Testosterone Cypionate Injection, USP
... Geriatric patients treated with androgens may be at an increased risk of developing prostatic hypertrophy and prostatic carcinoma although conclusive evidence to support this concept is lacking. There have been postmarketing reports of venous thromboembolic events, including deep vein thrombosis (DV ...
... Geriatric patients treated with androgens may be at an increased risk of developing prostatic hypertrophy and prostatic carcinoma although conclusive evidence to support this concept is lacking. There have been postmarketing reports of venous thromboembolic events, including deep vein thrombosis (DV ...
Tetracycline group in children
... There are differences between different drugs in absorption, half life and bioavailability[1]. Absorption is greater in the fasting state and the percentage of an oral dose absorbed on an empty stomach is low for chlortetracyclines (30%); intermediate for oxytetracycline, demeclocycline, tetracyclin ...
... There are differences between different drugs in absorption, half life and bioavailability[1]. Absorption is greater in the fasting state and the percentage of an oral dose absorbed on an empty stomach is low for chlortetracyclines (30%); intermediate for oxytetracycline, demeclocycline, tetracyclin ...
Antidepressant medication table for Adults
... *This list includes a variety of drugs with side effects and act by different neurotransmitter mechanisms. The Lancet (1) concluded that sertraline offers the best balance among efficacy, acceptability, and costs compared to 11 other agents. Contraindications: Use of many antidepressants is contrain ...
... *This list includes a variety of drugs with side effects and act by different neurotransmitter mechanisms. The Lancet (1) concluded that sertraline offers the best balance among efficacy, acceptability, and costs compared to 11 other agents. Contraindications: Use of many antidepressants is contrain ...
Product Monograph
... bleeding events is not well understood. Based on the reports of major bleeding events from the ibrutinib global safety database of clinical trials and post-marketing exposure, a numerically increased risk of bleeding was observed in patients of older age (>65 years), patients with a history of blee ...
... bleeding events is not well understood. Based on the reports of major bleeding events from the ibrutinib global safety database of clinical trials and post-marketing exposure, a numerically increased risk of bleeding was observed in patients of older age (>65 years), patients with a history of blee ...
Lunesta
... Pharmacokinetic studies in elderly patients have revealed a tendency towards elevated blood concentration, suggesting that adverse reactions such as ataxia are likely to occur in such patients. Therefore, in elderly patients, LUNESTA should be administered at a single dose of 1 mg and the dose shoul ...
... Pharmacokinetic studies in elderly patients have revealed a tendency towards elevated blood concentration, suggesting that adverse reactions such as ataxia are likely to occur in such patients. Therefore, in elderly patients, LUNESTA should be administered at a single dose of 1 mg and the dose shoul ...
Suggestion from clinicians
... creatinine is greater than 30%, other causes of worsening renal function should first be excluded. In particular, assess volume status, as an increase in serum creatinine often appears in patients who are hypovolemic because of excessive diuresis. If no other cause for the worsening renal function c ...
... creatinine is greater than 30%, other causes of worsening renal function should first be excluded. In particular, assess volume status, as an increase in serum creatinine often appears in patients who are hypovolemic because of excessive diuresis. If no other cause for the worsening renal function c ...
Sex - jemds
... the patients. Only low osmolarity oral rehydration solution as advocated by WHO was given. No other antibiotic or antimotility drug was given during the course of study to either group. Oral rehydration solution was given after classifying the patients into with no dehydration, some dehydration or s ...
... the patients. Only low osmolarity oral rehydration solution as advocated by WHO was given. No other antibiotic or antimotility drug was given during the course of study to either group. Oral rehydration solution was given after classifying the patients into with no dehydration, some dehydration or s ...
NIZORAL 200 MG TABLETS
... decreased as deemed necessary. When appropriate, ketoconazole plasma concentrations should be measured. ...
... decreased as deemed necessary. When appropriate, ketoconazole plasma concentrations should be measured. ...
Anterior Segment Optical Coherence Tomography
... LUMIGAN ® (bimatoprost ophthalmic solution) 0.03% has been reported to cause changes to pigmented tissues. These reports include increased pigmentation and growth of eyelashes and increased pigmentation of the iris and periorbital tissue (eyelid).These changes may be permanent. LUMIGAN ® may gradual ...
