THEORETICAL STUDY ON PHYSICOCHEMICAL AND GEOMETRICAL PROPERTIES OF THE
... because of their possible use in drug delivery, sensing, imaging and chemotherapy1-6. Au NPs have distinguishing features, for example, their sizes can be simply conducted during combination and their surfaces can be easily functionalized with different kinds of molecules7-10. Properly functionalize ...
... because of their possible use in drug delivery, sensing, imaging and chemotherapy1-6. Au NPs have distinguishing features, for example, their sizes can be simply conducted during combination and their surfaces can be easily functionalized with different kinds of molecules7-10. Properly functionalize ...
06 Antibiotics of the heterocyclic structure
... of this class is nalidyxone acid (nevigramon, negram) and its analogs is a pipemіdine acid (pipemidine, palin, urosept, pimidel). These drugs are characterized primarily by the activity to gramnegative microorganisms, the rapid development of resistance to these antibiotics causing their using only ...
... of this class is nalidyxone acid (nevigramon, negram) and its analogs is a pipemіdine acid (pipemidine, palin, urosept, pimidel). These drugs are characterized primarily by the activity to gramnegative microorganisms, the rapid development of resistance to these antibiotics causing their using only ...
April 23, 2009 Division of Dockets Management Food and Drug
... 505(j) that references a drug product containing an autoinjector as the listed drug, unless it has been demonstrated that the proposed autoinjector is the "same" as the autoinjector in the Reference Listed Drug ("RLD"); 2. Refuse to designate any drug product containing an autoinjector approved unde ...
... 505(j) that references a drug product containing an autoinjector as the listed drug, unless it has been demonstrated that the proposed autoinjector is the "same" as the autoinjector in the Reference Listed Drug ("RLD"); 2. Refuse to designate any drug product containing an autoinjector approved unde ...
Study of Sustained Blood Pressure-Lowering Effect of Azelnidipine
... Azelnidipine is a dihydropyridine calcium antagonist, which was synthesized by Ube Industries, Ltd. and developed by Sankyo Co., Ltd. (now known as Daiichi Sankyo Co., Ltd., Tokyo, Japan). This agent has a potent and sustained BP-lowering effect in various animal models of hypertension [9]. It has a ...
... Azelnidipine is a dihydropyridine calcium antagonist, which was synthesized by Ube Industries, Ltd. and developed by Sankyo Co., Ltd. (now known as Daiichi Sankyo Co., Ltd., Tokyo, Japan). This agent has a potent and sustained BP-lowering effect in various animal models of hypertension [9]. It has a ...
Public Policy Statement on the Use of Naloxone for the
... evaluation or medically necessary treatment. In 2014, the federal Food and Drug Administration fast-tracked approval of a new delivery device for naloxone that can be used by lay persons with virtually no training. Increased awareness of the opioid overdose epidemic in 2014 led to public pronounceme ...
... evaluation or medically necessary treatment. In 2014, the federal Food and Drug Administration fast-tracked approval of a new delivery device for naloxone that can be used by lay persons with virtually no training. Increased awareness of the opioid overdose epidemic in 2014 led to public pronounceme ...
The neural basis of drug craving: an incentive
... posits that addictive behavior is due largely to progressive and persistent neuroadaptations caused by repeated drug use. It is, if you will, a ‘neuroadaptationist model’. It is proposed that these drug-induced changes in the nervous system are manifest both neurochemitally and behaviorally by the p ...
... posits that addictive behavior is due largely to progressive and persistent neuroadaptations caused by repeated drug use. It is, if you will, a ‘neuroadaptationist model’. It is proposed that these drug-induced changes in the nervous system are manifest both neurochemitally and behaviorally by the p ...
Depakote - UnitedHealthcareOnline.com
... -ORc. Documented history of drug-resistant epilepsy (defined as the failure of two tolerated and appropriately chosen and used anti-epileptic drug schedules [as either mono-therapy or combination therapy] to achieve sustained seizure freedom) -ORd. Documented history of a high risk for seizure recu ...
... -ORc. Documented history of drug-resistant epilepsy (defined as the failure of two tolerated and appropriately chosen and used anti-epileptic drug schedules [as either mono-therapy or combination therapy] to achieve sustained seizure freedom) -ORd. Documented history of a high risk for seizure recu ...
Summary of Product Characteristics
... until maximum improvement is obtained. Total daily requirements are usually in the range to 30 – 360mg. The requirement for pyridostigmine is usually markedly decreased after thymectomy or when additional therapy (steroids, immunosuppressant drugs) is given. When relatively large doses of pyridostig ...
