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ASH Times - American Society of Hypertension
ASH Times - American Society of Hypertension

... When pregnancy is detected, discontinue AVAPRO or AVALIDE as soon as possible. When used in pregnancy during the second and third trimesters, drugs that act directly on the renin-angiotensin system can cause injury and even death to the developing fetus. [See Warnings and Precautions: Fetal/Neonatal ...
niaspan - Sunovion Pharmaceuticals Canada Inc.
niaspan - Sunovion Pharmaceuticals Canada Inc.

... in the simvastatin plus NIASPAN FCT group and 15 (0.9%) in the simvastatin plus placebo group, a non-statistically significant result (HR 1.79, [95%CI = 0.95-3.36], p=0.071). The ontreatment ischemic stroke events were 19 for the simvastatin plus NIASPAN FCT group and 15 for the simvastatin plus pla ...
Analgesia en pacientes con ERC
Analgesia en pacientes con ERC

... DOSING: ADULTS or ELDERLY Doses >1.5 mg/kg body weight are not recommended. Pain management (analgesic): Oral, regular release: 30 mg every 4-6 hours as needed; patients with prior opiate exposure may require higher initial doses. Usual range: 15-120 mg every 4-6 hours as needed Oral, controlled rel ...
t.5
t.5

... GIT absorption of orally administered TCA is almost complete but since the drug passes through the liver & suffers from first-pass metabolism (FPM); the (F) is decreased to 50% in most patients. For that (F) range is broad & difficult to estimate in any individual patient. Rate of absorption is v ...
Depakote - UnitedHealthcareOnline.com
Depakote - UnitedHealthcareOnline.com

... corresponding release product as evidenced by one of the following: i. Change in seizure frequency from baseline ii. Breakthrough seizures not explained by medication nonadherence or significant provoking factor iii. Status epilepticus -OR(b) Documented history of intolerance to the corresponding re ...
COTELLIC + ZELBORAF: Adverse drug reactions guide for
COTELLIC + ZELBORAF: Adverse drug reactions guide for

... COTELLIC + ZELBORAF. This guide provides information on the most serious and most common adverse drug reactions (ADRs) that may occur with COTELLIC + ZELBORAF treatment and how to • Monitor patients for symptoms of serious or common ADRs • Manage ADRs where appropriate guidance can be given. Plea ...
The Questions You Asked and the Answers You Need
The Questions You Asked and the Answers You Need

... than the daily human topical dose, 0.001 mg/kg/day, assuming that the entire dose is absorbed. No adverse events were observed at oral doses up to 15 mg/kg/day (15,000 times greater than the daily human dose). There are no adequate and well-controlled studies of RESTASIS® in pregnant women. RESTASIS ...
NSAIDs
NSAIDs

... The active ingredient of Willow bark , Salicin , which on hydrolysis yields salicylic acid , was later found in other natural sources. Acetyl salicylic acid was synthesized in 1853, but the drug was note used until 1899, when it is found to effective in arthritis. Because of its greater efficacy and ...
Click here
Click here

... Long duration of action breaks repeat dosing habit Less opiate side effects- nausea, constipation, sexual dysfunction Less neonatal abstinence syndrome Less severe withdrawal symptoms if stopped Increased patient satisfaction ...
BUPROPION HYDROCHLORIDE
BUPROPION HYDROCHLORIDE

... of treatment at 300 mg/day (Prod Info Wellbutrin(R) SR, 1999). 3. A maximum bupropion dose of 450 milligrams/day may be considered for patients who are unresponsive to several weeks of 300 milligrams/day (Prod Info Wellbutrin(R), 1999). Single doses of bupropion should not exceed 150 milligrams. The ...
New Jersey Department of Children and Families Psychotropic Medication Policy
New Jersey Department of Children and Families Psychotropic Medication Policy

... diagnosis, the strengths and needs that the child and family bring to the treatment process, and the resources of the community. A treatment plan should include appropriate behavior planning, monitoring of symptoms and medication effects, and on-going communication between the prescriber and the chi ...
Penicillins
Penicillins

... Penicillins are distributed widely to most areas of the body, including the lungs, liver, kidneys, muscle, bone, and placenta. High concentrations also appear in urine, making penicillins useful in treating UTIs. All the penicillins cross the placental barrier, but none has been shown to be teratoge ...
TETRACYCLINE AND DOXYCYCLINE APPLICATIONS
TETRACYCLINE AND DOXYCYCLINE APPLICATIONS

