Pediatric Parenteral Nutrition
... Adverse effects – CNS and respiratory depressant Cardiac arrest with rapid injection Myoclonic jerking in premies ...
... Adverse effects – CNS and respiratory depressant Cardiac arrest with rapid injection Myoclonic jerking in premies ...
Abraxane - Celgene
... cells/mm3. In order to monitor the occurrence of bone marrow suppression, primarily neutropenia, which may be severe and result in infection, it is recommended that frequent peripheral blood cell counts be performed on all patients receiving ABRAXANE [see Contraindications (4), Warnings and Precauti ...
... cells/mm3. In order to monitor the occurrence of bone marrow suppression, primarily neutropenia, which may be severe and result in infection, it is recommended that frequent peripheral blood cell counts be performed on all patients receiving ABRAXANE [see Contraindications (4), Warnings and Precauti ...
FEC-D+TRAS Regimen - Cancer Care Ontario
... For trastuzumab, no adjustment required; the risk of cardiac dysfunction and myelosuppression may be increased in elderly patients. The reported trials did not determine differences in efficacy between patients > 65 years versus younger patients. ...
... For trastuzumab, no adjustment required; the risk of cardiac dysfunction and myelosuppression may be increased in elderly patients. The reported trials did not determine differences in efficacy between patients > 65 years versus younger patients. ...
Tubular Secretion active transport - University of California, Berkeley
... Excretion Toxicants are eliminated from the body by several routes: 1.Kidney is the most important route (urine) 2.Feces (biliary excretion) 3.Gases (lung) ...
... Excretion Toxicants are eliminated from the body by several routes: 1.Kidney is the most important route (urine) 2.Feces (biliary excretion) 3.Gases (lung) ...
PRODUCT INFORMATION XANAX alprazolam
... medication was measured, 71% - 93% of Xanax treated patients tapered completely off therapy compared to 89% - 96% of placebo treated patients. In a controlled clinical trial of 3 to 12 months duration involving 144 patients, where the ability of patients to discontinue medication was measured, it wa ...
... medication was measured, 71% - 93% of Xanax treated patients tapered completely off therapy compared to 89% - 96% of placebo treated patients. In a controlled clinical trial of 3 to 12 months duration involving 144 patients, where the ability of patients to discontinue medication was measured, it wa ...
Prolonged Seizures
... happened just before, the evolution of the episode, duration and what it looked like. Consider possibility of NAI, ask about fever and measures taken to control it, recent infection or vaccination, family history of epilepsy. Record current drug treatments, regular and emergency treatments already g ...
... happened just before, the evolution of the episode, duration and what it looked like. Consider possibility of NAI, ask about fever and measures taken to control it, recent infection or vaccination, family history of epilepsy. Record current drug treatments, regular and emergency treatments already g ...
Drug-induced acute pancreatitis
... possible causes and reporting the event. It can be difficult to rule out other causes of AP, especially in patients who have multiple comorbidities, use multiple medications, and have potentially unknown underlying risk factors. A retrospective study conducted in Germany concluded that the incidence ...
... possible causes and reporting the event. It can be difficult to rule out other causes of AP, especially in patients who have multiple comorbidities, use multiple medications, and have potentially unknown underlying risk factors. A retrospective study conducted in Germany concluded that the incidence ...
Beta-lactam antibiotics
... of the face, neck and trunk, a reaction which occurs during the infusion, and may be associated with hypotension. Nephrotoxicity and ototoxicity may occur in < 1% of pts especially those receiving other "toxic' drugs like aminoglycosides. A relationship between vancomycin level and nephrotoxicity or ...
... of the face, neck and trunk, a reaction which occurs during the infusion, and may be associated with hypotension. Nephrotoxicity and ototoxicity may occur in < 1% of pts especially those receiving other "toxic' drugs like aminoglycosides. A relationship between vancomycin level and nephrotoxicity or ...
Pharmacology: Relaxants and Local Anaesthetics
... documented in the literature relating to prilocaine in IVRA and we have conducted a survey within the U.K. which indicates that about 45,000 Bier's blocks have been carried out with prilocaine without convulsion, arrhythmia or fatality. This includes cases of accidental cuff deflation or even failu ...
... documented in the literature relating to prilocaine in IVRA and we have conducted a survey within the U.K. which indicates that about 45,000 Bier's blocks have been carried out with prilocaine without convulsion, arrhythmia or fatality. This includes cases of accidental cuff deflation or even failu ...
