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AACE, TES, ATA Joint Position Statement on the Use and
AACE, TES, ATA Joint Position Statement on the Use and

... significant impact on serum TSH levels, but in certain clinical settings, such as the elderly with cardiac disease or pregnancy, the impact may be clinically highly significant. In fact, this is the basis for manufacturing multiple thyroxine doses. For example, the difference between 137 mcg of thyr ...
Pharmacokinetics
Pharmacokinetics

... • Cell Membranes: This barrier is permeable to many drug molecules but not to others, depending on their lipid solubility. Small pores, 8 angstroms, permit small molecules such as alcohol and water to pass through. • Walls of Capillaries: Pores between the cells are larger than most drug molecules, ...
A. Glucocorticoid drugs
A. Glucocorticoid drugs

... carditis, rhumatic arthritis, rheumatoid arthritis, osteoarthritis, systemic lupus erythematosus, polyarthritis nodosa, nephritic syndrome, etc. ...
cns – antiepileptic drugs
cns – antiepileptic drugs

...  b. assigning an assistant to stay with the patient at all times.  c. keeping an airway available to insert as needed.  d. instructing the patient to stay in bed and call for assistance to go to the bathroom. ...
Pharmacological Approaches to Stuttering
Pharmacological Approaches to Stuttering

... Increased levels of dopamine in the striatum contribute to an abnormal number of disfluencies. ...
Medical Billing and Coding Program
Medical Billing and Coding Program

... eye, nose, etc. Depending upon the practice setting, a Pharmacy Technician is also involved in the admixture of drugs for intravenous use. Other duties include: ...
Drug Induced Liver Injury (DILI) - The University of North Carolina at
Drug Induced Liver Injury (DILI) - The University of North Carolina at

... 2). Biomarkers that are cheap, safe, and ...
Drug Absorption
Drug Absorption

... • The drugs administration by oral route have to get absorbed across the mucous membrane of gastrointestinal tract to enter the circulation. The action of drug depends on the rate as well as the extent of absorption. • The formulation of the drug and its solubility will influence the absorption. Apa ...
Respiratory System
Respiratory System

... Used for symptomatic treatment of bronchospasm, providing quick relief of acute bronchoconstriction. β2 Agonists have no anti-inflammatory effects, and they should never be used as the sole therapeutic agents for patients with persistent asthma. Monotherapy with short-acting β2 agonists may be appro ...
Testing for Overdose of Acetaminophen
Testing for Overdose of Acetaminophen

... and excreted via the kidneys and can be detected in urine for several days after an exposure. While there is a lack of correlation between urine drug concentration and impairment, urine drug screening offers the advantages of noninvasive collection and relatively easy, cost-effective, proven detecti ...
Counterfeit medicines in less developed countries
Counterfeit medicines in less developed countries

... with diethylene glycol (a chemical commonly used as anti-freeze). This particular product was made in China, transported through a Dutch company to Germany, before winding up on the Haitian market. A similar case occurred in Nigeria in 1995, resulting in the death of 109 children and again in Bangla ...
DEVELOPMENT AND VALIDATION OF DERIVATIVE SPECTROPHOTOMETRIC METHOD FOR
DEVELOPMENT AND VALIDATION OF DERIVATIVE SPECTROPHOTOMETRIC METHOD FOR

... Atorvastatin calcium (AT) is hypolipidemic agent and Amlodipine besylate (AM) is calcium channel blocker. The combination of both drugs is used in treatment of hypertension. The present communication deals with development of simple, sensitive, rapid and economical method for simultaneous estimation ...
Enhancement of Dissolution rate of Rifabutin by preparation of
Enhancement of Dissolution rate of Rifabutin by preparation of

... by hydrophobicity, i.e., inability to form hydrogen bonds with water and/ or by high lattice energy. One market analysis report estimated that worldwide sales of about $37 billion of drugs were insoluble or poorly soluble.4 The conversion of an aqueous insoluble drug to a salt form, pH adjustment an ...
Economic and Microbiologic Evaluation of Single
Economic and Microbiologic Evaluation of Single

... The future of health care is a topic of ongoing debate in the US government. Because medication costs constitute a large portion of the budgets of health care organizations, and with continued development of new molecular entities, there is a need for all institutions to evaluate operations to ident ...
International Journal of Phytopharmacology
International Journal of Phytopharmacology

... be excluded from other site. The fact that absorption rate of drug into the body can be decreased by reduction of the rate of release of the drug from the dosage form is one of the most recent and interesting result of pharmaceutical research. Once a day or at the most twice a day formulation is a h ...
the side effects of common psychiatric drugs
the side effects of common psychiatric drugs

... the same warnings as Ritalin and potential for abuse. Metadate should not be taken if: “You have significant anxiety, tension, or agitation since METADATE CD may make these conditions worse…you have glaucoma, an eye disease, you have tics or Tourette’s Syndrome (condition manifesting in involuntary ...
View press release  doc - 79 KB
View press release doc - 79 KB

