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CHM 222 Organic Chemistry II
CHM 222 Organic Chemistry II

... After completing CHM 222, Organic Chemistry II, the student will be able to: A. Demonstrate an understanding of the structure, nomenclature, reactions, mechanisms and synthesis of the different classes of carbon compounds. B. Describe the characteristics of the different classes of organic compounds ...
Translation - Fog.ccsf.edu
Translation - Fog.ccsf.edu

... Building blocks of proteins Are added to the C-terminal end of a growing polypeptide chain by the formation of a peptide bond Peptide bonds – between the carboxyl group at the end of growing chain and a free amino group of incoming amino acid Proteins are synthesized from its Nterminus to its C-term ...
Protein Synthesis
Protein Synthesis

... DNA contains the information that a cell needs to carry out all of its functions. In a way, DNA is like the cell’s encyclopedia. Suppose that you go to the library to do research for a science project. You find the information in an encyclopedia. You go to the desk to sign out the book, but the libr ...
Unit 1 Test Biology Chapter 2.3
Unit 1 Test Biology Chapter 2.3

... - Carbon-based molecules have three fundamental structures-straight chains, branched chains, and rings. All three types of molecules are the result of carbon’s ability to form four covalent bonds. ...
Slide 1
Slide 1

Translation
Translation

... mRNA is transported "om the nucleus cytoplasm where it attached with the ribosomes which are the site of protein synthesis. ...
Genes and How they work!
Genes and How they work!

... • Crick 1961 – elucidated the genetic code • Logic used - How many bases (nucleotides) are needed to code for 20 amino acids? • One base can code for 4 amino acids (41) • Two bases can code for 16 amino acids (42) • Three bases can code for 64 amino acids (43) • Therefore a sequence of three bases i ...
Thalassospiramide G, a New γ-Amino-Acid
Thalassospiramide G, a New γ-Amino-Acid

... Agrobacterium [13] and B-90063, a dimeric oxazole pyridone analog from Blastobacter [14], which indicate the biomedical potential of this class of proteobacteria. In addition, an early investigation of the α-proteobacterium Thalassospira sp., strain number CNJ328, resulted in the discovery of unique ...
Amide Uses
Amide Uses

... as a reagent in the Bouveault aldehyde synthesis and in the Vilsmeier-Haack reaction, another useful method of forming aldehydes. It is also a common catalyst used in the synthesis of acyl halides, in particular the synthesis of acyl chlorides from carboxylic acids using oxalyl or thionyl chloride. ...
Chapter 2
Chapter 2

... 3-D structure determined by interactions among side chains. 1. H bonding between amino acids 2. Ionic bonding between side chains 3. Hydrophobic interactions by nonpolar side chains 4. Covalent bonding between cysteins (disulfide bonds) 4° Quaternary – 2 or more polypeptide chains or proteins togeth ...
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Alternative G-19

CHNOPS Lab Constructing a Model of Protein Synthesis Name Date
CHNOPS Lab Constructing a Model of Protein Synthesis Name Date

... In a process called transcription, which takes place in the nucleus of the cell, messenger RNA (mRNA) reads and copies the DNA’s nucleotide sequences in the form of a complementary RNA molecule. Then the mRNA carries this information in the form of a code to the ribosomes, where protein synthesis ta ...
Bioknowlodgy worksheet 2.4
Bioknowlodgy worksheet 2.4

... 2.4.U8 Every individual has a unique proteome. 15. The proteome is unque to every individual. a. Define the term genome. ...
Ch. 3 Molecules of Life – Practice Questions – Answer on a separate
Ch. 3 Molecules of Life – Practice Questions – Answer on a separate

... Saturated- have no C=C double bonds and all C are saturated with H atoms. Monounsaturated- have one C=C double bond, and polyunsaturated has two or more C=C bonds. -Explain the health factors related to cholesterol and fat saturation. Saturated fats and LDL cholesterol lead to clogged arteries. Unsa ...
Chapter 17 From Gene to Protein
Chapter 17 From Gene to Protein

