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Powerpoint Slides - people.csail.mit.edu
Powerpoint Slides - people.csail.mit.edu

... • Chronic fatigue, muscle pain, joint pain, brain fog • Alum nanoparticles adsorb vaccine antigens on their surface -> resistance to proteolysis • Defects in autophagy  biopersistence of alum particles • Trojan horse effect: immune cells carry Al into brain • Leaky brain barrier Alum accumulates i ...
View PDF - OMICS International
View PDF - OMICS International

... generated may not be as high as those produced from live attenuated vaccines. J Bioterr Biodef ...
Autoimmune disease and infection
Autoimmune disease and infection

... predominate in adolescents or young adults, and thyroid autoimmune diseases generally affect elderly individuals What is meant by the term trigger? Some events do not cause autoimmunity but can lead to the exacerbation (triggering) of an underlying silent autoimmune process, and thus to the clinical ...
8 Prevention of Hepatitis A, B and C and Other
8 Prevention of Hepatitis A, B and C and Other

... • HCV mother-to-child transmission (MTCT) in HIV-infected women is high (between 5% and 20%) (10). When possible, HCV treatment should be offered before pregnancy to women of childbearing age. Although several MTCT risk factors have been identified, there are currently no interventions available to ...
Scand J Immunol 2000 Aug
Scand J Immunol 2000 Aug

Modeling the Effects of Prior Infection on Vaccine Efficacy
Modeling the Effects of Prior Infection on Vaccine Efficacy

... Prior infection sometimes decreased vaccine efficacy below the situation when there was vaccination without prior infection (groups 24, 29, and 34, on the upper diagonal of Figure 2d). This occurred because the prior infection was far enough from the epidemic strain to provide little protection, but ...
Atherosclerosis
Atherosclerosis

... reduces atherosclerosis (George et al : Atherosclerosis ...
Pertussis Awareness
Pertussis Awareness

... • Persons with pertussis are most infectious during the catarrhal period starting as early as one day of cough • Some individuals, such as infants who remain culture-positive for several weeks, may be infectious for a longer period ...
Immunogenic Consensus Sequence T Helper Epitopes for a Pan
Immunogenic Consensus Sequence T Helper Epitopes for a Pan

Induction of Neonatal Tolerance by Plasmid DNA Vaccination
Induction of Neonatal Tolerance by Plasmid DNA Vaccination

DNA Vaccines Non-Amplifiable in Eukaryotic cell for
DNA Vaccines Non-Amplifiable in Eukaryotic cell for

... The origin of the gene of interest should be described in detail, such as the name of the microorganism or cell from which the gene was derived, the origin of the source, its species, passage history, subtype and isolation strategy followed. The rationale for the use of the gene(s) should be discuss ...
Flu facts - UNSW Health Service
Flu facts - UNSW Health Service

... An estimated 15 per cent of adults and 30 per cent (or more) of young children will be infected annually. Is the flu dangerous? Yes. Influenza is a highly contagious, potentially fatal disease that is estimated to cause between 1,500 and 3,500 deaths each year. This is higher than the national road ...
Vaccine Discovery
Vaccine Discovery

... Venezuelan equine encephalitis virus, Everglades virus and Mucambo virus when administered up to 48h after airborne challenge. Virology 426:100.[PubMedID:22341308] Venezuelan Equine encephalitis virus (VEEV) was previously developed as a biological weapon by several nations and it is currently asses ...
Document
Document

... Data from Phase 1a study ...
Table 1
Table 1

... 6. It can’t be spread by handling used tissues or by drinking from a glass used by an infected person. ...
64th Western Poultry Disease Conference (March 23
64th Western Poultry Disease Conference (March 23

... Health challenges in poultry grown as organic or antibiotic free or in alternate housing Risk factors for antimicrobial resistance of Escherichia coli isolates from Ontario broiler chicken flocks at chick placement: a comparison of three production system types Antimicrobial susceptibility of Clostr ...
Lecture outline : Immunity This is a protective or defense mechanism
Lecture outline : Immunity This is a protective or defense mechanism

