Omalizumab in ABPA - Stanford University
... Interpatient variability to 100-fold (vs ~15-fold for itra) Pediatric doses 4 mg/kg vs 3 mg/kg in adults Usual maintenance dose 200 mg bid Suspension preferred to tablet TDM: target plasma steady-state trough 1-5.5 µg/mL Pasqualotto, Arch Dis Child 2008;93:578-81 ...
... Interpatient variability to 100-fold (vs ~15-fold for itra) Pediatric doses 4 mg/kg vs 3 mg/kg in adults Usual maintenance dose 200 mg bid Suspension preferred to tablet TDM: target plasma steady-state trough 1-5.5 µg/mL Pasqualotto, Arch Dis Child 2008;93:578-81 ...
Diclofenac versus Tramadol in the Treatment of Renal Colic: A
... Abstract: Objective: Nonsteroidal anti-inflammatory drugs are considered the mainstay in the treatment of renal colic. Nonsteroidal anti-inflammatory drugs are contraindicated in patients with renal failure and are not recommended in patients with certain diseases. In these cases other analgesics sh ...
... Abstract: Objective: Nonsteroidal anti-inflammatory drugs are considered the mainstay in the treatment of renal colic. Nonsteroidal anti-inflammatory drugs are contraindicated in patients with renal failure and are not recommended in patients with certain diseases. In these cases other analgesics sh ...
Corticosteroids in Asthma* Rationale, Use, and Problems
... of asthma in ambulatory As there is increasing emphasis on long-term use ...
... of asthma in ambulatory As there is increasing emphasis on long-term use ...
Eltor (pseudoephedrine hydrochloride)
... ELTOR 120 and an immediate-release pseudoephedrine animals being dosed once daily with ELTOR 120 and twice daily with the latter formulation. Initially, dose levels of 100 mg/kg/day were also used, but at this rate a death occurred in each treatment group within the first two days of treatment, and ...
... ELTOR 120 and an immediate-release pseudoephedrine animals being dosed once daily with ELTOR 120 and twice daily with the latter formulation. Initially, dose levels of 100 mg/kg/day were also used, but at this rate a death occurred in each treatment group within the first two days of treatment, and ...
antihypertensive drugs
... - fluid retention (usually combo-therapy with diuretic) - hypertrichosis (OTC, topical application as Rogaine) iii. Sodium Nitroprusside - used for acute emergency hypertension and congestive heart failure - used i.v., (cyanide toxicity via oral administration) - activation of guanylyl cyclase (dire ...
... - fluid retention (usually combo-therapy with diuretic) - hypertrichosis (OTC, topical application as Rogaine) iii. Sodium Nitroprusside - used for acute emergency hypertension and congestive heart failure - used i.v., (cyanide toxicity via oral administration) - activation of guanylyl cyclase (dire ...
Fosamax - Merck.com
... plain water only [see Patient Counseling Information (17.2)]. Other beverages (including mineral water), food, and some medications are likely to reduce the absorption of FOSAMAX [see Drug Interactions (7.1)]. Waiting less than 30 minutes, or taking FOSAMAX with food, beverages (other than plain wat ...
... plain water only [see Patient Counseling Information (17.2)]. Other beverages (including mineral water), food, and some medications are likely to reduce the absorption of FOSAMAX [see Drug Interactions (7.1)]. Waiting less than 30 minutes, or taking FOSAMAX with food, beverages (other than plain wat ...
ITEM 3: MCNEIL’S RESPONSE TO FDA’S PROPOSED LABELING... STEROIDAL ANTI-INFLAMMATORY DRUG (NSAID) PRODUCTS
... doctor’s care for any serious condition are directed to seek advice from their doctor or pharmacist before using an OTC NSAID. Thus, individuals with pre-existing liver disease, a serious condition, while not explicitly referenced in the proposed labeling, are implicitly directed to seek out health ...
... doctor’s care for any serious condition are directed to seek advice from their doctor or pharmacist before using an OTC NSAID. Thus, individuals with pre-existing liver disease, a serious condition, while not explicitly referenced in the proposed labeling, are implicitly directed to seek out health ...
MEMORANDUM Date: April 9, 2012 To: Vancomycin File From
... and staphylococcal enterocolitis. The usual adult total daily dosage is 500 mg to 2 g administered orally in 3 or 4 divided doses for 7 to 10 days. C. difficile-associated diarrhea: The recommended dose is 125 mg administered orally 4 times daily for 10 days.4 Staphylococcal enterocolitis: Total dai ...
