• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Session 7 - Teaching Slides
Session 7 - Teaching Slides

... Name the 4 components of pharmacokinetics. Describe the importance of the liver’s P450 system in drug metabolism. Name one P450 drug inducer and two P450 drug inhibitors. Describe the affect Rifampin has on NVP and EFV blood levels. Describe the affect Rifampin has on Protease Inhibitor (PI) blood l ...
April, Number 4 - UF Health Professionals
April, Number 4 - UF Health Professionals

... The implications of drug shortages are numerous. The obvious major impact is decreased access to lifesaving drugs. In addition, the cost of those lifesaving drugs may increase as a result. For example, the cost of cancer care has escalated as generic products are in short supply and hospitals ar ...
NEW Psychoactive DRUGS www.mycrew.org.uk
NEW Psychoactive DRUGS www.mycrew.org.uk

... developing new drugs with similar effects to illegal ones. These products are not covered by existing legislation and vendors are able to avoid existing laws by labelling these drugs with terms such as ‘not for human consumption’. However this can cause greater harm as it prevents the shop employees ...
MemberHealth - SilverScript
MemberHealth - SilverScript

... Staying healthy for less One way to save on prescription drug costs is to switch from a brand name drug to a generic drug used to treat the same condition. Generics are safe and effective because the Food and Drug Administration (FDA) requires that they have the same ...
Investing in Biotech - Cy Lynch
Investing in Biotech - Cy Lynch

... The information in this presentation is for educational purposes only and is not intended to be a recommendation to purchase or sell any of the stocks, mutual funds, or other securities that may be referenced. The securities of companies referenced or featured in the seminar materials are for illust ...
Anti-HIV Medications + Street Drugs
Anti-HIV Medications + Street Drugs

... • For most drugs to be effective and not kill you, they need to be metabolized [broken down] by the liver or kidneys. These organs have limited resources and a set number of chemicals which accomplish this task. Because of this, certain drugs, whether they're HIV medications or recreational drugs, c ...
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

...  Protection of prescription pads • store unused prescription pads in a safe place • minimize the number of pads in use at one time • have prescription blanks numbered consecutively so that missing sheets would be detected • never sign prescription blanks in advance • Write out the actual quantity i ...
Pharmacology MCQs
Pharmacology MCQs

... a. usually does not cross the blood-brain barrier. b. inhibits cholinesterase reversibly. c. is erratically absorbed after oral administration. d. can be used in the symptomatic treatment of myasthenia gravis. 48. Propranolol is used the treatment of: a. hypertension. b. asthma. c. angina pectoris. ...
Sedative-HypnoticsJGeneral Depressants alcohol (ethyl alcohol, or
Sedative-HypnoticsJGeneral Depressants alcohol (ethyl alcohol, or

... administering cocaine and amphetamines is extremely reinforcing; they possess what pharmacologists call "immediate sensual appeal." Taking them generates the impulse to take them regularly, regardless of the obstacles, pain, or cost. In popular or lay terms, they are pleasurable. It should come as n ...
Zero order kinetics
Zero order kinetics

... to cross lipid-rich cell membranes. Paradoxically, drugs that are extremely lipophilic are also poorly absorbed, because they are totally insoluble in aqueous body fluids and, therefore, cannot gain access to the surface of cells. For a drug to be readily absorbed, it must be largely lipophilic, yet ...
Antiamoebic Drugs
Antiamoebic Drugs

... Antiamoebic Drugs • (one strategy for treating luminal amebiasis is to add antibiotics, such as tetracyclines to the treatment regimen, resulting in a reduction in intestinal flora – the amoeba’s major food source). • The trophozoites within the intestine are slowly carried toward the rectum, where ...
Phase I Issues for Novel TB Drugs
Phase I Issues for Novel TB Drugs

... December 6-7, 2005 ...
drugs
drugs

... these drugs. Act requires an individual to have a special DEA registration number in order to possess controlled substances. ...
Polypharmacy Powerpoint Presentation
Polypharmacy Powerpoint Presentation

... • Those 65 year and older represent 12.6% of the US population, approximately one in eight Americans. • The elderly account for nearly 30% of the nation’s health care expenditures and 25% of drug expenditures. • A survey of non-institutionalized participants found that 12% of women aged above 65 yea ...
Major Drug Conventions
Major Drug Conventions

... penetrate, contaminate and corrupt the structures of Government , legitimate commercial and financial business and society at all its levels. • Eradication of illicit traffic is the collective responsibility of all the states and the coordinated action within the framework of International cooperati ...
Slide 1
Slide 1

... it has not been possible to obtain complete information on this medicinal product. The European Medicines Agency (EMEA) wil ...
GENERAL PRINCIPLES OF CLINICAL PHARMACOLOGY
GENERAL PRINCIPLES OF CLINICAL PHARMACOLOGY

