OXYTROL®
... Pregnancy Category B. There are no adequate and well-controlled studies using OXYTROL in pregnant women. OXYTROL should be used during pregnancy only if the potential benefit to the patient outweighs the risk to the patient and fetus. Women who become pregnant during OXYTROL treatment are encouraged ...
... Pregnancy Category B. There are no adequate and well-controlled studies using OXYTROL in pregnant women. OXYTROL should be used during pregnancy only if the potential benefit to the patient outweighs the risk to the patient and fetus. Women who become pregnant during OXYTROL treatment are encouraged ...
Side effects of glaucoma medications
... are commonly used in both eyes once or twice a day, and that patients often squeeze more than one drop upon instillation, the systemic implications can be dangerous (65). Subjects lacking of the cytochrome P 450 enzyme CYP2D6 allowing betablockers to be metabolized could have greater risk to develop ...
... are commonly used in both eyes once or twice a day, and that patients often squeeze more than one drop upon instillation, the systemic implications can be dangerous (65). Subjects lacking of the cytochrome P 450 enzyme CYP2D6 allowing betablockers to be metabolized could have greater risk to develop ...
Read full press release
... Corticosteroids (CS) have been the mainstay of uveitis approval of a variation treatment, but ocular and/or systemic adverse effects limit their long-term use in the treatment of intermediate, posterior, or panuveitis.15,16 There are few currently approved non-CS immunomodulatory agents for uveitis ...
... Corticosteroids (CS) have been the mainstay of uveitis approval of a variation treatment, but ocular and/or systemic adverse effects limit their long-term use in the treatment of intermediate, posterior, or panuveitis.15,16 There are few currently approved non-CS immunomodulatory agents for uveitis ...
SUMMARY OF PRODUCT CHARACTERISTICS
... have also been reported with high dose therapy. The incidence in elderly (>55 years) may be even higher. Other predisposing factors are impaired liver and renal function, previous CNS treatment (e.g., radiotherapy) and alcohol abuse. CNS disturbances are in the most cases reversible. The risk of CNS ...
... have also been reported with high dose therapy. The incidence in elderly (>55 years) may be even higher. Other predisposing factors are impaired liver and renal function, previous CNS treatment (e.g., radiotherapy) and alcohol abuse. CNS disturbances are in the most cases reversible. The risk of CNS ...
PIROXICAM PIROXICAM - The Filipino Doctor
... of pre-existing hypertension, either of which may contribute to the increased incidence of cardiovascular events. NSAIDs, including piroxicam (Feldene), should be used with caution in patients with hypertension. Blood pressure should be monitored closely during the initiation of therapy with piroxic ...
... of pre-existing hypertension, either of which may contribute to the increased incidence of cardiovascular events. NSAIDs, including piroxicam (Feldene), should be used with caution in patients with hypertension. Blood pressure should be monitored closely during the initiation of therapy with piroxic ...
COMMON PACE MEDICATIONS THAT REQUIRE RENAL DOSING
... Calculating Renal Clearance Renal Dosing for the Elderly Common PACE Medications That Require Renal Dosing ...
... Calculating Renal Clearance Renal Dosing for the Elderly Common PACE Medications That Require Renal Dosing ...
TARCEVA Product Monograph
... were symptomatic, and those with asymptomatic metastases but not on a stable dose of corticosteroids for at least 4 weeks prior to randomization. Therefore, the safety of TARCEVA in this patient population is unknown. In the EURTAC study, 20 patients in total with asymptomatic and stable CNS metasta ...
... were symptomatic, and those with asymptomatic metastases but not on a stable dose of corticosteroids for at least 4 weeks prior to randomization. Therefore, the safety of TARCEVA in this patient population is unknown. In the EURTAC study, 20 patients in total with asymptomatic and stable CNS metasta ...
SUMMARY OF PRODUCT CHARACTERISTICS 1 NAME OF THE
... Methylthioninium Chloride EmBlue may be administered orally or by intravenous (IV) injection. In the treatment of acute methaemoglobinaemia, the IV route of administration is usually preferred because it provides a more rapid onset of effect. However, in large doses, Methylthioninium Chloride can it ...
... Methylthioninium Chloride EmBlue may be administered orally or by intravenous (IV) injection. In the treatment of acute methaemoglobinaemia, the IV route of administration is usually preferred because it provides a more rapid onset of effect. However, in large doses, Methylthioninium Chloride can it ...
