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Heart failure with preserved ejection fraction (HFPEF).
Heart failure with preserved ejection fraction (HFPEF).

... and given the neutral result of many large trials on HFPEF, further studies are still necessary11,12. True cardiac hypertrophy has little in common with limited myocardial infarction, and in both conditions, the underlying mechanisms that drive LV remodeling are likely to be different and, actually, ...
Human Physiology/The cardiovascular system
Human Physiology/The cardiovascular system

... The two atrioventricular (AV) valves are one-way valves that ensure that blood flows from the atria to the ventricles, and not the other way. The two semilunar (SL) valves are present in the arteries leaving the heart; they prevent blood from flowing back into the ventricles. The sound heard in a he ...
Ventricles - science-b
Ventricles - science-b

...  Blood is pumped out of right side through the pulmonary trunk, which splits into pulmonary arteries and takes oxygen-poor blood to lungs  Oxygen-rich blood returns to the heart from the lungs via pulmonary veins ...
3. carditis
3. carditis

... adults, severe forms occur in young children. Carditis frequency increases significantly during epidemics of viral infections. Etiology and pathogenesis. Carditis may be complicated by any infectious disease, regardless of the causative agent. However, in most cases MN arise in children with acute ...
- Wiley Online Library
- Wiley Online Library

... However, the extent of each of these findings varies from patient to patient.3,4,21 The diagnosis of ventricular noncompaction commonly is facilitated by echocardiographic criteria. These include assessment of the compacted (normal) outer myocardial layer toward the epicardium relative to trabeculate ...
ASE/SCA Guidelines for Performing a Comprehensive
ASE/SCA Guidelines for Performing a Comprehensive

... descending; Cx, circumflex; RCA, right coronary artery. ...
Physiology of the Right Ventricle
Physiology of the Right Ventricle

... Measurements of systolic function are ideally load-independent, which means constancy over a wide range of immediate changes in preload or afterload. The requirement is met with an acceptable approximation by Emax in intact hearts. This is because Emax is the only point of the pressure–volume curve ...
Acute right ventricular failure—from pathophysiology to new
Acute right ventricular failure—from pathophysiology to new

... from the right atria to the lungs, continuously emptying the right atria. This ‘continuous’ ejection is possible because of the favourable characteristics of the pulmonary vascular bed, which is a low pressure, low resistance and high compliance circuit with a pressure gradient of 5 mmHg. Conversely ...
Isolated Cat Trabeculae in a Simulated Feline Heart and Arterial
Isolated Cat Trabeculae in a Simulated Feline Heart and Arterial

... changed the polarity of the electrodes every impulse. We have used for this study muscles with cross-sectional areas less than 0.06 mm2 (Table 1). The following arguments can be put forward to support the idea that the performance of such small muscles under these conditions is not limited by diffus ...
Acute right ventricular failure–– from pathophysiology to new
Acute right ventricular failure–– from pathophysiology to new

... tool enabling clinical assessment of right ventricular volume and haemodynamic parameters by thermodilution. It may also measure cardiac output more precisely even in the presence of tricuspid insufficiency, a particular problem during mechanical ventilation. Indeed, the more widespread introduction ...
Diastolic Dysfunction and Its Management in Elderly Patients
Diastolic Dysfunction and Its Management in Elderly Patients

... ventriculography, or contrast ventriculography will be needed to determine whether CHF is caused by systolic or diastolic dysfunction, because these tests can estimate left ventricular size and function. When a patient has dyspnea or pulmonary edema, conditions such as mitral stenosis and noncardiog ...
Assessment of longitudinal left ventricular systolic function by
Assessment of longitudinal left ventricular systolic function by

... tethering effects than Doppler tissue imaging, but it is markedly load-dependent (8). Different from S and SR rate, TDV is dependent of whole heart translation and tethering (9). Although some analysts claim that myocardial SR imaging is a superior method for the evaluation of longitudinal left vent ...
as a PDF
as a PDF

... the heart contractility and pressure via vasodialatation. Its acute administration in the chick embryo exhibits dose-dependent lethality (Ostadal et al., 1987) and results in general growth retardation. It is not yet clear whether it is a direct systemic effect (Jaffee & Jaffee, 1989) or a result of ...
Pulmonary arterial disease with multifocal dissecting
Pulmonary arterial disease with multifocal dissecting

