• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
FORMULATION AND EVALUATION OF PULSATILE DRUG DELIVERY SYSTEM OF
FORMULATION AND EVALUATION OF PULSATILE DRUG DELIVERY SYSTEM OF

... The objective of the present study was to design and evaluate time and pH dependent multiparticulate pulsatile delivery systems of Aceclofenac. Four batches of microspheres namely A1, A2, A3 and A4 were prepared using combination of Eudragit L-100 and S-100 with core: coat ratio 1:0.5, 1:1, 1:1.5 an ...
a review of the medicinal evidence for its therapeutic properties
a review of the medicinal evidence for its therapeutic properties

... term "guggul" is "one that protects against diseases." This attests to the wide respect and therapeutic Ayurvedic applications for this botanical, considered the most important for the removal of "ama," toxic substances which accumulate as a result of sluggish digestion and circulation associated wi ...
Exhibit B
Exhibit B

... FDA disagrees with Novartis' conclusions. By their very nature, bioequivalence studies are designed to determine if the same doses of two different products provide the same plasma concentrations of the active ingredient over time .' While data on symptoms were also collected, the trial was not desi ...
119 Drug Dose Adjustment in Chronic Renal Diseases
119 Drug Dose Adjustment in Chronic Renal Diseases

... drugs decrease renal blood flow and the rate of glomerular filtration in patients with CHF, hepatic cirrhosis with ascites, or CRF or in those who are hypovolemic for any reason. ARF may be precipitated under these circumstances. In all of these settings renal perfusion is more dependent upon prosta ...
Statins - Consumer Health Choices
Statins - Consumer Health Choices

... breakdown in the muscle tissue. ...
Pharmacy Law Review 2010
Pharmacy Law Review 2010

... Its is unlawful to introduce into interstate commerce and article that is ...
Pharmacotherapeutic action of Dasanga Guggulu
Pharmacotherapeutic action of Dasanga Guggulu

... century. It is defined as elevated concentrations of any or all the lipids in the plasma, including hypertriglyceridemia, hypercholesterolemia, etc1. Less physical activities, sedentary life style and mental stress are negatively influenced on increasing serum lipids level. Due to modernization of t ...
Role of US Military Research Programs in the Development of US
Role of US Military Research Programs in the Development of US

... problem in veterans returning from the Korean War. Compliance with chloroquine prophylaxis was good, so malaria symptoms developed only after troops departed from Korea. Dr. Alf Alving (University of Chicago) led a research team under contract to the US Army that evaluated the safety and efficacy of ...
direct-to-consumer advertising
direct-to-consumer advertising

... information presented provides equal emphasis on benefits and risk, and there is no significant risk of information, “fair balance” is assumed to exist (Davis, 1999). The FDA permits three types of DTC prescription drug advertisements: 1) product claim advertisements, which include both the product ...
transcutaneous drug delivery system: a comprehensive review
transcutaneous drug delivery system: a comprehensive review

... matrix bandage formulations for typical delivery of antibiotics have been known since at least as far back as the 1950s, it is about 25 ...
FDA Takes Actions on Pain Medications Containing Propoxyphene
FDA Takes Actions on Pain Medications Containing Propoxyphene

... There are differences in how FDA and those who support the market withdrawal of propoxyphene view the benefit and safety data of this drug. FDA finds there is evidence that propoxyphene can effectively treat pain at recommended doses. FDA also finds that the differences in use patterns between Europ ...
Pharmaceuticals and the Elderly - WHO archives
Pharmaceuticals and the Elderly - WHO archives

... Current "Pipeline" of Products ......................................................................................................... 17 Opportunities for Research into New Pharmaceutical Interventions ......................................... 17 Conclusion ....................................... ...
Placental structure, function and drug transfer
Placental structure, function and drug transfer

... Active transport utilizes energy, usually in the form of ATP, to transport substances against a concentration or electrochemical gradient. Transport is carrier-mediated and saturable and there is competition between related molecules. Active drug transporters are located on both the maternal and fet ...
In Vitro-In Vivo Correlation (IVIVC) and Determining
In Vitro-In Vivo Correlation (IVIVC) and Determining

... administered to humans, in particular through the oral route. It is difficult, if not impossible, to routinely administer accu2010 Bentham Open ...
Ranibizumab or bevacizumab in AMD?
Ranibizumab or bevacizumab in AMD?