Lactulose and Ispaghula Husk Granules
... essentially complete within 24 hours. Ispaghula Husk is capable of absorbing up to 40 times its own weight of water in vitro, and part of its activity can be attributed to its action as a simple bulking agent. In addition, colonic bacteria are believed to use the hydrate material as a metabolic subs ...
... essentially complete within 24 hours. Ispaghula Husk is capable of absorbing up to 40 times its own weight of water in vitro, and part of its activity can be attributed to its action as a simple bulking agent. In addition, colonic bacteria are believed to use the hydrate material as a metabolic subs ...
Here - Vision Institute of Canada
... Brimonidine is available in three concentrations: the original 0.2%, which is the least expensive of the three; 0.15%, which is more expensive than the 0.2% formulation; and lastly, 0.1%. Both 0.2% and the 0.15% brimonidine are available generically. The 0.1% concentration is brand-name protected, a ...
... Brimonidine is available in three concentrations: the original 0.2%, which is the least expensive of the three; 0.15%, which is more expensive than the 0.2% formulation; and lastly, 0.1%. Both 0.2% and the 0.15% brimonidine are available generically. The 0.1% concentration is brand-name protected, a ...
Product Monograph
... duration of treatment a reliable predictor. Approximately 88% of the cases have occurred in the first twenty-six weeks of treatment, but some cases have developed after years of clozapine use. The incidence of neutropenia and agranulocytosis associated with the use of clozapine increases as a functi ...
... duration of treatment a reliable predictor. Approximately 88% of the cases have occurred in the first twenty-six weeks of treatment, but some cases have developed after years of clozapine use. The incidence of neutropenia and agranulocytosis associated with the use of clozapine increases as a functi ...
Update on the Management of Patients with Craniostenosis AAPOS 2011
... craniosynostosis can be complex. While recognizing that adequate care can be provided outside of craniofacial centers, due to the complex nature of the disorder we strongly believe that optimal care is best accomplished by teams of interdisciplinary specialists who are dedicated to the care and mana ...
... craniosynostosis can be complex. While recognizing that adequate care can be provided outside of craniofacial centers, due to the complex nature of the disorder we strongly believe that optimal care is best accomplished by teams of interdisciplinary specialists who are dedicated to the care and mana ...
full prescribing information for LATUDA
... Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Analyses of 17 placebo-controlled trials (modal duration of 10 weeks), largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of be ...
... Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Analyses of 17 placebo-controlled trials (modal duration of 10 weeks), largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of be ...
Zyban SPC (Mar 15)
... Although not metabolised by the CYP2D6 isoenzyme, bupropion and its main metabolite, hydroxybupropion, inhibit the CYP2D6 pathway. Co-administration of bupropion hydrochloride and desipramine to healthy volunteers known to be extensive metabolisers of the CYP2D6 isoenzyme resulted in large (2- to 5 ...
... Although not metabolised by the CYP2D6 isoenzyme, bupropion and its main metabolite, hydroxybupropion, inhibit the CYP2D6 pathway. Co-administration of bupropion hydrochloride and desipramine to healthy volunteers known to be extensive metabolisers of the CYP2D6 isoenzyme resulted in large (2- to 5 ...
Prescribing Information
... Varies with individual patient. Recommended adult starting dose is 60 mg once daily. Doses should be adjusted to individual patient needs and should continue for as long as clinically indicated. Dosages up to 90 mg twice daily have been administered. Daily dose of greater than 120 mg should be admin ...
... Varies with individual patient. Recommended adult starting dose is 60 mg once daily. Doses should be adjusted to individual patient needs and should continue for as long as clinically indicated. Dosages up to 90 mg twice daily have been administered. Daily dose of greater than 120 mg should be admin ...
A Rare Adverse Effect of Montelukast Treatment
... it affects nearly 300 million people, and there may be 100 million new patients by 2025.1 Allergic rhinitis is also a common disease; it affects 10 – 40% of the population in the United States.2,3 Evidence for the association between allergic rhinitis and asthma has been reported frequently in epide ...
... it affects nearly 300 million people, and there may be 100 million new patients by 2025.1 Allergic rhinitis is also a common disease; it affects 10 – 40% of the population in the United States.2,3 Evidence for the association between allergic rhinitis and asthma has been reported frequently in epide ...
for immediate release
... permanent. It has been reported mostly in patients who have been given excessive doses, who have an underlying hearing loss, or who are receiving concomitant therapy with another ototoxic agent, such as an aminoglycoside. • Patients with renal insufficiency should undergo serial monitoring of renal ...
