...
Current Issues
Current Issues

... Fencino is the cheapest available Fentanyl patch on the market, all local hospitals are able and willing to hold stocks. There are no supply issues, the manufacturer guarantees that all the major wholesalers will have ample stock, and prices are guaranteed. Fencino patches are bio-equivalent to Duro ...
Xatabloc eye drops, solution ENG SmPC
Xatabloc eye drops, solution ENG SmPC

... Latanoprost may gradually change eye colour by increasing the amount of brown pigment in the iris. Similar to experience with latanoprost eye drops, increased iris pigmentation was seen in16-20% of all patients treated with latanoprost/timolol for up to one year (based on photographs). This effect h ...
Oral chemotherapy - American Nurse Today
Oral chemotherapy - American Nurse Today

... providers have dealt with nonadherent patients with chronic diseases, such as hypertension and asthma. In 2003, the World Health Organization recognized nonadherence as an issue of striking magnitude and predicted it would only get worse as chronic diseases increase in our aging population. Dr. C. E ...
Lidocaine Hydrochloride and Epinephrine
Lidocaine Hydrochloride and Epinephrine

... drug should not be exceeded. Injection should be made slowly and with frequent aspiration. Allow a 5minute interval between sides. Nursing Mothers: It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when lidocaine i ...
ROXICODONE - Mallinckrodt Pharmaceuticals
ROXICODONE - Mallinckrodt Pharmaceuticals

... to discontinue the use of non-opioid analgesic, it may be necessary to titrate the dose of ROXICODONE in response to the level of analgesia and adverse effects afforded by the dosing regimen. If the non-opioid regimen is continued as a separate single entity agent, the starting dose ROXICODONE shoul ...
Votrient - Novartis Pharmaceuticals Corporation
Votrient - Novartis Pharmaceuticals Corporation

...  Infection: Serious infections (with or without neutropenia), some with fatal outcome, have been reported. Monitor for signs and symptoms and treat active infection promptly. Interrupt or discontinue VOTRIENT. ...
keppra ® pi
keppra ® pi

... Antiepileptic drugs (AEDs), including KEPPRA, increase the risk of suicidal thoughts or behavior in patients taking these drugs for any indication. Patients treated with any AED for any indication should be monitored for the emergence or worsening of depression, suicidal thoughts or behavior, and/or ...
ZEMPLAR® (paricalcitol)
ZEMPLAR® (paricalcitol)

... the dose can be decreased to 1 mcg three times a week. If a further dose reduction is required, the drug should be withheld as needed and restarted at a lower dosing frequency. 2.2 Chronic Kidney Disease Stage 5 in Adults Initial Dose Administer the dose of ZEMPLAR capsules orally three times a week ...
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Ofloxacin



Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.
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