... LUMIGAN ® (bimatoprost ophthalmic solution) 0.03% has been reported to cause changes to pigmented tissues. These reports include increased pigmentation and growth of eyelashes and increased pigmentation of the iris and periorbital tissue (eyelid).These changes may be permanent. LUMIGAN ® may gradual ...
HIGHLIGHTS OF PRESCRIBING INFORMATION
... Since the CYP3A4 isoenzyme plays a major role in the metabolism of oxycodone, drugs that alter CYP3A4 activity may cause changes in clearance of oxycodone which could lead to changes in oxycodone plasma concentrations. The expected clinical results with CYP3A4 inhibitors would be an increase in oxyc ...
... Since the CYP3A4 isoenzyme plays a major role in the metabolism of oxycodone, drugs that alter CYP3A4 activity may cause changes in clearance of oxycodone which could lead to changes in oxycodone plasma concentrations. The expected clinical results with CYP3A4 inhibitors would be an increase in oxyc ...
Pass Assured`s Pharmacy Technician Training Program
... What is the dose of Diazepam for Jill based on the mg/m2 , body surface area (BSA) dose given in the USP/DI? Body Surface Area (BSA) is based on Jill's weight and height and is read from a nomogram (nomograms for adults and children are included). Nomograms are used in the following way: Find the pa ...
... What is the dose of Diazepam for Jill based on the mg/m2 , body surface area (BSA) dose given in the USP/DI? Body Surface Area (BSA) is based on Jill's weight and height and is read from a nomogram (nomograms for adults and children are included). Nomograms are used in the following way: Find the pa ...
(oxycodone HCl, USP) Tablets for oral use
... Since the CYP3A4 isoenzyme plays a major role in the metabolism of oxycodone, drugs that alter CYP3A4 activity may cause changes in clearance of oxycodone which could lead to changes in oxycodone plasma concentrations. The expected clinical results with CYP3A4 inhibitors would be an increase in oxyc ...
... Since the CYP3A4 isoenzyme plays a major role in the metabolism of oxycodone, drugs that alter CYP3A4 activity may cause changes in clearance of oxycodone which could lead to changes in oxycodone plasma concentrations. The expected clinical results with CYP3A4 inhibitors would be an increase in oxyc ...
gemcitabine - Cancer Care Ontario
... avoid using as a prolonged infusion (more than 60 minutes) or more frequently than weekly since this can increase toxicity patients with impaired hepatic function, including concurrent liver metastases or a previous history of hepatitis, alcoholism or liver cirrhosis patients with renal impairment p ...
... avoid using as a prolonged infusion (more than 60 minutes) or more frequently than weekly since this can increase toxicity patients with impaired hepatic function, including concurrent liver metastases or a previous history of hepatitis, alcoholism or liver cirrhosis patients with renal impairment p ...
Cyclooxygenase inhibition: between the devil and the deep blue sea
... for more reports of drug related toxicity than any other class of drugs. Their most widely recognised adverse effects are on the gastrointestinal tract. They cause acute erosions and chronic ulcers that result in hospitalisation and death because of ulcer bleeding and perforation. Between them, aspi ...
... for more reports of drug related toxicity than any other class of drugs. Their most widely recognised adverse effects are on the gastrointestinal tract. They cause acute erosions and chronic ulcers that result in hospitalisation and death because of ulcer bleeding and perforation. Between them, aspi ...
What`s in the pipeline for 2014?
... If AFLURIA is administered to immunocompromised persons, including those receiving immunosuppressive therapy, the immune response may be diminished. AFLURIA should be given to a pregnant woman only if clearly needed. AFLURIA has not been evaluated in nursing mothers. It is not known whether AFLURIA ...
... If AFLURIA is administered to immunocompromised persons, including those receiving immunosuppressive therapy, the immune response may be diminished. AFLURIA should be given to a pregnant woman only if clearly needed. AFLURIA has not been evaluated in nursing mothers. It is not known whether AFLURIA ...
Clinical condition / indication(s) for use
... Any patients with a contra-indication should be reviewed by medical staff according to the severity of the condition. All patients with a generalised allergic reaction must be referred for further management. Side effects - A burning sensation in the nose and throat, local irritation, nausea, headac ...
... Any patients with a contra-indication should be reviewed by medical staff according to the severity of the condition. All patients with a generalised allergic reaction must be referred for further management. Side effects - A burning sensation in the nose and throat, local irritation, nausea, headac ...