... Active and Passive Immunity • Active immunity is resistance acquired after contact with • foreign antigens, eg, microorganisims • This contact may consist of : • Clinical or subclinical infections • Immunization with live or killed infectious agents or their antigens. • Exposure to microbial product ...
Development of Advanced Adjuvants and Immune Modulators
Development of Advanced Adjuvants and Immune Modulators

... TLR4 to NFB interactome overlap  Mechanisms still not well understood but: Adjuvants can either  Act as a depot (focus)  Recruit Immune cells  Activate Immune Cells ...
10_12_immuno~2
10_12_immuno~2

... European history) is by Thucydides (460-404 BC, Athens), who described the great pestilence of 430-429 BC in Athens, during the second year of the Peloponnesian War, an outbreak that killed more than 30,000 people (out of a population of 172,000) – Thucydides noted that those who had recovered would ...
Historical Perspectives (cont.)
Historical Perspectives (cont.)

... Extended this observation to humans and described two types of phagocytic cells circulating in the blood, noted that some fixed cells were also capable of ...
Lymphatic/Immune System
Lymphatic/Immune System

... Fat Absorption – From the Digestive Tract ...
PowerPoint Presentation - I. Introduction to class
PowerPoint Presentation - I. Introduction to class

...  Antigens are introduced in vaccines (immunization).  Body generates an immune response to antigens.  Immunity can be lifelong (oral polio vaccine) or temporary (tetanus toxoid). 2. Artificially Acquired Passive Immunity:  Preformed antibodies (antiserum) are introduced into body by injection. ...
Animal Models of Leishmaniasis Relevant to
Animal Models of Leishmaniasis Relevant to

L13 Classical and variant infectious bronchitis viruses: epidemiology
L13 Classical and variant infectious bronchitis viruses: epidemiology

... new genotypes. Other than the Mass, currently 793B, QX and Q1 IBVs are considered to have significant global impact. Almost every country has their own population of IBVs, some examples being Arkansas, Delaware (GA 07, GA 08) and California in the USA. In addition, IS/885/00 and IS/1494/06 (variant ...
Quantity, not quality, of antibody response decreased in the elderly
Quantity, not quality, of antibody response decreased in the elderly

... induce a robust serum antibody response. In this issue of the JCI, Sasaki et al. identify some of the cellular and molecular deficits that underlie the reduced serum antibody response induced by influenza vaccination in elderly individuals. Importantly, they show that it is the quantity of the respo ...
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Vaccine



A vaccine is a biological preparation that provides active acquired immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing micro-organism and is often made from weakened or killed forms of the microbe, its toxins or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and keep a record of it, so that the immune system can more easily recognize and destroy any of these micro-organisms that it later encounters.The administration of vaccines is called vaccination. The effectiveness of vaccination has been widely studied and verified; for example, the influenza vaccine, the HPV vaccine, and the chicken pox vaccine. Vaccination is the most effective method of preventing infectious diseases; widespread immunity due to vaccination is largely responsible for the worldwide eradication of smallpox and the restriction of diseases such as polio, measles, and tetanus from much of the world. The World Health Organization (WHO) reports that licensed vaccines are currently available to prevent or contribute to the prevention and control of twenty-five infections.Vaccines can be prophylactic (example: to prevent or ameliorate the effects of a future infection by any natural or ""wild"" pathogen), or therapeutic (e.g., vaccines against cancer are also being investigated; see cancer vaccine).The terms vaccine and vaccination are derived from Variolae vaccinae (smallpox of the cow), the term devised by Edward Jenner to denote cowpox. He used it in 1798 in the long title of his Inquiry into the...Variolae vaccinae...known...[as]...the Cow Pox, in which he described the protective effect of cowpox against smallpox. In 1881, to honour Jenner, Louis Pasteur proposed that the terms should be extended to cover the new protective inoculations then being developed.
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