Transgenic expression of ZBP1 in neurons suppresses cocaine-associated conditioning
... and Bassell 2011). To facilitate studies of transgene expression we used a GFP-ZBP1 fusion, with a FLAG epitope at the N terminus of ZBP1. These tags have no effect on ZBP1 protein function (Farina et al. 2003; Tiruchinapalli et al. 2003). We used a doxycycline-regulated transcription system to phar ...
... and Bassell 2011). To facilitate studies of transgene expression we used a GFP-ZBP1 fusion, with a FLAG epitope at the N terminus of ZBP1. These tags have no effect on ZBP1 protein function (Farina et al. 2003; Tiruchinapalli et al. 2003). We used a doxycycline-regulated transcription system to phar ...
input output - Brian Nils Lundstrom
... Three types of steady state neuron responses First, we considered the case when the time-varying stimuli had steady state stimulus statistics, that is, how action potential generation depended on the stimulus’s statistical properties when those properties were fixed, i.e. they did not change in time ...
... Three types of steady state neuron responses First, we considered the case when the time-varying stimuli had steady state stimulus statistics, that is, how action potential generation depended on the stimulus’s statistical properties when those properties were fixed, i.e. they did not change in time ...
Neuroscience Flash Cards, Second Edition
... discourse on esoterica. Until the student develops a solid “overview” of the field, and is able to place structures, pathways, systems, symptoms, and neurological phenomena into proper context, the large references will be confusing and more trouble than they are worth. Most students want to “cut to ...
... discourse on esoterica. Until the student develops a solid “overview” of the field, and is able to place structures, pathways, systems, symptoms, and neurological phenomena into proper context, the large references will be confusing and more trouble than they are worth. Most students want to “cut to ...
Nervous System
... or change established behavior patterns. That's why many scientists believe it's important to keep challenging your brain to learn new things and make new connections — it helps keep the brain active over the course of a lifetime. ...
... or change established behavior patterns. That's why many scientists believe it's important to keep challenging your brain to learn new things and make new connections — it helps keep the brain active over the course of a lifetime. ...
November 2000 Volume 3 Number Supp pp 1184
... (Fig. 3). These results emphasize the critical importance of NMDA currents to normal synaptic function, apart from their contribution to synaptic plasticity. In contrast, increasing the relative contribution of AMPA versus NMDA receptor currents leads to more synchronized and less robust delay activ ...
... (Fig. 3). These results emphasize the critical importance of NMDA currents to normal synaptic function, apart from their contribution to synaptic plasticity. In contrast, increasing the relative contribution of AMPA versus NMDA receptor currents leads to more synchronized and less robust delay activ ...
Worksheet - Nervous System I Lecture Notes Page
... branches called _________________________, but all axons have numerous branches at their ends called ______________ _____________________________. Changes in organelles reflect the special needs of these cells, for example ___________________ help reinforce from within, and _____________ bodies are ...
... branches called _________________________, but all axons have numerous branches at their ends called ______________ _____________________________. Changes in organelles reflect the special needs of these cells, for example ___________________ help reinforce from within, and _____________ bodies are ...
MS Word Version
... Page 7. Signals Are Received At Synapses • The dendrites and cell body provide a large surface area for communication with other neurons. • Signals from other neurons are received at synapses, the junctions between neurons. • Label the synapse in this diagram: ...
... Page 7. Signals Are Received At Synapses • The dendrites and cell body provide a large surface area for communication with other neurons. • Signals from other neurons are received at synapses, the junctions between neurons. • Label the synapse in this diagram: ...
The Nervous System
... Fovea centralis – area of the retina with only cones Respond best in bright light No photoreceptor cells are at the optic disk, or blind spot ...
... Fovea centralis – area of the retina with only cones Respond best in bright light No photoreceptor cells are at the optic disk, or blind spot ...
2002-2003 - Parkinson Canada
... Lay Summary: The cause of Parkinson's disease remains unknown. For several decades, environmental factors were thought to be primarily responsible for causing the death of the cells that produce dopamine. However, recently investigators from around the world have identified specific changes in certa ...
