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Here - Vision Institute of Canada
Here - Vision Institute of Canada

... Sometimes Older is Better “Antibiotic use should be appropriately limited, employing narrower spectrum or older agents whenever possible—particularly for mild or self-limiting infections. It should be recognized, further, that newer antimicrobials are not necessarily better than older ones: trimetho ...
Annex I : CSP – final clean version
Annex I : CSP – final clean version

... patients are taking Zyvox for longer than the recommended 28 days, their visual function should be regularly monitored. If peripheral optic neuropathy occurs, the continued use of Zyvox should be weighed against the potential risks. There may be an increased risk of neuropathies when linezolid is us ...
Paper Size: H 50 cm x W 48 cm
Paper Size: H 50 cm x W 48 cm

... In clinical studies, 13% of adult levetiracetam-treated patients and 38% of pediatric levetiracetam-treated patients (4 to 16 years of age) compared to 6% and 19% of adult and pediatric placebo-treated patients, experienced non-psychotic behavioral symptoms (reported as aggression, agitation, anger, ...
Full Prescribing Information
Full Prescribing Information

... ABSTRAL contains fentanyl, an opioid agonist and a Schedule II controlled substance, with an abuse liability similar to other opioid analgesics. ABSTRAL can be abused in a manner similar to other opioid agonists, legal or illicit. This should be considered when prescribing or dispensing ABSTRAL in s ...
Macrolids
Macrolids

... These unique properties permit once-daily dosing and shortening of the duration of treatment in many cases. For example, a single 1-g dose of azithromycin is as effective as a 7-day course of doxycycline for chlamydial cervicitis and urethritis. Community-acquired pneumonia can be treated with azith ...
Glucophage (metformin)
Glucophage (metformin)

... Safety in pregnant women has not been established. Metformin was not teratogenic in rats and rabbits at doses up to 600 mg/kg/day, or about two times the maximum recommended human daily dose on a body surface area basis. Determination of fetal concentrations demonstrated a partial placental barrier ...
zantac 150 zantac 300 zantac 25 zantac
zantac 150 zantac 300 zantac 25 zantac

... phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved on the tongue. Laboratory Tests: False-positive tests for urine protein with MULTISTIX® may occur during therapy with ZANTAC, and therefore testing with sulfosalicylic acid is ...
Hyoscyamine Sulfate Extended-Release Tablets, USP 0.375 mg
Hyoscyamine Sulfate Extended-Release Tablets, USP 0.375 mg

... Hyoscyamine sulfate is excreted in human milk. Caution should be exercised when hyoscyamine sulfate is administered to a nursing woman. Geriatric Use Reported clinical experience has not identified differences in safety between patients aged 65 and over and younger patients. In general, dose selecti ...
Fungal nail infection: Assessing the new treatment options W ■
Fungal nail infection: Assessing the new treatment options W ■

... heart failure, or in patients taking dofetilide, a class III antiarrhythmic medication. Itraconazole should be avoided during pregnancy. Adverse effects. Overall, itraconazole is well tolerated, with adverse effects reported in approximately 3% of patients.5 The more common adverse effects are: • He ...
ROXICET™ Oxycodone 5 mg and Acetaminophen 325 mg Tablets
ROXICET™ Oxycodone 5 mg and Acetaminophen 325 mg Tablets

... complication, especially after intra-abdominal surgery with use of opioid analgesia. Caution should be taken to monitor for decreased bowel motility in postoperative patients receiving opioids. Standard supportive therapy should be implemented. Use in Pancreatic/Biliary Tract Disease Oxycodone may c ...
Vancomycin dosing
Vancomycin dosing

... Stable therapeutic levels cannot be achieved Patient has severe renal impairment or is on dialysis Patient is not clinically improving 6. Additional Monitoring 6.1 Renal function There is some evidence that high dose vancomycin is associated with a greater risk of renal toxicity.6,8 For patients wit ...
FDA Takes Actions on Pain Medications Containing Propoxyphene
FDA Takes Actions on Pain Medications Containing Propoxyphene

... The agency is requiring manufacturers of propoxyphene-containing products to strengthen the label, including the Boxed Warning, emphasising the potential for overdose when using these products. These manufacturers will also be required to provide a Medication Guide to patients stressing the importan ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... mathirai(SSM) is the widely used Siddha herbo mineral formulation for the treatment of Pitha suram (Disorders of Liver associated with or without fever) . Currently there is no scientific data available for its safety profile and so the present study is to evaluate the toxicological potential if any ...
Practical Guidelines for Clinicians Who Treat Patients With
Practical Guidelines for Clinicians Who Treat Patients With

