IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008.
... 1999). Although GPR54 shares a modest sequence homology with the known galanin receptors, galanin apparently does not bind specifically to this receptor (Lee et al, 1999). In 2001, three teams of investigators which are Kotani et al, 2001; Muir et al, 2001; Ohtaki et al, 2001, discovered in quick su ...
... 1999). Although GPR54 shares a modest sequence homology with the known galanin receptors, galanin apparently does not bind specifically to this receptor (Lee et al, 1999). In 2001, three teams of investigators which are Kotani et al, 2001; Muir et al, 2001; Ohtaki et al, 2001, discovered in quick su ...
Progress in the Understanding of the Genetic Etiology of Vertebral
... binding ligand on the cell surface was found to be erroneous. Instead, a cis mechanism of interaction with Notch was demonstrated, one that results in inhibition of Notch signaling.30,31 Further DLL3 is predominantly expressed in the Golgi apparatus in contrast to other DSL ligands which are express ...
... binding ligand on the cell surface was found to be erroneous. Instead, a cis mechanism of interaction with Notch was demonstrated, one that results in inhibition of Notch signaling.30,31 Further DLL3 is predominantly expressed in the Golgi apparatus in contrast to other DSL ligands which are express ...
AraC Protein, Regulation of the L-arabinose Operon in Escherichia
... The ara gene system, AraC homologs, and AraC protein have been reviewed previously (Schleif, 1992, 1996, 2000, 2003; Gallegos et al., 1997), but an updating and reevaluation are necessary in the light of recent advances. While this review mentions material covered in earlier reviews, it emphasizes m ...
... The ara gene system, AraC homologs, and AraC protein have been reviewed previously (Schleif, 1992, 1996, 2000, 2003; Gallegos et al., 1997), but an updating and reevaluation are necessary in the light of recent advances. While this review mentions material covered in earlier reviews, it emphasizes m ...
Report Number of Nuclear Divisions in the Drosophila Blastoderm
... divisions, comparable to uninjected X161 embryos (Figure 4B and Table 2). This experiment demonstrates that the reduced division number in X161 embryos requires zygotic gene expression. The expression of many early zygotic genes is controlled by the zinc-finger protein Vfl (also called Zelda) [13]. ...
... divisions, comparable to uninjected X161 embryos (Figure 4B and Table 2). This experiment demonstrates that the reduced division number in X161 embryos requires zygotic gene expression. The expression of many early zygotic genes is controlled by the zinc-finger protein Vfl (also called Zelda) [13]. ...
CHEMICAL SYNTHESIS OF PROTEINS : A TOOL FOR PROTEIN
... An ingenious stratagem useful to understand and modulate the structural and functional features of the proteins refers to the modification of their chemical structure. In this regard, the chemical synthesis of proteins appears a key tool, as it allows the unlimited modification of a polypeptide chai ...
... An ingenious stratagem useful to understand and modulate the structural and functional features of the proteins refers to the modification of their chemical structure. In this regard, the chemical synthesis of proteins appears a key tool, as it allows the unlimited modification of a polypeptide chai ...
Original article MOLECULAR CHARACTERISATION OF LUMPY
... characterisation of lumpy skin disease virus and sheeppox virus based on P32 gene. Bulg. J. Vet. Med. (online first). Lumpy skin disease virus (LSDV) and sheeppox virus (SPV) have a considerable economic impact on the cattle and small ruminant industry. They are listed in group A of contagious disea ...
... characterisation of lumpy skin disease virus and sheeppox virus based on P32 gene. Bulg. J. Vet. Med. (online first). Lumpy skin disease virus (LSDV) and sheeppox virus (SPV) have a considerable economic impact on the cattle and small ruminant industry. They are listed in group A of contagious disea ...
Evaluation of deindividuation – essay plan
... With this in mind, males are therefore more likely to be jealous of imagined or actual sexual infidelity. It is suggested that in order to prevent their mate from being unfaithful, they may adopt mate retention strategies; these can range from direct guarding to violence. Consequently this could hel ...