... Prof. Sornchai Looareesuwan, Department of Tropical Medicine, Mahidol University, Bangkok Thailand, said, “The success, so far, of RBx 11160 in its clinical trials is very encouraging to researchers. We believe this drug may turn out to be one of the most significant advances in malaria treatment i ...
The H2 Blockers` Rx-to OTC Switch: For Whom Will It Spell Relief
The H2 Blockers` Rx-to OTC Switch: For Whom Will It Spell Relief

... Application (NDA) procedures; or (iii) is not safe for use without a physician’s supervision. The last category, which generally adopted the FDA’s regulation that prescription-only drugs are those that can be adequately labeled for proper use by a lay person, is the one that presents the heart of th ...
Assignments of PGDPSM – July 2015 Batch
Assignments of PGDPSM – July 2015 Batch

... Leave 4 cm margin on the left, top and bottom of your answer sheet. Your answers should be precise, handwritten. They should not be copied from the text material as it is and rather should be written in your own language. Answers in the form of photocopy or scanned from any source will not be accept ...
The Physiological Basis Of Drug Addiction
The Physiological Basis Of Drug Addiction

... independent of HPA axis activation. Other environmental factors other than drug exposure such as age, stress and exercise, can also have an effect of neurogenesis by regulating the hypothalamic-pituitaryadrenal (HPA) axis. Mounting evidence suggests this for 3 reasons: small doses of opiates and psy ...
The Reta Trust Pharmacy Schedule of Benefits for 3
The Reta Trust Pharmacy Schedule of Benefits for 3

... Medication for which the cost is recoverable under any workers’ compensation or occupational disease law or any state or government agency, or medication furnished by any other drug or medical service for which no charge is made to the patient. Medication prescribed for Experimental or Investigatio ...
ISOA/ARF Drug Development Tutorial
ISOA/ARF Drug Development Tutorial

... concept in vivo; together this defines its clinical potential. Validation involves studies in intact animals or disease-related cell-based models that can provide information about the integrative response of an organism to a pharmacological intervention and thereby help to predict the possible prof ...
MECHANISM OF SOLUBILITY OF LIQUISOLID FORMULATION IN NON VOLATILE SOLVENT:
MECHANISM OF SOLUBILITY OF LIQUISOLID FORMULATION IN NON VOLATILE SOLVENT:

... 400, glycerin and polysorbate 80 were carried out. Results shows that Prednisolone has more solubility in propylene glycol when compared to other liquid vehicle. The dissolution study of liquisolid tablets prepared with propylene glycol as liquid vehicle showed a significantly higher release rates t ...
Dev. Date
Dev. Date

... The removal of drug from the body Drug metabolising enzymes that are embedded in the smooth endoplasmic reticulum of liver cells Charged or polar in nature (not lipid soluble) A loop diuretic which is polar in nature and cleared almost exclusively by the kidneys A cardioselective beta adrenoreceptor ...
Polyesters and polyester carbonates for controlled drug delivery
Polyesters and polyester carbonates for controlled drug delivery

... tage. Injectable drug delivery systems include microspheres, nanospheres, polymeric micelles, polymerosomes and conjugates. Examples of commercially available microspheres obtained from aliphatic polyesters are presented in Table 1 [5, 6, 12—15]. Compared to injectable drug delivery systems, pharmac ...
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Orphan drug

An orphan drug is a pharmaceutical agent that has been developed specifically to treat a rare medical condition, the condition itself being referred to as an orphan disease.In the US and EU it is easier to gain marketing approval for an orphan drug, and there may be other financial incentives, such as extended exclusivity periods, all intended to encourage the development of drugs which might otherwise lack a sufficient profit motive. The assignment of orphan status to a disease and to any drugs developed to treat it is a matter of public policy in many countries, and has resulted in medical breakthroughs that may not have otherwise been achieved due to the economics of drug research and development.According to Thomson Reuters in their 2012 publication ""The Economic Power of Orphan Drugs"", there has been increased investing in orphan drug Research and Development partly due to the U. S. Orphan Drug Act (ODA) 1983 and similar Acts in other regions of the world and also driven by ""high-profile philanthropic funding."" The period between 2001 to 2011 was the ""most productive period in the history of orphan drug development, in terms of average annual orphan drug designations and orphan drug approvals."" For the same decade the compound annual growth rate (CAGR) of the orphan drugs was an ""impressive 25.8 percent, compared to only 20.1 percent for a matched control group of non-orphan drugs."" By 2012 the market for orphan drugs was worth USD$637 million compared to the USD$638 million matched control group of non-orphan drugs, Thomson Reuters.By 2012, ""the revenue-generating potential of orphan drugs [was] as great as for non-orphan drugs, even though patient populations for rare diseases are significantly smaller. Moreover, we suggest that orphan drugs have greater profitability when considered in the full context of developmental drivers including government financial incentives, smaller clinical trial sizes, shorter clinical trial times and higher rates of regulatory success.""
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