... and staphylococcal enterocolitis. The usual adult total daily dosage is 500 mg to 2 g administered orally in 3 or 4 divided doses for 7 to 10 days. C. difficile-associated diarrhea: The recommended dose is 125 mg administered orally 4 times daily for 10 days.4 Staphylococcal enterocolitis: Total dai ...
Sample CMS-1450 (UB-04) Claim Form CMS-1450 (UB-04) Claim Form completion for VELCADE for
... route of administration has a different reconstituted concentration, caution should be used when calculating the volume to be administered. ▼ Peripheral neuropathy, including severe cases, may occur. Patients should be monitored for symptoms and peripheral neuropathy (including ≥Grade 3). Starting w ...
... route of administration has a different reconstituted concentration, caution should be used when calculating the volume to be administered. ▼ Peripheral neuropathy, including severe cases, may occur. Patients should be monitored for symptoms and peripheral neuropathy (including ≥Grade 3). Starting w ...
Paracetamol and codeine phosphate
... Coumarins: Paracetamol may increase the risk of bleeding in patients taking warfarin and other coumarin derivatives (antivitamin K). Monitoring of coagulation and bleeding complications is required. Chloramphenicol: Paracetamol may slow down the excretion of chloramphenicol, entailing the risk of i ...
... Coumarins: Paracetamol may increase the risk of bleeding in patients taking warfarin and other coumarin derivatives (antivitamin K). Monitoring of coagulation and bleeding complications is required. Chloramphenicol: Paracetamol may slow down the excretion of chloramphenicol, entailing the risk of i ...
Oral Dosing of Encochleated Amphotericin B (CAmB
... Conclusions: In Candida-infected mice, orally administered CAmB is taken up from the GI tract resulting in significant tissue concentrations above the MIC level. Contrary to DAmB, concentrations of AmB from CAmB accumulate rapidly in the tissues without escalating to extremely high levels during the ...
... Conclusions: In Candida-infected mice, orally administered CAmB is taken up from the GI tract resulting in significant tissue concentrations above the MIC level. Contrary to DAmB, concentrations of AmB from CAmB accumulate rapidly in the tissues without escalating to extremely high levels during the ...
Epilepsy
... been observed in many forms of primary generalized epilepsy. Patients with mental retardation, cerebral palsy, head injury, or strokes are at an increased risk for seizures and epilepsy In elderly, seizures are primarily of partial onset associated with the focal neuronal ...
... been observed in many forms of primary generalized epilepsy. Patients with mental retardation, cerebral palsy, head injury, or strokes are at an increased risk for seizures and epilepsy In elderly, seizures are primarily of partial onset associated with the focal neuronal ...
Monitoring for Hydroxychloroquine Retinal Toxicity
... by the literature; Wolfe and Marmor12 report a rate of 0.3% at 5 years. Therefore, I have a fairly low threshold for placing someone in the “higher risk” classification, thus requiring annual monitoring from the beginning. One point on which I diverge from the AAO screening guidelines is in dosage c ...
... by the literature; Wolfe and Marmor12 report a rate of 0.3% at 5 years. Therefore, I have a fairly low threshold for placing someone in the “higher risk” classification, thus requiring annual monitoring from the beginning. One point on which I diverge from the AAO screening guidelines is in dosage c ...
Nebulized or intravenous beta adrenoceptor agonist G.K.
... treatment However, unlike previous reports, nebulized therapy was associated with more subjective side-effects of tremor and palpitations than intravenous treatment. The nebulized route of administration was found to produce higher plasma levels of salbutamol at 55 and 90 min after the start of the ...
... treatment However, unlike previous reports, nebulized therapy was associated with more subjective side-effects of tremor and palpitations than intravenous treatment. The nebulized route of administration was found to produce higher plasma levels of salbutamol at 55 and 90 min after the start of the ...
Prescribing Information
... changes, increased appetite and weight gain. (6) Specific adverse reactions resulting from drug use in children under 2 years of age are increased risk of infections, hypertension, irritability, Cushingoid symptoms, cardiac hypertrophy and weight gain. (6.1.1) To report SUSPECTED ADVERSE REACTIONS ...
... changes, increased appetite and weight gain. (6) Specific adverse reactions resulting from drug use in children under 2 years of age are increased risk of infections, hypertension, irritability, Cushingoid symptoms, cardiac hypertrophy and weight gain. (6.1.1) To report SUSPECTED ADVERSE REACTIONS ...
1 - One Way
... Patient education and appropriate lifestyle advice regarding weight loss if obese, diet, and reduced alcohol (especially beer) are core aspects of management. ...
... Patient education and appropriate lifestyle advice regarding weight loss if obese, diet, and reduced alcohol (especially beer) are core aspects of management. ...
