Pharmacokinetics in pregnancy
... absorbed, distributed and eliminated and how these processes determine plasma concentrations of the drug. The therapeutic actions of most drugs, and often their adverse eects, are determined by the concentration of the drug in plasma. An understanding of pharmacokinetics is thus essential in determ ...
... absorbed, distributed and eliminated and how these processes determine plasma concentrations of the drug. The therapeutic actions of most drugs, and often their adverse eects, are determined by the concentration of the drug in plasma. An understanding of pharmacokinetics is thus essential in determ ...
Uniseed Overview and Investments November 2014 1
... • Over 600 media releases and news articles have been published on Uniseed investee companies; and • Over 200 presentations have been made at conferences or industry seminars, or in industry magazines, based on ...
... • Over 600 media releases and news articles have been published on Uniseed investee companies; and • Over 200 presentations have been made at conferences or industry seminars, or in industry magazines, based on ...
Design and Evaluation of Diclofenac Sodium Ocusert
... toxicity test did not show any signs of irritations or inflammations. The results of accelerated stability studies indicate that they are stable both physically and chemically at 40 C and 370 C. The period of expiry for the formulation F3 was determined by FREE and BLYTHE method. By this method it i ...
... toxicity test did not show any signs of irritations or inflammations. The results of accelerated stability studies indicate that they are stable both physically and chemically at 40 C and 370 C. The period of expiry for the formulation F3 was determined by FREE and BLYTHE method. By this method it i ...
The Pharmaceutical Industry Presented to Geoffrey Poitras Bus 417
... Phase 1: Drug given to a small number of healthy people to test its safety ...
... Phase 1: Drug given to a small number of healthy people to test its safety ...
6. 7. 8. BRIEF RESUME OF THE INTENDED WORK ENCLOSURE
... screening studies of new chemical entities as well as in formulation design and development.3 Nowadays, so many techniques are available for an enhancement of poorly soluble drugs such as the cosolvency, pH adjustment, surfactant addition, solid dispersion and complexation etc. These are the most co ...
... screening studies of new chemical entities as well as in formulation design and development.3 Nowadays, so many techniques are available for an enhancement of poorly soluble drugs such as the cosolvency, pH adjustment, surfactant addition, solid dispersion and complexation etc. These are the most co ...
Nehru Arts and Science College-TM palayam, Coimbatore 105 III B
... 1 .A nonobiosensor that analyzes a biological system is called (a) Transducer (b) bioreceptor (c) detector (d) sensor 2. First report on nanobiosensor was during (a) 1916 (b) 1956 (c) 1962 (d) 1969 3. Diameter of a nanotip sensor is (a) 20 nm (b) 30 nm (c) 40 nm (d) 10 nm 4. The sensing element pres ...
... 1 .A nonobiosensor that analyzes a biological system is called (a) Transducer (b) bioreceptor (c) detector (d) sensor 2. First report on nanobiosensor was during (a) 1916 (b) 1956 (c) 1962 (d) 1969 3. Diameter of a nanotip sensor is (a) 20 nm (b) 30 nm (c) 40 nm (d) 10 nm 4. The sensing element pres ...
RIFAMPIN
... Most of tubercle bacilli are intracellular with slow growth rate. Resistant strains occur naturally to any drug given alone So: (1)combination therapy, at least two effective drugs and sometimes up to four agents are used to prevent emergence of resistant strains. (2)Treatment must be continued long ...
... Most of tubercle bacilli are intracellular with slow growth rate. Resistant strains occur naturally to any drug given alone So: (1)combination therapy, at least two effective drugs and sometimes up to four agents are used to prevent emergence of resistant strains. (2)Treatment must be continued long ...
Unmet Needs in Drug Delivery Technologies
... functions, limit the drug dose that ultimately reaches the target site. Accordingly, many drugs fail to reach their full therapeutic potential. Our research aims at developing a fundamental understanding of body’s key biological barriers such as skin and intestinal epithelium, and utilizing this und ...
... functions, limit the drug dose that ultimately reaches the target site. Accordingly, many drugs fail to reach their full therapeutic potential. Our research aims at developing a fundamental understanding of body’s key biological barriers such as skin and intestinal epithelium, and utilizing this und ...