... permanent. It has been reported mostly in patients who have been given excessive doses, who have an underlying hearing loss, or who are receiving concomitant therapy with another ototoxic agent, such as an aminoglycoside. • Patients with renal insufficiency should undergo serial monitoring of renal ...
aldactone
... Management of Cirrhosis: Although high doses of ALDACTONE are required to treat edema and ascites in patients with cirrhosis, the drug dosage may be decreased before diuresis is complete to avoid the possibility of dehydration. Neurologic: Lithium generally should not be given with diuretics (See D ...
... Management of Cirrhosis: Although high doses of ALDACTONE are required to treat edema and ascites in patients with cirrhosis, the drug dosage may be decreased before diuresis is complete to avoid the possibility of dehydration. Neurologic: Lithium generally should not be given with diuretics (See D ...
Amlodipin Bluefish tablet ENG SmPC
... arteries and coronary arterioles, both in normal and ischaemic regions. This dilatation increases myocardial oxygen delivery in patients with coronary artery spasm (Prinzmetal's or variant angina). In patients with hypertension, once daily dosing provides clinically significant reductions of blood p ...
... arteries and coronary arterioles, both in normal and ischaemic regions. This dilatation increases myocardial oxygen delivery in patients with coronary artery spasm (Prinzmetal's or variant angina). In patients with hypertension, once daily dosing provides clinically significant reductions of blood p ...
trastuzumab - Cancer Care Ontario
... Serious adverse effects associated with trastuzumab include infusion-related reactions (with acute respiratory distress syndrome) and cardiotoxicity. When given in combination with chemotherapy, the incidence of most adverse effects increases over those expected for either agent alone. Cardiotoxici ...
... Serious adverse effects associated with trastuzumab include infusion-related reactions (with acute respiratory distress syndrome) and cardiotoxicity. When given in combination with chemotherapy, the incidence of most adverse effects increases over those expected for either agent alone. Cardiotoxici ...
Cormax Cream PI.qxp
... Pregnancy: Teratogenic Effects: Pregnancy Category C: The more potent corticosteroids have been shown to be teratogenic in animals after dermal application. Clobetasol propionate has not been tested for teratogenicity by this route; however, it is absorbed percutaneously, and when administered subcu ...
... Pregnancy: Teratogenic Effects: Pregnancy Category C: The more potent corticosteroids have been shown to be teratogenic in animals after dermal application. Clobetasol propionate has not been tested for teratogenicity by this route; however, it is absorbed percutaneously, and when administered subcu ...
dabigatran - UHN Research
... Types of surgery associated with a high risk of bleeding (or in major surgery where complete hemostasis may be required) include, but are not limited to, cardiac surgery, neurosurgery, abdominal surgery, or those involving a major organ. Other procedures, such as spinal anesthesia, may also require ...
... Types of surgery associated with a high risk of bleeding (or in major surgery where complete hemostasis may be required) include, but are not limited to, cardiac surgery, neurosurgery, abdominal surgery, or those involving a major organ. Other procedures, such as spinal anesthesia, may also require ...
aricept - Pfizer
... predominant cholinesterase in the brain. Donepezil hydrochloride was found in vitro to be over 1000 times more potent an inhibitor of this enzyme than of butyrylcholinesterase, an enzyme which is present mainly outside the central nervous system. In patients with Alzheimer’s Dementia participating i ...
... predominant cholinesterase in the brain. Donepezil hydrochloride was found in vitro to be over 1000 times more potent an inhibitor of this enzyme than of butyrylcholinesterase, an enzyme which is present mainly outside the central nervous system. In patients with Alzheimer’s Dementia participating i ...
ENDOMETRIN (progesterone)
... Patients with a history of depression need to be closely observed. Consider discontinuation if symptoms worsen. 5.3 Use of Other Vaginal Products ENDOMETRIN should not be recommended for use with other vaginal products (such as antifungal products) as this may alter progesterone release and absorpti ...
... Patients with a history of depression need to be closely observed. Consider discontinuation if symptoms worsen. 5.3 Use of Other Vaginal Products ENDOMETRIN should not be recommended for use with other vaginal products (such as antifungal products) as this may alter progesterone release and absorpti ...
Here - Vision Institute of Canada
... Sometimes Older is Better “Antibiotic use should be appropriately limited, employing narrower spectrum or older agents whenever possible—particularly for mild or self-limiting infections. It should be recognized, further, that newer antimicrobials are not necessarily better than older ones: trimetho ...
... Sometimes Older is Better “Antibiotic use should be appropriately limited, employing narrower spectrum or older agents whenever possible—particularly for mild or self-limiting infections. It should be recognized, further, that newer antimicrobials are not necessarily better than older ones: trimetho ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.