... With this in mind, males are therefore more likely to be jealous of imagined or actual sexual infidelity. It is suggested that in order to prevent their mate from being unfaithful, they may adopt mate retention strategies; these can range from direct guarding to violence. Consequently this could hel ...
Bacillus cereus
... B. megaterium has often been used in the laboratory, and is used as an industrial organism that is able to produce a variety of proteins and sources of bioremediation. Bacillus megaterium is a good source of industrial proteins because it is both a desirable cloning host and produces a large variat ...
... B. megaterium has often been used in the laboratory, and is used as an industrial organism that is able to produce a variety of proteins and sources of bioremediation. Bacillus megaterium is a good source of industrial proteins because it is both a desirable cloning host and produces a large variat ...
The Plant Cell - Molecular and Cell Biology
... century before the discovery of the structure of DNA, the chemical nature of mutations, the “central dogma (fact) of molecular biology,” the notion that genes code for enzymes (or enzyme subunits) – in essense, before the discovery of anything at all relevant to what is being studied here – Mendel c ...
... century before the discovery of the structure of DNA, the chemical nature of mutations, the “central dogma (fact) of molecular biology,” the notion that genes code for enzymes (or enzyme subunits) – in essense, before the discovery of anything at all relevant to what is being studied here – Mendel c ...
The daily rhythm of mice
... deficient for the nuclear receptor REV-ERBa showed a shorter period probably due to dampened amplitude of Bmal1 expression [41]. The REV-ERBa protein bound to the promoter region of the Bmal1 gene in the phase of transcriptional repression [31]. This specific action of REV-ERBa was exploited to shut d ...
... deficient for the nuclear receptor REV-ERBa showed a shorter period probably due to dampened amplitude of Bmal1 expression [41]. The REV-ERBa protein bound to the promoter region of the Bmal1 gene in the phase of transcriptional repression [31]. This specific action of REV-ERBa was exploited to shut d ...
Statistical potential-based amino acid similarity
... experimentally determined sequences and structures of proteins, applying the knowledge that homologous proteins have a similar fold.4,5 This evolutionary principle is extended to state that protein local fragments of a similar sequence, which do not necessarily have an evolutionary relationship, hav ...
... experimentally determined sequences and structures of proteins, applying the knowledge that homologous proteins have a similar fold.4,5 This evolutionary principle is extended to state that protein local fragments of a similar sequence, which do not necessarily have an evolutionary relationship, hav ...
Quantitative Genetics
... an aunt all started and ran their own companies and say they cannot imagine any other livelihood. Why are so many people in the same clan hooked? Some of them have a theory. They believe that somewhere in their chromosomes lurks an actual entrepreneurial gene -that their bent for business really is ...
... an aunt all started and ran their own companies and say they cannot imagine any other livelihood. Why are so many people in the same clan hooked? Some of them have a theory. They believe that somewhere in their chromosomes lurks an actual entrepreneurial gene -that their bent for business really is ...
Associative Nitrogen-fixation Bacteria and Cyanobacteria.
... The discovery, in Arabidopsis, of two cytochrome P450 enzymes (CYP79B2 and CYT79B3) that catalyze the formation of IAox from Trp, suggests that at least a portion of IAN could be Trp-derived via an IAox intermediate. IAN may also be regarded as a degradation product resulting from the turnover of in ...
... The discovery, in Arabidopsis, of two cytochrome P450 enzymes (CYP79B2 and CYT79B3) that catalyze the formation of IAox from Trp, suggests that at least a portion of IAN could be Trp-derived via an IAox intermediate. IAN may also be regarded as a degradation product resulting from the turnover of in ...
Fibrinogen Bern I: Substitution y 337 Asn + Lys Is
... bands at the same migration distance, corresponding to Lys (AAC + AAA). amino acid substitution y 337 Asn The purified double-stranded PCR-derived fragment was cloned and subjected to sequence analysis. Normal and mutated alleles of fibrinogen Bern I were obtained, showing a G + T transition in the ...