... until maximum improvement is obtained. Total daily requirements are usually in the range to 30 – 360mg. The requirement for pyridostigmine is usually markedly decreased after thymectomy or when additional therapy (steroids, immunosuppressant drugs) is given. When relatively large doses of pyridostig ...
VALIDATED ZERO ORDER AND FIRST ORDER DERIVATIVE SPECTROPHOTOMETRIC AZEOTROPIC MIXTURE Original Article
... There was no interference from the excipients commonly present in the tablets. The drug content was found to be 100.01% with a % R.S.D. of 0.14 and 99.93% with a % R.S.D. of 0.37 for zero order and first order derivative spectrophotometric methods respectively. It may therefore be inferred that degr ...
... There was no interference from the excipients commonly present in the tablets. The drug content was found to be 100.01% with a % R.S.D. of 0.14 and 99.93% with a % R.S.D. of 0.37 for zero order and first order derivative spectrophotometric methods respectively. It may therefore be inferred that degr ...
Pharmacokinetic/Pharmacodynamic Parameters: Rationale
... PAE refers to the persistent suppression of bacterial growth following exposure to an antimicrobial [2, 7, 10]. PAE can be considered the time it takes for an organism to recover from the effects of exposure to an antimicrobial; this phenomenon was first described in the 1940s with regard to the act ...
... PAE refers to the persistent suppression of bacterial growth following exposure to an antimicrobial [2, 7, 10]. PAE can be considered the time it takes for an organism to recover from the effects of exposure to an antimicrobial; this phenomenon was first described in the 1940s with regard to the act ...
... competency as the ability of personnel to apply their skill, knowledge, and experience to perform their duties correctly. Laboratory directors, consultants, supervisors, and managers must be assessed on their administrative duties in addition to performing testing. However, the experience of CMS and ...
Presented at ICAAC 2015, San Diego, CA, USA
... Methods. A double-blind, placebo-controlled, single dose escalation study in healthy volunteers. Eligible subjects were aged 18–55 y, male or female of non-childbearing potential. They were assigned to 6 dosing cohorts (80, 160, 320, 480, 640 and 800 mg of Debio 1450), each with 8 subjects (6 random ...
... Methods. A double-blind, placebo-controlled, single dose escalation study in healthy volunteers. Eligible subjects were aged 18–55 y, male or female of non-childbearing potential. They were assigned to 6 dosing cohorts (80, 160, 320, 480, 640 and 800 mg of Debio 1450), each with 8 subjects (6 random ...
Optimized and Validated Spectrophotometric Methods for the
... Three new visible spectrophotometric methods which are simple, sensitive and cost-effective are proposed for the determination of gatifloxacin (GTF) using N-bromosuccinimide (NBS), and three dyes, thymol blue, indigo carmine and methyl orange as reagents. The methods engross the addition of a known ...
... Three new visible spectrophotometric methods which are simple, sensitive and cost-effective are proposed for the determination of gatifloxacin (GTF) using N-bromosuccinimide (NBS), and three dyes, thymol blue, indigo carmine and methyl orange as reagents. The methods engross the addition of a known ...
antiretroviral drug interactions and adverse side effects
... Pharmacy, University of California, San Francisco, School of Pharmacy, San Francisco, California. Address correspondence to: Jennifer Cocohoba, PharmD, Health Sciences Assistant Clinical Professor of Pharmacy, University of California, San Francisco, School of Pharmacy, ...
... Pharmacy, University of California, San Francisco, School of Pharmacy, San Francisco, California. Address correspondence to: Jennifer Cocohoba, PharmD, Health Sciences Assistant Clinical Professor of Pharmacy, University of California, San Francisco, School of Pharmacy, ...
History and progress of antiviral drugs: From acyclovir to direct
... purposes were selected as antiviral candidates, based on their success in other medical disciplines. These methods for antiviral discovery were empirical, and most of the time, the biological mechanism behind the observed antiviral effect remained unclear. For instance, the use of thio-semicarbazone ...
... purposes were selected as antiviral candidates, based on their success in other medical disciplines. These methods for antiviral discovery were empirical, and most of the time, the biological mechanism behind the observed antiviral effect remained unclear. For instance, the use of thio-semicarbazone ...
Stability Testing of Pharmaceutical Products
... bracket tables for prediction of shelf life of the products but these methods are not official either in ICH or FDA. The Q rule states that a product degradation rate decreases by a constant factor Q10 when the storage temperature is decreased by 10°C. The value of Q10 is typically set at 2, 3 or 4 ...