... Lay Summary: The cause of Parkinson's disease remains unknown. For several decades, environmental factors were thought to be primarily responsible for causing the death of the cells that produce dopamine. However, recently investigators from around the world have identified specific changes in certa ...
Neural Networks - School of Computer Science
... Adaptation to changing environment, and emergence of “intelligent” information processing functions by selforganisation, in response to data. ...
... Adaptation to changing environment, and emergence of “intelligent” information processing functions by selforganisation, in response to data. ...
Fifty years of CPGs: two neuroethological papers that shaped BEHAVIORAL NEUROSCIENCE
... feedback and intact descending control from “higher centers” (Grillner, 1975, 1981; Clarac, 2008). Hughes and Wiersma (1960) and Wilson (1961) contradicted that consensus. The Discussions of both papers explicitly addressed this contradiction, and pointed out the broad significance of their results. ...
... feedback and intact descending control from “higher centers” (Grillner, 1975, 1981; Clarac, 2008). Hughes and Wiersma (1960) and Wilson (1961) contradicted that consensus. The Discussions of both papers explicitly addressed this contradiction, and pointed out the broad significance of their results. ...
Parts of the Nervous System
... Node of Ranvier – Gaps in the myelin sheath, allows salutatory conduction to occur Nucleus - Organelle in the cell body of the neuron that contains the genetic material of the cell Schwann's Cells - Cells that produce myelin - they are located within the myelin sheath. ...
... Node of Ranvier – Gaps in the myelin sheath, allows salutatory conduction to occur Nucleus - Organelle in the cell body of the neuron that contains the genetic material of the cell Schwann's Cells - Cells that produce myelin - they are located within the myelin sheath. ...
type Senile Dementia
... Mn-SOD was visualized in both normal and ATD subjects as granular or rodshape immuno-precipitates (Fig. 1A), possibly corresponding to mitochondria as shown in the rat brain (6). Cells with very strong Mn-SOD immunoreactivity were frequently found in the peripheral portion of senile plaques in the c ...
... Mn-SOD was visualized in both normal and ATD subjects as granular or rodshape immuno-precipitates (Fig. 1A), possibly corresponding to mitochondria as shown in the rat brain (6). Cells with very strong Mn-SOD immunoreactivity were frequently found in the peripheral portion of senile plaques in the c ...
Document
... inhibits other muscles. • Multiple neurons can activate the same muscle. • The “motor field” of a cortical motor neuron has to do with organized movements rather than specific muscle groups. ...
... inhibits other muscles. • Multiple neurons can activate the same muscle. • The “motor field” of a cortical motor neuron has to do with organized movements rather than specific muscle groups. ...
Crosstalk between 2 organelles: Lysosomal storage of heparan
... differences between the mouse groups: significant differences between the mean values in Bonferroni post-test (*P < 0.05, **P < 0.001, ***P < 0.0001) are shown. (B) Purkinje cells are largely absent in the lobule III of the anterior cerebellar lobe of Hgsnat-Geo mouse at the age of 12 months. H&E sta ...
... differences between the mouse groups: significant differences between the mean values in Bonferroni post-test (*P < 0.05, **P < 0.001, ***P < 0.0001) are shown. (B) Purkinje cells are largely absent in the lobule III of the anterior cerebellar lobe of Hgsnat-Geo mouse at the age of 12 months. H&E sta ...
Cross-talk between nervous and immune systems
... Communication between neuroendocrine and immune systems requires anatomical connections with direct contact between nervous and immune cells, as well as the presence of receptors on the immune cells for the transmission of the signals. This interaction is mediated, at least in part, by neurotransmit ...
... Communication between neuroendocrine and immune systems requires anatomical connections with direct contact between nervous and immune cells, as well as the presence of receptors on the immune cells for the transmission of the signals. This interaction is mediated, at least in part, by neurotransmit ...
中樞神經系統
... Broca’s area speech production Lateral prefrontal cortex language comprehension and ...