... bands at the same migration distance, corresponding to Lys (AAC + AAA). amino acid substitution y 337 Asn The purified double-stranded PCR-derived fragment was cloned and subjected to sequence analysis. Normal and mutated alleles of fibrinogen Bern I were obtained, showing a G + T transition in the ...
Protocol: Genome-scale CRISPR-Cas9 Knockout
... through either homology-directed repair (HDR) or more often, non-homologous endjoining (NHEJ)29. HDR precisely repairs the DSB using a homologous DNA template, whereas NHEJ is error-prone and introduces indels. When Cas9 is targeted to a coding region, loss-of-function (LOF) mutations can occur as a ...
... through either homology-directed repair (HDR) or more often, non-homologous endjoining (NHEJ)29. HDR precisely repairs the DSB using a homologous DNA template, whereas NHEJ is error-prone and introduces indels. When Cas9 is targeted to a coding region, loss-of-function (LOF) mutations can occur as a ...
Population Differences in the Polyalanine Domain and 6
... no abnormal magnetic resonance imaging findings) almost identical to that of her brother (sacral dimple with a bony outgrowth and no abnormal magnetic resonance imaging findings). Chromosomal microdeletions affecting the HLXB9 gene, which have been described in some Currarino patients (4 ), can be d ...
... no abnormal magnetic resonance imaging findings) almost identical to that of her brother (sacral dimple with a bony outgrowth and no abnormal magnetic resonance imaging findings). Chromosomal microdeletions affecting the HLXB9 gene, which have been described in some Currarino patients (4 ), can be d ...
References and Data Structures
... structures. An array that contains a set of hash references is an example. An example: an array of genes on a chromosome, where the position of the gene in the array corresponds to its relative position on the chromosome. Information about each gene is stored in a hash. For example, assume that INFI ...
... structures. An array that contains a set of hash references is an example. An example: an array of genes on a chromosome, where the position of the gene in the array corresponds to its relative position on the chromosome. Information about each gene is stored in a hash. For example, assume that INFI ...
Traversing the conceptual divide between biological and
... physically interact with Ubx by a variety of strategies, including phage display, immunoprecipitation, pull-down assays and gel retardation analysis. Interestingly, Ubx and DIP1 are coexpressed in the same embryonic tissues and are both localized to the nucleus. Further, ectopic expression of DIP1 i ...
... physically interact with Ubx by a variety of strategies, including phage display, immunoprecipitation, pull-down assays and gel retardation analysis. Interestingly, Ubx and DIP1 are coexpressed in the same embryonic tissues and are both localized to the nucleus. Further, ectopic expression of DIP1 i ...
Amino Acid Transporters and Release of Hydrophobic Amino Acids
... synthesized peptide made of aspartate and arginine (multi-L-arginyl-poly [L-aspartic acid]) [11]. Cyanophycinase produces β-aspartyl-arginine, which is hydrolyzed by isoaspartyl dipeptidase in the vegetative cells [3]. Thus, glutamine and β-aspartyl-arginine (and perhaps also aspartate and arginine) ...
... synthesized peptide made of aspartate and arginine (multi-L-arginyl-poly [L-aspartic acid]) [11]. Cyanophycinase produces β-aspartyl-arginine, which is hydrolyzed by isoaspartyl dipeptidase in the vegetative cells [3]. Thus, glutamine and β-aspartyl-arginine (and perhaps also aspartate and arginine) ...
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... Some studies have reported evidence for higher recombination rates in genes with worker-biased expression [4,39]. However, the cause of these associations is unclear and several questions remain. In particular, it is not known whether worker-biased genes are preferentially located in regions of high ...
... Some studies have reported evidence for higher recombination rates in genes with worker-biased expression [4,39]. However, the cause of these associations is unclear and several questions remain. In particular, it is not known whether worker-biased genes are preferentially located in regions of high ...