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No Slide Title
No Slide Title

... • Appear 2 to 8 months after birth; maximum concentration by 10 years of age – Antibody-A and/or antibody-B (both or none) are found in plasma • You do not form antibodies against your antigens ...
1/2012 A simple no-wash method for the flow cytometric
1/2012 A simple no-wash method for the flow cytometric

... total leukocyte numbers. However, it is far less easy to reliably and reproducibly determine changes in leukocyte subsets, where staining of cell surface markers is necessary. Traditionally, peripheral blood mononuclear cells (PBMCs) are separated from red blood cells using density-gradient centrifu ...
REGULATION 4213 Universal Precautions
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... infection through contact with blood or body fluids and are based on the premise that all blood and body fluids are a potential source of infection. The bloodborne diseases most commonly transmitted in this manner are Hepatitis B, Hepatitis C and HIV. The viruses for these diseases can be transmitte ...
Type III (Immune-Complex Mediated)
Type III (Immune-Complex Mediated)

... • Results when cells are destroyed by an immune response, often due to the combined activities of complement and antibodies • Is a component of many autoimmune diseases • 2 significant examples • Destruction of blood cells following an incompatible blood transfusion • Destruction of fetal red blood ...
Revision for Transport in Animals
Revision for Transport in Animals

... Blood from RA to LA; blood from LA to LV Ventricles receive impulses from AVN via Purkinje fibres – ventricles contract (bottom upwards) – force of blood causes AV valves to close (lub)– prevents blood flowing back into atria Blood is forced from RV into PA through pulm semilunar valves and from LV ...
Chapter 11
Chapter 11

... – Another important antigen – Becomes critical during pregnancies of Rhnegative women ...
Blood
Blood

... a. Antigens- structures (often glycoproteins) that extend from the exterior of a cell membrane, which can be used for selfidentification; more importantly, they can be recognized as foreign by another organism. So, for example, if a bacterium enters your body, immune cells can recognize it as foreig ...
CHAPTER 47, SECTIONS 1 AND 2 THE CIRCULATORY
CHAPTER 47, SECTIONS 1 AND 2 THE CIRCULATORY

... ______________ BLOOD CELLS (RBC), ________________ BLOOD CELLS (WBC), AND ___________________. RED BLOOD CELLS (RBC) ERTHROCYTES 1. RBC are the most ____________________ of the Blood Cells. One microliter of blood contains approx. 5 million RBCs. 2. RBC are _______________________, or shaped so that ...
nrosci-biosc 1070-2070 - Pitt Honors Human Physiology
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... negatively impact on the ability to form blood clots.  A genetic disorder, hemophilia, also leaves an individual incapable of forming blood clots. Hemophiliacs typically lack Factor VIII. Almost all of the people who suffer from hemophilia are male, as the defective gene is on the X chromosome. It ...
Blood transfusion
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... The science of blood transfusion dates to the first decade of the 19th century, with the discovery of distinct blood types leading to the practice of mixing some blood from the donor and the receiver before the transfusion (an early form of cross-matching). In 1818, Dr. James Blundell, a British obs ...
Association of ABO and Rh blood groups with blood
Association of ABO and Rh blood groups with blood

... Table 2. Distribution of ABO blood group system in subjects withnormal and elevated blood pressure. ...
Humipak Verification Test Summary March 2011 HUMIPAK
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New molecular basis for the Cromer null phenotype
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... mentioned as a limitation of genotyping – BUT this case highlights the ability to detect the presence of two alleles (K and k) in the paternal sample by genotyping and enable the accurate prediction of risk for HDFN ...
The Rh System
The Rh System

...  Patient can make anti-D directed at portion of antigen that is missing. ...
Circulation MCQs
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... The greater the heart muscle is stretched during filling, the greater will be the force of contraction Within reasonable limits – changes in the arterial pressure against which the heart pumps have almost no effect on the cardiac output Contribution of right atrial stretch to increasing amount of bl ...
Tissues in the lungs
Tissues in the lungs