... during initial rapid infusion may improve significantly with a decrease in the rate of infusion.20-22 In contrast, supplemental IV boluses are frequently needed for patients with recurrent arrhythmias during the early phases of dosing. The recommended initial IV loading dose10,22 is 150 mg administ ...
Comparison  between  theophylline  and  an ... non-blocking  xanthine  in  acute  asthma
Comparison between theophylline and an ... non-blocking xanthine in acute asthma

... even when given in combination at high doses [11). Two multicentrc studies on the effects of xanthines in acute ast11ma have recently been completed. One demonstrated that even after large doses of salbutamol had been given e ither iv (0.2-0.5 mg) or by inhalation (7-15 mg) theophyiJine produced a h ...
HIGHLIGHTS OF PRESCRIBING INFORMATION
HIGHLIGHTS OF PRESCRIBING INFORMATION

... which may occur anytime after initiation, including after more than one year of treatment. Manifestations include dyspnea, fatigue, hypoxia, and fluid retention. PAH may be reversible on discontinuation of SPRYCEL. Evaluate patients for signs and symptoms of underlying cardiopulmonary disease prior ...
The Hospital for Sick Children Technology Assessment at SickKids (TASK)
The Hospital for Sick Children Technology Assessment at SickKids (TASK)

... Headache, fever, nausea, vomiting, and phlebitis at the site of infusion ...
Ken`s PowerPoint Slides
Ken`s PowerPoint Slides

... diuretic, calcium channel blocker, ACE inhibitor or ARB (Moderate) • Difference: JNC 7 recommended thiazides as first line treatment; beta blockers removed from first group of medications ...
2% XylocaineDENTAL with epinephrine 1:50000
2% XylocaineDENTAL with epinephrine 1:50000

... to women of childbearing potential, especially during early pregnancy when maximum organogenesis takes place. Nursing mothers It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when lidocaine is administered to a nu ...
Drugs used for Diabetes Mellitus
Drugs used for Diabetes Mellitus

... Recent guidelines recommend statin and low-dose aspirin treatment where the 10year coronary heart disease ridk is less than 15% -before adding aspirin ensure blood pressure is controlled -combination antihypertnsive treatment is necessary in the majority of patients to achieve blood pressure targets ...
Cordarone® Intravenous - Amiodarone-IV
Cordarone® Intravenous - Amiodarone-IV

... Apart from studies in patients with VT or VF, described below, there are two other studies of amiodarone showing an antiarrhythmic effect before significant levels of DEA could have accumulated. A placebo-controlled study of i.v. amiodarone (300 mg over 2 hours followed by 1200 mg/day) in postcorona ...
to our motrin information package
to our motrin information package

... thus inhibiting prostaglandin synthesis. As with other NSAIDs, ibuprofen inhibits platelet aggregation, but is not used therapeutically for this action since it is a minor and reversible effect. Adverse effects Ibuprofen appears to have the lowest incidence of gastrointestinal adverse drug reactions ...
Use of digoxin in older patients
Use of digoxin in older patients

... Thus, the aim of digitalis therapy is to improve quality of life, decreasing the symptoms and signs of heart failure and to prevent hospitalization. Heart failure is the most frequent cause of hospitalization among persons aged 65 years and above [2, 8]. Cardiac glycosides are widely used in older p ...
Talwin Nx (pentazocine and naloxone hydrochlorides)
Talwin Nx (pentazocine and naloxone hydrochlorides)

... antidepressants, and ethyl alcohol can enhance the central nervous system depressant effects of pentazocine (See WARNINGS). Tobacco smoking could enhance the metabolic clearance rate of pentazocine reducing the clinical effectiveness of a standard dose of pentazocine. Pentazocine can antagonize the ...
Attachment 1. Product Information for cobicistat
Attachment 1. Product Information for cobicistat

... patients receiving medications metabolized by CYP3A or initiating medications metabolized by CYP3A in patients already receiving TYBOST may result in increased plasma concentration of these concomitant medications. Higher plasma concentrations of concomitant medications can result in increased or pr ...
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Ofloxacin



Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.
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