Metabolic Transformations of Xenobiotics
... • Biotransformation is the process by which a drug is chemically altered by the body. • The liver is the principal, but not the only, site of drug biotransformation. The liver has enzymes that facilitate chemical reactions such as oxidation, reduction, and hydrolysis of drugs (phase I). It has other ...
... • Biotransformation is the process by which a drug is chemically altered by the body. • The liver is the principal, but not the only, site of drug biotransformation. The liver has enzymes that facilitate chemical reactions such as oxidation, reduction, and hydrolysis of drugs (phase I). It has other ...
Mylan Laboratories Inc. (MYL)
... gives greater exposure to cheap labor and lucrative Asia and European markets ...
... gives greater exposure to cheap labor and lucrative Asia and European markets ...
Significance of the Apparent Volume of Distribution
... of Distribution • The apparent volume of distribution is not a true physiologic volume. Most drugs have an apparent volume of distribution smaller than, or equal to, the body mass. For some drugs, the volume of distribution may be several times the body mass. • The apparent VD is dependent on CPo • ...
... of Distribution • The apparent volume of distribution is not a true physiologic volume. Most drugs have an apparent volume of distribution smaller than, or equal to, the body mass. For some drugs, the volume of distribution may be several times the body mass. • The apparent VD is dependent on CPo • ...
Inhalant Abuse: A Curse to the New Generation
... Drug addiction basically is a complex brain disease. supplying harmful substances to children [2]. It is characterized by compulsive, at times uncontrollable, drug craving, seeking and use that World vision India was able to serve 1000 children persist even in the face of severe negative living in t ...
... Drug addiction basically is a complex brain disease. supplying harmful substances to children [2]. It is characterized by compulsive, at times uncontrollable, drug craving, seeking and use that World vision India was able to serve 1000 children persist even in the face of severe negative living in t ...
Drug removal rate
... drug is excreted into the urine (not secreted or reabsorbed in the tubules), then the rate of drug excretion (refers to urine) is the same as the drug removal rate at the glomerulus, or: CLrenal = fu x GFR, and if the drug is unbound (fu = 1), then the renal clearance for the drug is the same as the ...
... drug is excreted into the urine (not secreted or reabsorbed in the tubules), then the rate of drug excretion (refers to urine) is the same as the drug removal rate at the glomerulus, or: CLrenal = fu x GFR, and if the drug is unbound (fu = 1), then the renal clearance for the drug is the same as the ...
Spinout Equinox Pharma speeds up and reduces the cost of drug
... Existing high-throughput conventional screening is expensive and limited to a few compounds at a time. Computer-based virtual screening does not have these limitations, but not all in silico approaches are as effective as the one developed by Equinox. Some only achieve a 15% (or lower) hit rate, whe ...
... Existing high-throughput conventional screening is expensive and limited to a few compounds at a time. Computer-based virtual screening does not have these limitations, but not all in silico approaches are as effective as the one developed by Equinox. Some only achieve a 15% (or lower) hit rate, whe ...
Antiallergic agents
... of bronchial asthma ( As inhalers to prevent asthma attack). Allergic rhinitis (as nasal sprays). Allergic conjunctivitis (as eye drops). Drugs only help prevent them - and they work best if and only if you use their regularly, and if you start using it well before (like 2-4 weeks before) the ...
... of bronchial asthma ( As inhalers to prevent asthma attack). Allergic rhinitis (as nasal sprays). Allergic conjunctivitis (as eye drops). Drugs only help prevent them - and they work best if and only if you use their regularly, and if you start using it well before (like 2-4 weeks before) the ...
Retina Today - October 2011
... of the eye in order to deliver effective treatment for debilitating retinal diseases. To widen the available treatment options, several new drug delivery systems are in development to help reach zero-order kinetics and other characteristics of a successful system (see “Characteristics of a Successfu ...
... of the eye in order to deliver effective treatment for debilitating retinal diseases. To widen the available treatment options, several new drug delivery systems are in development to help reach zero-order kinetics and other characteristics of a successful system (see “Characteristics of a Successfu ...
Principles of Pharmacology
... The time to reach steady-state is 4 - 5 times t1/2 for most of the drugs At steady state : Rate in (dosing rate) = Rate out (elimination) Therefore : Maintenance dose = CL x Cp Steady-state concentration (Css) ...