... infectious diseases. Although both are considered to be broad spectrum, many common pathogens have acquired resistance to them, leaving a fairlyfinite list of indicated uses. This list includes the treatment of several sexually transmitted diseases, pelvic inflammatory disease and endometritis, and ...
VALIUM brand of diazepam TABLETS Rx Only WARNING: RISKS
VALIUM brand of diazepam TABLETS Rx Only WARNING: RISKS

... orally at daily doses of 100 mg/kg or greater (approximately eight times the maximum recommended human dose [MRHD=1 mg/kg/day] or greater on a mg/m2 basis). Cleft palate and encephalopathy are the most common and consistently reported malformations produced in these species by administration of high ...
Fife Minor Ailments Service Formulary
Fife Minor Ailments Service Formulary

... >> Assist in making appropriate and cost-effective choices. The formulary provides pharmacists with a recommended list from which a variety of minor ailments can be treated. Most entries are listed by generic drug name due to the difference of branded preparation available in pharmacies. The medici ...
Essential Tremor Slide Set
Essential Tremor Slide Set

... • Potential ability to perform bilateral operations for hand tremor with reduced risk of morbidity • Late tremor recurrence addressed by adjustments of pulse generator programming parameters Pahwa Rajesh, Koller William C. Surgical treatment of essential tremor. ...
Product Monograph - AstraZeneca Canada
Product Monograph - AstraZeneca Canada

... In the case of acute or rapidly worsening dyspnea, a doctor should be consulted immediately. Increasing use of β2-agonists to control symptoms of bronchial obstruction, especially administration on a regular basis or in high amounts, indicates deterioration of asthma control. Under these conditions, ...
NWQA240_3_miconazole_gel_statins_interaction
NWQA240_3_miconazole_gel_statins_interaction

... There do not appear to be any reports of an interaction between miconazole and any of the statins. However, like fluconazole, miconazole is an inhibitor of CYP3A4 and CYP2C9, and might be expected to interact in a similar way [2,4]. Fluconazole Rhabdomyolysis in patients taking a statin and fluconaz ...
ANGIOTENSIN II RECEPTOR BLOCKERS: AN OVERVIEW  Review Article
ANGIOTENSIN II RECEPTOR BLOCKERS: AN OVERVIEW Review Article

... therapy, with maximum effects occurring at between two and six weeks.34-36 Effects on blood pressure are dose dependent over the range of 75-300 mg.37,38 However, data from various double-blind, placebo-controlled trials show that daily doses of 150-300 mg, administered once daily or in divided dose ...
Pharmacokinetics - Therapeutic Goods Administration
Pharmacokinetics - Therapeutic Goods Administration

... concentration (IC50) value for emtricitabine was in the range of 0.0013 to 0.64 µM. In drug combination studies of emtricitabine with nucleoside reverse transcriptase inhibitors (abacavir, lamivudine (3TC), stavudine (d4T), tenofovir, zalcitabine, zidovudine), nonnucleoside reverse transcriptase inh ...
Zonisamide (Zonegran®) Clinicians initiating this medication should
Zonisamide (Zonegran®) Clinicians initiating this medication should

... necessary, the patient should be closely monitored and the dose of zonisamide and other ...
Topamax SPC
Topamax SPC

... Hydrochlorothiazide (HCTZ): A drug-drug interaction study conducted in healthy volunteers evaluated the steady-state pharmacokinetics of HCTZ (25 mg q24h) and topiramate (96 mg q12h) when administered alone and concomitantly. The results of this study indicate that topiramate Cmax increased by 27% a ...
PDF - ECronicon
PDF - ECronicon

... Conclusion: Providing surgeons with reliable practice-based feedback can increase their confidence in offering premium lenses to patients. The study facilitates the refractive surgeon on patient selection for mini-monovision or multifocal intra-ocular lenses. ...
Non-vitamin K antagonist oral anticoagulants (NOACs): clinical
Non-vitamin K antagonist oral anticoagulants (NOACs): clinical

... denote ‘Non-vitamin K antagonist Oral AntiCoagulants’, when referring to these direct inhibitors of single coagulation factors.5 NOACs are effective alternatives to VKAs for the treatment and prevention of thromboembolic disease. These agents do not require monitoring or dose adjustment and thus rep ...
Therapeutic Interchange Policy (TIP)
Therapeutic Interchange Policy (TIP)

... pantoprazole 40 mg or 80 mg rabeprazole 20 mg or 40 mg * Exceptions: NG orders for Helicobacter pylori are exempt from this interchange and should be interchanged to esomeprazole 20 mg NG BID. ** Daily maximum esomeprazole dose for this interchange is 40 mg except for Zollinger-Ellison Syndrome Call ...
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Ofloxacin



Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.
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