Antibiotic therapeutics in laboratory animals
... compounds and decrease the activity of bioactivated compounds metabolized through the same family of cytochromes required for the metabolism of many drugs (Burns & Conney 1965). Direct drug interactions may also occur, fluoroquinolones compete for gamma-amino butyric acid (CABA) receptor sites in th ...
... compounds and decrease the activity of bioactivated compounds metabolized through the same family of cytochromes required for the metabolism of many drugs (Burns & Conney 1965). Direct drug interactions may also occur, fluoroquinolones compete for gamma-amino butyric acid (CABA) receptor sites in th ...
Oral Disease-Modifying Therapies for Multiple Sclerosis
... The efficacy of fingolimod in patients with relapsing-remitting MS (RRMS) was first documented in a 6-month, double-blind, phase II core study and a 6-month extension study, during which both investigators and patients were unaware of the treatment assignments.13 The median total numbers of gadolini ...
... The efficacy of fingolimod in patients with relapsing-remitting MS (RRMS) was first documented in a 6-month, double-blind, phase II core study and a 6-month extension study, during which both investigators and patients were unaware of the treatment assignments.13 The median total numbers of gadolini ...
Il corretto uso dei diuretici nello scompenso cardiaco
... and pharmacodynamic principles. • Sequential nephron blockade with at least a loop diuretic and a thiazide, plus an antialdosteronic agent except in pts with severe renal dysfunction, is mandatory to achieve negative fluid and sodium balance. • Acetazolamide may be useful to circumvent excess proxim ...
... and pharmacodynamic principles. • Sequential nephron blockade with at least a loop diuretic and a thiazide, plus an antialdosteronic agent except in pts with severe renal dysfunction, is mandatory to achieve negative fluid and sodium balance. • Acetazolamide may be useful to circumvent excess proxim ...
Tasigna - Novartis Pharmaceuticals Corporation
... dose reduction should be considered and the QT interval should be monitored closely. (5.8) Total gastrectomy: More frequent follow-up of these patients should be considered. If necessary, dose increase may be considered. (5.13) Embryo-fetal toxicity: Fetal harm can occur when administered to a p ...
... dose reduction should be considered and the QT interval should be monitored closely. (5.8) Total gastrectomy: More frequent follow-up of these patients should be considered. If necessary, dose increase may be considered. (5.13) Embryo-fetal toxicity: Fetal harm can occur when administered to a p ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008.
... Nosten and White [5], had reported that if there is any toxicity observed in artemisinin combination treatments, it may be due to the non-artemisinin component as artemisinin derivatives alone may have relatively low toxicological effects. However, studies with animal had shown that artemisinin and ...
... Nosten and White [5], had reported that if there is any toxicity observed in artemisinin combination treatments, it may be due to the non-artemisinin component as artemisinin derivatives alone may have relatively low toxicological effects. However, studies with animal had shown that artemisinin and ...
the Presentation - Alabama Pharmacy Association
... A. Dabigatran 110mg dose proved superiority over warfarin in stroke reduction secondary to afib. B. Dabigatran can be used in patients on hemo‐ or peritoneal diaylsis C. Dabigatran is now approved post hip and knee replacement in the US D. Dabigatran can be started after the completion of 5‐10d ...
... A. Dabigatran 110mg dose proved superiority over warfarin in stroke reduction secondary to afib. B. Dabigatran can be used in patients on hemo‐ or peritoneal diaylsis C. Dabigatran is now approved post hip and knee replacement in the US D. Dabigatran can be started after the completion of 5‐10d ...
Opioid Dosing - San Francisco Health Plan
... Start with lower methadone doses for older patients, those with renal, liver or lung disease, or those on high doses of opiates. ...
... Start with lower methadone doses for older patients, those with renal, liver or lung disease, or those on high doses of opiates. ...
Clinical and experimental studies on theophylline
... • Steroids are the first line of drugs for asthma but are given along with bronchodilators like theophylline to reduce their dosage and reverse steroid resistance • Theophylline is an effective, pharmacoeconomically viable drug, but has a narrow therapeutic index, i.e. low margin of safety ...
... • Steroids are the first line of drugs for asthma but are given along with bronchodilators like theophylline to reduce their dosage and reverse steroid resistance • Theophylline is an effective, pharmacoeconomically viable drug, but has a narrow therapeutic index, i.e. low margin of safety ...
teratogenic risk for drugs
... lamotrigine during the first trimester and followed prospectively to birth were found to have congenital anomalies.[26] All of the mothers of children with malformations had a seizure disorder and some took at least one other medication during the pregnancy. Lamotrigine is an inhibitor of dihydrofol ...