Conjunctival Diseases
... chemosis and frequently pseudomembrane formation d)Prominent preauricular lymphadenopathy e)Keratitis may occur in severe cases ...
... chemosis and frequently pseudomembrane formation d)Prominent preauricular lymphadenopathy e)Keratitis may occur in severe cases ...
Potentially Harmful Drugs in the Elderly: Beers List
... is intended for use by clinicians in outpatient as well as inpatient settings (but not hospice or palliative care) to improve the care of patients 65 years of age and older.1 It includes medications that should be avoided, and medications that should be used with extra caution, either in all elderly ...
... is intended for use by clinicians in outpatient as well as inpatient settings (but not hospice or palliative care) to improve the care of patients 65 years of age and older.1 It includes medications that should be avoided, and medications that should be used with extra caution, either in all elderly ...
Oral hypoglycaemic drugs and newer agents use in Type 2 diabetes
... – 1.6% when using TZD as monotherapy in drug naïve patients. As combination therapy with sulphonylureas and metformin the reductions are synergistic and sustained. The A Diabetes Outcome Progression Trial (ADOPT), a large, international, multicentre trial evaluated the efficacy of rosiglitazone mono ...
... – 1.6% when using TZD as monotherapy in drug naïve patients. As combination therapy with sulphonylureas and metformin the reductions are synergistic and sustained. The A Diabetes Outcome Progression Trial (ADOPT), a large, international, multicentre trial evaluated the efficacy of rosiglitazone mono ...
Osteonecrosis of the Jaw — Do Bisphosphonates Pose a Risk?
... maxilla, or palate that typically heals poorly or does not heal over a period of 6 to 8 weeks. The diagnosis is primarily a clinical one, but imaging studies such as computed tomography can be helpful (see images). This condition in connection with bisphosphonate use was first reported in 2003, or 5 ...
... maxilla, or palate that typically heals poorly or does not heal over a period of 6 to 8 weeks. The diagnosis is primarily a clinical one, but imaging studies such as computed tomography can be helpful (see images). This condition in connection with bisphosphonate use was first reported in 2003, or 5 ...
Use and monitoring of Low Molecular Weight Heparins
... have this degree of renal impairment – dose may need to be reduced Hepatic failure (acute or chronic) – reduce dose or avoid in severe impairment Elderly Low body weight (increased risk of bleeding) ...
... have this degree of renal impairment – dose may need to be reduced Hepatic failure (acute or chronic) – reduce dose or avoid in severe impairment Elderly Low body weight (increased risk of bleeding) ...
1: gastro-intestinal system
... effects, and of central toxicity, i.e. restlessness, agitation, delirium. Children, the elderly, and patients with renal or hepatic impairment are more susceptible to the central effects of antimuscarinics. Various drugs not generally considered antimuscarinic have been shown to have detectable anti ...
... effects, and of central toxicity, i.e. restlessness, agitation, delirium. Children, the elderly, and patients with renal or hepatic impairment are more susceptible to the central effects of antimuscarinics. Various drugs not generally considered antimuscarinic have been shown to have detectable anti ...
Brimonidine P 0.1%
... were dosed thrice daily in this study as recommended in their prescribing information. It is unlikely that the additional afternoon dose of drugs affected the efficacy results, because all of the IOP measurements were taken prior to the second daily dose of medication given in the afternoon. Tra ...
... were dosed thrice daily in this study as recommended in their prescribing information. It is unlikely that the additional afternoon dose of drugs affected the efficacy results, because all of the IOP measurements were taken prior to the second daily dose of medication given in the afternoon. Tra ...
COTELLIC Product Monograph
... REACTIONS). Reductions in LVEF of Grade 2 or higher severity were reported in 7% of patients in the COTELLIC in combination with vemurafenib arm versus 3% of patients in the placebo in combination with vemurafenib arm. In the COTELLIC in combination with vemurafenib arm, median time to initial onset ...
... REACTIONS). Reductions in LVEF of Grade 2 or higher severity were reported in 7% of patients in the COTELLIC in combination with vemurafenib arm versus 3% of patients in the placebo in combination with vemurafenib arm. In the COTELLIC in combination with vemurafenib arm, median time to initial onset ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.