... bracket tables for prediction of shelf life of the products but these methods are not official either in ICH or FDA. The Q rule states that a product degradation rate decreases by a constant factor Q10 when the storage temperature is decreased by 10°C. The value of Q10 is typically set at 2, 3 or 4 ...
Prepared By - Beckman Coulter
... Results are automatically printed for each sample in g/mL at 37°C. Interpretation of Results The factors that can influence the relationship between the phenobarbital serum or plasma concentrations and clinical response include the type and severity of seizures, age, general state of health, and us ...
... Results are automatically printed for each sample in g/mL at 37°C. Interpretation of Results The factors that can influence the relationship between the phenobarbital serum or plasma concentrations and clinical response include the type and severity of seizures, age, general state of health, and us ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... paracetamol combination has central and peripheral action with better anti-inflammatory effect. The fall in temperature at 1 hr was more in Mefenamic acid and paracetamol combination group (102.120F to 99.5oF ) compared with paracetamol group(101.81oF to 100.32oF) These results show that Mefenamic a ...
... paracetamol combination has central and peripheral action with better anti-inflammatory effect. The fall in temperature at 1 hr was more in Mefenamic acid and paracetamol combination group (102.120F to 99.5oF ) compared with paracetamol group(101.81oF to 100.32oF) These results show that Mefenamic a ...
Enhancement of naturally acquired immunity against malaria by
... Mass drug administration (MDA) involves the prescription of antimalarial drugs to whole populations without screening for the presence of parasitaemia. This can be done either directly, when a curative dose of the antimalarial drug is given to an entire population, or indirectly, when the antimalari ...
... Mass drug administration (MDA) involves the prescription of antimalarial drugs to whole populations without screening for the presence of parasitaemia. This can be done either directly, when a curative dose of the antimalarial drug is given to an entire population, or indirectly, when the antimalari ...
New antiarrhythmic agents for atrial fibrillation
... early recurrence of AF after successful cardioversion [11,20,21]. This also seems to be applicable for other calcium antagonists, including diltiazem and dihydropyridines [11]. At the same time, the lack of benefit from long-term treatment with verapamil strongly supports the hypothesis that recover ...
... early recurrence of AF after successful cardioversion [11,20,21]. This also seems to be applicable for other calcium antagonists, including diltiazem and dihydropyridines [11]. At the same time, the lack of benefit from long-term treatment with verapamil strongly supports the hypothesis that recover ...
DEVELOPMENT OF A NEW RP-HPLC METHOD FOR THE ESTIMATION OF... TABLET DOSAGE FORM Research Article
... selected. The retention time for NVP was found as 3.663 min. UV spectra of NVP showed that the drug absorbed maximum at 225 nm, so this wavelength was selected as the detection wavelength. A plot was drawn between concentration of the component and peak area. It was found to be linear in the range o ...
... selected. The retention time for NVP was found as 3.663 min. UV spectra of NVP showed that the drug absorbed maximum at 225 nm, so this wavelength was selected as the detection wavelength. A plot was drawn between concentration of the component and peak area. It was found to be linear in the range o ...
ASYMMETRIC SYNTHESES AND TRANSFORMATIONS с TOOLS
... Further issues, such as environment impact, cost, recovery of chiral catalyst or chiral auxiliary, are of great importance at the production scale but again, these issues can best be assessed when considering each individual chiral target compound. The various methods for chirality multiplication us ...
... Further issues, such as environment impact, cost, recovery of chiral catalyst or chiral auxiliary, are of great importance at the production scale but again, these issues can best be assessed when considering each individual chiral target compound. The various methods for chirality multiplication us ...
Drug effects on salivary glands: dry mouth
... and noradrenaline uptake, as well as a miscellany of other drugs such as appetite suppressants, protease inhibitors and cytokines. CONCLUSION: Dry mouth has a variety of possible causes but drugs – especially those with anticholinergic activity against the M3 muscarinic receptor – are the most commo ...
... and noradrenaline uptake, as well as a miscellany of other drugs such as appetite suppressants, protease inhibitors and cytokines. CONCLUSION: Dry mouth has a variety of possible causes but drugs – especially those with anticholinergic activity against the M3 muscarinic receptor – are the most commo ...
UNITED STATES DISTRICT COURT FOR THE NORTHERN
... Carpenters and the proposed classes allege two bases for defendant’s liability. ...
... Carpenters and the proposed classes allege two bases for defendant’s liability. ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.