SUMMARY OF PRODUCT CHARACTERISTICS 1. NAME OF
... tachyarrhythmias, concomitant use of cardiac glycosides or diabetes mellitus. Patients should be instructed in the proper use of the inhaler and their technique checked, to ensure that the active substance reaches the target areas within the lungs. The management of asthma should normally follow a s ...
... tachyarrhythmias, concomitant use of cardiac glycosides or diabetes mellitus. Patients should be instructed in the proper use of the inhaler and their technique checked, to ensure that the active substance reaches the target areas within the lungs. The management of asthma should normally follow a s ...
Singulair - Merck.com
... SINGULAIR has been evaluated for safety in 476 pediatric patients 6 to 14 years of age. Cumulatively, 289 pediatric patients were treated with SINGULAIR for at least 6 months, and 241 for one year or longer in clinical trials. The safety profile of SINGULAIR in the 8-week, double-blind, pediatric ef ...
... SINGULAIR has been evaluated for safety in 476 pediatric patients 6 to 14 years of age. Cumulatively, 289 pediatric patients were treated with SINGULAIR for at least 6 months, and 241 for one year or longer in clinical trials. The safety profile of SINGULAIR in the 8-week, double-blind, pediatric ef ...
SPIRIVA® 18 microgram, inhalation powder, hard capsule
... Description of selected adverse reactions In controlled clinical studies, the commonly observed undesirable effects were anticholinergic undesirable effects such as dry mouth which occurred in approximately 4% of patients. In 28 clinical trials, dry mouth led to discontinuation in 18 of 9,647 tiotr ...
... Description of selected adverse reactions In controlled clinical studies, the commonly observed undesirable effects were anticholinergic undesirable effects such as dry mouth which occurred in approximately 4% of patients. In 28 clinical trials, dry mouth led to discontinuation in 18 of 9,647 tiotr ...
Systemic Antibiotics
... The higher molecular weight PBPs of Escherichia coli (PBP 1a and 1b) include the transpeptidases involved in the synthesis of peptidoglycan. Other PBPs maintain the rodlike shape, or are involved in the septum formation at division. The inhibition of some PBPs results in spheroplasts and rapid lysis ...
... The higher molecular weight PBPs of Escherichia coli (PBP 1a and 1b) include the transpeptidases involved in the synthesis of peptidoglycan. Other PBPs maintain the rodlike shape, or are involved in the septum formation at division. The inhibition of some PBPs results in spheroplasts and rapid lysis ...
FULL TEXT - OnCOReview
... necessary to investigate and define the best approach to the management of hypertensive emergencies in children. ...
... necessary to investigate and define the best approach to the management of hypertensive emergencies in children. ...
PRESCRIBING INFORMATION GARAMYCIN OPHTHALMIC
... related to gentamicin are ocular burning and irritation upon drug instillation, non-specific conjunctivitis, conjunctival epithelial defects and conjunctival hyperemia. Otic Use The possibility of ototoxicity following otic application should be kept in mind, and the patient monitored accordingly on ...
... related to gentamicin are ocular burning and irritation upon drug instillation, non-specific conjunctivitis, conjunctival epithelial defects and conjunctival hyperemia. Otic Use The possibility of ototoxicity following otic application should be kept in mind, and the patient monitored accordingly on ...
- I American Bic3Sciences
... summarized in Table Al. 1 in Appendix 1. In 3 studies the Avemar dose was 3000 mg/kg/day, equivalent to 210 g/day for a 70-pound human. In one study (Telekes et al. undated), a range of doses as high as 5000 mgikgday was used. The duration of administration of Avemar was from 15 days (Telekes et al. ...
... summarized in Table Al. 1 in Appendix 1. In 3 studies the Avemar dose was 3000 mg/kg/day, equivalent to 210 g/day for a 70-pound human. In one study (Telekes et al. undated), a range of doses as high as 5000 mgikgday was used. The duration of administration of Avemar was from 15 days (Telekes et al. ...
Product Monograph - Ask Novartis Pharma
... incidence of atrial fibrillation in isolated studies with some bisphosphonates, including AREDIA®, is unknown. Effects on ability to drive or use machines Somnolence and/or dizziness may occur following AREDIA® infusion, in which case the patient should not drive, operate potentially dangerous machi ...
... incidence of atrial fibrillation in isolated studies with some bisphosphonates, including AREDIA®, is unknown. Effects on ability to drive or use machines Somnolence and/or dizziness may occur following AREDIA® infusion, in which case the patient should not drive, operate potentially dangerous machi ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.