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Introduction to Bioequivalence Studies
Introduction to Bioequivalence Studies

...  Powders for reconstitution as solution  Gases ...
FLUOROPLEX (fluorouracil) 1% Topical Cream DESCRIPTION
FLUOROPLEX (fluorouracil) 1% Topical Cream DESCRIPTION

... General: There is a possibility of increased absorption through ulcerated or inflamed skin.  Information for patients: The medication should be applied with care near the eyes, nose, and mouth.   Excessive reaction in these areas may occur due to irritation from accumulation of drug. FLUOROPLEX®  Cr ...
View Full Text-PDF
View Full Text-PDF

... the studies. For the pharmacological evaluation, the compounds were suspended in water using Tween 80 as a suspending agent. For all the studies, animals were divided into groups of 4 animals. The control group received the calculated amount of normal saline. All the experiments were carried out at ...
CASE REPORT ERYTHROMYCIN INDUCED TORSADE DE
CASE REPORT ERYTHROMYCIN INDUCED TORSADE DE

... erythromycin, where the inhibitory effect of erythromycin caused an increase in methadone concentration and thus causing the adverse effects. In the case above, although concern is raised regarding the inhibitory effect of erythromycin in patients receiving methadone, it is also pertinent to mention ...
ASSESSMENT OF ANTI-INFLAMATORY ACTIVITY OF STATIN Research Article ADENIRAN SANMI ADEKUNLE,
ASSESSMENT OF ANTI-INFLAMATORY ACTIVITY OF STATIN Research Article ADENIRAN SANMI ADEKUNLE,

... Cardiovascular disease is a class of disease that involves the heart or blood vessels (arteries and veins), [1] while the term technically refers to any disease that affects the cardiovascular system. It is usually used to refer to those related to atherosclerosis (arterial disease). These condition ...
$doc.title

... •  64  pa6ents  of  pla6num  resistant  were  enrolled  in  completed  Phase  II  clinical  trial  in  ovarian  cancer.  The   progression  free  survival  (PFS)  rate  at  6  months  was  22%  with  a  median  6me  to  progression  o ...
The Haunting of Medical Journals: How Ghostwriting Sold ``HRT``
The Haunting of Medical Journals: How Ghostwriting Sold ``HRT``

... into how pharmaceutical companies promote drugs, including the use of vendors to produce ghostwritten manuscripts and place them into medical journals. Dozens of ghostwritten reviews and commentaries published in medical journals and supplements were used to promote unproven benefits and downplay ha ...
Development and Evaluation of Enteric Coated Tablet Containing
Development and Evaluation of Enteric Coated Tablet Containing

... compatible in entrapping the selected drug (diclofenac sodium). Among the three different formulas selected for the formulation of core tablet, batch-I was found to be comparatively better, since its physicochemical parameters were found to be within the USP limits. Coating of core tablets using sha ...
Mol Biol Evol-2014-Oz-2387-401
Mol Biol Evol-2014-Oz-2387-401

... drug pairs and biological mechanisms behind drug–drug interactions (Yeh et al. 2006, 2009; Bollenbach et al. 2009; Cokol et al. 2011). Use of synergistic drug pairs, which have higher inhibitory effects compared with each drug’s individual effect, has been particularly important and useful for antib ...
MOTM SULFANILAMIDE - School of Chemistry
MOTM SULFANILAMIDE - School of Chemistry

... Tetracycline (INN) ( /ˌtɛtrəˈsaɪkliːn/) is a broad-spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria, indicated for use against many bacterial infections. It is a protein synthesis inhibitor. It is commonly used to treat acne today, and, more recently, rosacea, and ...
Assessing Statin Therapy: What are Their Differences? - Pri-Med
Assessing Statin Therapy: What are Their Differences? - Pri-Med

... Amit Khera, MD, MSc, FACC, is an associate professor of medicine at the University of Texas, Southwestern Medical School in Dallas, Texas, where he serves as director of the preventive cardiology program and program director for the cardiology fellowship. He is also medical director of cardiac rehab ...
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
UNITED STATES SECURITIES AND EXCHANGE COMMISSION

... Sanofi Genzyme and $3.3 million from the company’s alliance with The Medicines Company. The company expects net revenues from collaborators to increase during the second half of 2016 due to an expected increase in expense reimbursement from Sanofi Genzyme. Research and Development Expenses Research ...
Strengthening Post-Market Safety Surveillance in Low
Strengthening Post-Market Safety Surveillance in Low