... rivista.informazionisuifarmaci.it/avastin-contro-lucentis-ovvero-limpatto-clinico-della-sostenibilita-delle-terapie) The use of Avastin® (bevacizumab, Roche) and Lucentis® (rani­ bizumab, Novartis) in age-related macular degeneration (AMD) has been widely debated and such discussion has reverberated ...
P-glycoprotein and chiral antidepressant drugs: Louise Karlsson Pharmacokinetic, pharmacogenetic and toxicological aspects
P-glycoprotein and chiral antidepressant drugs: Louise Karlsson Pharmacokinetic, pharmacogenetic and toxicological aspects

... now available as a separate SSRI (escitalopram, EsCIT). VEN and CIT are also among the most commonly found drugs in forensic autopsy cases. Few previous studies have examined a possible enantioselective activity of P-gp. Thus, the general aim of this thesis was to study the enantiomeric distribution ...
Properties of Ingredients in Dasanga Guggulu
Properties of Ingredients in Dasanga Guggulu

... century. It is defined as elevated concentrations of any or all the lipids in the plasma, including hypertriglyceridemia, hypercholesterolemia, etc1.Less physical activities, sedentary life style and mental stress are negatively influenced on increasing serum lipids level. Due to modernization of th ...
PDF full-Text - Journal of Investigational Allergology and Clinical
PDF full-Text - Journal of Investigational Allergology and Clinical

... concrete case of CYP3A4 and CYP2D6 [7,8], a number of studies show their expression to be influenced by environmental factors, as a result of which their activity shows great interindividual variability. In the case of the H1 antihistamines, and more specifically of terfenadine and loratadine, great ...
B.Pharm-Syllabus
B.Pharm-Syllabus

... UNIT –III Gases and Vapours : Oxygen, Anaesthetics and Respiratory stimulants. ...
Drug-scavenging Liposomes Attenuate the
Drug-scavenging Liposomes Attenuate the

... extensive hepatic metabolism, their major metabolites retain some activity. However, the first-pass hepatic enzymes are rapidly saturated in intoxicated patients, increasing the bioavailability of the more potent parent drugs. Hallmarks of overdose include bradycardia and hypotension for all CCB poi ...
The anti-tubercular drug delamanid as a potential oral treatment for
The anti-tubercular drug delamanid as a potential oral treatment for

... leishmaniasis, a parasitic infectious disease that causes an estimated 40,000 deaths a year, predominantly in South America, East Africa and the Indian subcontinent. The parasite that causes visceral leishmaniasis is transmitted between individuals by blood-sucking sandflies, and there are currently ...
Generics and public health - WHO archives
Generics and public health - WHO archives

... What are the potential benefits of generics? Better access to needed medicines. Well chosen generics make government or household spend less without loss of quality or safety ...
UV- Vis absorption spectroscopy and colorimetric
UV- Vis absorption spectroscopy and colorimetric

... spectroscopy etc are available for the determination of aspirin content in drugs but these methods are expensive and laborious in nature. Therefore, these methods are neither suitable nor accessible for undergraduate students. In this background, we have used a very simple analytical technique to te ...
Effect of Dextromethorphan, Diphenhydramine, and
Effect of Dextromethorphan, Diphenhydramine, and

... own sleep and functioning during the subsequent day.” [Interesting, drug the child for the benefit of the parent.] Consumers spend billions of dollars per year on OTC medications for cough. “The desire to give or take a medicine commonly outweighs the paucity of sound research on the effect of these ...
Heparin, low-molecular–weight heparins, and heparin - hem
Heparin, low-molecular–weight heparins, and heparin - hem

... thrombotic stroke; however, it is now used widely for various cardiovascular and peripheral vascular indications. This drug has gradually replaced the original ADP antagonist, ticlopidine, because of the side effects associated with ticlopidine. Plavix is widely used by cardiologists for interventio ...
< 1 ... 17 18 19 20 21 22 23 24 25 ... 161 >

Orphan drug

An orphan drug is a pharmaceutical agent that has been developed specifically to treat a rare medical condition, the condition itself being referred to as an orphan disease.In the US and EU it is easier to gain marketing approval for an orphan drug, and there may be other financial incentives, such as extended exclusivity periods, all intended to encourage the development of drugs which might otherwise lack a sufficient profit motive. The assignment of orphan status to a disease and to any drugs developed to treat it is a matter of public policy in many countries, and has resulted in medical breakthroughs that may not have otherwise been achieved due to the economics of drug research and development.According to Thomson Reuters in their 2012 publication ""The Economic Power of Orphan Drugs"", there has been increased investing in orphan drug Research and Development partly due to the U. S. Orphan Drug Act (ODA) 1983 and similar Acts in other regions of the world and also driven by ""high-profile philanthropic funding."" The period between 2001 to 2011 was the ""most productive period in the history of orphan drug development, in terms of average annual orphan drug designations and orphan drug approvals."" For the same decade the compound annual growth rate (CAGR) of the orphan drugs was an ""impressive 25.8 percent, compared to only 20.1 percent for a matched control group of non-orphan drugs."" By 2012 the market for orphan drugs was worth USD$637 million compared to the USD$638 million matched control group of non-orphan drugs, Thomson Reuters.By 2012, ""the revenue-generating potential of orphan drugs [was] as great as for non-orphan drugs, even though patient populations for rare diseases are significantly smaller. Moreover, we suggest that orphan drugs have greater profitability when considered in the full context of developmental drivers including government financial incentives, smaller clinical trial sizes, shorter clinical trial times and higher rates of regulatory success.""
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report