... beads within capsules. Some of the more common prefixes or suffixes for sustained-release, controlled-release, controlled-delivery, extended-release, prolonged-release, slow-release products include: 12-hour, 24-hour, CC, CD, CR, ER, LA, Retard, SA, Slo-, SR, XL, XR, or XT.  Enteric-coated tablets, ...
GREEN METHODS TO DELIVER AMINOGLYCOSIDE DRUGS
GREEN METHODS TO DELIVER AMINOGLYCOSIDE DRUGS

... Figure 1. Common structures of aminoglycoside families Green chemistry in pharmaceutical development often concern the synthesis of the active ingredient, but green-chemistry techniques also can be applied to drug-product manufacturing, formulation development, and drug delivery.5 Drugs with the abi ...
Ana Santos Rutschman
Ana Santos Rutschman

... Italy ...
However, the frequency of these four genotypes varies depending
However, the frequency of these four genotypes varies depending

... • Any clinically significant change in the patient’s status due to a DDI makes that DDI clinically significant ...
Kinetoplastida: new therapeutic strategies
Kinetoplastida: new therapeutic strategies

... responses in infected tissues producing the characteristic lesions of chronic Chagas disease (Tarleton et al., 2001). Significant reduction of T. cruzi from infected patients appears, therefore, to be essential to prevent disease progression and to avert its irreversible longterm consequences. Studi ...
6GuN8Qo9Dfp1QZDN8ubBtuHr_F8SNcwjgzjV3UndOuNh4gNcd
6GuN8Qo9Dfp1QZDN8ubBtuHr_F8SNcwjgzjV3UndOuNh4gNcd

... 79.Thrombocytopenia is an abnormal increase in the number of platelets in the blood; patients with Thrombocytopenia are susceptible to hemorrhage. 80.Neutropenia is an abnormal increase in the number of neutrophils in the blood. 81.Pernicious anemia is a form of megaloplastic anemia that results fro ...
Course Syllabus
Course Syllabus

... Pharmacology is the study of drugs. The course will cover the important concepts students need to know about the basis of drug action and the pharmacological basis of therapeutics. The first part of the course will deal with general principles of pharmacology, including pharmacodynamics, and pharmac ...
Basic Principles of Pharmacology
Basic Principles of Pharmacology

... 1. first-order (exponential) kinetics All pharmacokinetic processes (abs., distr., met. excr.) occur at a rate directly proportional to conc. of drug e.g. increasing dose increases these processes 2. zero-order (saturation) kinetics Apply mainly to met. And elimination where their rates reach satura ...
pharmacokinetics-4
pharmacokinetics-4

... Cell Membranes: This barrier is permeable to many drug molecules but not to others, depending on their lipid solubility. Small pores, 8 angstroms, permit small molecules such as alcohol and water to pass through. Walls of Capillaries: Pores between the cells are larger than most drug molecules, allo ...
< 1 ... 109 110 111 112 113 114 115 116 117 ... 161 >

Orphan drug

An orphan drug is a pharmaceutical agent that has been developed specifically to treat a rare medical condition, the condition itself being referred to as an orphan disease.In the US and EU it is easier to gain marketing approval for an orphan drug, and there may be other financial incentives, such as extended exclusivity periods, all intended to encourage the development of drugs which might otherwise lack a sufficient profit motive. The assignment of orphan status to a disease and to any drugs developed to treat it is a matter of public policy in many countries, and has resulted in medical breakthroughs that may not have otherwise been achieved due to the economics of drug research and development.According to Thomson Reuters in their 2012 publication ""The Economic Power of Orphan Drugs"", there has been increased investing in orphan drug Research and Development partly due to the U. S. Orphan Drug Act (ODA) 1983 and similar Acts in other regions of the world and also driven by ""high-profile philanthropic funding."" The period between 2001 to 2011 was the ""most productive period in the history of orphan drug development, in terms of average annual orphan drug designations and orphan drug approvals."" For the same decade the compound annual growth rate (CAGR) of the orphan drugs was an ""impressive 25.8 percent, compared to only 20.1 percent for a matched control group of non-orphan drugs."" By 2012 the market for orphan drugs was worth USD$637 million compared to the USD$638 million matched control group of non-orphan drugs, Thomson Reuters.By 2012, ""the revenue-generating potential of orphan drugs [was] as great as for non-orphan drugs, even though patient populations for rare diseases are significantly smaller. Moreover, we suggest that orphan drugs have greater profitability when considered in the full context of developmental drivers including government financial incentives, smaller clinical trial sizes, shorter clinical trial times and higher rates of regulatory success.""
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report