... Health Organization (WHO) standards and technical assistance programs, and disease- and productspecific initiatives. The human and financial resources available to strengthen post-market safety surveillance in developing countries are limited. Synergies must be encouraged and reinforced. This strate ...
Article Strength of Selection Pressure Is an
Article Strength of Selection Pressure Is an

... quantifying evolved strains’ resistance levels against chloramphenicol, a protein synthesis inhibitor (Yeh et al. 2006). MIC for the ancestor wild-type strain was measured as approximately 6 mg/ml (fig. 2A, green line with circles) whereas CHLS-2, one of the strains evolved against chloramphenicol u ...
Issues around the Prescription of Half Tablets in Northern
Issues around the Prescription of Half Tablets in Northern

... Quetiapine is an atypical or second-generation antipsychotic agent similar in structure to clozapine and exhibits strong antagonism of 5HT2 receptors and weak antagonism of D2 receptors [12]. It is approved for the treatment of schizophrenia and bipolar disorders [13] and is widely used mainly becau ...
DEVELOPMENT AND VALIDATION OF A RP-HPLC METHOD FOR SIMULTANEOUS
DEVELOPMENT AND VALIDATION OF A RP-HPLC METHOD FOR SIMULTANEOUS

... increased gastrointestinal motility can facilitates the movement of acid contents further down in the intestine preventing reflux esophagitis and in this way control nausea and vomiting. Thus, the pharmacology of Pantoprazole and Cinitapride corroborates their use in combined dosage form to treat va ...
Benzodiazepine usage in the North Eastern Health Board
Benzodiazepine usage in the North Eastern Health Board

... of people over 65 years are dissatisfied with their sleep)[23]. Anxiety is a normal response to stress, and refers to a feeling of fear or apprehension, together with symptoms of increased sympathetic activity. There are several different types of anxiety. The most common include panic disorder, ago ...
Archive 2014
Archive 2014

... The MET Institute of Pharmacy (MET IOP) was established in the year 1993 with the two-year Diploma programme in Pharmacy (D.Pharm.) recognised by the Directorate of Technical Education. The four-year Bachelor's programme in Pharmacy (B.Pharm.) affiliated to the University of Mumbai was started in th ...
Preclinical Screening and Evaluation of Agents
Preclinical Screening and Evaluation of Agents

... animals. In such case, tumor-inhibition assays may be unnecessary. Although the emphasis in survival time assays is on the longevity of treated animals, it is not intended that in such assays toxic manifestations should be overlooked. One would obviously be dubious about accepting as an effective ag ...
Alexander Fleming and the discovery of Penicillin
Alexander Fleming and the discovery of Penicillin

... discovering the world's first antibiotic…” He investigated its positive antibacterial effect on many organisms, and noticed that it affected bacteria such as staphylococci and many other Gram positive pathogens that cause scarlet fever, pneumonia, meningitis and diphtheria, but not typhoid fever or ...
Methamphetamine use in Australia - NCETA
Methamphetamine use in Australia - NCETA

... reported using in the past 12 months (including 0.8% and 0.4% using in the last month and week, respectively) (Fig 1). The highest prevalence of 12 month methamphetamine use was recorded in 1998 at 3.7% (Fig 2). ...
Management of Status Epilepticus D. DURHAM
Management of Status Epilepticus D. DURHAM

... Critical Care and Resuscitation 1999; 1: 344-353 and conduction of an abnormal neural discharge, by using antiepileptic drugs, and eliminating the cause of the seizure, by correcting the metabolic disorder, drug toxicity or structural abnormality (e.g. surgical excision of an epileptic focus in pat ...
Alcohol and Other Drugs: A Handbook for Health Professionals
Alcohol and Other Drugs: A Handbook for Health Professionals

... This Handbook is the third edition of a resource originally produced well over a decade ago. The last edition proved to be a valuable and much sought after document. In the intervening years since the last edition of the Handbook was produced the alcohol and other drugs field has changed, expanded ...
Psilocybin - TU Darmstadt Chemie
Psilocybin - TU Darmstadt Chemie

... On the other hand, the substance could be directly used as anxiolytic or antidepressant in disorders with very low levels of serotonin in the brain. A number of clinical studies with psilocybin exist, but were performed in the 1960s. Scientific papers found positive effects with low side effects, a ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008, p-ISSN:2319-7676.
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008, p-ISSN:2319-7676.

... agents for synergistic therapeutic outcomes. With the adoption of HAART, the average survival of HIV/AIDS patients has increased from less than 1 year to over 10 years [1,2]. The joint United Nations programme on HIV/AIDS (UNAIDS) and World Health Organization (WHO) reported on global AIDS epidemic ...
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Pharmaceutical industry



The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.
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