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11-15-04 Anti-infective Agents short form
11-15-04 Anti-infective Agents short form

... Fungicidal: Capable of killing fungi Drugs bind to fungal membranes and increase permeability, nutrients leak out, and fungi die Drugs: amphotericin B, ketaconazole, miconazole, nystatin Fungistatic: Limits the growth of active fungi but does not eradicate the microorganisms Drug binds to keratin in ...
The current state of rare diseases in Mexico
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幻灯片 1
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Pharmaceuticals and OTC*s
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India`s Marketing Regulations of Drugs
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... distribution (Vd) can be calculated from the total amount of drug administered and the concentration of the drug in the blood which can be measured c. It is only a true “volume” if the “concentration” of the drug is the same in all compartments/tissues. Drug binding and accumulation of drugs in fat ...
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... consumption of „ethnobotanicals" was agitation. The treatment used was mainly symptomatic and supportives, with sedatives, anxiolytics, antipsyhotics, as well as infusions for the management of the electrolyte imbalance and rehydration. The rapid urine drug screen tests were applied for the analytic ...
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... PA – This drug requires prior authorization. ST – Requires other selected drugs to be tried first. QL – This drug has quantity limits on amount covered. SPRx – Specialty drug; many plans require you to get this type of drug from a Preferred Specialty Pharmacy. ...
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... additional cases of PML in people who were not taking another immunomodulating or immunosuppressing medication at the same time have been reported in the post-marketing phase. The absolute risk for PML in patients treated with Tysabri® cannot be precisely estimated. However, the drug’s sponsor has r ...
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Orphan drug

An orphan drug is a pharmaceutical agent that has been developed specifically to treat a rare medical condition, the condition itself being referred to as an orphan disease.In the US and EU it is easier to gain marketing approval for an orphan drug, and there may be other financial incentives, such as extended exclusivity periods, all intended to encourage the development of drugs which might otherwise lack a sufficient profit motive. The assignment of orphan status to a disease and to any drugs developed to treat it is a matter of public policy in many countries, and has resulted in medical breakthroughs that may not have otherwise been achieved due to the economics of drug research and development.According to Thomson Reuters in their 2012 publication ""The Economic Power of Orphan Drugs"", there has been increased investing in orphan drug Research and Development partly due to the U. S. Orphan Drug Act (ODA) 1983 and similar Acts in other regions of the world and also driven by ""high-profile philanthropic funding."" The period between 2001 to 2011 was the ""most productive period in the history of orphan drug development, in terms of average annual orphan drug designations and orphan drug approvals."" For the same decade the compound annual growth rate (CAGR) of the orphan drugs was an ""impressive 25.8 percent, compared to only 20.1 percent for a matched control group of non-orphan drugs."" By 2012 the market for orphan drugs was worth USD$637 million compared to the USD$638 million matched control group of non-orphan drugs, Thomson Reuters.By 2012, ""the revenue-generating potential of orphan drugs [was] as great as for non-orphan drugs, even though patient populations for rare diseases are significantly smaller. Moreover, we suggest that orphan drugs have greater profitability when considered in the full context of developmental drivers including government financial incentives, smaller clinical trial sizes, shorter clinical trial times and higher rates of regulatory success.""
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