... than the aorta, Watson (1956) could find reports of only four cases involving the pulmonary arteries. Since that review there have been a few further isolated reports such as those of Fleming (1956), Foord and Lewis (1959), and Ravines (1960). Such cases are, however, rather different from that desc ...
PDF - Circulation: Arrhythmia and Electrophysiology
PDF - Circulation: Arrhythmia and Electrophysiology

... Circ Arrhythm Electrophysiol is available at http://circep.ahajournals.org ...
Relation Between Mural Force and Pressure in the Left Ventricle of
Relation Between Mural Force and Pressure in the Left Ventricle of

... Linzbach11 calculated that the force would be lower at the end of ejection than at the beginning, as is actually seen in figure 3. This is not invariably true, however, for when the stroke volume is small, no decline or even a slight increase in tension may occur. Figure 4 shows the relationship bet ...
A comparative study of contractility of the heart ventricle in some
A comparative study of contractility of the heart ventricle in some

... parts were found to be significant between the animals examined. The electromechanical delay in tortoises was shorter than in the other two species. The isovolumetric contraction time in frogs was approximately twofold longer than in both reptiles. As a consequence, the longest pre-ejection period w ...
PDF - Circulation
PDF - Circulation

... the great arteries. This type of great vessel arrangement has not been reported in truncus arteriosus. The present case report is illustrative of what we believe to be the simultaneous presence of "common truncus" and transposition of the great vessels. ...
Print - Circulation: Cardiovascular Imaging
Print - Circulation: Cardiovascular Imaging

... cardiac Data analysis was done with View Forum software (release 6.1, Philips, Best, The Netherlands). Antegrade and retrograde flows were measured as described elsewhere.12, 15 Aorto-pulmonary collateral flow (mL) was defined as the difference between effective antegrade aortic flow and the sum of ...
Prenatal diagnosis of total anomalous pulmonary venous
Prenatal diagnosis of total anomalous pulmonary venous

... frequently seen as part of the complex cardiac heterotaxy syndrome, especially as part of right atrial isomerism syndrome. Prenatal diagnosis of TAPVC is beneficial, because affected neonates can deteriorate very rapidly after delivery and surgical treatment can be planned. Visualization of pulmonar ...
Spontaneous Aortic Regurgitation and Valvular Cardiomyopathy in
Spontaneous Aortic Regurgitation and Valvular Cardiomyopathy in

... but did not protect valve function. There was significant left ventricular volume overload, hypertrophy, and fetal gene expression, at all ages in Wave mice with aortic regurgitation. Left ventricular systolic function was normal until 6 months of age in Wave mice, but became impaired by 12 months o ...
An adaptive singular spectrum analysis approach to murmur
An adaptive singular spectrum analysis approach to murmur

... usually is constant throughout systolic ejection, often radiating to the axilla. The harshness of the murmur does not correlate with the magnitude of the valvular defect. Patients with severe disease often have a third heart sound. In acute mitral regurgitation, the examination usually is consistent ...
Total heart volume variation throughout the cardiac cycle in humans
Total heart volume variation throughout the cardiac cycle in humans

... These studies confirm the presence, but an unclear extent and timing, of total heart volume variation throughout the cardiac cycle at rest. Additional physiological information may be obtained using measurements of blood flow that are easily obtained using MRI. Therefore, the goals of this study wer ...
Impacts of aortic stenosis and hypertension on left ventricular
Impacts of aortic stenosis and hypertension on left ventricular

... in comparison with aortic stenosis. Such an investigation is very difficult to perform in patients because of the implications of numerous mechanical, hormonal and neurogenic factors. In this study, we focused on the mechanical aspects by considering a hypothetical asymptomatic patient whose left ven ...
ventricular weight in cardiac hypertrophy - Heart
ventricular weight in cardiac hypertrophy - Heart

... the objection that a large and varying proportion of the weight is accounted for by structures other than the myocardium, and the thickness of the ventricular wall is not a satisfactory criterion because it may be greatly modified by dilatation of the cavity. The traditional methods are particularly ...
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Mitral insufficiency



Mitral insufficiency (MI), mitral regurgitation or mitral incompetence is a disorder of the heart in which the mitral valve does not close properly when the heart pumps out blood. It is the abnormal leaking of blood backwards from the left ventricle, through the mitral valve, into the left atrium, when the left ventricle contracts, i.e. there is regurgitation of blood back into the left atrium. MI is the most common form of valvular heart disease.
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