... the tissues drain excess fluid into larger vessels, which eventually feed the fluid back into the blood system in the chest cavity. Lymph fluid is similar to tissue fluid and contains the same solutes. There will be less oxygen and fewer nutrients, as these have been absorbed by the body cells. Ther ...
Ventricular_Tachycardia
Ventricular_Tachycardia

... Ventricular tachycardia occurs when electrical impulses originating either from the ventricles cause rapid ventricular depolarization (140-250 beats per minute). Since the impulse originates from the ventricles, the QRS complexes are wide and bizarre. Ventricular impulses can be sometimes conducted ...
MiniCollect® Z No Additive Tubes - Greiner Bio-One
MiniCollect® Z No Additive Tubes - Greiner Bio-One

... 10 minutes. Centrifugation should be done at a temperature of 15°C-24°C (25°C / 77°F). It is not recommended to re-centrifuge tubes once the barrier has been formed. Other centrifugation settings may also provide acceptable separation. Barriers are more stable when tubes are spun in centrifuges with ...
Standard Precautions
Standard Precautions

... Blood means human blood, human blood components, and products made from human blood.   ...
Blood Cells - Dr Magrann
Blood Cells - Dr Magrann

...  This region is known as the hypervariable region. Each of these variants can bind to a different target, known as an antigen.  This huge diversity of antibodies allows the immune system to recognize an equally wide diversity of antigens.  IMMUNITY: B Cells that have matured into plasma cells whi ...
Objectives/Competencies - Springfield Technical Community College
Objectives/Competencies - Springfield Technical Community College

... 9. Students will identify the types of cells involved in the Processes of Adaptive Immunity. 10. Students will describe the MHC – Major Histocompatibility Complex and its function. ...
Kidd Blood Group System - the UCLA Department of Pathology
Kidd Blood Group System - the UCLA Department of Pathology

...  Jka was discovered in 1951 by Allen: Mrs. Kidd had hemolytic disease of newborn (HDN) in her son. A new RBC alloantibody was detected in her serum, reacted with her husband’s RBCs.  Jkb was found in 1953 by Plaut  The antigens were independent of other known blood groups. They named after Mrs. K ...
Monoclonal and Polyclonal Antibodies
Monoclonal and Polyclonal Antibodies

... First studied as early as 1895, antibodies comprise an integral element of the human immune response to infection. Advances in the field of immunochemistry by such pioneers as Arrhenius, Pauling, and Karl Landsteiner have provided a working model of antibodyantigen binding, while the development of ...
ABO and Rh Blood Typing
ABO and Rh Blood Typing

... Rh Immune globulin - Concentrated solution of Anti-D from human plasma which is given to pregnant women who are Rh negative and who may be carrying and/or have delivered an Rh positive baby. There are several brands available, e.g., RhoGam. Immunoglobulin - Proteins with known immune response activi ...
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Blood type



A blood type (also called a blood group) is a classification of blood based on the presence or absence of inherited antigenic substances on the surface of red blood cells (RBCs). These antigens may be proteins, carbohydrates, glycoproteins, or glycolipids, depending on the blood group system. Some of these antigens are also present on the surface of other types of cells of various tissues. Several of these red blood cell surface antigens can stem from one allele (or an alternative version of a gene) and collectively form a blood group system.Blood types are inherited and represent contributions from both parents. A total of 35 human blood group systems are now recognized by the International Society of Blood Transfusion (ISBT). The two most important ones are ABO and the RhD antigen; they determine someone's blood type (A, B, AB and O, with +, − or Null denoting RhD status).Many pregnant women carry a fetus with a blood type which is different from their own, which is not a problem. What can matter is whether the baby is RhD positive or negative. Mothers who are RhD- and carry a RhD+ baby can form antibodies against fetal RBCs. Sometimes these maternal antibodies are IgG, a small immunoglobulin, which can cross the placenta and cause hemolysis of fetal RBCs, which in turn can lead to hemolytic disease of the newborn called erythroblastosis fetalis, an illness of low fetal blood counts that ranges from mild to severe. Sometimes this is lethal for the fetus; in these cases it is called hydrops fetalis.
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