... After picking up specific amino acids, tRNA molecule line up by means of their anticodon triplets at complementary codons on mRNA. The attachment of amino acids to its particular tRNA is an ATP-driven process. Ribosomes coordinate the three stages of translation: initiation, elongation, and ...
transfer RNA
transfer RNA

... To the 3’ end, a poly-tail of about 100 to 300 nucleotides is found, which will help the newly formed mRNA bind to a location on the ribosome. ...
Dehydration Synthesis and Hydrolysis Practice
Dehydration Synthesis and Hydrolysis Practice

... individual  monomers  again  is  called  ____________________________.   3. The  organic  molecules  that  serve  as  a  source  of  energy  for  us  are  commonly  called  _________________.     In  what  organ  of  your  body  would  the ...
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File

... Once the type and order of amino acids in a protein have been translated by the ribosome, the amino acids need to be transported over to the correct location to join together to create a protein. Another type of RNA helps transport a specific amino acid over to a specific mRNA codon at the ribosome. ...
Lipids - Cloudfront.net
Lipids - Cloudfront.net

... The “tail” end is scared of water and is given the name HYDROPHOBIC You will see why this is so important when we talk about ...
amino acids - CRCBiologyY11
amino acids - CRCBiologyY11

... Exists as a single chain (rather than double like DNA). The sugar is ribose instead of deoxyribose in DNA. The bases are Adenine, Guanine, Cytosine and Uracil (instead of Thymine in DNA). There are three kinds of RNA, all of which have very ...
Central Dogma
Central Dogma

identifying carbohydrates
identifying carbohydrates

... Two hydrogens and an oxygen are lost as a water molecule. This is known as a dehydration synthesis or condensation reaction. The biuret reagent has two active components: sodium hydroxide (NaOH) and copper sulfate (CuSO4). The NaOH, a strong base, will denature the proteins, causing them to “uncoil” ...
Core Topic 2: Molecular biology 21 hours Essential idea: Living
Core Topic 2: Molecular biology 21 hours Essential idea: Living

... Nature of science: Looking for patterns, trends and discrepancies—most but not all organisms assemble proteins from the same amino acids. (3.1) Understandings:  Amino acids are linked together by condensation to form polypeptides.  There are 20 different amino acids in polypeptides synthesized on ...
Moorpark College Chemistry 11
Moorpark College Chemistry 11

... is very “little” is a “left- handed” molecule is “levorotatory” (i.e., it rotates a plane of polarized light to the left) has the same absolute configuration about the chiral carbon as the most basic of the amino acids,“L-glycine” has the same absolute configuration about the chiral carbon as “Lglyc ...
Proteins perform most functions in the cell [1].
Proteins perform most functions in the cell [1].

... Get in the habit of writing legibly, neatly, and in a NORMAL, MEDIUM-SIZED FONT. Please SCAN documents properly and upload them to Archie. Avoid taking photographs of or uploading dark, washed out, side ways, or upside down homework. Please use the scanner in the school’s media lab if one is not at ...
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Bottromycin



Bottromycin is a macrocyclic peptide with antibiotic activity. It was first discovered in 1957 as a natural product isolated from Streptomyces bottropensis. It has been shown to inhibit methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) among other Gram-positive bacteria and mycoplasma. Bottromycin is structurally distinct from both vancomycin, a glycopeptide antibiotic, and methicillin, a beta-lactam antibiotic.Bottromycin binds to the A site of the ribosome and blocks the binding of aminoacyl-tRNA, therefore inhibiting bacterial protein synthesis. Although bottromycin exhibits antibacterial activity in vitro, it has not yet been developed as a clinical antibiotic, potentially due to its poor stability in blood plasma. To increase its stability in vivo, some bottromycin derivatives have been explored.The structure of bottromycin contains a macrocyclic amidine as well as a thiazole ring. The absolute stereochemistry at several chiral centers has been determined as of 2009. In 2012, a three-dimensional solution structure of bottromycin was published. The solution structure revealed that several methyl groups are on the same face of the structure.Bottromycin falls within the ribosomally synthesized and post-translationally modified peptide class of natural product.
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