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Preview Sample 1
Preview Sample 1

... Mosby items and derived items © 2011, 2007, 2004 by Mosby, Inc., an affiliate of Elsevier Inc. ...
Absorption - INAYA Medical College
Absorption - INAYA Medical College

... Disadvantages of the Oral Route: ...
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kinetics.
kinetics.

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Metabolism of drugs
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Final Internal Assessment: PHARMACOLOGY
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on methodological conference
on methodological conference

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MixJect - West Pharmaceutical Services
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DEVELOPMENT AND IMPLEMENTATION OF PEDIATRIC FORMULARY & DRUG THERAPY
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No Slide Title
No Slide Title

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... that drugs are being prescribed and given to the patients at the wrong time. Pharmacists may notice that doctors are giving high doses of Tylenol to patients with a bad liver, which can cause liver failure. Patients are also over-prescribed by doctors. A pharmacist may notice that they are on drugs ...
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... environment, like the water supply. Although these are trace amounts, there is increasing concern about this trend. For example, the theoretical effect of disposed antibiotics on microbial resistance is a concern. Of course, the entire course of an antibiotic should be taken, and there should rarely ...
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pharmacology review

... molecules metabolized in liver; also reduces protein binding; causes reduction in metabolic capacity as hepatic parenchyma damaged; intrahepatic shunting causes molecules to pass through shunts without exposure to enzyme system, resulting in lower metabolism; cardiac failure influences elimination ( ...
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Orphan drug

An orphan drug is a pharmaceutical agent that has been developed specifically to treat a rare medical condition, the condition itself being referred to as an orphan disease.In the US and EU it is easier to gain marketing approval for an orphan drug, and there may be other financial incentives, such as extended exclusivity periods, all intended to encourage the development of drugs which might otherwise lack a sufficient profit motive. The assignment of orphan status to a disease and to any drugs developed to treat it is a matter of public policy in many countries, and has resulted in medical breakthroughs that may not have otherwise been achieved due to the economics of drug research and development.According to Thomson Reuters in their 2012 publication ""The Economic Power of Orphan Drugs"", there has been increased investing in orphan drug Research and Development partly due to the U. S. Orphan Drug Act (ODA) 1983 and similar Acts in other regions of the world and also driven by ""high-profile philanthropic funding."" The period between 2001 to 2011 was the ""most productive period in the history of orphan drug development, in terms of average annual orphan drug designations and orphan drug approvals."" For the same decade the compound annual growth rate (CAGR) of the orphan drugs was an ""impressive 25.8 percent, compared to only 20.1 percent for a matched control group of non-orphan drugs."" By 2012 the market for orphan drugs was worth USD$637 million compared to the USD$638 million matched control group of non-orphan drugs, Thomson Reuters.By 2012, ""the revenue-generating potential of orphan drugs [was] as great as for non-orphan drugs, even though patient populations for rare diseases are significantly smaller. Moreover, we suggest that orphan drugs have greater profitability when considered in the full context of developmental drivers including government financial incentives, smaller clinical trial sizes, shorter clinical trial times and higher rates of regulatory success.""
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