... lamotrigine during the first trimester and followed prospectively to birth were found to have congenital anomalies.[26] All of the mothers of children with malformations had a seizure disorder and some took at least one other medication during the pregnancy. Lamotrigine is an inhibitor of dihydrofol ...
Saw Palmetto Botany
... • There is no evidence, either scientific or clinical, to support the use of pumpkin in the treatment of BPH. The potential benefit from the diuretic effects of the fatty acids is, at best, mild and minor. Better agents with known side effect and toxicity profiles provide better choices for the trea ...
... • There is no evidence, either scientific or clinical, to support the use of pumpkin in the treatment of BPH. The potential benefit from the diuretic effects of the fatty acids is, at best, mild and minor. Better agents with known side effect and toxicity profiles provide better choices for the trea ...
Product Information: Elvitegravir
... and the 50% effective concentration (EC50) values were in the range of 0.02 to 1.7 nM. Elvitegravir displayed antiviral activity in cell culture against HIV-1 clades A, B, C, D, E, F, G, and O (EC50 values ranged from 0.1 to 1.3 nM) and activity against HIV-2 (EC50 of 0.53 nM). The antiviral activit ...
... and the 50% effective concentration (EC50) values were in the range of 0.02 to 1.7 nM. Elvitegravir displayed antiviral activity in cell culture against HIV-1 clades A, B, C, D, E, F, G, and O (EC50 values ranged from 0.1 to 1.3 nM) and activity against HIV-2 (EC50 of 0.53 nM). The antiviral activit ...
What is the equivalent dose of oral prednisolone to intravenous (IV)
... The British National Formulary (BNF) includes a table on equivalent anti-inflammatory doses of glucocorticoids (2). It does not take account of mineralocorticoid effects nor does it take account of variations in the duration of action (2). From the literature, prednisolone 5mg is approximately equiv ...
... The British National Formulary (BNF) includes a table on equivalent anti-inflammatory doses of glucocorticoids (2). It does not take account of mineralocorticoid effects nor does it take account of variations in the duration of action (2). From the literature, prednisolone 5mg is approximately equiv ...
of administration (injection, oral or inhalation), BDP and its
... General: During withdrawal from oral corticosteroids, some patients may experience symptoms of systemically active corticosteroid withdrawal, e.g., joint and/or muscular pain, lassitude and depression, despite maintenance or even improvement of respiratory function. Although suppression of HPA funct ...
... General: During withdrawal from oral corticosteroids, some patients may experience symptoms of systemically active corticosteroid withdrawal, e.g., joint and/or muscular pain, lassitude and depression, despite maintenance or even improvement of respiratory function. Although suppression of HPA funct ...
Nintedanib in patients with idiopathic pulmonary fibrosis: Combined
... treatment of IPF in the US [8] and EU [9]. The efficacy and safety of nintedanib in patients with IPF have been investigated in three international Phase II/III trials with similar design. The TOMORROW trial (period 1) was a Phase II randomised, placebo-controlled, 52week, dose-finding trial of ninted ...
... treatment of IPF in the US [8] and EU [9]. The efficacy and safety of nintedanib in patients with IPF have been investigated in three international Phase II/III trials with similar design. The TOMORROW trial (period 1) was a Phase II randomised, placebo-controlled, 52week, dose-finding trial of ninted ...
Contraception in Renal Transplant Recipient
... NuvaRing® (Organon) is a silastic ring impregnated with etonorgestrel and ethinyl estradiol. It has the benefit of a once-a-month application, and may safely be used in either a 21- or 28-day cycle safely. As circulating levels of ethinyl estradiol are lower than those seen among COC users, and firs ...
... NuvaRing® (Organon) is a silastic ring impregnated with etonorgestrel and ethinyl estradiol. It has the benefit of a once-a-month application, and may safely be used in either a 21- or 28-day cycle safely. As circulating levels of ethinyl estradiol are lower than those seen among COC users, and firs ...
Autologous Serum Eye Drops
... – Used NPAT and ASE 20 % tid for 3 months in tapered fashion – Mean recurrence rate was reduced from 2.2 to 0.028/month of F/U (mean F/U 9.4 months) – Given self-healing nature of post-traumatic RES, the fact the duration since trauma was not specified, and the failure to state if other previously u ...
... – Used NPAT and ASE 20 % tid for 3 months in tapered fashion – Mean recurrence rate was reduced from 2.2 to 0.028/month of F/U (mean F/U 9.4 months) – Given self-healing nature of post-traumatic RES, the fact the duration since trauma was not specified, and the failure to state if other previously u ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.