... Broca’s area speech production Lateral prefrontal cortex language comprehension and ...
Chapter 16: Neural Integration II: The Autonomic Nervous System
... – stimulation of sexual glandsSexual arousal: – stimulation of sexual glands ...
... – stimulation of sexual glandsSexual arousal: – stimulation of sexual glands ...
Notes on Learning to Compute and Computing to Learn
... sites where multimodal integration actually takes place [10] – these studies were inspired, in part, by the earlier work on cats [21, 22]. Two experiments, one dealing with subjects’ mouth movements whilst looking at a videotape of the lower half of a face silently mouthing ...
... sites where multimodal integration actually takes place [10] – these studies were inspired, in part, by the earlier work on cats [21, 22]. Two experiments, one dealing with subjects’ mouth movements whilst looking at a videotape of the lower half of a face silently mouthing ...
Distributed Processing of Sensory Information in
... Moderate mechanical stimulation of the body surfaceof the leechcausesa localized withdrawal from the site of stimulation (Kristan et al., 1982;Fig. 1). This is accomplishedby contraction of longitudinal musclesat the stimulated site, and relaxation of those on the opposite side of the body, resultin ...
... Moderate mechanical stimulation of the body surfaceof the leechcausesa localized withdrawal from the site of stimulation (Kristan et al., 1982;Fig. 1). This is accomplishedby contraction of longitudinal musclesat the stimulated site, and relaxation of those on the opposite side of the body, resultin ...
The Science of Psychology
... • Resting potential - the state of the neuron when not firing a neural impulse. • Action potential - the release of the neural impulse • All-or-none - referring to the fact that a neuron either fires completely or does not fire at all. Menu ...
... • Resting potential - the state of the neuron when not firing a neural impulse. • Action potential - the release of the neural impulse • All-or-none - referring to the fact that a neuron either fires completely or does not fire at all. Menu ...
Nervous System - healthsciencesMBIT
... The nervous system carries information from one part of the body to another The nervous system transmit information by nerve impulses to communicate with other parts of the body Main parts of the nervous system are the: Brain, Spinal Cord, and Nerves Regulate homeostasis and responds to disease ...
... The nervous system carries information from one part of the body to another The nervous system transmit information by nerve impulses to communicate with other parts of the body Main parts of the nervous system are the: Brain, Spinal Cord, and Nerves Regulate homeostasis and responds to disease ...
HIPPOCAMPUS
... dentate gyrus (DG) and the Ammons’s horn (AH)may fold during progressively later stages to assume the shape illustrated in the subsequent figure. AC-choroideal area; CG-cingulate gyrus; ENT-entorhinal area; HR-hippocampal rudiment; HY-hypothalamus; LT-lamina terminalis; P-pallium; PA-parasubiculum; ...
... dentate gyrus (DG) and the Ammons’s horn (AH)may fold during progressively later stages to assume the shape illustrated in the subsequent figure. AC-choroideal area; CG-cingulate gyrus; ENT-entorhinal area; HR-hippocampal rudiment; HY-hypothalamus; LT-lamina terminalis; P-pallium; PA-parasubiculum; ...
The endogenously active brain - William Bechtel
... Cognitive activity is assumed to begin with the presentation of a task or stimulus, which is represented and the representation is then transformed via operations specified by the architecture. This reactive ...
... Cognitive activity is assumed to begin with the presentation of a task or stimulus, which is represented and the representation is then transformed via operations specified by the architecture. This reactive ...
ch 16 sensory motor systems
... consists of four stages, each of which gradually merges into the next. Each stage has been identified by EEG recordings . 2) Most dreaming occurs during rapid eye movement sleep. C. Learning and Memory 1. Learning is the ability to acquire new knowledge or skills through instruction or experience. M ...
... consists of four stages, each of which gradually merges into the next. Each stage has been identified by EEG recordings . 2) Most dreaming occurs during rapid eye movement sleep. C. Learning and Memory 1. Learning is the ability to acquire new knowledge or skills through instruction or experience. M ...
Optogenetics
Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.