... The time to reach steady-state is 4 - 5 times t1/2 for most of the drugs At steady state : Rate in (dosing rate) = Rate out (elimination) Therefore : Maintenance dose = CL x Cp Steady-state concentration (Css) ...
Case Study - UCLA K30 Program
... Definition of a Nutraceutical: "Food, or parts of food, that provide medical or health benefits, including the prevention and treatment of disease.”Dr Stephen DeFelice (Foundation for Innovation in Medicine)-coined the term "Nutraceutical" from "Nutrition" and "Pharmaceutical" in 1989. The term nutr ...
... Definition of a Nutraceutical: "Food, or parts of food, that provide medical or health benefits, including the prevention and treatment of disease.”Dr Stephen DeFelice (Foundation for Innovation in Medicine)-coined the term "Nutraceutical" from "Nutrition" and "Pharmaceutical" in 1989. The term nutr ...
Medical Errors: Definition, Causes, and Prevention
... number of patients: “The law of three” – In order to detect for sure SAE that occurs as 1 event per 2000 patients treated we need to treat • 6000 patients • 9600 patients • 13000 patients ...
... number of patients: “The law of three” – In order to detect for sure SAE that occurs as 1 event per 2000 patients treated we need to treat • 6000 patients • 9600 patients • 13000 patients ...
Treatment of Cough - Medicine Batch 2013
... 1. Drugs that may alter mucociliary factors. 2. Drugs acting on the afferent limb. 3. Drugs acting on the cough center. 4. Drugs acting on the efferent limb. 5. Drugs acting on the respiratory skeletal muscles: – Nondepolarizing blockers like pancuronium. – May be considered in patients who can not ...
... 1. Drugs that may alter mucociliary factors. 2. Drugs acting on the afferent limb. 3. Drugs acting on the cough center. 4. Drugs acting on the efferent limb. 5. Drugs acting on the respiratory skeletal muscles: – Nondepolarizing blockers like pancuronium. – May be considered in patients who can not ...
Substance Abuse - Tennessee Dental Hygienist`s Association
... In 2003, an estimated 21.6 million Americans aged 12 or older were classified as having substance dependence or addiction. A December 2011 news release of NIH survey data conducted by the University of Michigan regarding drug use in adolescents (http://www.drugabuse.gov/related‐topics/trends‐statist ...
... In 2003, an estimated 21.6 million Americans aged 12 or older were classified as having substance dependence or addiction. A December 2011 news release of NIH survey data conducted by the University of Michigan regarding drug use in adolescents (http://www.drugabuse.gov/related‐topics/trends‐statist ...
nicotinic receptors
... there are also other drugs which are reversible inhibitors of Ach-esterase When do we need more Ach? One of the conditions where we need more Ach is mysthenia gravis disease: It's an autoimmune disease caused by antibodies to the nicotinic receptors at the neuromuscular junction. So we have destruct ...
... there are also other drugs which are reversible inhibitors of Ach-esterase When do we need more Ach? One of the conditions where we need more Ach is mysthenia gravis disease: It's an autoimmune disease caused by antibodies to the nicotinic receptors at the neuromuscular junction. So we have destruct ...
CURRENT STATUS OF DESIGNER DRUGS
... Title II of Comprehensive Drug Abuse Prevention and Control Act of 1970 Scheduled Drugs – I, II, III, IV, V Schedule depends on medical utility and abuse potential ...
... Title II of Comprehensive Drug Abuse Prevention and Control Act of 1970 Scheduled Drugs – I, II, III, IV, V Schedule depends on medical utility and abuse potential ...
Institutional Review Board
... Emergency Use Drug or Biologic Policy) 2. There is no comparable or satisfactory alternative drug or other therapy available to treat that stage of the disease in the intended patient population. 3. The drug is under investigation in a controlled clinical trial under an IND in effect for the trial, ...
... Emergency Use Drug or Biologic Policy) 2. There is no comparable or satisfactory alternative drug or other therapy available to treat that stage of the disease in the intended patient population. 3. The drug is under investigation in a controlled clinical trial under an IND in effect for the trial, ...