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Heparin, low-molecular–weight heparins, and heparin - hem
Heparin, low-molecular–weight heparins, and heparin - hem

... thrombotic stroke; however, it is now used widely for various cardiovascular and peripheral vascular indications. This drug has gradually replaced the original ADP antagonist, ticlopidine, because of the side effects associated with ticlopidine. Plavix is widely used by cardiologists for interventio ...
Pharmacy Law Review 2010
Pharmacy Law Review 2010

... Its is unlawful to introduce into interstate commerce and article that is ...
Medical Emergencies in the Dental Surgery
Medical Emergencies in the Dental Surgery

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Study Guide for Veterinary Drug Dispenser Licence
Study Guide for Veterinary Drug Dispenser Licence

... (vaccines and bacterins) should be handled, stored and used. Pharmaceuticals have brought enormous benefits to mankind. Some of the most deadly diseases such as Small Pox have been eradicated while others have been effectively controlled through vaccines. The same benefits have been achieved through ...
DrugFacts MDMA 2013
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... pamine,  and  norepinephrine.  The  emo-­‐ tional  and  pro-­‐social  effects  of  MDMA   are  likely  caused  directly  or  indirectly  by   the  release  of  large  amounts  of  seroto-­‐ nin,  which  influences  mood  (as  well  as   oth ...
Antithyroid Drugs
Antithyroid Drugs

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DEVELOPMENT, CHARACTERIZATION AND EVALUATION OF SOLID DISPERSIONS OF
DEVELOPMENT, CHARACTERIZATION AND EVALUATION OF SOLID DISPERSIONS OF

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Aging Biology and Geriatric Clinical Pharmacology
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Drugged Driving Expert Panel Report
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NSW TAG Off-Label Use of Registered Drugs and Drugs

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Antithyroid Drugs
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... so that only those patients most likely to have a remission would be subjected to the potential risks and inconvenience of antithyroid-drug therapy. In addition, there have been attempts to develop more effective strategies for the use of antithyroid drugs to enhance the chances of remission, includ ...
Formulation
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Large-Scale Elucidation of Drug Response Pathways in Humans
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... Stevens-Johnson syndrome, a potentially deadly skin disease that usually results from adverse drug reaction. Tenoxicam and Nimesulide were indeed reported to (rarely) produce such a side effect, as are many other NSAIDs (Mockenhaupt et al., 2007; Roujeau et al., 1995). Nimesulide is also predicted t ...
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... clostridium botulinum toxin 17, horse radish peroxidase l8 , albumin 19 and eiastase20 has been reported. However, the extent of macromolecular absorption is very limited, and is restricted by the barrier function of the intestine. The improvement of intestinal absorption of macromolecules could be ...
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... in children. This is not a large, lucrative market and the management of the company made the calculated decision to bypass the FDA’s drug approval process. It marketed Neurontin through medical education programs to physicians, questionable research reports, and medical journal publication, indicat ...
formulation and evaluation of bilayer tablet of
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Strict Liability in the Manufacture of
Strict Liability in the Manufacture of

... manufactured products. 11 One reason for this different treatment is the interaction which occurs between the body of the patient and the drug's chemical compound. When a drug is ingested, the response of an individual patient is difficult to predict. Every effect and each adverse reaction is unique ...
Shan Chikhale, Professor of Pharmaceutical Sciences, School of
Shan Chikhale, Professor of Pharmaceutical Sciences, School of

...  Pharmacists are the only health care professionals that possess the knowledge and skill required for compounding and preparing medications to meet the unique needs of individual patients.  Hence, need for compounding pharmacies and for this industry is growing.  Safe, effective, and high-quality ...
Metabolic Fate of Pharmaceuticals: A Focus on Slow Metabolizers
Metabolic Fate of Pharmaceuticals: A Focus on Slow Metabolizers

... received considerable attention. Drug metabolism is affected by numerous factors of both environmental and genetic origin. Recently, increased attention has been given to the gene tic factors that may affect drug metabolism. A substantial portion of the population may have altered drug metabolism du ...
Disparate practical way of doing solubility enhancement study to
Disparate practical way of doing solubility enhancement study to

... information that can influence a risk assessment. In soil, a contaminant bioavailability can be measured in several ways such as: i. Extraction using acids and bases ii. Extraction using biological fluids iii. In vitro assays using bacterial systems iv. In vivo assays using aquatic mammals and organ ...
MS_Word ~ 357 KB - CIAP
MS_Word ~ 357 KB - CIAP

... making the drug available would be recovered by potential sales 3. ...
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Orphan drug

An orphan drug is a pharmaceutical agent that has been developed specifically to treat a rare medical condition, the condition itself being referred to as an orphan disease.In the US and EU it is easier to gain marketing approval for an orphan drug, and there may be other financial incentives, such as extended exclusivity periods, all intended to encourage the development of drugs which might otherwise lack a sufficient profit motive. The assignment of orphan status to a disease and to any drugs developed to treat it is a matter of public policy in many countries, and has resulted in medical breakthroughs that may not have otherwise been achieved due to the economics of drug research and development.According to Thomson Reuters in their 2012 publication ""The Economic Power of Orphan Drugs"", there has been increased investing in orphan drug Research and Development partly due to the U. S. Orphan Drug Act (ODA) 1983 and similar Acts in other regions of the world and also driven by ""high-profile philanthropic funding."" The period between 2001 to 2011 was the ""most productive period in the history of orphan drug development, in terms of average annual orphan drug designations and orphan drug approvals."" For the same decade the compound annual growth rate (CAGR) of the orphan drugs was an ""impressive 25.8 percent, compared to only 20.1 percent for a matched control group of non-orphan drugs."" By 2012 the market for orphan drugs was worth USD$637 million compared to the USD$638 million matched control group of non-orphan drugs, Thomson Reuters.By 2012, ""the revenue-generating potential of orphan drugs [was] as great as for non-orphan drugs, even though patient populations for rare diseases are significantly smaller. Moreover, we suggest that orphan drugs have greater profitability when considered in the full context of developmental drivers including government financial incentives, smaller clinical trial sizes, shorter clinical trial times and higher rates of regulatory success.""
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